{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:28:42Z","timestamp":1790670522923,"version":"4.1.0"},"reference-count":205,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,7,3]],"date-time":"2019-07-03T00:00:00Z","timestamp":1562112000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2019.01524","type":"journal-article","created":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T13:16:58Z","timestamp":1562246218000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":134,"title":["Pathogenic Fungal Infection in the Lung"],"prefix":"10.3389","volume":"10","author":[{"given":"Zhi","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gen","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangxun","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,7,3]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1128\/CMR.12.2.310","article-title":"Aspergillus fumigatus and aspergillosis","volume":"12","author":"Latge","year":"1999","journal-title":"Clin Microbiol Rev"},{"key":"B2","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1097\/01.mcp.0000219272.57933.01","article-title":"Fungal respiratory disease","volume":"12","author":"Yao","year":"2006","journal-title":"Curr Opin Pulm Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1111\/j.1749-6632.2012.06754.x","article-title":"Inflammation in aspergillosis: the good, the bad, and the therapeutic","volume":"1273","author":"Carvalho","year":"2012","journal-title":"Ann N Y Acad Sci"},{"key":"B4","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/j.idc.2006.07.001","article-title":"Cryptococcosis","volume":"20","author":"Chayakulkeeree","year":"2006","journal-title":"Infect Dis Clin North Am"},{"key":"B5","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1038\/nrmicro2522","article-title":"Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box","volume":"9","author":"Kronstad","year":"2011","journal-title":"Nat Rev Microbiol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1128\/CMR.8.4.515","article-title":"Cryptococcosis in the era of AIDS\u2212100 years after the discovery of Cryptococcus neoformans","volume":"8","author":"Mitchell","year":"1995","journal-title":"Clin Microbiol Rev"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1056\/NEJM200409163511222","article-title":"Pneumocystis pneumonia","volume":"351","author":"Udwadia","year":"2004","journal-title":"N Engl J Med"},{"key":"B8","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1093\/jac\/43.3.321","article-title":"Endemic mycoses: a treatment update","volume":"43","author":"Lortholary","year":"1999","journal-title":"J Antimicrob Chemother"},{"key":"B9","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1128\/CMR.8.1.146","article-title":"Endemic mycoses in AIDS: a clinical review","volume":"8","author":"Wheat","year":"1995","journal-title":"Clin Microbiol Rev"},{"key":"B10","doi-asserted-by":"publisher","first-page":"7406","DOI":"10.4049\/jimmunol.173.12.7406","article-title":"TLRs govern neutrophil activity in aspergillosis","volume":"173","author":"Bellocchio","year":"2004","journal-title":"J Immunol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.mpmed.2012.03.013","article-title":"Opportunistic and fungal infections of the lung","volume":"40","author":"Jos\u00e9","year":"2012","journal-title":"Medicine"},{"key":"B12","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1136\/bmj.2.5244.91","article-title":"Cryptococcal meningo-encephalitis","volume":"2","author":"McMath","year":"1961","journal-title":"Br Med J"},{"key":"B13","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1038\/ni.1863","article-title":"The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors","volume":"11","author":"Kawai","year":"2010","journal-title":"Nat Immunol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/j.cell.2010.01.022","article-title":"Pattern recognition receptors and inflammation","volume":"140","author":"Takeuchi","year":"2010","journal-title":"Cell"},{"key":"B15","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.3201\/eid1507.090043","article-title":"Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure","volume":"15","author":"Howard","year":"2009","journal-title":"Emerg Infect Dis"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1889","DOI":"10.1128\/AAC.02286-13","article-title":"Identification of a key lysine residue in heat shock protein 90 required for azole and echinocandin resistance in Aspergillus fumigatus","volume":"58","author":"Lamoth","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"B17","doi-asserted-by":"publisher","first-page":"193","DOI":"10.3314\/mmj.52.193","article-title":"The genus Aspergillus","volume":"52","author":"Yaguchi","year":"2011","journal-title":"Med Mycol J"},{"key":"B18","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1128\/IAI.71.2.891-903.2003","article-title":"Phagocytosis and intracellular fate of Aspergillus fumigatus conidia in alveolar macrophages","volume":"71","author":"Ibrahim-Granet","year":"2003","journal-title":"Infect Immun"},{"key":"B19","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1080\/mmy.40.5.455.464","article-title":"Molecular characterization of a cell wall-associated beta(1-3)endoglucanase of Aspergillus fumigatus","volume":"40","author":"Mouyna","year":"2002","journal-title":"Med Mycol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"2819","DOI":"10.1099\/00221287-148-9-2819","article-title":"Characterization of a cell-wall acid phosphatase (PhoAp) in Aspergillus fumigatus","volume":"148","author":"Bernard","year":"2002","journal-title":"Microbiology"},{"key":"B21","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/S0966-842X(01)02104-7","article-title":"The pathobiology of Aspergillus fumigatus","volume":"9","author":"Latge","year":"2001","journal-title":"Trends Microbiol"},{"key":"B22","doi-asserted-by":"crossref","first-page":"3476","DOI":"10.1128\/IAI.61.8.3476-3481.1993","article-title":"Differential host susceptibility to intracerebral infections with Candida albicans and Cryptococcus neoformans","volume":"61","author":"Blasi","year":"1993","journal-title":"Infect Immun"},{"key":"B23","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1172\/JCI114966","article-title":"Purification and characterization of a major human Pneumocystis carinii surface antigen","volume":"87","author":"Lundgren","year":"1991","journal-title":"J Clin Invest"},{"key":"B24","doi-asserted-by":"publisher","first-page":"4320","DOI":"10.1128\/IAI.00507-10","article-title":"Relationship of Pneumocystis jiroveci humoral immunity to prevention of colonization and chronic obstructive pulmonary disease in a primate model of HIV infection","volume":"78","author":"Kling","year":"2010","journal-title":"Infect Immun"},{"key":"B25","doi-asserted-by":"publisher","first-page":"e64","DOI":"10.1086\/591701","article-title":"Relationship of pneumocystis antibody response to severity of chronic obstructive pulmonary disease","volume":"47","author":"Morris","year":"2008","journal-title":"Clin Infect Dis"},{"key":"B26","doi-asserted-by":"publisher","first-page":"e367","DOI":"10.1016\/S1473-3099(17)30306-7","article-title":"Neglected