{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T17:05:14Z","timestamp":1789232714256,"version":"build-2803163510"},"reference-count":77,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T00:00:00Z","timestamp":1566950400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2019.01996","type":"journal-article","created":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T12:46:03Z","timestamp":1566996363000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Differential Tick Salivary Protein Profiles and Human Immune Responses to Lone Star Ticks (Amblyomma americanum) From the Wild vs. a Laboratory Colony"],"prefix":"10.3389","volume":"10","author":[{"given":"L. Paulina","family":"Maldonado-Ruiz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lidia","family":"Montenegro-Cadena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany","family":"Blattner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapna","family":"Menghwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludek","family":"Zurek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berlin","family":"Londono-Renteria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,8,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"301","DOI":"10.14202\/vetworld.2015.301-315","article-title":"Tick-borne infections in human and animal population worldwide","volume":"8","author":"Brites-Neto","year":"2015","journal-title":"Vet World."},{"key":"B2","doi-asserted-by":"publisher","first-page":"281","DOI":"10.3389\/fcimb.2017.00281","article-title":"The essential role of tick salivary glands and saliva in tick feeding and pathogen transmission","volume":"7","author":"Simo","year":"2017","journal-title":"Front Cell Infect Microbiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/j.ttbdis.2018.11.005","article-title":"Wonders of tick saliva","volume":"10","author":"Nuttall","year":"2019","journal-title":"Ticks Tick Borne Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1111\/j.1365-3024.2006.00807.x","article-title":"The immunomodulatory factors of arthropod saliva and the potential for these factors to serve as vaccine targets to prevent pathogen transmission","volume":"28","author":"Titus","year":"2006","journal-title":"Parasite Immunol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jprot.2015.07.005","article-title":"Modulation of host immunity by tick saliva","volume":"128","author":"Kotal","year":"2015","journal-title":"J Proteomics."},{"key":"B6","doi-asserted-by":"publisher","first-page":"e0006410","DOI":"10.1371\/journal.pntd.0006410","article-title":"Sialome diversity of ticks revealed by RNAseq of single tick salivary glands","volume":"12","author":"Perner","year":"2018","journal-title":"PLoS Negl Trop Dis."},{"key":"B7","doi-asserted-by":"publisher","first-page":"339","DOI":"10.3389\/fcimb.2017.00339","article-title":"Tick-borne viruses and biological processes at the tick-host-virus interface","volume":"7","author":"Kazimirova","year":"2017","journal-title":"Front Cell Infect Microbiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"7852","DOI":"10.1128\/JVI.01056-15","article-title":"Tick saliva enhances powassan virus transmission to the host, influencing its dissemination and the course of disease","volume":"89","author":"Hermance","year":"2015","journal-title":"J Virol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00508-019-1500-y","article-title":"Tick saliva and its role in pathogen transmission","volume":"10","author":"Nuttall","year":"2019","journal-title":"Wien Klin Wochenschr."},{"key":"B10","doi-asserted-by":"publisher","first-page":"2888","DOI":"10.1128\/IAI.00232-08","article-title":"The tick salivary protein Salp15 inhibits the killing of serum-sensitive Borrelia burgdorferi sensu lato isolates","volume":"76","author":"Schuijt","year":"2008","journal-title":"Infect Immun."},{"key":"B11","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1590\/S0001-37652005000400008","article-title":"Haematophagous arthropod saliva and host defense system: a tale of tear and blood","volume":"77","author":"Andrade","year":"2005","journal-title":"An Acad Bras Cienc."},{"key":"B12","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1186\/s13071-016-1638-7","article-title":"Immunomodulatory effects of tick saliva on dermal cells exposed to Borrelia burgdorferi, the agent of Lyme disease","volume":"9","author":"Scholl","year":"2016","journal-title":"Parasit Vectors."