{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:23:11Z","timestamp":1790828591901,"version":"4.1.0"},"reference-count":79,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T00:00:00Z","timestamp":1561075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2019.01303","type":"journal-article","created":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T14:30:26Z","timestamp":1561127426000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":55,"title":["Pruritus in Autoimmune and Inflammatory Dermatoses"],"prefix":"10.3389","volume":"10","author":[{"given":"Claudia","family":"Zeidler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel Pedro","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavien","family":"Huet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Misery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin","family":"Steinbrink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"St\u00e4nder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,6,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1159\/000131754","article-title":"Skin involvement in systemic autoimmune diseases","volume":"10","author":"Rashtak","year":"2008","journal-title":"Curr Dir Autoimmun"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.1038\/jid.2013.446","article-title":"The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions","volume":"134","author":"Hay","year":"2014","journal-title":"J Invest Dermatol"},{"key":"B3","doi-asserted-by":"publisher","first-page":"289","DOI":"10.2340\/00015555-1933","article-title":"Cutaneous sensory function is not related to depression and anxiety in patients with chronic pruritus with dysesthetic subqualities","volume":"95","author":"Schneider","year":"2015","journal-title":"Acta Derm Venereol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1007\/s00403-019-01890-4","article-title":"Atopic dermatitis and autoimmunity: the occurrence of autoantibodies and their association with disease severity","volume":"311","author":"Holmes","year":"2019","journal-title":"Arch Dermatol Res"},{"key":"B5","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.cytogfr.2019.01.001","article-title":"Emerging role of immune cell network in autoimmune skin disorders: an update on pemphigus, vitiligo and psoriasis","volume":"45","author":"Das","year":"2019","journal-title":"Cytokine Growth Factor Rev"},{"key":"B6","doi-asserted-by":"publisher","first-page":"689","DOI":"10.3389\/fimmu.2018.00689","article-title":"Immunoglobulin E-Mediated Autoimmunity","volume":"9","author":"Maurer","year":"2018","journal-title":"Front Immunol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"2746","DOI":"10.3389\/fimmu.2018.02746","article-title":"Psoriasis: Classical vs. paradoxical. The yin-yang of TNF and type i interferon","volume":"9","author":"Mylonas","year":"2018","journal-title":"Front Immunol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1001\/jamapediatrics.2017.0556","article-title":"Phenotypes of atopic dermatitis depending on the timing of onset and progression in childhood","volume":"171","author":"Roduit","year":"2017","journal-title":"JAMA Pediatr"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/S0140-6736(15)00149-X","article-title":"Atopic dermatitis","volume":"387","author":"Weidinger","year":"2016","journal-title":"Lancet"},{"key":"B10","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1111\/j.1365-2133.2008.08941.x","article-title":"Itch characteristics in atopic dermatitis: results of a web-based questionnaire","volume":"160","author":"Dawn","year":"2009","journal-title":"Br J Dermatol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.jdermsci.2017.11.015","article-title":"Reconstructed human epidermis for in vitro studies on atopic dermatitis: a review","volume":"89","author":"Huet","year":"2018","journal-title":"J Dermatol Sci"},{"key":"B12","doi-asserted-by":"publisher","first-page":"279","DOI":"10.2340\/00015555-3053","article-title":"Characteristics of pruritus in relation to self-assessed severity of atopic dermatitis","volume":"99","author":"Huet","year":"2019","journal-title":"Acta Derm Venereol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jid.2016.07.012","article-title":"The burden of atopic dermatitis: summary of a report for the national eczema association","volume":"137","author":"Drucker","year":"2017","journal-title":"J Invest Dermatol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"455","DOI":"10.2340\/00015555-1360","article-title":"Relieving the pruritus of atopic dermatitis: a meta-analysis","volume":"92","author":"Sher","year":"2012","journal-title":"Acta Derm