{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:22:37Z","timestamp":1790716957574,"version":"4.1.0"},"reference-count":93,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T00:00:00Z","timestamp":1542585600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2018.02570","type":"journal-article","created":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T09:24:50Z","timestamp":1542619490000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":59,"title":["Chronic Mucocutaneous Candidiasis in Autoimmune Polyendocrine Syndrome Type 1"],"prefix":"10.3389","volume":"9","author":[{"given":"Linda","family":"Humbert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjorie","family":"Cornu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Proust-Lemoine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagadeesh","family":"Bayry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Wemeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Christine","family":"Vantyghem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boualem","family":"Sendid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,11,19]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1210\/jcem-16-10-1374","article-title":"The syndrome of familial juvenile hypoadrenocorticism, hypoparathyroidism and superficial moniliasis","volume":"16","author":"Whitaker","year":"1956","journal-title":"J Clin Endocrinol Metab."},{"key":"B2","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3928\/0090-4481-19800401-07","article-title":"Autoimmune polyglandular syndromes","volume":"9","author":"Neufeld","year":"1980","journal-title":"Pediatr Ann."},{"key":"B3","doi-asserted-by":"publisher","first-page":"e651","DOI":"10.1016\/j.lpm.2012.10.005","article-title":"Polyglandular autoimmune syndrome type I","volume":"41","author":"Proust-Lemoine","year":"2012","journal-title":"Presse M\u00e9d"},{"key":"B4","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1038\/ng0994-83","article-title":"An autosomal locus causing autoimmune disease: autoimmune polyglandular disease type I assigned to chromosome 21","volume":"8","author":"Aaltonen","year":"1994","journal-title":"Nat Genet"},{"key":"B5","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1038\/ng1297-399","article-title":"An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains","volume":"17","year":"1997","journal-title":"Nat Genet."},{"key":"B6","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1016\/j.coi.2004.09.009","article-title":"Aire: an update","volume":"16","author":"Su","year":"2004","journal-title":"Curr Opin Immunol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"3299","DOI":"10.1093\/hmg\/11.26.3299","article-title":"Systematic mutagenesis of the functional domains of AIRE reveals their role in intracellular targeting","volume":"11","author":"Ramsey","year":"2002","journal-title":"Hum Mol Genet"},{"key":"B8","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1080\/17402520500212589","article-title":"The development of mouse APECED models provides new insight into the role of AIRE in immune regulation","volume":"12","author":"Pereira","year":"2005","journal-title":"Clin Dev Immunol."},{"key":"B9","first-page":"879","article-title":"Genetic homogeneity of autoimmune polyglandular disease type I","volume":"59","author":"Bj\u00f6rses","year":"1996","journal-title":"Am J Hum Genet"},{"key":"B10","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1086\/302765","article-title":"Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis\u2013ectodermal dystrophy protein","volume":"66","author":"Bj\u00f6rses","year":"2000","journal-title":"Am J Hum Genet"},{"key":"B11","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1002\/humu.1176","article-title":"APECED mutations in the autoimmune regulator (AIRE) gene","volume":"18","author":"Heino","year":"2001","journal-title":"Hum Mutat."},{"key":"B12","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1007\/s00251-017-0995-5","article-title":"A new mutation site in the AIRE gene causes autoimmune polyendocrine syndrome type 1","volume":"69","author":"Zhu","year":"2017","journal-title":"Immunogenetics"},{"key":"B13","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1210\/jcem-64-3-494","article-title":"Adrenal and steroidal cell antibodies in patients with autoimmune polyglandular disease type I and risk of adrenocortical and ovarian failure","volume":"64","author":"Ahonen","year":"1987","journal-title":"J Clin Endocrinol Metab"},{"key":"B14","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1007\/s004390050846","article-title":"A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients","volume":"103","author":"Rosatelli","year":"1998","journal-title":"Hum