{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:04:41Z","timestamp":1790352281977,"version":"4.1.0"},"reference-count":67,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T00:00:00Z","timestamp":1574208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2019.02449","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T04:45:08Z","timestamp":1574225108000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":49,"title":["Inhibition of miR-378a-3p by Inflammation Enhances IL-33 Levels: A Novel Mechanism of Alarmin Modulation in Ulcerative Colitis"],"prefix":"10.3389","volume":"10","author":[{"given":"Karen","family":"Dubois-Camacho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Diaz-Jimenez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjorie","family":"De la Fuente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Quera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Simian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maripaz","family":"Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glauben","family":"Landskron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio","family":"Olivares-Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Cidlowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangping","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon\u00e1s","family":"Chnaiderman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Soto-Rifo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda-Julieta","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Calixto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela A.","family":"Hermoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1606","DOI":"10.1016\/S0140-6736(12)60150-0","article-title":"Ulcerative colitis","volume":"380","author":"Ord\u00e1s","year":"2012","journal-title":"Lancet."},{"key":"B2","doi-asserted-by":"publisher","first-page":"6628","DOI":"10.3748\/wjg.v23.i36.6628","article-title":"Glucocorticosteroid therapy in inflammatory bowel diseases: from clinical practice to molecular biology","volume":"23","author":"Dubois-Camacho","year":"2017","journal-title":"World J Gastroenterol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1256","DOI":"10.1038\/ismej.2013.80","article-title":"Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis","volume":"7","author":"Rigottier-Gois","year":"2013","journal-title":"ISME J."},{"key":"B4","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/S0016-5085(99)70126-5","article-title":"Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis","volume":"116","author":"Schmitz","year":"1999","journal-title":"Gastroenterology."},{"key":"B5","doi-asserted-by":"publisher","first-page":"15823","DOI":"10.1073\/pnas.0707421104","article-title":"Ulcerative colitis and autoimmunity induced by loss of myeloid v integrins","volume":"104","author":"Lacy-Hulbert","year":"2007","journal-title":"Proc Natl Acad Sci USA."},{"key":"B6","doi-asserted-by":"publisher","first-page":"7390","DOI":"10.4049\/jimmunol.181.10.7390","article-title":"Intestinal macrophage\/epithelial cell-derived CCL11\/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis","volume":"181","author":"Ahrens","year":"2008","journal-title":"J Immunol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1080\/00365520701409035","article-title":"Tissue levels of tumor necrosis factor-alpha correlates with grade of inflammation in untreated ulcerative colitis","volume":"42","author":"Olsen","year":"2007","journal-title":"Scand J Gastroenterol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1053\/j.gastro.2011.02.016","article-title":"Pro-inflammatory cytokines in the pathogenesis of IBD","volume":"140","author":"Strober","year":"2011","journal-title":"Gastroenterology."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1097","DOI":"10.1002\/ibd.21175","article-title":"Characterization of the novel ST2\/IL-33 system in patients with inflammatory bowel disease","volume":"16","author":"Beltr\u00e1n","year":"2010","journal-title":"Inflamm Bowel Dis."},{"key":"B10","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1007\/s00535-014-0982-7","article-title":"IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis","volume":"50","author":"Seidelin","year":"2014","journal-title":"J Gastroenterol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.imlet.2009.11.001","article-title":"IL-33 is upregulated in colonocytes of ulcerative colitis","volume":"128","author":"Seidelin","year":"2010","journal-title":"Immunol Lett."},{"key":"B12","doi-asserted-by":"publisher","first-page":"8017","DOI":"10.1073\/pnas.0912678107","article-title":"Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1\/Th2 driven enteritis","volume":"107","author":"Pastorelli","year":"2010","journal-title":"Proc Natl Acad Sci USA."},{"key":"B13","doi-asserted-by":"publisher","first-page":"35403","DOI":"10.1038\/srep35403","article-title":"Loss of interleukin 33 expression in colonic crypts-a potential marker for disease remission in ulcerative colitis","volume":"6","author":"Gundersen","year":"2016","journal-title":"Sci Rep."