Venereol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"808","DOI":"10.3349\/ymj.2010.51.6.808","article-title":"Protease and protease-activated receptor-2 signaling in the pathogenesis of atopic dermatitis","volume":"51","author":"Lee","year":"2010","journal-title":"Yonsei Med J"},{"key":"B16","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.cell.2013.08.057","article-title":"The epithelial cell-derived atopic dermatitis cytokine TSLP activates neurons to induce itch","volume":"155","author":"Wilson","year":"2013","journal-title":"Cell"},{"key":"B17","doi-asserted-by":"publisher","first-page":"816","DOI":"10.1684\/ejd.2011.1470","article-title":"Effects of cyclosporine on pruritus and serum IL-31 levels in patients with atopic dermatitis","volume":"21","author":"Otsuka","year":"2011","journal-title":"Eur J Dermatol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"124","DOI":"10.11817\/j.issn.1672-7347.2018.02.003","article-title":"Serum interleukin-31 level and pruritus in atopic dermatitis: a meta-analysis","volume":"43","author":"Lu","year":"2018","journal-title":"Zhong Nan Da Xue Xue Bao Yi Xue Ban."},{"key":"B19","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.jaci.2005.10.033","article-title":"IL-31: A new link between T cells and pruritus in atopic skin inflammation","volume":"117","author":"Sonkoly","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1038\/ni.3614","article-title":"The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin","volume":"18","author":"Hidaka","year":"2017","journal-title":"Nat Immunol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1111\/1346-8138.12317","article-title":"Itch and nerve fibers with special reference to atopic dermatitis: therapeutic implications","volume":"41","author":"Tominaga","year":"2014","journal-title":"J Dermatol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1016\/j.jid.2018.11.006","article-title":"3-dimensional optical clearing and imaging of pruritic atopic dermatitis and psoriasis skin reveals downregulation of epidermal innervation","volume":"139","author":"Tan","year":"2019","journal-title":"J Invest Dermatol"},{"key":"B23","doi-asserted-by":"publisher","first-page":"2012","DOI":"10.1016\/S0140-6736(00)05114-X","article-title":"Narrow-band ultraviolet B and broad-band ultraviolet A phototherapy in adult atopic eczema: a randomised controlled trial","volume":"357","author":"Reynolds","year":"2001","journal-title":"Lancet"},{"key":"B24","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1111\/j.1365-2222.2004.1907.x","article-title":"Comparing tacrolimus ointment and oral cyclosporine in adult patients affected by atopic dermatitis: a randomized study","volume":"34","author":"Pacor","year":"2004","journal-title":"Clin Exp Allergy"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1016\/j.jid.2018.10.043","article-title":"A phase 2 randomized trial of apremilast in patients with atopic dermatitis","volume":"139","author":"Simpson","year":"2018","journal-title":"J Invest Dermatol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1016\/j.jaci.2018.03.018","article-title":"Nemolizumab in patients with moderate-to-severe atopic dermatitis: randomized, phase II, long-term extension study","volume":"142","author":"Kabashima","year":"2018","journal-title":"J Allergy Clin Immunol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1016\/j.jaad.2018.11.059","article-title":"Tezepelumab, an anti-thymic stromal lymphopoietin monoclonal antibody, in the treatment of moderate to severe atopic dermatitis: a randomized phase 2a clinical trial","volume":"80","author":"Simpson","year":"2018","journal-title":"J Am Acad Dermatol"},{"key":"B28","unstructured":"Efficacy and safety of crisaborole ointment, a novel, nonsteroidal phosphodiesterase 4 (PDE4) inhibitor for the topical treatment of atopic dermatitis (AD) in children and adults494503\n            PallerAS\n            TomWL\n            LebwohlMG\n            BlumenthalRL\n            BoguniewiczM\n            CallRS\n          27417017J Am Acad Dermatol752016"},{"key":"B29","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.coph.2018.12.003","article-title":"Current pharmaceutical developments in atopic dermatitis","volume":"46","author":"Misery","year":"2019","journal-title":"Curr Opin Pharmacol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1046\/j.1365-2133.2000.03829.x","article-title":"The prevalence and clinical characteristics of pruritus among patients with extensive psoriasis","volume":"143","author":"Yosipovitch","year":"2000","journal-title":"Br J