Genet"},{"key":"B15","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1136\/jmg.29.11.824","article-title":"Polyglandular autoimmune syndrome type I among Iranian Jews","volume":"29","author":"Zlotogora","year":"1992","journal-title":"J Med Genet"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1086\/302145","article-title":"A common and recurrent 13-bp deletion in the autoimmune regulator gene in British kindreds with autoimmune polyendocrinopathy type 1","volume":"63","author":"Pearce","year":"1998","journal-title":"Am J Hum Genet"},{"key":"B17","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1046\/j.1365-2265.2001.01201.x","article-title":"Autoimmune polyendocrine syndrome type 1 (APS I) in Norway","volume":"54","author":"Myhre","year":"2001","journal-title":"Clin Endocrinol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"1343","DOI":"10.1515\/JPEM,2006.19.11.1343","article-title":"Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in the Irish population","volume":"19","author":"Dominguez","year":"2006","journal-title":"J Pediatr Endocrinol Metab"},{"key":"B19","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1210\/jc.2006-1873","article-title":"Autoimmune polyendocrine syndrome type 1 in Norway: phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene","volume":"92","author":"Wolff","year":"2007","journal-title":"J Clin Endocrinol Metab."},{"key":"B20","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1159\/000363537","article-title":"Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy: report of seven additional sicilian patients and overview of the overall series from sicily","volume":"82","author":"Valenzise","year":"2014","journal-title":"Horm Res Paediatr."},{"key":"B21","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1172\/jci.insight.88782","article-title":"Redefined clinical features and diagnostic criteria in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy","volume":"1","author":"Ferre","year":"2016","journal-title":"JCI Insight"},{"key":"B22","doi-asserted-by":"publisher","first-page":"2568","DOI":"10.1210\/jcem.87.6.8564","article-title":"AIRE mutations and human leukocyte antigen genotypes as determinants of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy phenotype","volume":"87","author":"Halonen","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"B23","doi-asserted-by":"publisher","first-page":"2843","DOI":"10.1210\/jc.2005-2611","article-title":"Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy","volume":"91","author":"Perheentupa","year":"2006","journal-title":"J Clin Endocrinol Metab."},{"key":"B24","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1016\/j.chom.2017.03.006","article-title":"Autoreactive T cells and chronic fungal infection drive esophageal carcinogenesis","volume":"21","author":"Zhu","year":"2017","journal-title":"Cell Host Microbe"},{"key":"B25","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1684\/ejd.2010.0910","article-title":"Chronic mucocutaneous candidiasis, from bench to bedside","volume":"20","author":"Eyerich","year":"2010","journal-title":"Eur J Dermatol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1001\/archpedi.1929.01930080104011","article-title":"Chronic tetany and chronic mycelial stomatitis in a child aged four and one-half years","volume":"38","author":"Thorpe","year":"1929","journal-title":"Am J Dis Child"},{"key":"B27","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1128\/CMR.17.4.729-759.2004.","article-title":"Immunopathogenesis of oropharyngeal candidiasis in human immunodeficiency virus infection","volume":"17","author":"de Repentigny","year":"2004","journal-title":"Clin Microbiol Rev."},{"key":"B28","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1111\/1469-0691.12039","article-title":"ESCMID* guideline for the diagnosis and management of Candida diseases 2012: non-neutropenic adult patients","volume":"18","author":"Cornely","year":"2012","journal-title":"Clin Microbiol Infect."