},{"key":"B13","doi-asserted-by":"publisher","first-page":"337","DOI":"10.3389\/fmicb.2013.00337","article-title":"Ticks and tick-borne pathogens at the cutaneous interface: host defenses, tick countermeasures, a suitable environment for pathogen establishment","volume":"4","author":"Wikel","year":"2013","journal-title":"Front Microbiol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"572","DOI":"10.7705\/biomedica.v35i4.2530","article-title":"Aedes aegypti anti-salivary gland antibody concentration and dengue virus exposure history in healthy individuals living in an endemic area in Colombia","volume":"35","author":"Londono-Renteria","year":"2015","journal-title":"Biomedica."},{"key":"B15","doi-asserted-by":"publisher","first-page":"869","DOI":"10.4269\/ajtmh.15-0130","article-title":"Long-lasting permethrin-impregnated clothing protects against mosquito bites in outdoor workers","volume":"93","author":"Londono-Renteria","year":"2015","journal-title":"Am J Trop Med Hyg."},{"key":"B16","doi-asserted-by":"publisher","first-page":"850","DOI":"10.4269\/ajtmh.1999.61.850","article-title":"Anti-arthropod saliva antibodies among residents of a community at high risk for Lyme disease in California","volume":"61","author":"Lane","year":"1999","journal-title":"Am J Trop Med Hyg."},{"key":"B17","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3389\/fmicb.2019.00022","article-title":"Arbovirus-mosquito vector-host interactions and the impact on transmission and disease pathogenesis of arboviruses","volume":"10","author":"Huang","year":"2019","journal-title":"Front Microbiol."},{"key":"B18","first-page":"S177","article-title":"Tick-host interactions: saliva-activated transmission","volume-title":"Parasitology.","author":"Nuttall","year":"2004"},{"key":"B19","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0304-4017(03)00190-0","article-title":"Antigens from Rhipicephalus sanguineus ticks elicit potent cell-mediated immune responses in resistant but not in susceptible animals","volume":"115","author":"Ferreira","year":"2003","journal-title":"Vet Parasitol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1186\/1471-2164-15-518","article-title":"A 24\u201348 h fed Amblyomma americanum tick saliva immuno-proteome","volume":"15","author":"Radulovic","year":"2014","journal-title":"BMC Genomics."},{"key":"B21","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/0169-4758(95)80162-6","article-title":"How ticks make a living","volume":"11","author":"Ribeiro","year":"1995","journal-title":"Parasitol Today."},{"key":"B22","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1756-3305-7-77","article-title":"ANTIDotE: anti-tick vaccines to prevent tick-borne diseases in Europe","volume":"7","author":"Sprong","year":"2014","journal-title":"Parasit Vectors."},{"key":"B23","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1146\/annurev.ento.48.091801.112728","article-title":"The ascendancy of Amblyomma americanum as a vector of pathogens affecting humans in the United States","volume":"48","author":"Childs","year":"2003","journal-title":"Annu Rev Entomol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1093\/jme\/tju026","article-title":"County scale distribution of Amblyomma americanum (Ixodida: Ixodidae) in Oklahoma: addressing local deficits in tick maps based on passive reporting","volume":"52","author":"Barrett","year":"2015","journal-title":"J Med Entomol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"e0209082","DOI":"10.1371\/journal.pone.0209082","article-title":"Current and future distribution of the Lone Star Tick, Amblyomma americanum (L.) (Acari: Ixodidae) in North America","volume":"14","author":"Raghavan","year":"2019","journal-title":"PLoS ONE."},{"key":"B26","doi-asserted-by":"publisher","first-page":"e0130513","DOI":"10.1371\/journal.pone.0130513","article-title":"Amblyomma americanum as a bridging vector for human infection with Francisella tularensis","volume":"10","author":"Mani","year":"2015","journal-title":"PLoS ONE."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1056","DOI":"10.3389\/fimmu.2019.01056","article-title":"Discovery of alpha-gal-containing antigens in north american tick species believed to induce red meat allergy","volume":"10","author":"Crispell","year":"2019","journal-title":"Front Immunol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1093\/gbe\/evw080","article-title":"Population and evolutionary genomics of Amblyomma americanum, an expanding arthropod disease vector","volume":"8","author":"Monzon","year":"2016","journal-title":"Genome Biol Evol."