endemic mycoses","volume":"17","author":"Queiroz-Telles","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"B27","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1016\/j.rmed.2012.02.004","article-title":"Endemic mycoses: overlooked causes of community acquired pneumonia","volume":"106","author":"Hage","year":"2012","journal-title":"Respir Med"},{"key":"B28","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1007\/s11908-013-0387-4","article-title":"Endemic mycoses in immunocompromised hosts","volume":"15","author":"Malcolm","year":"2013","journal-title":"Curr Infect Dis Rep"},{"key":"B29","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1093\/cid\/cir028","article-title":"Epidemiology, seasonality, and predictors of outcome of AIDS-associated Penicillium marneffei infection in Ho Chi Minh City, Viet Nam","volume":"52","author":"Le","year":"2011","journal-title":"Clin Infect Dis"},{"key":"B30","doi-asserted-by":"publisher","first-page":"676","DOI":"10.7326\/0003-4819-133-9-200011070-00009","article-title":"Comparison of oral fluconazole and itraconazole for progressive, nonmeningeal coccidioidomycosis","volume":"133","author":"Galgiani","year":"2000","journal-title":"Ann Intern Med"},{"key":"B31","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1128\/CMR.6.2.89","article-title":"Paracoccidioidomycosis: an update","volume":"6","author":"Brummer","year":"1993","journal-title":"Clin Microbiol Rev"},{"key":"B32","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/S1473-3099(11)70140-2","article-title":"Cryptococcus: from human pathogen to model yeast","volume":"11","author":"Boulware","year":"2011","journal-title":"Lancet Infect Dis"},{"key":"B33","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1590\/S0036-46652003000600001","article-title":"Cryptococcosis: a review of the Brazilian experience for the disease","volume":"45","author":"Pappalardo","year":"2003","journal-title":"Rev Inst Med Trop"},{"key":"B34","doi-asserted-by":"publisher","first-page":"S338","DOI":"10.1093\/clinids\/12.Supplement_3.S338","article-title":"Overview: treatment of cryptococcal meningitis","volume":"12","author":"Sugar","year":"1990","journal-title":"Rev Infect Dis"},{"key":"B35","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1097\/QAD.0b013e328322ffac","article-title":"Estimation of the current global burden of cryptococcal meningitis among persons living with HIV\/AIDS. AIDS","volume":"23","author":"Park","year":"2009"},{"key":"B36","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1128\/IAI.01065-08","article-title":"Evidence of a role for monocytes in dissemination and brain invasion by Cryptococcus neoformans","volume":"77","author":"Charlier","year":"2009","journal-title":"Infect Immun"},{"key":"B37","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1038\/nrmicro1952","article-title":"Mechanisms of microbial traversal of the blood-brain barrier","volume":"6","author":"Kim","year":"2008","journal-title":"Nat Rev Microbiol"},{"key":"B38","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1093\/clinids\/21.1.28","article-title":"Clinical and host differences between infections with the two varieties of Cryptococcus neoformans","volume":"21","author":"Speed","year":"1995","journal-title":"Clin Infect Dis"},{"key":"B39","first-page":"42","article-title":"Ecology of Cryptococcus neoformans","volume":"14","author":"Sorrell","year":"1997","journal-title":"Rev Iberoam Micol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"17258","DOI":"10.1073\/pnas.0402981101","article-title":"A rare genotype of Cryptococcus gattii caused the cryptococcosis outbreak on Vancouver Island (British Columbia, Canada)","volume":"101","author":"Kidd","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"B41","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1097\/QAD.0b013e32832be0fc","article-title":"High ongoing burden of cryptococcal disease in Africa despite antiretroviral roll out","volume":"23","author":"Jarvis","year":"2009","journal-title":"AIDS"},{"key":"B42","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1056\/NEJM198909213211205","article-title":"Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome","volume":"321","author":"Chuck","year":"1989","journal-title":"N Engl J Med"},{"key":"B43","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1093\/clinids\/21.3.628","article-title":"Pulmonary cryptococcosis: localized and disseminated infections in 27 patients with AIDS. Clin Infect Dis","volume":"21","author":"Meyohas","year":"1995"},{"key":"B44","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.diagmicrobio.2012.01.008","article-title":"Difference in Cryptococcus neoformans cellular and capsule size in sequential pulmonary and meningeal infection: a postmortem study","volume":"73","author":"Xie","year":"2012","journal-title":"Diagn Microbiol Infect Dis"},{"key":"B45","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1007\/s11046-011-9499-2","article-title":"Voriconazole, combined with amphotericin B, in the treatment for pulmonary cryptococcosis caused by C. neoformans (serotype A) in mice with severe combined immunodeficiency (SCID)","volume":"173","author":"Silva","year":"2012","journal-title":"Mycopathologia"},{"key":"B46","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.ijid.2004.12.004","article-title":"Cryptococcosis in human immunodeficiency virus-negative patients","volume":"10","author":"Kiertiburanakul","year":"2006","journal-title":"Int J Infect Dis"},{"key":"B47","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.prrv.2009.06.009","article-title":"Cryptococcosis in children","volume":"10","author":"Severo","year":"2009","journal-title":"Paediatr Respir Rev"},{"key":"B48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/jac\/28.suppl_B.1","article-title":"Epidemiology and pathogenesis of systemic fungal infections in the immunocompromised host","volume":"28","author":"Denning","year":"1991","journal-title":"J Antimicrob Chemother"},{"key":"B49","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1086\/339202","article-title":"Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients","volume":"34","author":"Marr","year":"2002","journal-title":"Clin Infect Dis"},{"key":"B50","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1093\/clinids\/13.3.487","article-title":"Candida and Aspergillus infections in immunocompromised patients: an overview","volume":"13","author":"Saral","year":"1991","journal-title":"Rev Infect Dis"},{"key":"B51","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1056\/NEJM200104053441415","article-title":"Invasive pulmonary aspergillosis associated with infliximab therapy","volume":"344","author":"Warris","year":"2001","journal-title":"N Engl J Med"},{"key":"B52","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1086\/313757","article-title":"Practice guidelines for the management of cryptococcal disease","volume":"30","author":"Saag","year":"2000","journal-title":"Clin Infect Dis"},{"key":"B53","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s101560050021","article-title":"Effect of sequential combination of amphotericin B and azole antifungal agents