},{"key":"B29","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1080\/13693780701616023.","article-title":"Chronic mucocutaneous candidiasis and oesophageal cancer","volume":"46","author":"Rosa","year":"2008","journal-title":"Med Mycol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.18869\/acadpub.cmm.2.2.4","article-title":"Identification of Candida species in the oral cavity of diabetic patients","volume":"2","author":"Mohammadi","year":"2016","journal-title":"Curr Med Mycol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1097\/ACI.0b013e328358cc0b.","article-title":"Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis","volume":"12","author":"Puel","year":"2012","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1007\/s10875-015-0201-1.","article-title":"Primary immunodeficiency diseases: an update on the classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015","volume":"35","author":"Picard","year":"2015","journal-title":"J Clin Immunol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"e114","DOI":"10.1038\/cti.2016.71","article-title":"Chronic mucocutaneous candidiasis disease associated with inborn errors of IL-17 immunity","volume":"5","author":"Okada","year":"2016","journal-title":"Clin Transl Immunol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1111\/j.1749-6632.2011.06387.x","article-title":"Hyper-IgE syndrome update","volume":"1250","author":"Sowerwine","year":"2012","journal-title":"Ann N Y Acad Sci"},{"key":"B35","doi-asserted-by":"publisher","first-page":"2046","DOI":"10.1056\/NEJMoa0905506","article-title":"Combined Immunodeficiency Associated with DOCK8 Mutations","volume":"361","author":"Zhang","year":"2009","journal-title":"N Engl J Med."},{"key":"B36","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1097\/ACI.0b013e32833fd718","article-title":"DOCK8 (Dedicator of cytokinesis 8) deficiency","volume":"10","author":"Su","year":"2010","journal-title":"Curr Opin Allergy Clin Immunol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1111\/j.1749-6632.2011.06295.x","article-title":"DOCK8 deficiency","volume":"1246","author":"Su","year":"2011","journal-title":"Ann N Y Acad Sci"},{"key":"B38","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/j.clim.2017.06.003","article-title":"DOCK8 deficiency: insights into pathophysiology, clinical features and management","volume":"181","author":"Biggs","year":"2017","journal-title":"Clin Immunol"},{"key":"B39","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1007\/s10875-015-0170-4","article-title":"A homozygous CARD9 mutation in a Brazilian patient with deep dermatophytosis","volume":"35","author":"Grumach","year":"2015","journal-title":"J Clin Immunol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1097\/INF.0000000000001028","article-title":"Successful granulocyte colony-stimulating factor treatment of relapsing Candida albicans meningoencephalitis caused by CARD9 deficiency","volume":"35","author":"Celmeli","year":"2016","journal-title":"Pediatr Infect Dis J"},{"key":"B41","doi-asserted-by":"publisher","first-page":"bcr2015214117","DOI":"10.1136\/bcr-2015-214117.","article-title":"Endogenous Candida endophthalmitis and osteomyelitis associated with CARD9 deficiency","volume":"2016","author":"Jones","year":"2016","journal-title":"BMJ Case Rep"},{"key":"B42","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1056\/NEJMoa0810719","article-title":"A homozygous CARD9 mutation in a family with susceptibility to fungal infections","volume":"361","author":"Glocker","year":"2009","journal-title":"N Engl J Med."},{"key":"B43","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1182\/blood-2012-08-450551","article-title":"Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency","volume":"121","author":"Drewniak","year":"2013","journal-title":"Blood"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1760","DOI":"10.1056\/NEJMoa0901053.","article-title":"Human Dectin-1 deficiency and mucocutaneous fungal infections","volume":"361","author":"Ferwerda","year":"2009","journal-title":"N Engl J Med."},{"key":"B45","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1093\/infdis\/jir458.","article-title":"Genetic variation in the Dectin-1\/CARD9 recognition pathway and susceptibility to candidemia","volume":"204","author":"Rosentul","year":"2011","journal-title":"J Infect Dis."},{"key":"B46","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1086\/604714","article-title":"Early stop polymorphism in human DECTIN-1 is associated with increased Candida colonization in hematopoietic stem cell transplant recipients","volume":"49","author":"Plantinga","year":"2009","journal-title":"Clin Infect Dis."