Dermatol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"573","DOI":"10.2340\/00015555-1599","article-title":"Itch characteristics in five dermatoses: non-atopic eczema, atopic dermatitis, urticaria, psoriasis and scabies","volume":"93","author":"Brenaut","year":"2013","journal-title":"Acta Derm Venereol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"439","DOI":"10.2340\/00015555-1975","article-title":"Pruritus in psoriasis: a study of personality traits, depression and anxiety","volume":"95","author":"Remrod","year":"2015","journal-title":"Acta Derm Venereol"},{"key":"B33","doi-asserted-by":"publisher","first-page":"429","DOI":"10.2340\/00015555-3147","article-title":"Itch in Psoriasis: a new look at well-known subject","volume":"99","author":"Reszke","year":"2019","journal-title":"Acta Derm Venereol"},{"key":"B34","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1016\/j.jaad.2013.12.018","article-title":"Patient perspectives in the management of psoriasis: results from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis Survey","volume":"70","author":"Lebwohl","year":"2014","journal-title":"J Am Acad Dermatol"},{"key":"B35","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1016\/j.jid.2017.12.029","article-title":"The Genetics of chronic itch: gene expression in the skin of patients with atopic dermatitis and psoriasis with severe itch","volume":"138","author":"Nattkemper","year":"2018","journal-title":"J Invest Dermatol"},{"key":"B36","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.jid.2017.05.039","article-title":"Efficacy of systemic treatments of psoriasis on pruritus: a systemic literature review and meta-analysis","volume":"138","author":"Therene","year":"2018","journal-title":"J Invest Dermatol"},{"key":"B37","doi-asserted-by":"publisher","first-page":"1014","DOI":"10.1111\/bjd.15666","article-title":"Comparison of ixekizumab with ustekinumab in moderate-to-severe psoriasis: 24-week results from IXORA-S, a phase III study","volume":"177","author":"Reich","year":"2017","journal-title":"Br J Dermatol"},{"key":"B38","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1111\/jdv.14910","article-title":"Patient-reported symptoms and signs of moderate-to-severe psoriasis treated with guselkumab or adalimumab: results from the randomized VOYAGE 1 trial","volume":"32","author":"Papp","year":"2018","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"B39","doi-asserted-by":"publisher","first-page":"542","DOI":"10.2340\/00015555-2047","article-title":"Topical TrkA kinase inhibitor CT327 is an effective, novel therapy for the treatment of pruritus due to psoriasis: results from experimental studies, and efficacy and safety of CT327 in a phase 2b clinical trial in patients with psoriasis","volume":"95","author":"Roblin","year":"2015","journal-title":"Acta Derm Venereol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1111\/ddg.13637","article-title":"Diagnosis of autoimmune bullous diseases","volume":"16","author":"van","year":"2018","journal-title":"J Dtsch Dermatol Ges"},{"key":"B41","doi-asserted-by":"publisher","first-page":"201","DOI":"10.3389\/fmed.2018.00201","article-title":"The role of eosinophils in bullous pemphigoid: a developing model of eosinophil pathogenicity in mucocutaneous disease","volume":"5","author":"Amber","year":"2018","journal-title":"Front Med."},{"key":"B42","doi-asserted-by":"publisher","first-page":"766","DOI":"10.2340\/00015555-2951","article-title":"Eosinophils are a major source of interleukin-31 in bullous pemphigoid","volume":"98","author":"Rudrich","year":"2018","journal-title":"Acta Derm Venereol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/j.jaci.2016.02.020","article-title":"The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves","volume":"138","author":"Feld","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13705","article-title":"Possible roles of basophils in chronic itch","author":"Hashimoto","year":"2018","journal-title":"Exp Dermatol"},{"key":"B45","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1046\/j.1523-1747.2003.12146.x","article-title":"Identification of a potential effector function for IgE autoantibodies in the organ-specific autoimmune disease bullous pemphigoid","volume":"120","author":"Dimson","year":"2003","journal-title":"J Invest Dermatol"},{"key":"B46","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1007\/s00105-011-2319-2","article-title":"Chronic pruritus in autoimmune dermatoses: results of a comparative survey","volume":"63","author":"Schroder","year":"2012","journal-title":"Hautarzt"},{"key":"B47","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/S0140-6736(12)61140-4","article-title":"Pemphigoid