against Aspergillus fumigatus","volume":"5","author":"Maesaki","year":"1999","journal-title":"J Infect Chemother"},{"key":"B54","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1093\/jac\/dkh066","article-title":"A comparative study of the post-antifungal effect (PAFE) of amphotericin B, triazoles and echinocandins on Aspergillus fumigatus and Candida albicans","volume":"53","author":"Manavathu","year":"2004","journal-title":"J Antimicrob Chemother"},{"key":"B55","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/j.amjmed.2011.11.001","article-title":"Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment","volume":"125","author":"Pfaller","year":"2012","journal-title":"Am J Med"},{"key":"B56","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1038\/nature06246","article-title":"Recognition of microorganisms and activation of the immune response","volume":"449","author":"Medzhitov","year":"2007","journal-title":"Nature"},{"key":"B57","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1146\/annurev.micro.62.081307.162753","article-title":"How sweet it is! Cell wall biogenesis and polysaccharide capsule formation in Cryptococcus neoformans","volume":"63","author":"Doering","year":"2009","journal-title":"Annu Rev Microbiol"},{"key":"B58","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1146\/annurev.immunol.20.103001.114744","article-title":"Phagocytosis of microbes: complexity in action","volume":"20","author":"Underhill","year":"2002","journal-title":"Annu Rev Immunol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"3034","DOI":"10.1128\/IAI.71.6.3034-3042.2003","article-title":"Killing of Aspergillus fumigatus by alveolar macrophages is mediated by reactive oxidant intermediates","volume":"71","author":"Philippe","year":"2003","journal-title":"Infect Immun"},{"key":"B60","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/j.chom.2017.04.008","article-title":"Global reprogramming of host kinase signaling in response to fungal infection","volume":"21","author":"Pandey","year":"2017","journal-title":"Cell Host Microbe"},{"key":"B61","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1086\/600380","article-title":"Essential role for neutrophils but not alveolar macrophages at early time points following Aspergillus fumigatus infection","volume":"200","author":"Mircescu","year":"2009","journal-title":"J Infect Dis"},{"key":"B62","doi-asserted-by":"publisher","first-page":"1750","DOI":"10.1086\/314493","article-title":"Cytokine- and T helper-dependent lung mucosal immunity in mice with invasive pulmonary aspergillosis","volume":"178","author":"Cenci","year":"1998","journal-title":"J Infect Dis"},{"key":"B63","doi-asserted-by":"publisher","first-page":"3749","DOI":"10.1128\/IAI.00454-09","article-title":"Role of dendritic cells and alveolar macrophages in regulating early host defense against pulmonary infection with Cryptococcus neoformans","volume":"77","author":"Osterholzer","year":"2009","journal-title":"Infect Immun"},{"key":"B64","doi-asserted-by":"publisher","first-page":"e42","DOI":"10.1371\/journal.ppat.0010042","article-title":"The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus","volume":"1","author":"Steele","year":"2005","journal-title":"PLoS Pathog"},{"key":"B65","doi-asserted-by":"crossref","first-page":"22","DOI":"10.4049\/jimmunol.147.1.22","article-title":"Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells","volume":"147","author":"Hestdal","year":"1991","journal-title":"J Immunol"},{"key":"B66","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1128\/IAI.73.1.114-125.2005","article-title":"The pathogenesis of fatal outcome in murine pulmonary aspergillosis depends on the neutrophil depletion strategy","volume":"73","author":"Stephens-Romero","year":"2005","journal-title":"Infect Immun"},{"key":"B67","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/ni.2797","article-title":"Activation of neutrophils by autocrine IL-17A-IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORgammat and dectin-2","volume":"15","author":"Taylor","year":"2014","journal-title":"Nat Immunol"},{"key":"B68","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.4049\/jimmunol.1501811","article-title":"Human neutrophils use different mechanisms to kill Aspergillus fumigatus conidia and hyphae: evidence from phagocyte defects","volume":"196","author":"Gazendam","year":"2016","journal-title":"J Immunol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1038\/32588","article-title":"Dendritic cells and the control of immunity","volume":"392","author":"Banchereau","year":"1998","journal-title":"Nature"},{"key":"B70","doi-asserted-by":"publisher","first-page":"F9","DOI":"10.1084\/jem.20012040","article-title":"Dendritic and natural killer cells cooperate in the control\/switch of innate immunity","volume":"195","author":"Zitvogel","year":"2002","journal-title":"J Exp Med"},{"key":"B71","first-page":"47","article-title":"The proliferative response of T cells to Aspergillus antigen requires prior presentation on dendritic cells","volume":"11","author":"Ramadan","year":"2004","journal-title":"Egypt J Immunol"},{"key":"B72","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1111\/j.1365-2567.2010.03302.x","article-title":"Enhancement of anti-Aspergillus T helper type 1 response by interferon-beta-conditioned dendritic cells","volume":"131","author":"Gafa","year":"2010","journal-title":"Immunology"},{"key":"B73","doi-asserted-by":"publisher","first-page":"3807","DOI":"10.1182\/blood-2003-03-0748","article-title":"A dendritic cell vaccine against invasive aspergillosis in allogeneic hematopoietic transplantation","volume":"102","author":"Bozza","year":"2003","journal-title":"Blood"},{"key":"B74","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1086\/528694","article-title":"Proinflammatory response of immature human dendritic cells is mediated by dectin-1 after exposure to Aspergillus fumigatus germ tubes","volume":"197","author":"Mezger","year":"2008","journal-title":"J Infect Dis"},{"key":"B75","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1128\/IAI.00097-12","article-title":"Neutrophils mediate maturation and efflux of lung dendritic cells in response to Aspergillus fumigatus germ tubes","volume":"80","author":"Park","year":"2012","journal-title":"Infect Immun"},{"key":"B76","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1016\/j.micinf.2007.03.015","article-title":"In vitro infection of human dendritic cells by Aspergillus fumigatus conidia triggers the secretion of chemokines for neutrophil and Th1 lymphocyte recruitment","volume":"9","author":"Gafa","year":"2007","journal-title":"Microbes Infect"},{"key":"B77","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1038\/ni1582","article-title":"Functions of natural killer cells","volume":"9","author":"Vivier","year":"2008","journal-title":"Nat Immunol"},{"key":"B78","doi-asserted-by":"publisher","first-page":"3541","DOI":"10.1007\/s00018-011-0803-6","article-title":"Natural killer cell receptor-expressing innate lymphocytes: more than just NK cells","volume":"68","author":"Mortha","year":"2011","journal-title":"Cell Mol Life