{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T08:23:46Z","timestamp":1770452626155,"version":"3.49.0"},"reference-count":73,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T00:00:00Z","timestamp":1525651200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["322693"],"award-info":[{"award-number":["322693"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["KK.01.1.1.01.0006"],"award-info":[{"award-number":["KK.01.1.1.01.0006"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2018.00991","type":"journal-article","created":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T04:17:55Z","timestamp":1525666675000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":18,"title":["Murine CMV Expressing the High Affinity NKG2D Ligand MULT-1: A Model for the Development of Cytomegalovirus-Based Vaccines"],"prefix":"10.3389","volume":"9","author":[{"given":"Lea","family":"Hir\u0161l","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilija","family":"Brizi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tina","family":"Jenu\u0161","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanda","family":"Jurani\u0107 Lisni\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna Julia","family":"Reichel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slaven","family":"Jurkovi\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Astrid","family":"Krmpoti\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stipan","family":"Jonji\u0107","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2018,5,7]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9780511545313.045","article-title":"Chapter 36: Persistence in the population: epidemiology and transmission","volume-title":"Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis","author":"Boppana","year":"2007"},{"key":"B2","doi-asserted-by":"publisher","first-page":"3607","DOI":"10.1001\/jama.1989.03420240121038","article-title":"The indirect effects of cytomegalovirus infection on the outcome of organ transplantation","volume":"261","author":"Rubin","year":"1989","journal-title":"JAMA"},{"key":"B3","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/j.jcv.2005.09.015","article-title":"Congenital cytomegalovirus infection following first trimester maternal infection: symptoms at birth and outcome","volume":"35","author":"Pass","year":"2006","journal-title":"J Clin Virol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1713","DOI":"10.1084\/jem.179.5.1713","article-title":"Antibodies are not essential for the resolution of primary cytomegalovirus infection but limit dissemination of recurrent virus","volume":"179","author":"Jonjic","year":"1994","journal-title":"J Exp Med"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1084\/jem.188.6.1047","article-title":"Hierarchical and redundant lymphocyte subset control precludes cytomegalovirus replication during latent infection","volume":"188","author":"Polic","year":"1998","journal-title":"J Exp Med"},{"key":"B6","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1038\/nri932","article-title":"Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance","volume":"2","author":"Reddehase","year":"2002","journal-title":"Nat Rev Immunol"},{"key":"B7","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S2055-6640(20)30872-4","article-title":"Cytomegalovirus vaccines under clinical development","volume":"2","author":"Schleiss","year":"2016","journal-title":"J Virus Erad"},{"key":"B8","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1038\/nri1199","article-title":"Roles of the NKG2D immunoreceptor and its ligands","volume":"3","author":"Raulet","year":"2003","journal-title":"Nat Rev Immunol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1038\/ni858","article-title":"Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D","volume":"3","author":"Diefenbach","year":"2002","journal-title":"Nat Immunol"},{"key":"B10","doi-asserted-by":"publisher","first-page":"1150","DOI":"10.1038\/ni857","article-title":"NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation","volume":"3","author":"Gilfillan","year":"2002","journal-title":"Nat