diseases","volume":"381","author":"Schmidt","year":"2013","journal-title":"Lancet"},{"key":"B48","first-page":"508","article-title":"Bullous pemphigoid presenting as generalized pruritus: observations in six patients","volume":"37","author":"Alonso-Llamazares","year":"1998","journal-title":"Int J Dermatol"},{"key":"B49","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1001\/jamadermatol.2013.756","article-title":"Bullous pemphigoid as pruritus in the elderly: a common presentation","volume":"149","author":"Bakker","year":"2013","journal-title":"JAMA Dermatol"},{"key":"B50","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1111\/bjd.12936","article-title":"BP180- and BP230-specific IgG autoantibodies in pruritic disorders of the elderly: a preclinical stage of bullous pemphigoid?","volume":"171","author":"Schmidt","year":"2014","journal-title":"Br J Dermatol"},{"key":"B51","doi-asserted-by":"publisher","first-page":"2443","DOI":"10.1001\/jama.2013.282023","article-title":"Pruritus in the older patient: a clinical review","volume":"310","author":"Berger","year":"2013","journal-title":"JAMA"},{"key":"B52","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1111\/bjd.13717","article-title":"Management of bullous pemphigoid: the european dermatology forum consensus in collaboration with the European Academy of Dermatology and Venereology","volume":"172","author":"Feliciani","year":"2015","journal-title":"Br J Dermatol"},{"key":"B53","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1111\/j.1346-8138.2011.01382.x","article-title":"Quality of life and psychological status of patients with pemphigus vulgaris using Dermatology Life Quality Index and General Health Questionnaires","volume":"39","author":"Ghodsi","year":"2012","journal-title":"J Dermatol"},{"key":"B54","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1111\/vde.12731","article-title":"Clinicopathological findings and clinical outcomes in 49 cases of feline pemphigus foliaceus examined in Northern California, USA (1987-2017)","volume":"30","author":"Jordan","year":"2019","journal-title":"Vet Dermatol"},{"key":"B55","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1111\/bjd.14647","article-title":"Valuation of pemphigus vulgaris and pemphigus foliaceus health states: a convenience sample experiment","volume":"175","author":"Rencz","year":"2016","journal-title":"Br J Dermatol"},{"key":"B56","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1016\/S0738-081X(00)00184-X","article-title":"Dermatitis herpetiformis","volume":"19","author":"Reunala","year":"2001","journal-title":"Clin Dermatol"},{"key":"B57","doi-asserted-by":"publisher","first-page":"5965492","DOI":"10.1155\/2017\/5965492","article-title":"The role of intereukin-31 in pathogenesis of itch and its intensity in a course of bullous pemphigoid and dermatitis herpetiformis","volume":"2017","author":"Kulczycka-Siennicka","year":"2017","journal-title":"Biomed Res Int"},{"key":"B58","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.jaci.2008.05.047","article-title":"Correlation of IL-31 serum levels with severity of atopic dermatitis","volume":"122","author":"Raap","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1007\/s00403-012-1293-6","article-title":"Narrow band ultraviolet B irradiations cause alteration in interleukin-31 serum level in psoriatic patients","volume":"305","author":"Narbutt","year":"2013","journal-title":"Arch Dermatol Res"},{"key":"B60","doi-asserted-by":"publisher","first-page":"735","DOI":"10.2340\/00015555-2980","article-title":"Clinical characteristics of pruritus in systemic sclerosis vary according to the autoimmune subtype","volume":"98","author":"Gourier","year":"2018","journal-title":"Acta Derm Venereol"},{"key":"B61","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1111\/bjd.14998","article-title":"Itch and systemic sclerosis: frequency, clinical characteristics and consequences","volume":"176","author":"Therene","year":"2017","journal-title":"Br J Dermatol"},{"key":"B62","doi-asserted-by":"publisher","first-page":"86","DOI":"10.2174\/1573397112666160907105434","article-title":"Localized scleroderma: a clinical review","volume":"13","author":"Tratenberg","year":"2017","journal-title":"Curr Rheumatol Rev"},{"key":"B63","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1111\/bjd.13572","article-title":"Health-related quality of life in morphoea","volume":"172","author":"Klimas","year":"2015","journal-title":"Br J Dermatol"},{"key":"B64","doi-asserted-by":"publisher","first-page":"3491798","DOI":"10.1155\/2018\/3491798","article-title":"Prevalence of pruritus in cutaneous lupus