Sci"},{"key":"B79","doi-asserted-by":"publisher","first-page":"285","DOI":"10.4049\/jimmunol.1200861","article-title":"Memory CD4+ T cells are required for optimal NK cell effector functions against the opportunistic fungal pathogen Pneumocystis murina","volume":"190","author":"Kelly","year":"2013","journal-title":"J Immunol"},{"key":"B80","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1093\/infdis\/jiq062","article-title":"Human natural killer cells exhibit direct activity against Aspergillus fumigatus hyphae, but not against resting conidia","volume":"203","author":"Schmidt","year":"2011","journal-title":"J Infect Dis"},{"key":"B81","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3389\/fmicb.2012.00413","article-title":"Direct interaction studies between Aspergillus fumigatus and human immune cells; what have we learned about pathogenicity and host immunity?","volume":"3","author":"Morton","year":"2012","journal-title":"Front Microbiol"},{"key":"B82","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1128\/IAI.59.5.1747-1754.1991","article-title":"Murine natural killer cells are fungicidal to Cryptococcus neoformans","volume":"59","author":"Hidore","year":"1991","journal-title":"Infect Immun"},{"key":"B83","doi-asserted-by":"publisher","first-page":"e6854","DOI":"10.1371\/journal.pone.0006854","article-title":"Insights into the mechanisms of protective immunity against Cryptococcus neoformans infection using a mouse model of pulmonary cryptococcosis","volume":"4","author":"Wozniak","year":"2009","journal-title":"PLoS ONE"},{"key":"B84","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1080\/08830180213274","article-title":"Cryptococcal infection and Th1-Th2 cytokine balance","volume":"21","author":"Koguchi","year":"2002","journal-title":"Int Rev Immunol"},{"key":"B85","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1038\/nature06471","article-title":"Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease","volume":"451","author":"Romani","year":"2008","journal-title":"Nature"},{"key":"B86","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1182\/blood-2011-06-362582","article-title":"TLR3 essentially promotes protective class I-restricted memory CD8(+) T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients","volume":"119","author":"Carvalho","year":"2012","journal-title":"Blood"},{"key":"B87","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1186\/rr25","article-title":"Epithelial antimicrobial peptides in host defense against infection","volume":"1","author":"Bals","year":"2000","journal-title":"Respir Res"},{"key":"B88","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1128\/IAI.65.4.1510-1514.1997","article-title":"Internalization of Aspergillus fumigatus conidia by epithelial and endothelial cells","volume":"65","author":"Paris","year":"1997","journal-title":"Infect Immun"},{"key":"B89","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1038\/cmi.2010.43","article-title":"Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO. Cell Mol Immunol","volume":"7","author":"de Luca","year":"2010"},{"key":"B90","doi-asserted-by":"publisher","first-page":"286","DOI":"10.3389\/fimmu.2012.00286","article-title":"DAMP signaling in fungal infections and diseases","volume":"3","author":"Cunha","year":"2012","journal-title":"Front Immunol"},{"key":"B91","doi-asserted-by":"publisher","first-page":"145","DOI":"10.3389\/fcimb.2014.00145","article-title":"Fungal glycans and the innate immune recognition","volume":"4","author":"Barreto-Bergter","year":"2014","journal-title":"Front Cell Infect Microbiol"},{"key":"B92","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1038\/ni1408","article-title":"Dectin-1 is required for beta-glucan recognition and control of fungal infection","volume":"8","author":"Taylor","year":"2007","journal-title":"Nat Immunol"},{"key":"B93","doi-asserted-by":"publisher","first-page":"38854","DOI":"10.1074\/jbc.M606542200","article-title":"Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses","volume":"281","author":"Sato","year":"2006","journal-title":"J Biol Chem"},{"key":"B94","doi-asserted-by":"publisher","first-page":"288","DOI":"10.3389\/fimmu.2014.00288","article-title":"MCL and Mincle: C-Type lectin receptors that sense damaged self and pathogen-associated molecular patterns","volume":"5","author":"Richardson","year":"2014","journal-title":"Front Immunol"},{"key":"B95","doi-asserted-by":"publisher","first-page":"254","DOI":"10.2174\/157339512800671985","article-title":"Innate immunity and the role of epithelial barrier during Aspergillus fumigatus infection","volume":"8","author":"Svirshchevskaya","year":"2012","journal-title":"Curr Immunol Rev"},{"key":"B96","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1038\/nature25974","article-title":"Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus","volume":"555","author":"Stappers","year":"2018","journal-title":"Nature"},{"key":"B97","doi-asserted-by":"publisher","first-page":"2872","DOI":"10.4049\/jimmunol.168.6.2872","article-title":"Optimal T cell responses to Cryptococcus neoformans mannoprotein are dependent on recognition of conjugated carbohydrates by mannose receptors","volume":"168","author":"Mansour","year":"2002","journal-title":"J Immunol"},{"key":"B98","doi-asserted-by":"publisher","first-page":"3053","DOI":"10.4049\/jimmunol.176.5.3053","article-title":"Cryptococcus neoformans glycoantigens are captured by multiple lectin receptors and presented by dendritic cells","volume":"176","author":"Mansour","year":"2006","journal-title":"J Immunol"},{"key":"B99","doi-asserted-by":"publisher","first-page":"5420","DOI":"10.1128\/IAI.73.9.5420-5425.2005","article-title":"Involvement of toll-like receptor 2 in experimental invasive pulmonary aspergillosis","volume":"73","author":"Balloy","year":"2005","journal-title":"Infect Immun"},{"key":"B100","doi-asserted-by":"publisher","first-page":"3059","DOI":"10.4049\/jimmunol.172.5.3059","article-title":"The contribution of the Toll-like\/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo","volume":"172","author":"Bellocchio","year":"2004","journal-title":"J Immunol"},{"key":"B101","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/j.clim.2007.05.004","article-title":"Role of toll-like receptors in lung innate defense against invasive aspergillosis","volume":"124","author":"Chignard","year":"2007","journal-title":"Clin Immunol"},{"key":"B102","doi-asserted-by":"publisher","first-page":"4195","DOI":"10.2174\/138161206778743538","article-title":"Recognition of fungal pathogens by toll-like receptors","volume":"12","author":"Netea","year":"2006","journal-title":"Curr Pharm Des"},{"key":"B103","doi-asserted-by":"publisher","first-page":"4031","DOI":"10.4049\/jimmunol.170.8.4031","article-title":"IL-1 receptor-associated kinase 4 is essential for IL-18-mediated NK and Th1 cell responses","volume":"170","author":"Suzuki","year":"2003","journal-title":"J Immunol"},{"key":"B104","doi-asserted-by":"publisher","first-page":"4022","DOI":"10.4049\/jimmunol.180.6.4022","article-title":"Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection","volume":"180","author":"Bozza","year":"2008","journal-title":"J