Immunol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1016\/S1074-7613(00)80222-8","article-title":"Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice","volume":"12","author":"Cerwenka","year":"2000","journal-title":"Immunity"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1038\/nature03884","article-title":"The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor","volume":"436","author":"Gasser","year":"2005","journal-title":"Nature"},{"key":"B13","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1111\/j.0105-2896.2010.00893.x","article-title":"Effect of NKG2D ligand expression on host immune responses","volume":"235","author":"Champsaur","year":"2010","journal-title":"Immunol Rev"},{"key":"B14","doi-asserted-by":"publisher","first-page":"362","DOI":"10.3390\/v1030362","article-title":"The natural selection of herpesviruses and virus-specific NK cell receptors","volume":"1","author":"Sun","year":"2009","journal-title":"Viruses"},{"key":"B15","doi-asserted-by":"publisher","first-page":"85","DOI":"10.3389\/fimmu.2011.00085","article-title":"Manipulation of NKG2D ligands by cytomegaloviruses: impact on innate and adaptive immune response","volume":"2","author":"Slavuljica","year":"2011","journal-title":"Front Immunol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.1084\/jem.20040583","article-title":"The cytomegalovirus m155 gene product subverts natural killer cell antiviral protection by disruption of H60-NKG2D interactions","volume":"200","author":"Lodoen","year":"2004","journal-title":"J Exp Med"},{"key":"B17","doi-asserted-by":"publisher","first-page":"2920","DOI":"10.1128\/JVI.79.5.2920-2930.2005","article-title":"Selective down-regulation of the NKG2D ligand H60 by mouse cytomegalovirus m155 glycoprotein","volume":"79","author":"Hasan","year":"2005","journal-title":"J Virol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1084\/jem.20041617","article-title":"NK cell activation through the NKG2D ligand MULT-1 is selectively prevented by the glycoprotein encoded by mouse cytomegalovirus gene m145","volume":"201","author":"Krmpotic","year":"2005","journal-title":"J Exp Med"},{"key":"B19","doi-asserted-by":"publisher","first-page":"1843","DOI":"10.1084\/jem.20060514","article-title":"The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60","volume":"203","author":"Lenac","year":"2006","journal-title":"J Exp Med"},{"key":"B20","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.molimm.2009.02.010","article-title":"Promiscuity of MCMV immunoevasin of NKG2D: m138\/fcr-1 down-modulates RAE-1epsilon in addition to MULT-1 and H60","volume":"47","author":"Arapovic","year":"2009","journal-title":"Mol Immunol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"4532","DOI":"10.1172\/JCI43961","article-title":"Recombinant mouse cytomegalovirus expressing a ligand for the NKG2D receptor is attenuated and has improved vaccine properties","volume":"120","author":"Slavuljica","year":"2010","journal-title":"J Clin Invest"},{"key":"B22","doi-asserted-by":"publisher","first-page":"16550","DOI":"10.1073\/pnas.1310215110","article-title":"Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1gamma","volume":"110","author":"Trsan","year":"2013","journal-title":"Proc Natl Acad Sci U S A"},{"key":"B23","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1002\/eji.201746964","article-title":"Cytomegalovirus vector expressing RAE-1gamma induces enhanced anti-tumor capacity of murine CD8(+) T cells","volume":"47","author":"Trsan","year":"2017","journal-title":"Eur J Immunol"},{"key":"B24","doi-asserted-by":"publisher","first-page":"e1006015","DOI":"10.1371\/journal.ppat.1006015","article-title":"Activation of innate and adaptive immunity by a recombinant human cytomegalovirus strain expressing an NKG2D ligand","volume":"12","author":"Tomic","year":"2016","journal-title":"PLoS Pathog"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1128\/JVI.02087-09","article-title":"Immune evasion proteins of murine cytomegalovirus preferentially affect cell surface display of recently generated peptide presentation complexes","volume":"84","author":"Lemmermann","year":"2010","journal-title":"J Virol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/978-1-60761-652-8_30","article-title":"En passant mutagenesis: a two step markerless red recombination system","volume":"634","author":"Tischer","year":"2010","journal-title":"Methods Mol Biol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1007\/978-1-59745-570-1_8","article-title":"Dissection of the antiviral NK cell response by MCMV mutants","volume":"415","author":"Jonjic","year":"2008","journal-title":"Methods Mol