},{"key":"B29","unstructured":"20521734Tickborne diseases of the United States2019"},{"key":"B30","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/B978-012510451-7\/50026-8","article-title":"Ticks (Ixodida)","volume-title":"Medical and Veterinary Entomology","author":"Sonenshine","year":"2002"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1603\/ME09240","article-title":"Antibody response against Anopheles albimanus (Diptera: Culicidae) salivary protein as a measure of mosquito bite exposure in Haiti","volume":"47","author":"Londono-Renteria","year":"2010","journal-title":"J Med Entomol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1186\/s13071-015-1160-3","article-title":"An. gambiae gSG6-P1 evaluation as a proxy for human-vector contact in the Americas: a pilot study","volume":"8","author":"Londono-Renteria","year":"2015","journal-title":"Parasit Vectors."},{"key":"B33","doi-asserted-by":"publisher","first-page":"e0004941","DOI":"10.1371\/journal.pntd.0004941","article-title":"Aedes aegypti D7 saliva protein inhibits dengue virus infection","volume":"10","author":"Conway","year":"2016","journal-title":"PLoS Negl Trop Dis."},{"key":"B34","doi-asserted-by":"publisher","first-page":"e0006439","DOI":"10.1371\/journal.pntd.0006439","article-title":"Mosquito saliva alone has profound effects on the human immune system","volume":"12","author":"Vogt","year":"2018","journal-title":"PLoS Negl Trop Dis."},{"key":"B35","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1590\/s1984-296120180098","article-title":"Antitumoral effects of Amblyomma sculptum Berlese saliva in neuroblastoma cell lines involve cytoskeletal deconstruction and cell cycle arrest","volume":"28","author":"T.Nascimento","year":"2019","journal-title":"Rev Bras Parasitol Vet."},{"key":"B36","first-page":"e00958","article-title":"Differentiated human SH-SY5Y cells provide a reductionist model of herpes simplex virus 1 neurotropism","volume-title":"J Virol.","author":"Shipley","year":"2017"},{"key":"B37","doi-asserted-by":"publisher","first-page":"e115107","DOI":"10.1371\/journal.pone.0115107","article-title":"Thrombospondin-1 production is enhanced by Porphyromonas gingivalis lipopolysaccharide in THP-1 cells","volume":"9","author":"Gokyu","year":"2014","journal-title":"PLoS ONE."},{"key":"B38","doi-asserted-by":"publisher","first-page":"10473","DOI":"10.18632\/oncotarget.2242","article-title":"Thymidine phosphorylase activates NFkappaB and stimulates the expression of angiogenic and metastatic factors in human cancer cells","volume":"5","author":"Tabata","year":"2014","journal-title":"Oncotarget."},{"key":"B39","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1136\/jclinpath-2011-200567","article-title":"Decreased Toll-interacting protein and peroxisome proliferator-activated receptor gamma are associated with increased expression of Toll-like receptors in colon carcinogenesis","volume":"65","author":"Pimentel-Nunes","year":"2012","journal-title":"J Clin Pathol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"734","DOI":"10.3892\/ijmm.2017.2885","article-title":"Resveratrol inhibits the IL-1beta-induced expression of MMP-13 and IL-6 in human articular chondrocytes via TLR4\/MyD88-dependent and -independent signaling cascades","volume":"39","author":"Gu","year":"2017","journal-title":"Int J Mol Med"},{"key":"B41","doi-asserted-by":"publisher","first-page":"e004440","DOI":"10.1161\/JAHA.116.004440","article-title":"Nkx2-5 is expressed in atherosclerotic plaques and attenuates development of atherosclerosis in apolipoprotein E-deficient mice","volume":"5","author":"Du","year":"2016","journal-title":"J Am Heart Assoc."},{"key":"B42","doi-asserted-by":"publisher","first-page":"66878","DOI":"10.18632\/oncotarget.19916","article-title":"Establishment of a neuroendocrine prostate cancer model driven by the RNA splicing factor SRRM4","volume":"8","author":"Li","year":"2017","journal-title":"Oncotarget."},{"key":"B43","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1186\/s12967-018-1655-8","article-title":"Plasma interleukin-37 is increased and inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells in systemic juvenile idiopathic arthritis patients","volume":"16","author":"Feng","year":"2018","journal-title":"J Transl Med."},{"key":"B44","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1159\/000447483","article-title":"The role of high mobility group box 1 protein in interleukin-18-induced myofibroblastic transition of valvular interstitial cells","volume":"135","author":"Wang","year":"2016","journal-title":"Cardiology."},{"key":"B45","doi-asserted-by":"publisher","first-page":"590654","DOI":"10.1155\/2014\/590654","article-title":"Regulation of chemokine CCL5 synthesis in human peritoneal fibroblasts: a key role of IFN-gamma","volume":"2014","author":"Kawka","year":"2014","journal-title":"Mediators Inflamm."},{"key":"B46","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.jim.2016.01.005","article-title":"Development of a multiplex quantitative PCR assay for the analysis of human cytokine gene expression in influenza A virus-infected cells","volume":"430","author":"Plotnikova","year":"2016","journal-title":"J Immunol Methods."