Immunol"},{"key":"B105","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.cellimm.2009.02.001","article-title":"The GITRL-GITR system alters TLR-4 expression on DC during fungal infection","volume":"257","author":"Vecchiarelli","year":"2009","journal-title":"Cell Immunol"},{"key":"B106","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1002\/eji.200425818","article-title":"GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily","volume":"35","author":"Nocentini","year":"2005","journal-title":"Eur J Immunol"},{"key":"B107","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/S1097-2765(00)80136-7","article-title":"MyD88 is an adaptor protein in the hToll\/IL-1 receptor family signaling pathways","volume":"2","author":"Medzhitov","year":"1998","journal-title":"Mol Cell"},{"key":"B108","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1128\/IAI.00927-07","article-title":"MyD88 signaling contributes to early pulmonary responses to Aspergillus fumigatus","volume":"76","author":"Bretz","year":"2008","journal-title":"Infect Immun"},{"key":"B109","doi-asserted-by":"publisher","first-page":"2913","DOI":"10.4049\/jimmunol.173.5.2913","article-title":"Cutting edge: TNFR-associated factor (TRAF) 6 is essential for MyD88-dependent pathway but not toll\/IL-1 receptor domain-containing adaptor-inducing IFN-beta (TRIF)-dependent pathway in TLR signaling","volume":"173","author":"Gohda","year":"2004","journal-title":"J Immunol"},{"key":"B110","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1189\/jlb.0907629","article-title":"TRAF6 distinctively mediates MyD88- and IRAK-1-induced activation of NF-kappaB. J Leukoc Biol","volume":"83","author":"Muroi","year":"2008"},{"key":"B111","doi-asserted-by":"publisher","first-page":"44143","DOI":"10.1074\/jbc.M112.414276","article-title":"Tumor necrosis factor receptor-associated factor 6 (TRAF6) and TGFbeta-activated kinase 1 (TAK1) play essential roles in the C-type lectin receptor signaling in response to Candida albicans infection","volume":"287","author":"Gorjestani","year":"2012","journal-title":"J Biol Chem"},{"key":"B112","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.it.2009.03.002","article-title":"CARD9 versus CARMA1 in innate and adaptive immunity","volume":"30","author":"Hara","year":"2009","journal-title":"Trends Immunol"},{"key":"B113","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.4049\/jimmunol.1300132","article-title":"Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1\/Syk kinase signaling","volume":"191","author":"Kyrmizi","year":"2013","journal-title":"J Immunol"},{"key":"B114","doi-asserted-by":"publisher","first-page":"4890","DOI":"10.4049\/jimmunol.1100381","article-title":"Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection","volume":"187","author":"Fang","year":"2011","journal-title":"J Immunol"},{"key":"B115","doi-asserted-by":"publisher","first-page":"15","DOI":"10.3389\/fmicb.2011.00015","article-title":"The inflammasomes: molecular effectors of host resistance against bacterial, viral, parasitic, and fungal infections","volume":"2","author":"Skeldon","year":"2011","journal-title":"Front Microbiol"},{"key":"B116","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1016\/j.immuni.2013.05.016","article-title":"K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter","volume":"38","author":"Munoz-Planillo","year":"2013","journal-title":"Immunity"},{"key":"B117","doi-asserted-by":"publisher","first-page":"3937","DOI":"10.4049\/jimmunol.1402658","article-title":"K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling","volume":"194","author":"Katsnelson","year":"2015","journal-title":"J Immunol"},{"key":"B118","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1016\/j.immuni.2016.08.010","article-title":"K(+) Efflux-independent NLRP3 inflammasome activation by small molecules targeting mitochondria","volume":"45","author":"Gross","year":"2016","journal-title":"Immunity"},{"key":"B119","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1007\/s10753-017-0674-6","article-title":"Fungal beta-Glucan Activates the NLRP3 inflammasome in human bronchial epithelial cells through ROS production","volume":"41","author":"Huang","year":"2018","journal-title":"Inflammation"},{"key":"B120","doi-asserted-by":"publisher","first-page":"8061","DOI":"10.4049\/jimmunol.0902477","article-title":"Involvement of the NLRP3 inflammasome in innate and humoral adaptive immune responses to fungal beta-glucan","volume":"183","author":"Kumar","year":"2009","journal-title":"J Immunol"},{"key":"B121","doi-asserted-by":"publisher","first-page":"e10008","DOI":"10.1371\/journal.pone.0010008","article-title":"Aspergillus fumigatus stimulates the NLRP3 inflammasome through a pathway requiring ROS production and the Syk tyrosine kinase","volume":"5","author":"Said-Sadier","year":"2010","journal-title":"PLoS ONE"},{"key":"B122","doi-asserted-by":"publisher","first-page":"20574","DOI":"10.1074\/jbc.M109.023689","article-title":"Fungal zymosan and mannan activate the cryopyrin inflammasome","volume":"284","author":"Lamkanfi","year":"2009","journal-title":"J Biol Chem"},{"key":"B123","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1016\/j.micinf.2014.08.013","article-title":"Acapsular Cryptococcus neoformans activates the NLRP3 inflammasome","volume":"16","author":"Guo","year":"2014","journal-title":"Microbes Infect"},{"key":"B124","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1038\/cr.2013.49","article-title":"Biofilm from a clinical strain of Cryptococcus neoformans activates the NLRP3 inflammasome","volume":"23","author":"Lei","year":"2013","journal-title":"Cell Res"},{"key":"B125","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.chom.2015.01.006","article-title":"Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection","volume":"17","author":"Karki","year":"2015","journal-title":"Cell Host Microbe"},{"key":"B126","doi-asserted-by":"publisher","first-page":"3717","DOI":"10.4049\/jimmunol.176.6.3717","article-title":"Dectin-1 and TLRs permit macrophages to distinguish between different Aspergillus fumigatus cellular states","volume":"176","author":"Gersuk","year":"2006","journal-title":"J Immunol"},{"key":"B127","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.imbio.2013.06.013","article-title":"Activation of NF-\u03baB and respiratory burst following Aspergillus fumigatus stimulation of macrophages","volume":"219","author":"Sun","year":"2014","journal-title":"Immunobiology"},{"key":"B128","doi-asserted-by":"publisher","first-page":"1829","DOI":"10.1084\/jem.183.4.1829","article-title":"The immunosuppressive fungal metabolite gliotoxin specifically inhibits transcription factor NF-kappaB. J Exp Med","volume":"183","author":"Pahl","year":"1996"},{"key":"B129","doi-asserted-by":"publisher","first-page":"3994","DOI":"10.4049\/jimmunol.177.6.3994","article-title":"Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4","volume":"177","author":"Dubourdeau","year":"2006","journal-title":"J Immunol"},{"key":"B130","doi-asserted-by":"publisher","first-page":"30513","DOI":"10.1074\/jbc.M803149200","article-title":"Aspergillus fumigatus-induced IL-8 