{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T12:30:59Z","timestamp":1784896259941,"version":"3.55.0"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T00:00:00Z","timestamp":1530576000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2018.01540","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T04:21:18Z","timestamp":1530591678000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":40,"title":["Histamine Released From Skin-Infiltrating Basophils but Not Mast Cells Is Crucial for Acquired Tick Resistance in Mice"],"prefix":"10.3389","volume":"9","author":[{"given":"Yuya","family":"Tabakawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuya","family":"Ohta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soichiro","family":"Yoshikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth J.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayoko","family":"Yamaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenji","family":"Ishiwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Kawano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Yamanishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Ohtsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naohiro","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotaka","family":"Kanuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Karasuyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,7,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1146\/annurev.ento.44.1.51","article-title":"Emerging and resurging vector-borne diseases","volume":"44","author":"Gratz","year":"1999","journal-title":"Annu Rev Entomol"},{"key":"B2","doi-asserted-by":"publisher","first-page":"6938","DOI":"10.2741\/3200","article-title":"Overview: ticks as vectors of pathogens that cause disease in humans and animals","volume":"13","author":"de la Fuente","year":"2008","journal-title":"Front Biosci"},{"key":"B3","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1086\/319347","article-title":"Ticks and tickborne bacterial diseases in humans: an emerging infectious threat","volume":"32","author":"Parola","year":"2001","journal-title":"Clin Infect Dis"},{"key":"B4","doi-asserted-by":"publisher","first-page":"43","DOI":"10.3389\/fcimb.2013.00043","article-title":"Tick salivary compounds: their role in modulation of host defences and pathogen transmission","volume":"3","author":"Kazim\u00edrov\u00e1","year":"2013","journal-title":"Front Cell Infect Microbiol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1016\/S0020-7519(99)00042-9","article-title":"Tick modulation of host immunity: an important factor in pathogen transmission","volume":"29","author":"Wikel","year":"1999","journal-title":"Int J Parasitol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1146\/annurev.en.41.010196.000245","article-title":"Host immunity to ticks","volume":"41","author":"Wikel","year":"1996","journal-title":"Annu Rev Entomol"},{"key":"B7","doi-asserted-by":"crossref","first-page":"790","DOI":"10.4049\/jimmunol.129.2.790","article-title":"Ablation of immunity to Amblyomma americanum by anti-basophil serum: cooperation between basophils and eosinophils in expression of immunity to ectoparasites (ticks) in guinea pigs","volume":"129","author":"Brown","year":"1982","journal-title":"J Immunol"},{"key":"B8","doi-asserted-by":"crossref","first-page":"259","DOI":"10.4049\/jimmunol.144.1.259","article-title":"Necessity of IgE antibodies and mast cells for manifestation of resistance against larval Haemaphysalis longicornis ticks in mice","volume":"144","author":"Matsuda","year":"1990","journal-title":"J Immunol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"2867","DOI":"10.1172\/JCI42680","article-title":"Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks","volume":"120","author":"Wada","year":"2010","journal-title":"J Clin Invest"},{"key":"B10","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/0020-7519(73)90024-6","article-title":"Tick resistance: basophils in skin reactions of resistant guinea pigs","volume":"3","author":"Allen","year":"1973","journal-title":"Int J Parasitol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1189\/jlb.0609400","article-title":"Basophils preferentially express mouse mast cell protease 11 among the mast cell tryptase family in contrast to mast cells","volume":"86","author":"Ugajin","year":"2009","journal-title":"J Leukoc Biol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/BF00927849","article-title":"The relation between skin histamine concentration, histamine sensitivity, and the resistance of cattle to the tick, Boophilus microplus","volume":"59","author":"Willadsen","year":"1979","journal-title":"Z Parasitenkd"},{"key":"B13","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/0014-4894(69)90130-1","article-title":"Boophilus microplus: antihistaminic and tranquillizing drugs and cattle resistance","volume":"26","author":"Tatchell","year":"1969","journal-title":"Exp Parasitol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1017\/S0031182000000950","article-title":"Boophilus microplus: the effect of histamine on the attachment of cattle-tick larvae \u2013 studies in vivo and in