},{"key":"B47","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/j.immuni.2010.05.001","article-title":"Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans","volume":"32","author":"Saijo","year":"2010","journal-title":"Immunity"},{"key":"B48","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1016\/S1473-3099(11)70217-1","article-title":"Insights into human antifungal immunity from primary immunodeficiencies","volume":"11","author":"Vinh","year":"2011","journal-title":"Lancet Infect Dis"},{"key":"B49","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.1136\/gutjnl-2011-301668","article-title":"Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial","volume":"61","author":"Hueber","year":"2012","journal-title":"Gut"},{"key":"B50","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1136\/gutjnl-2012-304154","article-title":"Secukinumab failure in Crohn's disease: the yeast connection?","volume":"62","author":"Colombel","year":"2013","journal-title":"Gut"},{"key":"B51","doi-asserted-by":"publisher","first-page":"1829","DOI":"10.1056\/NEJM19900628322260","article-title":"Clinical variation of Autoimmune Polyendocrinopathy\u2013Candidiasis\u2013Ectodermal Dystrophy (APECED) in a series of 68 patients","volume":"322","author":"Ahonen","year":"1990","journal-title":"N Engl J Med"},{"key":"B52","doi-asserted-by":"publisher","first-page":"1088","DOI":"10.1111\/j.1365-2133.2006.07166.x","article-title":"Dermatological manifestations of autoimmune polyendocrinopathy\u2013candidiasis\u2013ectodermal dystrophy syndrome","volume":"154","author":"Collins","year":"2006","journal-title":"Br J Dermatol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"2975","DOI":"10.1210\/jc.2016-1821","article-title":"A longitudinal follow-up of autoimmune polyendocrine syndrome type 1","volume":"101","author":"Bruserud","year":"2016","journal-title":"J Clin Endocrinol Metab"},{"key":"B54","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1210\/jcem.83.4.4682","article-title":"Autoimmune polyglandular syndrome type 1","volume":"83","author":"Betterle","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"B55","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1210\/jc.2011-2461","article-title":"Autoimmune polyendocrine syndrome type 1: an extensive longitudinal study in sardinian patients","volume":"97","author":"Meloni","year":"2012","journal-title":"J Clin Endocrinol Metab."},{"key":"B56","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1111\/j.1365-2796.2009.02090.x","article-title":"Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I","volume":"265","author":"Husebye","year":"2009","journal-title":"J Intern Med"},{"key":"B57","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1159\/000297714","article-title":"Autoimmune polyendocrine syndrome type 1 in North-Western France: AIRE gene mutation specificities and severe forms needing immunosuppressive therapies","volume":"74","author":"Proust-Lemoine","year":"2010","journal-title":"Horm Res Paediatr"},{"key":"B58","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1084\/jem.20091983.","article-title":"Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I","volume":"207","author":"Puel","year":"2010","journal-title":"J Exp Med"},{"key":"B59","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1084\/jem.20091669","article-title":"Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines","volume":"207","author":"Kisand","year":"2010","journal-title":"J Exp Med."},{"key":"B60","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.oraloncology.2006.07.005","article-title":"Oral and oesophageal squamous cell carcinoma \u2013 A complication or component of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED, APS-I)","volume":"43","author":"Rautemaa","year":"2007","journal-title":"Oral Oncol."},{"key":"B61","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1016\/j.jaad.2009.06.061","article-title":"Oral mucous squamous cell carcinoma\u2014an anticipated consequence of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)","volume":"62","author":"B\u00f6ckle","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"B62","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1177\/2050640616684404","article-title":"Oesophageal candidiasis and squamous cell cancer in patients with gain-of-function STAT1 gene mutation","volume":"5","author":"Koo","year":"2017","journal-title":"United Eur Gastroenterol J"},{"key":"B63","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1001\/archderm.1975.01630170083013","article-title":"Candidiasis and multiple endocrinopathy: with oral squamous cell carcinoma complications","volume":"111","author":"Richman","year":"1975","journal-title":"Arch Dermatol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"401","DOI":"10.3322\/caac.21293","article-title":"Oral cavity and oropharyngeal squamous cell carcinoma\u2014an update","volume":"65","author":"Chi","year":"2015","journal-title":"CA Cancer J