synthesis by respiratory epithelial cells is controlled by the PI3 kinase, p38 MAPK and ERK1\/2 pathways and not by the TLR-MYD88 pathway","volume":"283","author":"Balloy","year":"2008","journal-title":"J Biol Chem"},{"key":"B131","doi-asserted-by":"publisher","first-page":"4620","DOI":"10.4049\/jimmunol.166.7.4620","article-title":"Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule","volume":"166","author":"Shoham","year":"2001","journal-title":"J Immunol"},{"key":"B132","doi-asserted-by":"publisher","first-page":"2140","DOI":"10.4049\/jimmunol.1602186","article-title":"IL-33 signaling regulates innate IL-17A and IL-22 production via suppression of prostaglandin E2 during lung fungal infection","volume":"199","author":"Garth","year":"2017","journal-title":"J Immunol"},{"key":"B133","doi-asserted-by":"publisher","first-page":"3526","DOI":"10.1073\/pnas.1322831111","article-title":"IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans","volume":"111","author":"de Luca","year":"2014","journal-title":"Proc Natl Acad Sci USA"},{"key":"B134","doi-asserted-by":"publisher","first-page":"4938","DOI":"10.4049\/jimmunol.0804250","article-title":"Requisite role for the dectin-1 beta-glucan receptor in pulmonary defense against Aspergillus fumigatus","volume":"182","author":"Werner","year":"2009","journal-title":"J Immunol"},{"key":"B135","doi-asserted-by":"publisher","first-page":"e1004625","DOI":"10.1371\/journal.ppat.1004625","article-title":"IL-1alpha signaling is critical for leukocyte recruitment after pulmonary Aspergillus fumigatus challenge","volume":"11","author":"Caffrey","year":"2015","journal-title":"PLoS Pathog"},{"key":"B136","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1002\/eji.201242711","article-title":"The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses","volume":"43","author":"Gresnigt","year":"2013","journal-title":"Eur J Immunol"},{"key":"B137","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.coi.2007.04.005","article-title":"Differentiation and function of Th17 T cells","volume":"19","author":"Stockinger","year":"2007","journal-title":"Curr Opin Immunol"},{"key":"B138","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/nri2800","article-title":"Innate IL-17-producing cells: the sentinels of the immune system","volume":"10","author":"Cua","year":"2010","journal-title":"Nat Rev Immunol"},{"key":"B139","doi-asserted-by":"publisher","first-page":"4665","DOI":"10.4049\/jimmunol.170.9.4665","article-title":"Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways","volume":"170","author":"Miyamoto","year":"2003","journal-title":"J Immunol"},{"key":"B140","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.immuni.2005.01.011","article-title":"Phagocytosis of apoptotic neutrophils regulates granulopoiesis via IL-23 and IL-17","volume":"22","author":"Stark","year":"2005","journal-title":"Immunity"},{"key":"B141","doi-asserted-by":"publisher","first-page":"2695","DOI":"10.1002\/eji.200737409","article-title":"IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance","volume":"37","author":"Zelante","year":"2007","journal-title":"Eur J Immunol"},{"key":"B142","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1038\/nri3581","article-title":"Regulation of type I interferon responses","volume":"14","author":"Ivashkiv","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"B143","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1111\/j.0105-2896.2004.00207.x","article-title":"The role of type I interferons in non-viral infections","volume":"202","author":"Bogdan","year":"2004","journal-title":"Immunol Rev"},{"key":"B144","doi-asserted-by":"publisher","first-page":"e0138291","DOI":"10.1371\/journal.pone.0138291","article-title":"Cryptococcus neoformans infection in mice lacking type I interferon signaling leads to increased fungal clearance and IL-4-dependent mucin production in the lungs","volume":"10","author":"Sato","year":"2015","journal-title":"PLoS ONE"},{"key":"B145","doi-asserted-by":"publisher","first-page":"566","DOI":"10.4049\/jimmunol.181.1.566","article-title":"IFN-alpha\/beta signaling is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis","volume":"181","author":"Biondo","year":"2008","journal-title":"J Immunol"},{"key":"B146","doi-asserted-by":"publisher","first-page":"3195","DOI":"10.4049\/jimmunol.168.7.3195","article-title":"IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking","volume":"168","author":"Dufour","year":"2002","journal-title":"J Immunol"},{"key":"B147","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1183\/09031936.00096110","article-title":"Aspergillus fumigatus conidia induce interferon-beta signalling in respiratory epithelial cells","volume":"39","author":"Beisswenger","year":"2012","journal-title":"Eur Respir J"},{"key":"B148","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1093\/infdis\/170.5.1331","article-title":"In vivo activity of interferon-gamma in combination with amphotericin B in the treatment of experimental cryptococcosis","volume":"170","author":"Joly","year":"1994","journal-title":"J Infect Dis"},{"key":"B149","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1093\/jac\/46.3.437","article-title":"Enhancement of antifungal chemotherapy by interferon-gamma in experimental systemic cryptococcosis","volume":"46","author":"Lutz","year":"2000","journal-title":"J Antimicrob Chemother"},{"key":"B150","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1128\/IAI.00274-06","article-title":"Protection against cryptococcosis by using a murine gamma interferon-producing Cryptococcus neoformans strain","volume":"75","author":"Wormley","year":"2007","journal-title":"Infect Immun"},{"key":"B151","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1111\/myc.12679","article-title":"Levels of interleukin (IL)-6 and IL-8 are elevated in serum and bronchoalveolar lavage fluid of haematological patients with invasive pulmonary aspergillosis","volume":"60","author":"Heldt","year":"2017","journal-title":"Mycoses"},{"key":"B152","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1172\/JCI1368","article-title":"IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses","volume":"101","author":"Xing","year":"1998","journal-title":"J Clin Invest"},{"key":"B153","doi-asserted-by":"publisher","first-page":"e0123171","DOI":"10.1371\/journal.pone.0123171","article-title":"Impaired T cell responsiveness to interleukin-6 in hematological patients with invasive aspergillosis","volume":"10","author":"Camargo","year":"2015","journal-title":"PLoS ONE"},{"key":"B154","doi-asserted-by":"crossref","first-page":"6086","DOI":"10.4049\/jimmunol.163.11.6086","article-title":"CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis","volume":"163","author":"Mehrad","year":"1999","journal-title":"J Immunol"},{"key":"B155","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1164\/rccm.200204-367OC","article-title":"Transient lung-specific expression of the chemokine KC improves outcome in invasive aspergillosis","volume":"166","author":"Mehrad","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"B156","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1086\/315027","article-title":"Proteases