{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:56:30Z","timestamp":1790787390884,"version":"4.1.0"},"reference-count":86,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T00:00:00Z","timestamp":1565654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003323","name":"Agence Nationale de Recherches sur le Sida et les H\u00e9patites Virales","doi-asserted-by":"publisher","award":["ANRS-12274"],"award-info":[{"award-number":["ANRS-12274"]}],"id":[{"id":"10.13039\/501100003323","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["Project DECIT\/CNPq 404573\/2012-6"],"award-info":[{"award-number":["Project DECIT\/CNPq 404573\/2012-6"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006507","name":"Funda\u00e7\u00e3o Oswaldo Cruz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006507","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2019.01800","type":"journal-article","created":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T04:18:00Z","timestamp":1565669880000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Changes in the NK Cell Repertoire Related to Initiation of TB Treatment and Onset of Immune Reconstitution Inflammatory Syndrome in TB\/HIV Co-infected Patients in Rio de Janeiro, Brazil\u2014ANRS 12274"],"prefix":"10.3389","volume":"10","author":[{"given":"Carmem Beatriz Wagner","family":"Giacoia-Gripp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andressa da Silva","family":"Cazote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana Pereira","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1via Marinho","family":"Sant'Anna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Arana Stanis","family":"Schmaltz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania de Souza","family":"Brum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Arruda","family":"de Matos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00falio","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aline","family":"Benjamin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Henrique","family":"Pilotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria Cavalcanti","family":"Rolla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariza Gon\u00e7alves","family":"Morgado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Scott-Algara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,8,13]]},"reference":[{"key":"B1","unstructured":"Global Tuberculosis Report.2018"},{"key":"B2","unstructured":"WHO Fact Sheets on TB.2018"},{"key":"B3","unstructured":"Boletim Epidemiol\u00f3gico 2008-2016.2016"},{"key":"B4","unstructured":"Coinfec\u00e7\u00e3o TB-HIV No Brasil: Panorama Epidemiol\u00f3gico E Atividades Colaborativas.2017"},{"key":"B5","unstructured":"Secretaria de Vigil\u00e2ncia Em Sa\u00fade, Minist\u00e9rio Da Sa\u00fade. v. 49.2018"},{"key":"B6","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1097\/COH.0b013e3283339309","article-title":"Management of individuals requiring antiretroviral therapy and TB treatment","volume":"5","author":"Cohen","year":"2010","journal-title":"Curr Opin HIV AIDS."},{"key":"B7","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/S1473-3099(15)70008-3","article-title":"Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective obse","volume":"15","author":"Ravimohan","year":"2015","journal-title":"Lancet Infect Dis."},{"key":"B8","doi-asserted-by":"publisher","first-page":"841","DOI":"10.3851\/IMP2108","article-title":"TB-IRIS Study Group. Clinical spectrum, risk factors and outcome of immune reconstitution inflammatory syndrome in patients with tuberculosis-HIV coinfection","volume":"17","author":"Worodria","year":"2012","journal-title":"Antivir Ther."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1995","DOI":"10.1002\/eji.201343632","article-title":"The Immunopathogenesis of the HIV tuberculosis immune reconstitution inflammatory syndrome","volume":"43","author":"Lai","year":"2013","journal-title":"Eur J Immunol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1097\/QAI.0000000000000030","article-title":"Tuberculosis immune reconstitution inflammatory syndrome in A5221 STRIDE: timing, severity, and implications for HIV-TB programs","volume":"65","author":"Luetkemeyer","year":"2014","journal-title":"J Acquir Immune Defic Syndr."