Biol"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1002\/0471142735.im1907s43","article-title":"A mouse model for cytomegalovirus infection","author":"Brune","year":"2001","journal-title":"Curr Protoc Immunol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1016\/j.immuni.2009.06.017","article-title":"Altered NK cell development and enhanced NK cell-mediated resistance to mouse cytomegalovirus in NKG2D-deficient mice","volume":"31","author":"Zafirova","year":"2009","journal-title":"Immunity"},{"key":"B30","doi-asserted-by":"publisher","first-page":"e1002313","DOI":"10.1371\/journal.ppat.1002313","article-title":"Non-hematopoietic cells in lymph nodes drive memory CD8 T cell inflation during murine cytomegalovirus infection","volume":"7","author":"Torti","year":"2011","journal-title":"PLoS Pathog"},{"key":"B31","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/0092-8674(94)90169-4","article-title":"T cell receptor antagonist peptides induce positive selection","volume":"76","author":"Hogquist","year":"1994","journal-title":"Cell"},{"key":"B32","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1089\/hyb.1984.3.301","article-title":"Establishment of monoclonal anti-Nk-1.1 antibody","volume":"3","author":"Koo","year":"1984","journal-title":"Hybridoma"},{"key":"B33","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.1084\/jem.176.6.1693","article-title":"Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte\/macrophage colony-stimulating factor","volume":"176","author":"Inaba","year":"1992","journal-title":"J Exp Med"},{"key":"B34","doi-asserted-by":"crossref","first-page":"5457","DOI":"10.1128\/JVI.64.11.5457-5464.1990","article-title":"Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes","volume":"64","author":"Jonjic","year":"1990","journal-title":"J Virol"},{"key":"B35","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1084\/jem.20021973","article-title":"NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules","volume":"197","author":"Lodoen","year":"2003","journal-title":"J Exp Med"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1126\/science.1070884","article-title":"Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors","volume":"296","author":"Arase","year":"2002","journal-title":"Science"},{"key":"B37","doi-asserted-by":"publisher","first-page":"11495","DOI":"10.1128\/JVI.74.24.11495-11503.2000","article-title":"Enrichment of immediate-early 1 (m123\/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungs","volume":"74","author":"Holtappels","year":"2000","journal-title":"J Virol"},{"key":"B38","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1038\/nri.2016.38","article-title":"T cell responses to cytomegalovirus","volume":"16","author":"Klenerman","year":"2016","journal-title":"Nat Rev Immunol"},{"key":"B39","doi-asserted-by":"publisher","first-page":"2255","DOI":"10.1128\/JVI.78.5.2255-2264.2004","article-title":"Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses","volume":"78","author":"Karrer","year":"2004","journal-title":"J Virol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1038\/nm.1935","article-title":"Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge","volume":"15","author":"Hansen","year":"2009","journal-title":"Nat Med"},{"key":"B41","doi-asserted-by":"publisher","first-page":"e1275","DOI":"10.1371\/journal.pntd.0001275","article-title":"A replicating cytomegalovirus-based vaccine encoding a single Ebola virus nucleoprotein CTL epitope confers protection against Ebola virus","volume":"5","author":"Tsuda","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"B42","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1158\/2326-6066.CIR-14-0044","article-title":"Cytomegalovirus-based vaccine expressing a modified tumor antigen induces potent tumor-specific CD8(+) T-cell response and protects mice from melanoma","volume":"3","author":"Qiu","year":"2015","journal-title":"Cancer Immunol Res"},{"key":"B43","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1093\/oxfordjournals.jbchem.a021517","article-title":"Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain","volume":"120","author":"Nomura","year":"1996","journal-title":"J Biochem"},{"key":"B44","doi-asserted-by":"publisher","first-page":"4079","DOI":"10.4049\/jimmunol.169.8.4079","article-title":"Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D","volume":"169","author":"Carayannopoulos","year":"2002","journal-title":"J