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2018\/1827901","article-title":"IL-33 protects mice against DSS-induced chronic colitis by increasing both regulatory B cell and regulatory T cell responses as well as decreasing Th17 cell response","volume":"2018","author":"Zhu","year":"2018","journal-title":"J Immunol Res."},{"key":"B15","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1038\/s41385-019-0153-5","article-title":"The alarmins IL-1 and IL-33 differentially regulate the functional specialisation of Foxp3 + regulatory T cells during mucosal inflammation","volume":"12","author":"Alvarez","year":"2019","journal-title":"Mucosal Immunol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1038\/s41598-017-00840-2","article-title":"Interleukin-33 regulates intestinal inflammation by modulating macrophages in inflammatory bowel disease","volume":"7","author":"Seo","year":"2017","journal-title":"Sci Rep."},{"key":"B17","doi-asserted-by":"publisher","first-page":"E9362","DOI":"10.1073\/pnas.1803613115","article-title":"IL-33 promotes recovery from acute colitis by inducing miR-320 to stimulate epithelial restitution and repair","volume":"115","author":"Lopetuso","year":"2018","journal-title":"Proc Natl Acad Sci USA."},{"key":"B18","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1038\/nrg2290","article-title":"Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?","volume":"9","author":"Filipowicz","year":"2008","journal-title":"Nat Rev Genet."},{"key":"B19","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1101\/gad.1184404","article-title":"Specificity of microRNA target selection in translational repression","volume":"18","author":"Doench","year":"2004","journal-title":"Genes Dev."},{"key":"B20","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1016\/j.gde.2011.04.003","article-title":"MicroRNAs and developmental timing","volume":"21","author":"Ambros","year":"2011","journal-title":"Curr Opin Genet Dev."},{"key":"B21","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1038\/s41580-018-0045-7","article-title":"Regulation of microRNA function in animals","volume":"20","author":"Gebert","year":"2019","journal-title":"Nat Rev Mol Cell Biol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.coph.2017.10.010","article-title":"MicroRNAs in intestinal barrier function, inflammatory bowel disease and related cancers\u2014their effects and therapeutic potentials","volume":"37","author":"Tili","year":"2017","journal-title":"Curr Opin Pharmacol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1053\/j.gastro.2008.07.068","article-title":"MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory Peptide-2\u03b1","volume":"135","author":"Wu","year":"2008","journal-title":"Gastroenterology."},{"key":"B24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12865-015-0069-0","article-title":"MicroRNA signatures differentiate Crohn's disease from ulcerative colitis","volume":"16","author":"Schaefer","year":"2015","journal-title":"BMC Immunol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"5818","DOI":"10.3748\/wjg.v20.i19.5818","article-title":"MicroRNAs: new therapeutic targets for intestinal barrier dysfunction","volume":"20","author":"Zhang","year":"2014","journal-title":"World J Gastroenterol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"S129","DOI":"10.1111\/j.1440-1746.2009.06216.x","article-title":"Increased expression of microRNA in the inflamed colonic mucosa of patients with active ulcerative colitis","volume":"25","author":"Takagi","year":"2010","journal-title":"J Gastroenterol Hepatol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1371\/journal.pone.0013160","article-title":"Identification of restricted subsets of mature microRNA abnormally expressed in inactive colonic mucosa of patients with inflammatory bowel disease: commentary","volume":"11","author":"Balzola","year":"2011","journal-title":"Inflamm Bowel Dis Monit."},{"key":"B28","doi-asserted-by":"publisher","first-page":"4629","DOI":"10.3748\/wjg.v18.i34.4629","article-title":"MicroRNAs in inflammatory bowel disease - pathogenesis, diagnostics and therapeutics","volume":"18","author":"Coskun","year":"2012","journal-title":"World J Gastroenterol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"30824","DOI":"10.1038\/srep30824","article-title":"MicroRNA-16 is putatively involved in the NF-\u03ba B pathway regulation in ulcerative colitis through adenosine A2a receptor (A2aAR) mRNA targeting","volume":"6","author":"Tian","year":"2016","journal-title":"Sci Rep."},{"key":"B30","doi-asserted-by":"publisher","first-page":"E85","DOI":"10.3390\/genes9020085","article-title":"MicroRNA-31 and MicroRNA-155 are overexpressed in ulcerative colitis and regulate IL-13 signaling by targeting interleukin 13 receptor \u03b1-1","volume":"9","author":"Gwiggner","year":"2018","journal-title":"Genes (Basel)."