{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:30:48Z","timestamp":1762867848338,"version":"3.41.2"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T00:00:00Z","timestamp":1561075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2019.01329","type":"journal-article","created":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T13:45:26Z","timestamp":1561124726000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["The Inhibition of Caspase-1- Does Not Revert Particulate Matter (PM)-Induced Lung Immunesuppression in Mice"],"prefix":"10.3389","volume":"10","author":[{"given":"Chiara","family":"Colarusso","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluigi","family":"De Falco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michela","family":"Terlizzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiorentina","family":"Roviezzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ida","family":"Cerqua","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariano","family":"Sirignano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Cirino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita P.","family":"Aquino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aldo","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"D'Anna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosalinda","family":"Sorrentino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2019,6,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"802","DOI":"10.3109\/08958378.2013.850127","article-title":"Particulate matter beyond mass: recent health evidence on the role of fractions, chemical constituents and sources of emission","volume":"25","author":"Cassee","year":"2013","journal-title":"Inhal Toxicol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.atmosenv.2012.07.009","article-title":"Elemental carbon as an indicator for evaluating the impact of traffic measures on air quality and health","volume":"61","author":"Keuken","year":"2012","journal-title":"Atmos Environ."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2224","DOI":"10.1016\/S0140-6736(12)61766-8","article-title":"A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990\u20132010: a systematic analysis for the Global Burden of Disease Study 2010","volume":"380","author":"Lim","year":"2012","journal-title":"Lancet."},{"key":"B4","first-page":"809","article-title":"Air pollution ultrafine particles: toxicity beyond the lung","volume":"14","author":"Terzano","year":"2010","journal-title":"Eur Rev Med Pharmacol Sci."},{"key":"B5","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.atmosenv.2012.06.039","article-title":"Size source and chemical composition as determinants of toxicity attributable to ambient particulate matter","volume":"60","author":"Kelly","year":"2012","journal-title":"Atmos Environ."},{"key":"B6","doi-asserted-by":"publisher","first-page":"43016","DOI":"10.1038\/srep43016","article-title":"Human peripheral blood mononuclear cells (PBMCs) from smokers release higher levels of IL-1-like cytokines after exposure to combustion-generated ultrafine particles","volume":"7","author":"De Falco","year":"2017","journal-title":"Sci Rep."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1415","DOI":"10.3389\/fimmu.2017.01415","article-title":"Chronic obstructive pulmonary disease-derived circulating cells release IL-18 and IL-33 under ultrafine particulate matter exposure in a caspase-1\/8-independent manner","volume":"8","author":"De Falco","year":"2017","journal-title":"Front Immunol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"24166","DOI":"10.1038\/srep24166","article-title":"The caspase-1 inhibitor AC-YVAD-CMK attenuates acute gastric injury in mice: involvement of silencing NLRP3 inflammasome activities","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci Rep"},{"key":"B9","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1165\/rcmb.2014-0207OC","article-title":"B cell depletion increases sphingosine-1-phosphate-dependent airway inflammation in mice","volume":"52","author":"Sorrentino","year":"2015","journal-title":"Am J Respir Cell Mol Biol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1093\/nsr\/nww064","article-title":"Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century","volume":"3","author":"Xia","year":"2016","journal-title":"Natl Sci Rev"},{"key":"B11","doi-asserted-by":"publisher","first-page":"2007","DOI":"10.5194\/acp-12-2007-2012","article-title":"Ionic and carbonaceous compositions of PM10, PM2.5 and PM1.0 at Gosan ABC Superstation and their ratios as source signature","volume":"12","author":"Lim","year":"2012","journal-title":"Chem Phys."},{"key":"B12","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.pharmthera.2014.02.002","article-title":"Inflammasome: cancer's friend or foe?","volume":"143","author":"Terlizzi","year":"2014","journal-title":"Pharmacol Ther."