Immunol"},{"key":"B45","doi-asserted-by":"publisher","first-page":"1678","DOI":"10.4049\/jimmunol.180.3.1678","article-title":"Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D","volume":"180","author":"Takada","year":"2008","journal-title":"J Immunol"},{"key":"B46","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1084\/jem.20081335","article-title":"Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress","volume":"206","author":"Nice","year":"2009","journal-title":"J Exp Med"},{"key":"B47","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1615\/CritRevImmunol.2014010604","article-title":"NK cells and their ability to modulate T cells during virus infections","volume":"34","author":"Cook","year":"2014","journal-title":"Crit Rev Immunol"},{"key":"B48","doi-asserted-by":"publisher","first-page":"8826","DOI":"10.1073\/pnas.092258599","article-title":"Recognition of a virus-encoded ligand by a natural killer cell activation receptor","volume":"99","author":"Smith","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"B49","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.1084\/jem.20091193","article-title":"Innate immunity defines the capacity of antiviral T cells to limit persistent infection","volume":"207","author":"Andrews","year":"2010","journal-title":"J Exp Med"},{"key":"B50","doi-asserted-by":"publisher","first-page":"2165","DOI":"10.1128\/JVI.06042-11","article-title":"The NK cell response to mouse cytomegalovirus infection affects the level and kinetics of the early CD8(+) T-cell response","volume":"86","author":"Mitrovic","year":"2012","journal-title":"J Virol"},{"key":"B51","doi-asserted-by":"publisher","first-page":"4931","DOI":"10.1128\/JVI.02127-07","article-title":"The early kinetics of cytomegalovirus-specific CD8+ T-cell responses are not affected by antigen load or the absence of perforin or gamma interferon","volume":"82","author":"Andrews","year":"2008","journal-title":"J Virol"},{"key":"B52","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1002\/eji.201343946","article-title":"Viral inoculum dose impacts memory T-cell inflation","volume":"44","author":"Redeker","year":"2014","journal-title":"Eur J Immunol"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e1002295","DOI":"10.1371\/journal.ppat.1002295","article-title":"Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus","volume":"7","author":"Snyder","year":"2011","journal-title":"PLoS Pathog"},{"key":"B54","doi-asserted-by":"publisher","first-page":"383","DOI":"10.4049\/jimmunol.1600478","article-title":"Blocking virus replication during acute murine cytomegalovirus infection paradoxically prolongs antigen presentation and increases the CD8+ T cell response by preventing type I IFN-dependent depletion of dendritic cells","volume":"198","author":"Loo","year":"2017","journal-title":"J Immunol"},{"key":"B55","doi-asserted-by":"publisher","first-page":"e9681","DOI":"10.1371\/journal.pone.0009681","article-title":"Cross-presentation of a spread-defective MCMV is sufficient to prime the majority of virus-specific CD8+ T cells","volume":"5","author":"Snyder","year":"2010","journal-title":"PLoS One"},{"key":"B56","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.immuni.2008.07.017","article-title":"Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells","volume":"29","author":"Snyder","year":"2008","journal-title":"Immunity"},{"key":"B57","doi-asserted-by":"publisher","first-page":"1994","DOI":"10.1099\/vir.0.031815-0","article-title":"Antigen-presenting cells of haematopoietic origin prime cytomegalovirus-specific CD8 T-cells but are not sufficient for driving memory inflation during viral latency","volume":"92","author":"Seckert","year":"2011","journal-title":"J Gen Virol"},{"key":"B58","doi-asserted-by":"publisher","first-page":"2612","DOI":"10.1002\/eji.201041075","article-title":"Batf3 transcription factor-dependent DC subsets in murine CMV infection: differential impact on T-cell priming and memory inflation","volume":"41","author":"Torti","year":"2011","journal-title":"Eur J Immunol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1038\/nri3405","article-title":"Molecular mechanisms of T cell co-stimulation and co-inhibition","volume":"13","author":"Chen","year":"2013","journal-title":"Nat Rev Immunol"},{"key":"B60","doi-asserted-by":"publisher","first-page":"13062","DOI":"10.1128\/JVI.78.23.13062-13071.2004","article-title":"Identification