{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T07:19:26Z","timestamp":1790061566608,"version":"4.0.1"},"reference-count":12,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T00:00:00Z","timestamp":1542672000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2018.02702","type":"journal-article","created":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T04:18:25Z","timestamp":1542687505000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["IL-9 Integrates the Host-Candida Cross-Talk in Vulvovaginal Candidiasis to Balance Inflammation and Tolerance"],"prefix":"10.3389","volume":"9","author":[{"given":"Giorgia","family":"Renga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Borghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasileios","family":"Oikonomou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Mosci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bartoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Christophe","family":"Renauld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigina","family":"Romani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Costantini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,11,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1111\/j.1749-6632.1988.tb40450.x","article-title":"Pathogenesis and epidemiology of vulvovaginal candidiasis","volume":"544","author":"Sobel","year":"1988","journal-title":"Ann N Y Acad Sci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e00684","DOI":"10.1128\/IAI.00684-17","article-title":"Novel mechanism behind the immunopathogenesis of vulvovaginal candidiasis: \u201cneutrophil anergy\u201d","volume":"86","author":"Yano","year":"2018","journal-title":"Infect Immun."},{"key":"B3","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1097\/00007435-200004000-00009","article-title":"Candida vaginitis: self-reported incidence and associated costs","volume":"27","author":"Foxman","year":"2000","journal-title":"Sex Transm Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1767","DOI":"10.1016\/j.celrep.2018.04.034","article-title":"IL-9 and mast cells are key players of Candida albicans commensalism and pathogenesis in the gut","volume":"23","author":"Renga","year":"2018","journal-title":"Cell Rep."},{"key":"B5","doi-asserted-by":"publisher","first-page":"14017","DOI":"10.1038\/ncomms14017","article-title":"A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis","volume":"8","author":"Moretti","year":"2017","journal-title":"Nat Commun."},{"key":"B6","doi-asserted-by":"publisher","first-page":"753","DOI":"10.2217\/WHE.10.57","article-title":"Celiac disease: an underappreciated issue in women's health","volume":"6","author":"Shah","year":"2010","journal-title":"Womens Health (Lond)."},{"key":"B7","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1016\/j.chom.2015.07.004","article-title":"Pathogenic NLRP3 inflammasome activity during Candida infection is negatively regulated by IL-22 via activation of NLRC4 and IL-1Ra","volume":"18","author":"Borghi","year":"2015","journal-title":"Cell Host Microbe"},{"key":"B8","doi-asserted-by":"publisher","first-page":"8138","DOI":"10.1073\/pnas.0305683101","article-title":"Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets","volume":"101","author":"Maedler","year":"2004","journal-title":"Proc Natl Acad Sci USA."},{"key":"B9","doi-asserted-by":"publisher","first-page":"219ra218","DOI":"10.1126\/scitranslmed.3007828","article-title":"Human TH9 cells are skin-tropic and have autocrine and paracrine proinflammatory capacity","volume":"6","author":"Schlapbach","year":"2014","journal-title":"Sci Transl Med."},{"key":"B10","first-page":"233","article-title":"MEDI-528, an anti-IL-9 humanized antibody for the treatment of asthma","volume":"12","author":"Antoniu","year":"2010","journal-title":"Curr Opin Mol Ther."},{"key":"B11","doi-asserted-by":"publisher","first-page":"e1006688","DOI":"10.1371\/journal.ppat.1006688","article-title":"Sex differences shape the response to infectious diseases","volume":"13","author":"Ingersoll","year":"2017","journal-title":"PLoS Pathog."},{"key":"B12","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1093\/humupd\/dmi008","article-title":"Sex hormones and the immune response in humans","volume":"11","author":"Bouman","year":"2005","journal-title":"Hum Reprod Update"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2018.02702\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T04:18:27Z","timestamp":1542687507000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2018.02702\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,20]]},"references-count":12,"alternative-id":["10.3389\/fimmu.2018.02702"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2018.02702","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,20]]},"article-number":"2702"}}