},{"key":"B31","doi-asserted-by":"publisher","first-page":"W435","DOI":"10.1093\/nar\/gkx279","article-title":"IntaRNA 2.0: enhanced and customizable prediction of RNA-RNA interactions","volume":"45","author":"Mann","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"B32","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1748-7188-6-26","article-title":"ViennaRNA Package 2","volume":"6","author":"Lorenz","year":"2011","journal-title":"Algorithms Mol Biol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.7554\/eLife.05005","article-title":"Predicting effective microRNA target sites in mammalian mRNAs","volume":"4","author":"Agarwal","year":"2015","journal-title":"Elife."},{"key":"B34","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1055\/s-0034-1397352","article-title":"AAV-mediated miRNA delivery and therapeutics","volume":"35","author":"Xie","year":"2015","journal-title":"Semin Liver Dis."},{"key":"B35","doi-asserted-by":"publisher","first-page":"2008","DOI":"10.1002\/hep.27671","article-title":"Recombinant adeno-associated virus-mediated inhibition of microRNA-21 protects mice against the lethal schistosome infection by repressing both IL-13 and transforming growth factor beta 1 pathways","volume":"61","author":"He","year":"2015","journal-title":"Hepatology."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1426","DOI":"10.1007\/s10620-017-4567-1","article-title":"Role of MiRNAs in inflammatory bowel disease","volume":"62","author":"Cao","year":"2017","journal-title":"Dig Dis Sci."},{"key":"B37","doi-asserted-by":"publisher","first-page":"3421","DOI":"10.4049\/jimmunol.1502081","article-title":"MicroRNA-487b is a negative regulator of macrophage activation by targeting IL-33 production","volume":"196","author":"Xiang","year":"2016","journal-title":"J Immunol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"D135","DOI":"10.1093\/nar\/gkj135","article-title":"miRNAMap: genomic maps of microRNA genes and their target genes in mammalian genomes","volume":"34","author":"Hsu","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"B39","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1007\/s005350200048","article-title":"Increased expression of tumor necrosis factor-\u03b1 messenger RNA in the intestinal mucosa of inflammatory bowel disease, particularly in patients with disease in the inactive phase","volume":"37","author":"Akazawa","year":"2002","journal-title":"J Gastroenterol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"21","DOI":"10.4049\/jimmunol.0902369","article-title":"Cutting edge: TNF-induced MicroRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation","volume":"184","author":"Su\u00e1rez","year":"2010","journal-title":"J Immunol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1186\/s13046-018-0839-7","article-title":"IL-33 facilitates proliferation of colorectal cancer dependent on COX2\/PGE 2","volume":"37","author":"Li","year":"2018","journal-title":"J Exp Clin Cancer Res."},{"key":"B42","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.1161\/CIRCULATIONAHA.111.087817","article-title":"A novel regulator of macrophage activation: MiR-223 in obesity-associated adipose tissue inflammation","volume":"125","author":"Zhuang","year":"2012","journal-title":"Circulation."},{"key":"B43","doi-asserted-by":"publisher","first-page":"15819","DOI":"10.1073\/pnas.0901216106","article-title":"miR-147, a microRNA that is induced upon Toll-like receptor stimulation, regulates murine macrophage inflammatory responses","volume":"106","author":"Liu","year":"2009","journal-title":"Proc Natl Acad Sci USA."},{"key":"B44","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1186\/s12935-017-0461-3","article-title":"miR-422a inhibits cell proliferation in colorectal cancer by targeting AKT1 and MAPK1","volume":"17","author":"Wei","year":"2017","journal-title":"Cancer Cell Int."},{"key":"B45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2015\/281756","article-title":"The role of miR-378a in metabolism, angiogenesis, and muscle biology","volume":"2015","author":"Krist","year":"2015","journal-title":"Int J Endocrinol."},{"key":"B46","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1038\/s41419-018-0564-3","article-title":"MiR-422a regulates cellular metabolism and malignancy by targeting pyruvate dehydrogenase kinase 2 in gastric cancer article","volume":"9","author":"He","year":"2018","journal-title":"Cell Death Dis."},{"key":"B47","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1097\/MIB.0000000000000011","article-title":"Metabolic alterations to the mucosal microbiota in inflammatory bowel disease","volume":"20","author":"Davenport","year":"2014","journal-title":"Inflamm Bowel Dis."},{"key":"B48","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1080\/15476286.2016.1239008","article-title":"miR-378a-3p promotes differentiation and inhibits proliferation of myoblasts by targeting HDAC4 in skeletal muscle development","volume":"13","author":"Wei","year":"2016","journal-title":"RNA Biol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"13170","DOI":"10.1038\/srep13170","article-title":"miR-378a-3p modulates tamoxifen sensitivity in breast cancer MCF-7 cells through targeting GOLT1A","volume":"5","author":"Ikeda","year":"2015","journal-title":"Sci Rep."},{"key":"B50","doi-asserted-by":"publisher","first-page":"1808","DOI":"10.1016\/j.ymthe.2018.04.016","article-title":"Posttranscriptional regulation of interleukin-33 expression by MicroRNA-200 in bronchial asthma","volume":"26","author":"Tang","year":"2018","journal-title":"Mol Ther."