},{"key":"B11","doi-asserted-by":"publisher","first-page":"49","DOI":"10.2147\/HIV.S42328","article-title":"Immune reconstitution inflammatory syndrome in HIV-infected patients","volume":"7","author":"Walker","year":"2015","journal-title":"HIV\/AIDS."},{"key":"B12","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1097\/COH.0000000000000502","article-title":"The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research","volume":"13","author":"Walker","year":"2018","journal-title":"Curr Opin HIV AIDS."},{"key":"B13","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1097\/QAD.0b013e3280b079c8","article-title":"Immune reconstitution syndrome in tuberculosis and HIV-co-infected patients: Th1 explosion or cytokine storm?","volume":"21","author":"Ruhwald","year":"2007","journal-title":"AIDS."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1093\/cid\/cis577","article-title":"Corticosteroid therapy, vitamin D status, and inflammatory cytokine profile in the HIV-tuberculosis immune reconstitution inflammatory syndrome","volume":"55","author":"Conesa-Botella","year":"2012","journal-title":"Clin Infect Dis."},{"key":"B15","doi-asserted-by":"publisher","first-page":"676","DOI":"10.4049\/jimmunol.1301004","article-title":"Role of IL-6 in Mycobacterium avium-associated immune reconstitution inflammatory syndrome","volume":"192","author":"Barber","year":"2013","journal-title":"J Immunol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"F1","DOI":"10.1097\/01.aids.0000202648.18526.bf","article-title":"Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients","volume":"20","author":"Bourgarit","year":"2006","journal-title":"AIDS."},{"key":"B17","doi-asserted-by":"publisher","first-page":"3915","DOI":"10.4049\/jimmunol.0804020","article-title":"Tuberculosis-associated immune restoration syndrome in HIV-1-infected patients involves tuberculin-specific CD4 Th1 cells and KIR-negative T cells","volume":"183","author":"Bourgarit","year":"2009","journal-title":"J Immunol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1164\/rccm.200806-858OC","article-title":"Type 1 helper T cells and FoxP3-positive T cells in HIV-tuberculosis- associated immune reconstitution inflammatory syndrome","volume":"178","author":"Meintjes","year":"2008","journal-title":"Am J Respir Crit Care Med."},{"key":"B19","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1186\/s12879-017-2700-6","article-title":"Risk factors for increased immune reconstitution in response to Mycobacterium tuberculosis antigens in tuberculosis HIV-infected, antiretroviral-na\u00efve patients","volume":"17","author":"Silva","year":"2017","journal-title":"BMC Infect Dis."},{"key":"B20","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1097\/QAI.0b013e31822e0d15","article-title":"Natural killer cell activation distinguishes Mycobacterium tuberculosis-mediated immune reconstitution syndrome from chronic HIV and HIV\/MTB coinfection","volume":"58","author":"Conradie","year":"2011","journal-title":"J Acquir Immune Defic Syndr."},{"key":"B21","doi-asserted-by":"publisher","first-page":"3315","DOI":"10.1182\/blood-2011-09-377523","article-title":"Natural killer cell degranulation capacity predicts early onset of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients with tuberculosis","volume":"119","author":"Pean","year":"2012","journal-title":"Blood."},{"key":"B22","doi-asserted-by":"publisher","first-page":"e1004433","DOI":"10.1371\/journal.ppat.1004433","article-title":"Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-associated immune reconstitution inflammatory syndrome","volume":"10","author":"Andrade","year":"2014","journal-title":"PLoS Pathog."},{"key":"B23","doi-asserted-by":"publisher","first-page":"8451","DOI":"10.1038\/ncomms9451","article-title":"HIV-Tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by toll-like receptor and inflammasome signalling","volume":"6","author":"Lai","year":"2015","journal-title":"Nat Commun."},{"key":"B24","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1097\/QAD.0000000000000557","article-title":"Plasma interleukin-18 levels are a biomarker of innate immune responses that predict and characterize tuberculosis-associated immune reconstitution inflammatory syndrome","volume":"29","author":"Tan","year":"2015","journal-title":"AIDS."