from Aspergillus fumigatus induce interleukin (IL)-6 and IL-8 production in airway epithelial cell lines by transcriptional mechanisms","volume":"180","author":"Borger","year":"1999","journal-title":"J Infect Dis"},{"key":"B157","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.jinf.2004.12.012","article-title":"Interaction of airway epithelial cells (A549) with spores and mycelium of Aspergillus fumigatus","volume":"51","author":"Zhang","year":"2005","journal-title":"J Infect"},{"key":"B158","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1046\/j.1365-280X.1999.00219.x","article-title":"Cytokine and chemokine responses following pulmonary challenge with Aspergillus fumigatus: obligatory role of TNF-alpha and GM-CSF in neutrophil recruitment","volume":"37","author":"Schelenz","year":"1999","journal-title":"Med Mycol"},{"key":"B159","doi-asserted-by":"crossref","first-page":"5999","DOI":"10.1128\/IAI.66.12.5999-6003.1998","article-title":"Tumor necrosis factor alpha enhances antifungal activities of polymorphonuclear and mononuclear phagocytes against Aspergillus fumigatus","volume":"66","author":"Roilides","year":"1998","journal-title":"Infect Immun"},{"key":"B160","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1128\/IAI.69.3.1554-1560.2001","article-title":"Cytokine networking in lungs of immunocompetent mice in response to inhaled Aspergillus fumigatus","volume":"69","author":"Brieland","year":"2001","journal-title":"Infect Immun"},{"key":"B161","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1615\/CritRevImmunol.v25.i5.50","article-title":"Functions of granulocyte-macrophage colony-stimulating factor","volume":"25","author":"Fleetwood","year":"2005","journal-title":"Crit Rev Immunol"},{"key":"B162","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1093\/infdis\/jiw054","article-title":"Role of granulocyte-macrophage colony-stimulating factor signaling in regulating neutrophil antifungal activity and the oxidative burst during respiratory fungal challenge","volume":"213","author":"Kasahara","year":"2016","journal-title":"J Infect Dis"},{"key":"B163","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1128\/IAI.64.8.2897-2903.1996","article-title":"Capsular polysaccharide of Cryptococcus neoformans induces proinflammatory cytokine release by human neutrophils","volume":"64","author":"Retini","year":"1996","journal-title":"Infect Immun"},{"key":"B164","doi-asserted-by":"publisher","first-page":"e00264","DOI":"10.1128\/mBio.00264-13","article-title":"Macrophage M1\/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection","volume":"4","author":"Davis","year":"2013","journal-title":"MBio"},{"key":"B165","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1093\/jac\/dki441","article-title":"Anti-inflammatory effects of moxifloxacin on IL-8, IL-1beta and TNF-alpha secretion and NFkappaB and MAP-kinase activation in human monocytes stimulated with Aspergillus fumigatus","volume":"57","author":"Shalit","year":"2006","journal-title":"J Antimicrob Chemother"},{"key":"B166","doi-asserted-by":"publisher","first-page":"3068","DOI":"10.1128\/IAI.70.6.3068-3072.2002","article-title":"beta-Defensin 1 contributes to pulmonary innate immunity in mice","volume":"70","author":"Moser","year":"2002","journal-title":"Infect Immun"},{"key":"B167","doi-asserted-by":"publisher","first-page":"2098","DOI":"10.3389\/fmicb.2017.02098","article-title":"Role of soluble innate effector molecules in pulmonary defense against fungal pathogens","volume":"8","author":"Ordonez","year":"2017","journal-title":"Front Microbiol"},{"key":"B168","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1042\/bj2560061","article-title":"Purification and characterization of the core-specific lectin from human serum and liver","volume":"256","author":"Colley","year":"1988","journal-title":"Biochem J"},{"key":"B169","doi-asserted-by":"publisher","first-page":"4769","DOI":"10.1128\/IAI.00536-07","article-title":"Binding of serum mannan binding lectin to a cell integrity-defective Cryptococcus neoformans ccr4Delta mutant","volume":"75","author":"Panepinto","year":"2007","journal-title":"Infect Immun"},{"key":"B170","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1111\/j.1365-2249.2007.03351.x","article-title":"Protective role of mannan-binding lectin in a murine model of invasive pulmonary aspergillosis","volume":"148","author":"Kaur","year":"2007","journal-title":"Clin Exp Immunol"},{"key":"B171","doi-asserted-by":"publisher","first-page":"2783","DOI":"10.1128\/IAI.00088-09","article-title":"Surfactant protein D increases phagocytosis of hypocapsular Cryptococcus neoformans by murine macrophages and enhances fungal survival","volume":"77","author":"Geunes-Boyer","year":"2009","journal-title":"Infect Immun"},{"key":"B172","doi-asserted-by":"publisher","first-page":"2444","DOI":"10.1128\/IAI.05613-11","article-title":"Surfactant protein D facilitates Cryptococcus neoformans infection","volume":"80","author":"Geunes-Boyer","year":"2012","journal-title":"Infect Immun"},{"key":"B173","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1177\/1753425910369271","article-title":"Review: soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation","volume":"16","author":"Litvack","year":"2010","journal-title":"Innate Immun"},{"key":"B174","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1111\/imm.12501","article-title":"H-ficolin binds Aspergillus fumigatus leading to activation of the lectin complement pathway and modulation of lung epithelial immune responses","volume":"146","author":"Bidula","year":"2015","journal-title":"Immunology"},{"key":"B175","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1093\/infdis\/jiv027","article-title":"The serum opsonin L-ficolin is detected in lungs of human transplant recipients following fungal infections and modulates inflammation and killing of Aspergillus fumigatus","volume":"212","author":"Bidula","year":"2015","journal-title":"J Infect Dis"},{"key":"B176","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1471-2180-9-33","article-title":"Inducible expression of beta defensins by human respiratory epithelial cells exposed to Aspergillus fumigatus organisms","volume":"9","author":"Alekseeva","year":"2009","journal-title":"BMC Microbiol"},{"key":"B177","doi-asserted-by":"publisher","first-page":"L750","DOI":"10.1152\/ajplung.00326.2003","article-title":"Secretion of lactoferrin and lysozyme by cultures of human airway epithelium","volume":"286","author":"Dubin","year":"2004","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"B178","first-page":"313","article-title":"Damage to hyphal forms of fungi by human leukocytes in vitro","volume":"91","author":"Diamond","year":"1978","journal-title":"Am J Pathol"},{"key":"B179","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.1093\/nar\/18.7.1911","article-title":"Recent origin of the P lysozyme gene in mice","volume":"18","author":"Cortopassi","year":"1990","journal-title":"Nucleic Acids Res"},{"key":"B180","doi-asserted-by":"publisher","first-page":"6232","DOI":"10.1073\/pnas.85.17.6232","article-title":"Mouse lysozyme M gene: isolation, characterization, and expression studies","volume":"85","author":"Cross","year":"1988","journal-title":"Proc Natl Acad Sci USA"},{"key":"B181","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1128\/EC.00139-06","article-title":"Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus","volume":"5","author":"Steinbach","year":"2006","journal-title":"Eukaryot Cell"},{"key":"B182","doi-asserted-by":"publisher","first-page":"1085","DOI":"10.1128\/EC.00086-08","article-title":"Calcineurin target CrzA regulates conidial germination, hyphal growth, and pathogenesis of Aspergillus fumigatus","volume":"7","author":"Cramer","year":"2008","journal-title":"Eukaryot Cell"},{"key":"B183","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.fgb.2006.08.004","article-title":"Functional characterization of the Aspergillus fumigatus calcineurin","volume":"44","author":"da Silva Ferreira","year":"2007","journal-title":"Fungal Genet Biol"},{"key":"B184","doi-asserted-by":"publisher","first-page":"2979","DOI":"10.1128\/AAC.01394-06","article-title":"Calcineurin inhibition or mutation enhances cell wall inhibitors against Aspergillus fumigatus","volume":"51","author":"Steinbach","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"B185","doi-asserted-by":"publisher","first-page":"2576","DOI":"10.1093\/emboj\/16.10.2576","article-title":"Calcineurin is required for virulence of Cryptococcus neoformans","volume":"16","author":"Odom","year":"1997","journal-title":"EMBO J"},{"key":"B186","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1016\/j.jaci.2016.02.026","article-title":"Calcineurin inhibitors impair neutrophil activity against Aspergillus fumigatus in allogeneic hematopoietic stem cell transplant recipients","volume":"138","author":"Imbert","year":"2016","journal-title":"J Allergy Clin Immunol"},{"key":"B187","doi-asserted-by":"publisher","first-page":"240","DOI":"10.15252\/emmm.201404556","article-title":"Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus","volume":"7","author":"Herbst","year":"2015","journal-title":"EMBO Mol Med"},{"key":"B188","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1086\/511438","article-title":"Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality","volume":"195","author":"Singh","year":"2007","journal-title":"J Infect Dis"},{"key":"B189","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.cell.2007.12.018","article-title":"Autophagy in the pathogenesis of disease","volume":"132","author":"Levine","year":"2008","journal-title":"Cell"},{"key":"B190","doi-asserted-by":"publisher","first-page":"2295","DOI":"10.2169\/internalmedicine.52.1118","article-title":"Autophagy in the pathogenesis of pulmonary disease","volume":"52","author":"Araya","year":"2013","journal-title":"Intern Med"},{"key":"B191","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/978-3-319-07320-0_6","article-title":"Autophagy is an inflammation-related defensive mechanism against disease","volume":"824","author":"Joven","year":"2014","journal-title":"Adv Exp Med Biol"},{"key":"B192","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1080\/15548627.2017.1389823","article-title":"Autophagy and inflammation in chronic respiratory disease","volume":"14","author":"Racanelli","year":"2018","journal-title":"Autophagy"},{"key":"B193","doi-asserted-by":"publisher","first-page":"147","DOI":"10.3389\/fcell.2018.00147","article-title":"Selective autophagy and xenophagy in infection and disease","volume":"6","author":"Sharma","year":"2018","journal-title":"Front Cell Dev Biol"},{"key":"B194","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1080\/15548627.2016.1267075","article-title":"Xenophagy: a battlefield between host and microbe, and a possible avenue for cancer treatment","volume":"13","author":"Mao","year":"2017","journal-title":"Autophagy"},{"key":"B195","doi-asserted-by":"publisher","first-page":"526","DOI":"10.4161\/auto.27606","article-title":"LC3-associated phagocytosis","volume":"10","author":"Romao","year":"2014","journal-title":"Autophagy"},{"key":"B196","doi-asserted-by":"publisher","first-page":"396","DOI":"10.3390\/cells1030396","article-title":"LC3-Associated Phagocytosis (LAP): connections with host autophagy","volume":"1","author":"Lai","year":"2012","journal-title":"Cells"},{"key":"B197","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.cell.2018.08.061","article-title":"LC3-Associated phagocytosis in myeloid cells promotes tumor immune tolerance","volume":"175","author":"Cunha","year":"2018","journal-title":"Cell"},{"key":"B198","doi-asserted-by":"publisher","first-page":"3065","DOI":"10.1128\/IAI.00358-12","article-title":"Macrophage autophagy in immunity to Cryptococcus neoformans and Candida albicans","volume":"80","author":"Nicola","year":"2012","journal-title":"Infect Immun"},{"key":"B199","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1080\/15548627.2016.1157242","article-title":"Melanin targets LC3-associated phagocytosis (LAP): a novel pathogenetic mechanism in fungal disease","volume":"12","author":"Chamilos","year":"2016","journal-title":"Autophagy"},{"key":"B200","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.chom.2015.12.002","article-title":"Aspergillus cell wall melanin blocks LC3-associated phagocytosis to promote pathogenicity","volume":"19","author":"Akoumianaki","year":"2016","journal-title":"Cell Host Microbe"},{"key":"B201","doi-asserted-by":"publisher","first-page":"1253","DOI":"10.1038\/nature06421","article-title":"Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis","volume":"450","author":"Sanjuan","year":"2007","journal-title":"Nature"},{"key":"B202","doi-asserted-by":"publisher","first-page":"17396","DOI":"10.1073\/pnas.1113421108","article-title":"Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells","volume":"108","author":"Martinez","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"B203","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1038\/ncb3192","article-title":"Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins","volume":"17","author":"Martinez","year":"2015","journal-title":"Nat Cell Biol"},{"key":"B204","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.2217\/fmb-2016-0090","article-title":"The putative autophagy regulator Atg7 affects the physiology and pathogenic mechanisms of Cryptococcus neoformans","volume":"11","author":"Oliveira","year":"2016","journal-title":"Fut Microbiol"},{"key":"B205","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1172\/JCI32053","article-title":"PI3K signaling of autophagy is required for starvation tolerance and virulence of Cryptococcus neoformans","volume":"118","author":"Hu","year":"2008","journal-title":"J Clin Invest"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01524\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T23:44:09Z","timestamp":1694994249000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01524\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,3]]},"references-count":205,"alternative-id":["10.3389\/fimmu.2019.01524"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2019.01524","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,3]]},"article-number":"1524"}}