},{"key":"B13","doi-asserted-by":"publisher","first-page":"81813","DOI":"10.18632\/oncotarget.17850","article-title":"Role of the inflammasome in chronic obstructive pulmonary disease (COPD)","volume":"8","author":"Colarusso","year":"2017","journal-title":"Oncotarget."},{"key":"B14","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1182\/blood-2003-08-2729","article-title":"Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis","volume":"103","author":"Wilson","year":"2004","journal-title":"Blood."},{"key":"B15","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/j.1600-065X.2011.01015.x","article-title":"Dendritic cell control of tolerogenic responses","volume":"241","author":"Manicassamy","year":"2011","journal-title":"Immunol Rev."},{"key":"B16","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1111\/j.1476-5381.2009.00291.x","article-title":"Arginase: an emerging key player in the mammalian immune system","volume":"158","author":"Munder","year":"2009","journal-title":"Br J Pharmacol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3389\/fimmu.2017.00093","article-title":"Arginine metabolism in myeloid cells shapes innate and adaptive immunity","volume":"8","author":"Rodriguez","year":"2017","journal-title":"Front Immunol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"27158","DOI":"10.1074\/jbc.M115.682708","article-title":"Interleukin 10 (IL-10)-mediated Immunosuppression: March-i induction regulates antigen presentation by macrophages but not dendritic cells","volume":"290","author":"Mittal","year":"2015","journal-title":"J Biol Chem."},{"key":"B19","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1189\/jlb.0705358","article-title":"Interleukin-10 and the immune response against cancer: a counterpoint","volume":"78","author":"Mocellin","year":"2005","journal-title":"J Leukoc Biol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1038\/nri1936","article-title":"Cancer despite immunosurveillance: immunoselection and immunosubversion","volume":"6","author":"Zitvogel","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"3115","DOI":"10.1016\/j.ajpath.2015.07.009","article-title":"Human lung cancer-derived immunosuppressive plasmacytoid dendritic cells release IL-1\u03b1 in an AIM2 inflammasome-dependent manner","volume":"185","author":"Sorrentino","year":"2015","journal-title":"Am J Pathol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1136\/thoraxjnl-2015-207927","article-title":"Air pollution affects lung cancer survival","volume":"71","author":"Eckel","year":"2016","journal-title":"Thorax."},{"key":"B23","doi-asserted-by":"publisher","first-page":"399","DOI":"10.2147\/COPD.S22179","article-title":"Dose-response curve to salbutamol during acute and chronic treatment with formoterol in COPD.","volume":"6","author":"La Piana","year":"2011","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"B24","doi-asserted-by":"publisher","first-page":"670","DOI":"10.3389\/fimmu.2018.00670","article-title":"Activation of the absent in Melanoma 2 inflammasome in peripheral blood mononuclear cells from idiopathic pulmonary fibrosis patients leads to the release of pro-fibrotic mediators","volume":"9","author":"Terlizzi","year":"2018","journal-title":"Front Immunol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3389\/fphar.2019.00257","article-title":"AIM2 inflammasome activation leads to IL-1\u03b1 and TGF-\u03b2 release from exacerbated chronic obstructive pulmonary disease-derived peripheral blood mononuclear cells","volume":"10","author":"Colarusso","year":"2019","journal-title":"Front Pharmacol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"3917","DOI":"10.1111\/bph.13176","article-title":"Pharmacological inhibition of caspase-8 limits lung tumour outgrowth","volume":"172","author":"Terlizzi","year":"2015","journal-title":"Br J Pharmacol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"58181","DOI":"10.18632\/oncotarget.11276","article-title":"IL-1\u03b1 and IL-1\u03b2-producing macrophages populate lung tumor lesions in mice","volume":"7","author":"Terlizzi","year":"2016","journal-title":"Oncotarget."}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01329\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T13:45:28Z","timestamp":1561124728000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01329\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,21]]},"references-count":27,"alternative-id":["10.3389\/fimmu.2019.01329"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2019.01329","relation":{},"ISSN":["1664-3224"],"issn-type":[{"type":"electronic","value":"1664-3224"}],"subject":[],"published":{"date-parts":[[2019,6,21]]},"article-number":"1329"}}