Clin"},{"key":"B65","doi-asserted-by":"publisher","first-page":"e36","DOI":"10.1016\/j.oooo.2012.04.013","article-title":"Multiple oral squamous cell carcinomas associated with autoimmune polyendocrinopathy\u2013candidiasis\u2013ectodermal dystrophy","volume":"114","author":"Shephard","year":"2012","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"B66","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1600-0714.1983.tb00312.x","article-title":"Etiology of oral squamous cell carcinoma","volume":"12","author":"Binnie","year":"1983","journal-title":"J Oral Pathol"},{"key":"B67","doi-asserted-by":"publisher","first-page":"60","DOI":"10.4103\/0019-509X.25886","article-title":"Oral squamous cell carcinoma: etiology, pathogenesis and prognostic value of genomic alterations","volume":"43","author":"Mehrotra","year":"2006","journal-title":"Indian J Cancer"},{"key":"B68","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1038\/s41564-017-0059-5","article-title":"EphA2 is an epithelial cell pattern recognition receptor for fungal \u03b2-glucans","volume":"3","author":"Swidergall","year":"2018","journal-title":"Nat Microbiol."},{"key":"B69","doi-asserted-by":"publisher","first-page":"14194","DOI":"10.1073\/pnas.1117676109","article-title":"EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection","volume":"109","author":"Zhu","year":"2012","journal-title":"Proc Natl Acad Sci USA"},{"key":"B70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/AAC.39.1.1","article-title":"Resistance of Candida species to fluconazole","volume":"39","author":"Rex","year":"1995","journal-title":"Antimicrob Agents Chemother."},{"key":"B71","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/00002030-199603000-00004","article-title":"Oropharyngeal yeast flora and fluconazole resistance in HIV-infected patients receiving long-term continuous versus intermittent fluconazole therapy","volume":"10","author":"Heald","year":"1996","journal-title":"AIDS"},{"key":"B72","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1080\/00365540802275853","article-title":"Reduction of fluconazole susceptibility of Candida albicans in APECED patients due to long-term use of ketoconazole and miconazole","volume":"40","author":"Rautemaa","year":"2008","journal-title":"Scand J Infect Dis"},{"key":"B73","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.diagmicrobio.2008.05.007","article-title":"Activity of amphotericin B, anidulafungin, caspofungin, micafungin, posaconazole, and voriconazole against Candida albicans with decreased susceptibility to fluconazole from APECED patients on long-term azole treatment of chronic mucocutaneous candidiasis","volume":"62","author":"Rautemaa","year":"2008","journal-title":"Diagn Microbiol Infect Dis."},{"key":"B74","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1128\/JCM.00026-11","article-title":"Microbiological screening of irish patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy reveals persistence of Candida albicans Strains, gradual reduction in susceptibility to azoles, and incidences of clinical signs of oral candidiasis without culture evidence","volume":"49","author":"McManus","year":"2011","journal-title":"J Clin Microbiol"},{"key":"B75","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/j.lpm.2017.05.029","article-title":"Polyendocrinopathies auto-immunes de type 1 et pathologies buccales","volume":"46","author":"Proust-Lemoine","year":"2017","journal-title":"Presse M\u00e9d"},{"key":"B76","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1093\/jac\/dkm299","article-title":"Decreased susceptibility of Candida albicans to azole antifungals: a complication of long-term treatment in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients","volume":"60","author":"Rautemaa","year":"2007","journal-title":"J Antimicrob Chemother."},{"key":"B77","doi-asserted-by":"publisher","first-page":"2505","DOI":"10.1093\/jac\/dkq354","article-title":"Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy\u2013candidiasis\u2013ectodermal dystrophy (APECED) patients","volume":"65","author":"Siikala","year":"2010","journal-title":"J Antimicrob Chemother."},{"key":"B78","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1093\/intimm\/dxx039","article-title":"IVIG-mediated effector functions in autoimmune and inflammatory diseases","volume":"29","author":"Galeotti","year":"2017","journal-title":"Int Immunol."},{"key":"B79","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.tips.2004.04.002","article-title":"Intravenous immunoglobulin for infectious diseases: back to the pre-antibiotic and passive prophylaxis era?","volume":"25","author":"Bayry","year":"2004","journal-title":"Trends Pharmacol Sci."