},{"key":"B25","doi-asserted-by":"publisher","first-page":"4052","DOI":"10.4049\/jimmunol.1502203","article-title":"aberrant inflammasome activation characterizes tuberculosis-associated immune reconstitution inflammatory syndrome","volume":"196","author":"Tan","year":"2016","journal-title":"J Immunol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1097\/QAI.0000000000001582","article-title":"Neutrophil activation and enhanced release of granule products in HIV-TB immune reconstitution inflammatory syndrome","volume":"77","author":"Nakiwala","year":"2018","journal-title":"J Acquir Immune Defic Syndr."},{"key":"B27","first-page":"515","article-title":"HIV-associated tuberculosis in developing countries: clinical features, diagnosis, and treatment","volume":"70","author":"Raviglione","year":"1992","journal-title":"Bull World Health Organ."},{"key":"B28","doi-asserted-by":"publisher","first-page":"e0066095","DOI":"10.1371\/journal.pone.0066095","article-title":"T cell activation and cytokine profile of tuberculosis and HIV-positive individuals during antituberculous treatment and efavirenz-based regimens","volume":"8","author":"Silva","year":"2013","journal-title":"PLoS ONE."},{"key":"B29","unstructured":"Tuberculosis Fact Sheet.2015"},{"key":"B30","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.tube.2010.08.005","article-title":"The mechanisms and consequences of the extra-pulmonary dissemination of Mycobacterium tuberculosis","volume":"90","author":"Krishnan","year":"2010","journal-title":"Tuberculosis."},{"key":"B31","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1093\/cid\/cis303","article-title":"Site of extrapulmonary tuberculosis is associated with HIV infection","volume":"55","author":"Leeds","year":"2012","journal-title":"Clin Infect Dis."},{"key":"B32","doi-asserted-by":"publisher","first-page":"006","DOI":"10.23937\/ijtd-2017\/1710006","article-title":"Extrapulmonary tuberculosis: update on the epidemiology, risk factors and prevention strategies","volume":"1","author":"Ayed","year":"2018","journal-title":"Int J Trop Dis."},{"key":"B33","volume-title":"Extra Pulmonary Tuberculosis: An Overview, Role of Microbes in Human Health and Diseases (December 10th 2018), Nar Singh Chauhan.","author":"Cantres-Fonseca","year":"2018"},{"key":"B34","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1007\/s11515-015-1358-y","article-title":"The bacterial and host factors associated with extrapulmonary dissemination of Mycobacterium tuberculosis","volume":"10","author":"Yang","year":"2015","journal-title":"Front Biol."},{"key":"B35","unstructured":"Protocolo Cl\u00ednico E Diretrizes Terap\u00eauticas Para O Manejo Da Infec\u00e7\u00e3o Pelo HIV Em Adultos.2018"},{"key":"B36","unstructured":"284pManual de Recomenda\u00e7\u00f5es para o Controle da Tuberculose no Brasil. Minist\u00e9rio da Sa\u00fade, Secretaria de Vigil\u00e2ncia em Sa\u00fade, Departamento de Vigil\u00e2ncia Epidemiol\u00f3gica.2011"},{"key":"B37","doi-asserted-by":"publisher","first-page":"e0217014","DOI":"10.1371\/journal.pone.0217014","article-title":"Predictors of early mortality and effectiveness of antiretroviral therapy in TB-HIV patients from Brazil","volume":"14","author":"Demitto","year":"2019","journal-title":"PLoS ONE."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1639","DOI":"10.1086\/503903","article-title":"Immune reconstitution syndrome in HIV: validating a case definition and identifying clinical predictors in persons initiating antiretroviral therapy","volume":"42","author":"Robertson","year":"2006","journal-title":"Clin Infect Dis."},{"key":"B39","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1016\/S1473-3099(08)70184-1","article-title":"Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings","volume":"8","author":"Meintjes","year":"2008","journal-title":"Lancet Infect Dis."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1365-2567.2007.02647.x","article-title":"Characterization of human invariant natural killer t subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11","volume":"122","author":"Montoya","year":"2007","journal-title":"Immunology."