},{"key":"B47","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.diagmicrobio.2012.09.015","article-title":"Interferon gamma mRNA quantitative real-time polymerase chain reaction for the diagnosis of latent tuberculosis: a novel interferon gamma release assay","volume":"75","author":"Kim","year":"2013","journal-title":"Diagn Microbiol Infect Dis."},{"key":"B48","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1093\/molbev\/msg079","article-title":"Exon-intron structure and evolution of the Lipocalin gene family","volume":"20","author":"Sanchez","year":"2003","journal-title":"Mol Biol Evol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/S0167-4838(00)00168-0","article-title":"Tick histamine-binding proteins: lipocalins with a second binding cavity","volume":"1482","author":"Paesen","year":"2000","journal-title":"Biochim Biophys Acta."},{"key":"B50","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1111\/bjd.15424","article-title":"Lipocalin-2 is expressed by activated granulocytes and keratinocytes in affected skin and reflects disease activity in acne inversa\/hidradenitis suppurativa","volume":"177","author":"Wolk","year":"2017","journal-title":"Br J Dermatol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1186\/1756-3305-4-187","article-title":"Implication of haematophagous arthropod salivary proteins in host-vector interactions","volume":"4","author":"Fontaine","year":"2011","journal-title":"Parasit Vectors."},{"key":"B52","doi-asserted-by":"publisher","first-page":"e81211","DOI":"10.1371\/journal.pone.0081211","article-title":"Use of anti-Aedes aegypti salivary extract antibody concentration to correlate risk of vector exposure and dengue transmission risk in Colombia","volume":"8","author":"Londono-Renteria","year":"2013","journal-title":"PLoS ONE."},{"key":"B53","doi-asserted-by":"publisher","first-page":"e29107","DOI":"10.1371\/journal.pone.0029107","article-title":"Relationship between exposure to vector bites and antibody responses to mosquito salivary gland extracts","volume":"6","author":"Fontaine","year":"2011","journal-title":"PLoS ONE."},{"key":"B54","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1186\/s13071-019-3468-x","article-title":"Counterattacking the tick bite: towards a rational design of anti-tick vaccines targeting pathogen transmission","volume":"12","author":"Rego","year":"2019","journal-title":"Parasit Vectors."},{"key":"B55","doi-asserted-by":"publisher","first-page":"e0131292","DOI":"10.1371\/journal.pone.0131292","article-title":"An insight into the sialome of the lone star tick, Amblyomma americanum, with a glimpse on its time dependent gene expression","volume":"10","author":"Karim","year":"2015","journal-title":"PLoS ONE."},{"key":"B56","doi-asserted-by":"publisher","first-page":"2844","DOI":"10.1016\/S0264-410X(03)00167-1","article-title":"A serine proteinase inhibitor (serpin) from ixodid tick Haemaphysalis longicornis; cloning and preliminary assessment of its suitability as a candidate for a tick vaccine","volume":"21","author":"Sugino","year":"2003","journal-title":"Vaccine."},{"key":"B57","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.ttbdis.2018.01.008","article-title":"Proteomic profiling of the midgut contents of Haemaphysalis flava","volume":"9","author":"Liu","year":"2018","journal-title":"Ticks Tick Borne Dis."},{"key":"B58","doi-asserted-by":"publisher","first-page":"e94831","DOI":"10.1371\/journal.pone.0094831","article-title":"Proteomic analysis of cattle tick Rhipicephalus (Boophilus) microplus saliva: a comparison between partially and fully engorged females","volume":"9","author":"Tirloni","year":"2014","journal-title":"PLoS ONE."},{"key":"B59","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.ttbdis.2015.03.012","article-title":"Identification of 24h ixodes scapularis immunogenic tick saliva proteins","volume":"6","author":"Lewis","year":"2015","journal-title":"Ticks Tick Borne Dis."},{"key":"B60","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1073\/pnas.82.1.9","article-title":"Common evolutionary origin of alpha 2-macroglobulin and complement components C3 and C4","volume":"82","author":"Sottrup-Jensen","year":"1985","journal-title":"Proc Natl Acad Sci USA."},{"key":"B61","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1093\/jme\/tjw003","article-title":"Human C5a protein participates in the mosquito immune response against dengue virus","volume":"53","author":"Londono-Renteria","year":"2016","journal-title":"J Med Entomol."