},{"key":"B80","doi-asserted-by":"publisher","first-page":"1036.e1","DOI":"10.1016\/j.amjmed.2012.01.023","article-title":"Intravenous immunoglobulin (IVIg) for refractory and difficult-to-treat infections","volume":"125","author":"Ferrara","year":"2012","journal-title":"Am J Med."},{"key":"B81","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1016\/j.jaci.2010.12.1102","article-title":"Inhibition of differentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin","volume":"127","author":"Maddur","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"B82","doi-asserted-by":"publisher","first-page":"275","DOI":"10.3389\/fimmu.2017.00275","article-title":"Monomeric immunoglobulin A from plasma inhibits human Th17 responses in vitro independent of Fc\u03b1RI and DC-SIGN","volume":"8","author":"Saha","year":"2017","journal-title":"Front Immunol."},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201847774.","article-title":"Intravenous immunoglobulin protects from experimental allergic bronchopulmonary aspergillosis via a sialylation-dependent mechanism","author":"Bozza","year":"2018","journal-title":"Eur J Immunol"},{"key":"B84","doi-asserted-by":"publisher","first-page":"e289","DOI":"10.1371\/journal.pmed.0030289","article-title":"Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1","volume":"3","author":"Meager","year":"2006","journal-title":"PLoS Med."},{"key":"B85","doi-asserted-by":"publisher","first-page":"4389","DOI":"10.1210\/jc.2008-0935","article-title":"Autoantibodies against type I interferons as an additional diagnostic criterion for autoimmune polyendocrine syndrome type I","volume":"93","author":"Meloni","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"B86","doi-asserted-by":"publisher","first-page":"1517","DOI":"10.1002\/eji.201041253","article-title":"Mucocutaneous candidiasis and autoimmunity against cytokines in APECED and thymoma patients: clinical and pathogenetic implications","volume":"41","author":"Kisand","year":"2011","journal-title":"Eur J Immunol."},{"key":"B87","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s10875-014-9987-5","article-title":"Autoantibodies to IL-17A may be Correlated with the Severity of Mucocutaneous Candidiasis in APECED Patients","volume":"34","author":"Sarkadi","year":"2014","journal-title":"J Clin Immunol."},{"key":"B88","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1002\/eji.201747209","article-title":"IL-22 neutralizing autoantibodies impair fungal clearance in murine oropharyngeal candidiasis model","volume":"48","author":"Bichele","year":"2018","journal-title":"Eur J Immunol"},{"key":"B89","doi-asserted-by":"publisher","first-page":"2657","DOI":"10.1182\/blood-2008-03-144634","article-title":"Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes","volume":"112","author":"Kisand","year":"2008","journal-title":"Blood"},{"key":"B90","doi-asserted-by":"publisher","first-page":"1006","DOI":"10.1016\/j.jaci.2010.08.027","article-title":"Impaired TH17 responses in patients with chronic mucocutaneous candidiasis with and without autoimmune polyendocrinopathy\u2013candidiasis\u2013ectodermal dystrophy","volume":"126","author":"Ng","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"B91","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1002\/eji.200939883","article-title":"Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model","volume":"41","author":"Ahlgren","year":"2011","journal-title":"Eur J Immunol."},{"key":"B92","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1007\/s10875-015-0176-y","article-title":"Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy","volume":"35","author":"Kisand","year":"2015","journal-title":"J Clin Immunol."},{"key":"B93","doi-asserted-by":"publisher","first-page":"556","DOI":"10.3109\/08916934.2014.929666.","article-title":"In vivo analysis of helper T cell responses in patients with autoimmune polyendocrinopathy \u2013 candidiasis \u2013 ectodermal dystrophy provides evidence in support of an IL-22 defect","volume":"47","author":"Laakso","year":"2014","journal-title":"Autoimmunity"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2018.02570\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T09:24:54Z","timestamp":1542619494000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2018.02570\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,19]]},"references-count":93,"alternative-id":["10.3389\/fimmu.2018.02570"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2018.02570","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,19]]},"article-number":"2570"}}