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1002\/eji.200737389","article-title":"Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR alpha-chain CDR3 loop","volume":"38","author":"Exley","year":"2008","journal-title":"Eur J Immunol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jim.2017.03.016","article-title":"Comparison of 6B11 mAb and \u03b1-GalCer-loaded CD1d dextramers for detection of iNKT cells by flow cytometry","volume":"446","author":"Lenart","year":"2017","journal-title":"J Immunol Methods."},{"key":"B43","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.jim.2004.08.008","article-title":"CD107a as a functional marker for the identification of natural killer cell activity","volume":"294","author":"Alter","year":"2004","journal-title":"J Immunol Methods."},{"key":"B44","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1186\/1471-2105-9-221","article-title":"Highly accurate sigmoidal fitting of real-time PCR data by introducing a parameter for asymmetry","volume":"9","author":"Spiess","year":"2008","journal-title":"BMC Bioinformatics."},{"key":"B45","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1590\/S1413-86702007000500004","article-title":"Immune Reconstitution syndrome in patients treated for HIV and tuberculosis in Rio de Janeiro","volume":"11","author":"Serra","year":"2007","journal-title":"Braz J Infect Dis."},{"key":"B46","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1186\/1741-7015-11-253","article-title":"Management of HIV-associated tuberculosis in resource-limited settings: a state-of-the-art review","volume":"11","author":"Lawn","year":"2013","journal-title":"BMC Med."},{"key":"B47","doi-asserted-by":"publisher","first-page":"15011","DOI":"10.1073\/pnas.2336091100","article-title":"Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates","volume":"100","author":"Mavilio","year":"2003","journal-title":"Proc Natl Acad Sci USA."},{"key":"B48","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1089\/aid.2009.0176","article-title":"Alterations in natural killer cell receptor profiles during HIV type 1 disease progression among chronically infected South African adults","volume":"26","author":"Wong","year":"2010","journal-title":"AIDS Res Hum Retroviruses."},{"key":"B49","doi-asserted-by":"publisher","first-page":"4611","DOI":"10.4049\/jimmunol.175.7.4611","article-title":"Role of NK cell-activating receptors and their ligands in the lysis of mononuclear phagocytes infected with an intracellular bacterium","volume":"175","author":"Vankayalapati","year":"2005","journal-title":"J Immunol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"386389","DOI":"10.1111\/j.1399-0039.2006.00685.x","article-title":"Study of KIR genes in tuberculosis patients","volume":"68","author":"M\u00e9ndez","year":"2006","journal-title":"Tissue Antigens."},{"key":"B51","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1093\/intimm\/dxp046","article-title":"Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment","volume":"21","author":"Bozzano","year":"2009","journal-title":"Int Immunol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.humimm.2012.10.006","article-title":"Killer cell immunoglobulin like receptor gene association with tuberculosis","volume":"74","author":"Pydi","year":"2013","journal-title":"Hum Immunol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1056\/NEJMoa1013911","article-title":"Earlier versus later start of antiretroviral therapy in HIV-infected adults with uberculosis","volume":"365","author":"Blanc","year":"2011","journal-title":"N Engl J Med."},{"key":"B54","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1177\/2325957415599210","article-title":"The effect of early initiation of antiretroviral therapy in TB\/HIV-coinfected patients: a systematic review and meta-analysis","volume":"14","author":"Abay","year":"2105","journal-title":"J Int Assoc Provid AIDS Care."},{"key":"B55","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1097\/QAI.0b013e3181594c8c","article-title":"Immune reconstitution inflammatory syndrome: risk factors and treatment implications","volume":"46","author":"Manabe","year":"2007","journal-title":"J Acquir Immune Defic Syndr."},{"key":"B56","doi-asserted-by":"publisher","first-page":"e11416","DOI":"10.1371\/journal.pone.0011416","article-title":"Risk factor analyses for immune reconstitution inflammatory syndrome in a randomized study of early vs. deferred ART during an Opportunistic Infection","volume":"5","author":"Grant","year":"2010","journal-title":"PLoS ONE."