},{"key":"B51","doi-asserted-by":"publisher","first-page":"6774","DOI":"10.1038\/ncomms7774","article-title":"MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease","volume":"6","author":"Millar","year":"2015","journal-title":"Nat Commun."},{"key":"B52","first-page":"30","article-title":"Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental TH1\/TH2 driven enteritis: commentary","volume":"11","author":"Balzola","year":"2010","journal-title":"Inflamm Bowel Dis Monit."},{"key":"B53","doi-asserted-by":"publisher","first-page":"10943","DOI":"10.1038\/s41598-017-11487-4","article-title":"MicroRNA profiling reveals distinct profiles for tissue-derived and cultured endothelial cells","volume":"7","author":"Kuosmanen","year":"2017","journal-title":"Sci Rep."},{"key":"B54","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1111\/jcmm.12951","article-title":"The role of microRNAs in intrahepatic cholangiocarcinoma","volume":"21","author":"Li","year":"2017","journal-title":"J Cell Mol Med."},{"key":"B55","doi-asserted-by":"publisher","first-page":"e83571","DOI":"10.1371\/journal.pone.0083571","article-title":"MiR-133b Is down-regulated in human osteosarcoma and inhibits osteosarcoma cells proliferation, migration and invasion, and promotes apoptosis","volume":"8","author":"Zhao","year":"2013","journal-title":"PLoS ONE."},{"key":"B56","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1186\/s12864-016-3090-7","article-title":"microRNA analysis of gastric cancer patients from Saudi Arabian population","volume":"17","author":"Bibi","year":"2016","journal-title":"BMC Genomics."},{"key":"B57","doi-asserted-by":"publisher","first-page":"e0193625","DOI":"10.1371\/journal.pone.0193625","article-title":"Identification of a microRNA signature associated with survivability in cervical squamous cell carcinoma","volume":"13","author":"Ma","year":"2018","journal-title":"PLoS ONE."},{"key":"B58","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1093\/gbe\/evw092","article-title":"Evolutionary transitions of microrna-target pairs","volume":"8","author":"Nozawa","year":"2016","journal-title":"Genome Biol Evol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"e115241","DOI":"10.1371\/journal.pone.0115241","article-title":"Functional and evolutionary significance of human microRNA seed region mutations","volume":"9","author":"Hill","year":"2014","journal-title":"PLoS ONE."},{"key":"B60","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1002\/iub.1317","article-title":"MicroRNA-378 inhibits cell growth and enhances l -OHP-induced apoptosis in human colorectal cancer","volume":"66","author":"Wang","year":"2014","journal-title":"IUBMB Life."},{"key":"B61","doi-asserted-by":"publisher","first-page":"3937","DOI":"10.3748\/wjg.14.3937","article-title":"Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategies","volume":"14","author":"Lakatos","year":"2008","journal-title":"World J Gastroenterol."},{"key":"B62","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2014\/149185","article-title":"Chronic inflammation and cytokines in the tumor microenvironment","volume":"2014","author":"Landskron","year":"2014","journal-title":"J Immunol Res."},{"key":"B63","doi-asserted-by":"publisher","first-page":"4175","DOI":"10.1007\/s11033-019-04868-7","article-title":"Novel miRNAs as potential biomarkers in stage II colon cancer: microarray analysis","volume":"46","author":"Gungormez","year":"2019","journal-title":"Mol Biol Rep."},{"key":"B64","doi-asserted-by":"publisher","first-page":"15330","DOI":"10.1073\/pnas.1207605109","article-title":"Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378*","volume":"109","author":"Carrer","year":"2012","journal-title":"Proc Natl Acad Sci USA."},{"key":"B65","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1093\/abbs\/gmr007","article-title":"PGC-1 coactivators in the control of energy metabolism","volume":"43","author":"Liu","year":"2011","journal-title":"Acta Biochim Biophys Sin."},{"key":"B66","doi-asserted-by":"publisher","first-page":"E4523","DOI":"10.1073\/pnas.1415279111","article-title":"PGC-1\u03b2 promotes enterocyte lifespan and tumorigenesis in the intestine","volume":"111","author":"Bellafante","year":"2014","journal-title":"Proc Natl Acad Sci USA."},{"key":"B67","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1007\/s11010-010-0474-x","article-title":"Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis","volume":"342","author":"Sifroni","year":"2010","journal-title":"Mol Cell Biochem."}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.02449\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T04:45:13Z","timestamp":1574225113000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.02449\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,20]]},"references-count":67,"alternative-id":["10.3389\/fimmu.2019.02449"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2019.02449","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,20]]},"article-number":"2449"}}