},{"key":"B62","doi-asserted-by":"publisher","first-page":"36584","DOI":"10.1074\/jbc.M007344200","article-title":"HeLp, a heme lipoprotein from the hemolymph of the cattle tick, Boophilus microplus","volume":"275","author":"Maya-Monteiro","year":"2000","journal-title":"J Biol Chem."},{"key":"B63","doi-asserted-by":"publisher","first-page":"E133","DOI":"10.3390\/toxins8050133","article-title":"An immunosuppressant peptide from the hard tick Amblyomma variegatum","volume":"8","author":"Tian","year":"2016","journal-title":"Toxins."},{"key":"B64","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1093\/jmedent\/29.5.818","article-title":"Modulation of host-immune responses by ticks (Acari: Ixodidae): effect of salivary gland extracts on host macrophages and lymphocyte cytokine production","volume":"29","author":"Ramachandra","year":"1992","journal-title":"J Med Entomol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"e3941","DOI":"10.1371\/journal.pone.0003941","article-title":"Ixodes ricinus tick lipocalins: identification, cloning, phylogenetic analysis and biochemical characterization","volume":"3","author":"Beaufays","year":"2008","journal-title":"PLoS ONE."},{"key":"B66","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1093\/molbev\/msg126","article-title":"The major tick salivary gland proteins and toxins from the soft tick, Ornithodoros savignyi, are part of the tick Lipocalin family: implications for the origins of tick toxicoses","volume":"20","author":"Mans","year":"2003","journal-title":"Mol Biol Evol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"279","DOI":"10.4049\/jimmunol.1003964","article-title":"A molecular mechanism for TNF-alpha-mediated downregulation of B cell responses","volume":"188","author":"Frasca","year":"2012","journal-title":"J Immunol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1006\/meth.1996.0396","article-title":"Tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in B-lymphocyte function","volume":"11","author":"Rieckmann","year":"1997","journal-title":"Methods."},{"key":"B69","doi-asserted-by":"publisher","first-page":"28188","DOI":"10.1038\/srep28188","article-title":"TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation","volume":"6","author":"Liu","year":"2016","journal-title":"Sci Rep."},{"key":"B70","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1002\/path.4565","article-title":"Tollip is a critical mediator of cerebral ischaemia-reperfusion injury","volume":"237","author":"Li","year":"2015","journal-title":"J Pathol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1007\/s11011-016-9801-6","article-title":"Neuron specific enolase: a promising therapeutic target in acute spinal cord injury","volume":"31","author":"Haque","year":"2016","journal-title":"Metab Brain Dis."},{"key":"B72","first-page":"17","article-title":"Tick paralysis","volume":"72","author":"Borawski","year":"2018","journal-title":"Przegl Epidemiol."},{"key":"B73","doi-asserted-by":"publisher","first-page":"E53","DOI":"10.3390\/vetsci5020053","article-title":"Tick paralysis: solving an enigma","volume":"5","author":"Pienaar","year":"2018","journal-title":"Vet Sci."},{"key":"B74","first-page":"53193","article-title":"Differentiation of the SH-SY5Y human neuroblastoma cell line","volume-title":"J Vis Exp.","author":"Shipley","year":"2016"},{"key":"B75","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1093\/jmedent\/47.2.152","article-title":"Population genetics of Amblyomma americanum (Acari: Ixodidae) collected from Arkansas","volume":"47","author":"Trout","year":"2010","journal-title":"J Med Entomol."},{"key":"B76","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1016\/j.tree.2008.06.017","article-title":"Life history determines genetic structure and evolutionary potential of host-parasite interactions","volume":"23","author":"Barrett","year":"2008","journal-title":"Trends Ecol Evol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"e0208455","DOI":"10.1371\/journal.pone.0208455","article-title":"IgG1 and IgG4 antibodies against Aedes aegypti salivary proteins and risk for dengue infections","volume":"14","author":"Cardenas","year":"2019","journal-title":"PLoS ONE."}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01996\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T12:46:07Z","timestamp":1566996367000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.01996\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,28]]},"references-count":77,"alternative-id":["10.3389\/fimmu.2019.01996"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2019.01996","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.737869282.793574186","asserted-by":"object"}]},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,28]]},"article-number":"1996"}}