},{"key":"B57","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1097\/QAD.0b013e328348fb18","article-title":"TLR2-induced cytokine responses may characterize HIV-infected patients experiencing mycobacterial immune restoration disease","volume":"25","author":"Tan","year":"2011","journal-title":"AIDS."},{"key":"B58","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.celrep.2016.05.095","article-title":"NKp80 defines a critical step during human natural killer cell development","volume":"16","author":"Freud","year":"2016","journal-title":"Cell Rep."},{"key":"B59","doi-asserted-by":"publisher","first-page":"3624","DOI":"10.1182\/blood-2005-09-3682","article-title":"Expansion of CD94\/NKG2C NK cells in response to human cytomegalovirus-infected fibroblasts","volume":"107","author":"Guma","year":"2006","journal-title":"Blood."},{"key":"B60","doi-asserted-by":"publisher","first-page":"1168","DOI":"10.1002\/eji.201546179","article-title":"Coordinated expansion of both memory T cells and NK cells in response to CMV infection in humans","volume":"46","author":"Bayard","year":"2016","journal-title":"Eur J Immunol."},{"key":"B61","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/j.it.2016.05.001","article-title":"Human adaptive natural killer cells: beyond NKG2C","volume":"37","author":"Wagner","year":"2016","journal-title":"Trends Immunol."},{"key":"B62","doi-asserted-by":"publisher","first-page":"e1007104","DOI":"10.1371\/journal.ppat.1007104","article-title":"Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques","volume":"14","author":"Ram","year":"2018","journal-title":"PLoS Pathog."},{"key":"B63","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3389\/fimmu.2018.00257","article-title":"Functional and phenotypic changes of natural killer cells in whole blood during Mycobacterium tuberculosis infection and disease","volume":"9","author":"Garand","year":"2018","journal-title":"Front Immunol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"3451","DOI":"10.4049\/jimmunol.168.7.3451","article-title":"The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium","volume":"168","author":"Vankayalapati","year":"2014","journal-title":"J Immunol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.immuni.2006.06.013","article-title":"Human NK cell education by inhibitory receptors for MHC class I","volume":"25","author":"Anfossi","year":"2006","journal-title":"Immunity."},{"key":"B66","doi-asserted-by":"publisher","first-page":"2934","DOI":"10.1002\/eji.200838760","article-title":"Beyond licensing and disarming: a quantitative view on NK-cell education","volume":"38","author":"Brodin","year":"2008","journal-title":"Eur J Immunol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.3389\/fimmu.2017.01189","article-title":"Potential role of V\u03b42+ \u03b3\u03b4T cells in regulation of immune activation in primary HIV infection","volume":"8","author":"Bhatnagar","year":"2017","journal-title":"Front Immunol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.coi.2016.06.005","article-title":"Protective immune responses of major V\u03b32V\u03b42 T-cell subset in M. tuberculosis infection","volume":"42","author":"Chen","year":"2016","journal-title":"Curr Opin Immunol."},{"key":"B69","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1126\/science.2524098","article-title":"Activation of \u03b3\u03b4 T cells in the primary immune response to Mycobacterium tuberculosis","volume":"244","author":"Janis","year":"1989","journal-title":"Science."},{"key":"B70","doi-asserted-by":"publisher","first-page":"121899","DOI":"10.1172\/jci.insight.121899","article-title":"Mucosal-associated invariant and \u03b3\u03b4 T cell subsets respond to initial Mycobacterium tuberculosis infection","volume":"3","author":"Vorkas","year":"2018","journal-title":"JCI Insight."},{"key":"B71","doi-asserted-by":"publisher","first-page":"4753","DOI":"10.4049\/jimmunol.1602019","article-title":"Adoptive transfer of phosphoantigen-specific \u03b3\u03b4 T cell subset attenuates Mycobacterium tuberculosis infection in nonhuman primates","volume":"198","author":"Qaqish","year":"2017","journal-title":"J Immunol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1038\/nri2904","article-title":"Presumed guilty: natural killer T cell defects and human disease","volume":"11","author":"Berzins","year":"2011","journal-title":"Nat Rev Immunol."