vitro","volume":"80","author":"Kemp","year":"1980","journal-title":"Parasitology"},{"key":"B15","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1080\/00034983.1982.11687525","article-title":"Histamine content of tick attachment sites and the effects of H1 and H2 histamine antagonists on the expression of resistance","volume":"76","author":"Wikel","year":"1982","journal-title":"Ann Trop Med Parasitol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1016\/S0002-9440(10)62055-X","article-title":"Mast cell-deficient W-sash c-kit mutant Kit W-sh\/W-sh mice as a model for investigating mast cell biology in vivo","volume":"167","author":"Grimbaldeston","year":"2005","journal-title":"Am J Pathol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/S0014-5793(01)02663-1","article-title":"Mice lacking histidine decarboxylase exhibit abnormal mast cells","volume":"502","author":"Ohtsu","year":"2001","journal-title":"FEBS Lett"},{"key":"B18","doi-asserted-by":"publisher","first-page":"13316","DOI":"10.1073\/pnas.93.23.13316","article-title":"Impaired locomotor activity and exploratory behavior in mice lacking histamine H1 receptors","volume":"93","author":"Inoue","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"B19","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.3389\/fimmu.2017.01348","article-title":"Skin CD4+ memory T cells play an essential role in acquired anti-tick immunity through interleukin-3-mediated basophil recruitment to tick-feeding sites","volume":"8","author":"Ohta","year":"2017","journal-title":"Front Immunol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1002\/bies.20174","article-title":"Mammalian histidine decarboxylase: from structure to function","volume":"27","author":"Moya-Garcia","year":"2005","journal-title":"Bioessays"},{"key":"B21","doi-asserted-by":"publisher","first-page":"2816","DOI":"10.1182\/blood-2008-05-154773","article-title":"Basophil effector function and homeostasis during helminth infection","volume":"113","author":"Ohnmacht","year":"2009","journal-title":"Blood"},{"key":"B22","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1071\/BI9760499","article-title":"Boophilus microplus: cellular responses to larval attachment and their relationship to host resistance","volume":"29","author":"Schleger","year":"1976","journal-title":"Aust J Biol Sci"},{"key":"B23","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/S0167-4838(00)00168-0","article-title":"Tick histamine-binding proteins: lipocalins with a second binding cavity","volume":"1482","author":"Paesen","year":"2000","journal-title":"Biochim Biophys Acta"},{"key":"B24","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1017\/S0031182000048241","article-title":"Boophilus microplus: rejection of larvae from British breed cattle","volume":"76","author":"Koudstaal","year":"1978","journal-title":"Parasitology"},{"key":"B25","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1017\/S0031182000050617","article-title":"In vitro feeding of Dermacentor andersoni (Stiles): effects of histamine and other mediators","volume":"86","author":"Paine","year":"1983","journal-title":"Parasitology"},{"key":"B26","doi-asserted-by":"publisher","first-page":"533","DOI":"10.2332\/allergolint.13-RA-0675","article-title":"The role of histamine H1 and H4 receptors in atopic dermatitis: from basic research to clinical study","volume":"63","author":"Ohsawa","year":"2014","journal-title":"Allergol Int"},{"key":"B27","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s40348-015-0027-1","article-title":"Expression and function of histamine and its receptors in atopic dermatitis","volume":"2","author":"Albrecht","year":"2015","journal-title":"Mol Cell Pediatr"},{"key":"B28","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/S0923-1811(97)00043-1","article-title":"The mast cell products histamine and serotonin stimulate and TNF-alpha inhibits the proliferation of murine epidermal keratinocytes in situ","volume":"16","author":"Maurer","year":"1997","journal-title":"J Dermatol Sci"},{"key":"B29","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.4049\/jimmunol.134.2.1160","article-title":"Rejection of ticks from guinea pigs by anti-hapten-antibody-mediated degranulation of basophils at cutaneous basophil hypersensitivity sites: role of mediators other than histamine","volume":"134","author":"Brown","year":"1985","journal-title":"J Immunol"},{"key":"B30","unstructured":"BagnallBG SydneyUniversity of SydneyCutaneous Immunity to the Tick Ixodes holocyclus1975"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.1111\/brv.12384","article-title":"Tick attachment cement \u2013 reviewing the mysteries of a biological skin plug system","volume":"2","author":"Suppan","year":"2017","journal-title":"Biol Rev Camb Philos Soc"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2018.01540\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T13:41:12Z","timestamp":1693748472000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2018.01540\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,3]]},"references-count":31,"alternative-id":["10.3389\/fimmu.2018.01540"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2018.01540","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,3]]},"article-number":"1540"}}