of a mouse cytomegalovirus gene selectively targeting CD86 expression on antigen-presenting cells","volume":"78","author":"Loewendorf","year":"2004","journal-title":"J Virol"},{"key":"B61","doi-asserted-by":"publisher","first-page":"8422","DOI":"10.4049\/jimmunol.177.12.8422","article-title":"Viral interference with B7-1 costimulation: a new role for murine cytomegalovirus fc receptor-1","volume":"177","author":"Mintern","year":"2006","journal-title":"J Immunol"},{"key":"B62","doi-asserted-by":"publisher","first-page":"3874","DOI":"10.4049\/jimmunol.1003231","article-title":"Differential B7-CD28 costimulatory requirements for stable and inflationary mouse cytomegalovirus-specific memory CD8 T cell populations","volume":"186","author":"Arens","year":"2011","journal-title":"J Immunol"},{"key":"B63","doi-asserted-by":"publisher","first-page":"e07486","DOI":"10.7554\/eLife.07486","article-title":"The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansion","volume":"4","author":"Welten","year":"2015","journal-title":"Elife"},{"key":"B64","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1038\/85321","article-title":"Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells","volume":"2","author":"Groh","year":"2001","journal-title":"Nat Immunol"},{"key":"B65","doi-asserted-by":"publisher","first-page":"2825","DOI":"10.4049\/jimmunol.175.5.2825","article-title":"Costimulation through NKG2D enhances murine CD8+ CTL function: similarities and differences between NKG2D and CD28 costimulation","volume":"175","author":"Markiewicz","year":"2005","journal-title":"J Immunol"},{"key":"B66","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1002\/eji.201646805","article-title":"NKG2D stimulation of CD8(+) T cells during priming promotes their capacity to produce cytokines in response to viral infection in mice","volume":"47","author":"Kavazovic","year":"2017","journal-title":"Eur J Immunol"},{"key":"B67","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1038\/nm.2683","article-title":"NKG2D signaling on CD8(+) T cells represses T-bet and rescues CD4-unhelped CD8(+) T cell memory recall but not effector responses","volume":"18","author":"Zloza","year":"2012","journal-title":"Nat Med"},{"key":"B68","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.4049\/jimmunol.1700799","article-title":"Cutting edge: NKG2D signaling enhances NK cell responses but alone is insufficient to drive expansion during mouse cytomegalovirus infection","volume":"199","author":"Nabekura","year":"2017","journal-title":"J Immunol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1093\/infdis\/171.5.1115","article-title":"Antiviral antibody responses and intrauterine transmission after primary maternal cytomegalovirus infection","volume":"171","author":"Boppana","year":"1995","journal-title":"J Infect Dis"},{"key":"B70","doi-asserted-by":"publisher","first-page":"1960","DOI":"10.1002\/jmv.23691","article-title":"Slow increase in IgG avidity correlates with prevention of human cytomegalovirus transmission to the fetus","volume":"85","author":"Furione","year":"2013","journal-title":"J Med Virol"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201847526","article-title":"Brain-resident memory CD8(+) T cells induced by congenital CMV infection prevent brain pathology and virus reactivation","author":"Brizic","year":"2018","journal-title":"Eur J Immunol"},{"key":"B72","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1038\/ni.2388","article-title":"TGF-beta is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy","volume":"13","author":"Marcoe","year":"2012","journal-title":"Nat Immunol"},{"key":"B73","doi-asserted-by":"publisher","first-page":"759765","DOI":"10.1155\/2012\/759765","article-title":"Development of murine hepatic NK cells during ontogeny: comparison with spleen NK cells","volume":"2012","author":"Wu","year":"2012","journal-title":"Clin Dev Immunol"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fimmu.2018.00991\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T16:52:11Z","timestamp":1604249531000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fimmu.2018.00991\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,7]]},"references-count":73,"alternative-id":["10.3389\/fimmu.2018.00991"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2018.00991","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,7]]},"article-number":"991"}}