},{"key":"B73","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.clim.2007.12.006","article-title":"Invariant NKT cells from HIV-1 or Mycobacterium tuberculosis-infected patients express an activated phenotype","volume":"127","author":"Montoya","year":"2008","journal-title":"Clin Immunol."},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz501","article-title":"Invariant natural killer T cell dynamics in HIV-associated tuberculosis","author":"Walker","year":"2019","journal-title":"Clin Infect Dis."},{"key":"B75","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1084\/jem.178.1.1","article-title":"Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha\/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain","volume":"178","author":"Porcelli","year":"1993","journal-title":"J Exp Med."},{"key":"B76","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1084\/jem.180.3.1171","article-title":"An invariant V alpha 24-J alpha Q\/V beta 11 T cell receptor is expressed in all individuals by clonally expanded CD4-8- T cells","volume":"180","author":"Dellabona","year":"1994","journal-title":"J Exp Med."},{"key":"B77","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/S0167-5699(00)01735-7","article-title":"NKT cells: facts, functions and fallacies","volume":"21","author":"Godfrey","year":"2000","journal-title":"Immunol Today."},{"key":"B78","first-page":"1","article-title":"Comparison of two flow cytometric methods for detection of human invariant natural killer Q18 T cells (iNKT)","volume":"7","author":"Fereidouni","year":"2010","journal-title":"Iran J Immunol."},{"key":"B79","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/0952-7915(91)90076-D","article-title":"Lymphokine-activated killer cells, natural killer cells and cytokines","volume":"3","author":"Perussia","year":"1991","journal-title":"Curr Opin Immunol."},{"key":"B80","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1089\/jir.2009.0018","article-title":"Natural killer cell-mediated cytokine response among HIV-positive south Indians with pulmonary tuberculosis","volume":"30","author":"Ramana Rao","year":"2010","journal-title":"J Interferon Cytokine Res."},{"key":"B81","doi-asserted-by":"publisher","first-page":"e0121019","DOI":"10.1371\/journal.pone.0121019","article-title":"Persistence of pathological distribution of NK cells in HIV-infected patients with prolonged use of HAART and a sustained immune response","volume":"10","author":"Frias","year":"2015","journal-title":"PLoS ONE."},{"key":"B82","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.1097\/QAD.0000000000001645","article-title":"Natural killer cells in HIV-1 infection and therapy","volume":"31","author":"Mikulak","year":"2017","journal-title":"AIDS."},{"key":"B83","doi-asserted-by":"publisher","first-page":"2174","DOI":"10.1002\/eji.200940257","article-title":"CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC","volume":"40","author":"Maggi","year":"2010","journal-title":"Eur J Immunol."},{"key":"B84","doi-asserted-by":"publisher","first-page":"486","DOI":"10.3389\/fimmu.2018.00486","article-title":"CD161 defines a functionally distinct subset of pro-inflammatory natural killer cells","volume":"9","author":"Kurioka","year":"2018","journal-title":"Front Immunol."},{"key":"B85","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1097\/00002030-200206140-00007","article-title":"Normalization of natural killer cell function and phenotype with effective anti-HIV therapy and the role of IL-10","volume":"16","author":"Parato","year":"2002","journal-title":"AIDS."},{"key":"B86","unstructured":"HIV\/AIDS 2018.2018"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01800\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,23]],"date-time":"2019-09-23T02:37:05Z","timestamp":1569206225000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01800\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,13]]},"references-count":86,"alternative-id":["10.3389\/fimmu.2019.01800"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2019.01800","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,13]]},"article-number":"1800"}}