erythematosus: brief report of a multicenter, multinational cross-sectional study","volume":"2018","author":"Samotij","year":"2018","journal-title":"Biomed Res Int"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1097\/00124743-900000000-99059","article-title":"Refractory cutaneous dermatomyositis with severe scalp pruritus responsive to apremilast","author":"Charlton","year":"2019","journal-title":"J Clin Rheumatol"},{"key":"B66","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.det.2018.02.013","article-title":"Pruritus in autoimmune connective tissue diseases","volume":"36","author":"Smith","year":"2018","journal-title":"Dermatol Clin"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14252","article-title":"Itching, chloroquine, and malaria: a review of recent molecular and neuroscience advances and their contribution to mechanistic understanding and therapeutics of chronic non-histaminergic pruritus","author":"Ajayi","year":"2018","journal-title":"Int J Dermatol"},{"key":"B68","first-page":"179","article-title":"One year in review 2017: primary Sjogren's syndrome","volume":"35","author":"Ferro","year":"2017","journal-title":"Clin Exp Rheumatol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"385","DOI":"10.2340\/00015555-2524","article-title":"Chronic pruritus in primary sjogren's syndrome: characteristics and effect on quality of life","volume":"97","author":"Valdes-Rodriguez","year":"2017","journal-title":"Acta Derm Venereol"},{"key":"B70","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1046\/j.1365-2133.1997.18091892.x","article-title":"Effects of xerosis and ageing on epidermal proliferation and differentiation","volume":"137","author":"Engelke","year":"1997","journal-title":"Br J Dermatol"},{"key":"B71","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/s12016-017-8652-1","article-title":"Cutaneous manifestations of dermatomyositis: a comprehensive review","volume":"53","author":"Mainetti","year":"2017","journal-title":"Clin Rev Allergy Immunol"},{"key":"B72","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.jaad.2010.10.016","article-title":"Quality of life in dermatomyositis","volume":"65","author":"Goreshi","year":"2011","journal-title":"J Am Acad Dermatol"},{"key":"B73","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1111\/bjd.14678","article-title":"Small-fibre neuropathy in a patient with dermatomyositis and severe scalp pruritus","volume":"176","author":"Hurliman","year":"2017","journal-title":"Br J Dermatol"},{"key":"B74","doi-asserted-by":"publisher","first-page":"5617838","DOI":"10.1155\/2017\/5617838","article-title":"Prevalence and clinical characteristics of itch in vitiligo and its clinical significance","volume":"2017","author":"Vachiramon","year":"2017","journal-title":"Biomed Res Int"},{"key":"B75","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1186\/gm199","article-title":"The genetics of generalized vitiligo: autoimmune pathways and an inverse relationship with malignant melanoma","volume":"2","author":"Spritz","year":"2010","journal-title":"Genome Med"},{"key":"B76","doi-asserted-by":"publisher","first-page":"421","DOI":"10.4103\/0019-5154.119947","article-title":"Role of histamine as a toxic mediator in the pathogenesis of vitiligo","volume":"58","author":"Panja","year":"2013","journal-title":"Ind J Dermatol"},{"key":"B77","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.jaad.2009.03.022","article-title":"The burden of vitiligo: patient characteristics associated with quality of life","volume":"61","author":"Linthorst","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"B78","doi-asserted-by":"publisher","first-page":"142","DOI":"10.4103\/0019-5154.152508","article-title":"Quality of life and psychological morbidity in vitiligo patients: a study in a teaching hospital from north-East India","volume":"60","author":"Sangma","year":"2015","journal-title":"Ind J Dermatol"},{"key":"B79","doi-asserted-by":"publisher","first-page":"469","DOI":"10.2340\/00015555-3164","article-title":"European S2k guideline on chronic pruritus","volume":"99","author":"Weisshaar","year":"2019","journal-title":"Acta Derm Venereol"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01303\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T14:30:30Z","timestamp":1561127430000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01303\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,21]]},"references-count":79,"alternative-id":["10.3389\/fimmu.2019.01303"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2019.01303","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,21]]},"article-number":"1303"}}