{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:06:21Z","timestamp":1790751981355,"version":"4.1.0"},"reference-count":78,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T00:00:00Z","timestamp":1571788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2019.02484","type":"journal-article","created":{"date-parts":[[2019,10,23]],"date-time":"2019-10-23T17:11:47Z","timestamp":1571850707000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":23,"title":["Gut Antibody Deficiency in a Mouse Model of CVID Results in Spontaneous Development of a Gluten-Sensitive Enteropathy"],"prefix":"10.3389","volume":"10","author":[{"given":"Ahmed Dawood","family":"Mohammed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. A. Wadud","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioulia","family":"Chatzistamou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douja","family":"Chamseddine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katie","family":"Williams-Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mason","family":"Perry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reilly","family":"Enos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregorio","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Aladhami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole A.","family":"Oskeritzian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Jolly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuqian","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zui","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason L.","family":"Kubinak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2019,10,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1038\/nri3466","article-title":"Primary antibody deficiencies","volume":"13","author":"Durandy","year":"2013","journal-title":"Nat Rev Immunol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e1181","DOI":"10.1016\/j.jaci.2015.04.049","article-title":"Practice parameter for the diagnosis and management of primary immunodeficiency","volume":"136","author":"Bonilla","year":"2015","journal-title":"J Allergy Clin Immunol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1136\/jcp.54.5.337","article-title":"IgA deficiency: what we should-or should not-be doing","volume":"54","author":"Lilic","year":"2001","journal-title":"J Clin Pathol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1023\/A:1012241117984","article-title":"Physiology of IgA and IgA deficiency","volume":"21","author":"Cunningham-Rundles","year":"2001","journal-title":"J Clin Immunol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1182\/asheducation-2012.1.301","article-title":"The many faces of common variable immunodeficiency","volume":"2012","author":"Cunningham-Rundles","year":"2012","journal-title":"Hematol Am Soc Hematol Educ Program."},{"key":"B6","doi-asserted-by":"publisher","first-page":"537","DOI":"10.2174\/1871530318666180413110216","article-title":"The clinical and immunological features of patients with primary antibody deficiencies","volume":"18","author":"Azizi","year":"2018","journal-title":"Endocr Metab Immune Disord Drug Targets"},{"key":"B7","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s11894-016-0491-3","article-title":"Gastrointestinal Disorders Associated with Common Variable Immune Deficiency (CVID) and Chronic Granulomatous Disease (CGD)","volume":"18","author":"Uzzan","year":"2016","journal-title":"Curr Gastroenterol Rep."},{"key":"B8","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1042\/bst0250475","article-title":"The polymeric immunoglobulin receptor: structure and synthesis","volume":"25","author":"Kaetzel","year":"1997","journal-title":"Biochem Soc Trans."},{"key":"B9","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1111\/j.0105-2896.2005.00278.x","article-title":"The polymeric immunoglobulin receptor: bridging innate and adaptive immune responses at mucosal surfaces","volume":"206","author":"Kaetzel","year":"2005","journal-title":"Immunol Rev."},{"key":"B10","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/S1074-7613(02)00341-2","article-title":"Secretory component: a new role in secretory IgA-mediated immune exclusion in vivo","volume":"17","author":"Phalipon","year":"2002","journal-title":"Immunity."},{"key":"B11","doi-asserted-by":"publisher","first-page":"383","DOI":"10.3109\/08820131003622635","article-title":"Secretory IgA: arresting microbial pathogens at epithelial borders","volume":"39","author":"Mantis","year":"2010","journal-title":"Immunol Invest."},{"key":"B12","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1038\/mi.2011.41","article-title":"Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut","volume":"4","author":"Mantis","year":"2011","journal-title":"Mucosal Immunol."},{"key":"B13","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1038\/nri.2016.114","article-title":"Do antibodies select a healthy microbiota?","volume":"16","author":"Kubinak","year":"2016","journal-title":"Nat Rev Immunol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1038\/mi.2016.18","article-title":"Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation","volume":"9","author":"J\u00f8rgensen","year":"2016","journal-title":"Mucosal Immunol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.autrev.2012.10.017","article-title":"Chipping away at a mountain: genomic studies in common variable immunodeficiency","volume":"12","author":"Keller","year":"2013","journal-title":"Autoimmun Rev."},{"key":"B16","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/B978-0-12-385991-4.00002-7","article-title":"\u201cA rose is a rose is a rose,\u201d but CVID is Not CVID common variable immune deficiency (CVID), what do we know in 2011?","volume":"111","author":"Yong","year":"2011","journal-title":"Adv Immunol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1360","DOI":"10.1016\/j.jaci.2011.02.039","article-title":"Genome-wide association identifies diverse causes of common variable immunodeficiency","volume":"127","author":"Orange","year":"2011","journal-title":"J Allergy Clin Immunol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1038\/376352a0","article-title":"Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice","volume":"376","author":"Rickert","year":"1995","journal-title":"Nature."},{"key":"B19","doi-asserted-by":"publisher","first-page":"3112","DOI":"10.4049\/jimmunol.1202098","article-title":"Reduced T-dependent humoral immunity in CD20-deficient mice","volume":"191","author":"Morsy","year":"2013","journal-title":"J Immunol."},{"key":"B20","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.chom.2014.12.009","article-title":"MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health","volume":"17","author":"Kubinak","year":"2015","journal-title":"Cell Host Microbe"},{"key":"B21","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1002\/bmc.580","article-title":"Rapid determination of short-chain fatty acids in colonic contents and faeces of humans and rats by acidified water-extraction and direct-injection gas chromatography","volume":"20","author":"Zhao","year":"2006","journal-title":"Biomed Chromatogr."},{"key":"B22","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1128\/IAI.01432-07","article-title":"Enteric salmonellosis disrupts the microbial ecology of the murine gastrointestinal tract","volume":"76","author":"Barman","year":"2008","journal-title":"Infect Immun."},{"key":"B23","doi-asserted-by":"publisher","first-page":"6561","DOI":"10.1523\/JNEUROSCI.3353-11.2012","article-title":"Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation","volume":"32","author":"Basso","year":"2012","journal-title":"J Neurosci."},{"key":"B24","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/nmeth.f.303","article-title":"QIIME allows analysis of high-throughput community sequencing data","volume":"7","author":"Caporaso","year":"2010","journal-title":"Nat Methods."},{"key":"B25","first-page":"4557","article-title":"A guide to histomorphological evaluation of intestinal inflammation in mouse models","volume":"7","author":"Erben","year":"2014","journal-title":"Int J Clin Exp Pathol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1038\/nprot.2007.41","article-title":"Chemically induced mouse models of intestinal inflammation","volume":"2","author":"Wirtz","year":"2007","journal-title":"Nat Protoc."},{"key":"B27","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1146\/annurev-immunol-030409-101314","article-title":"Adaptive immune regulation in the gut: T cell-dependent and T cell-independent IgA synthesis","volume":"28","author":"Fagarasan","year":"2010","journal-title":"Annu Rev Immunol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1038\/mi.2016.128","article-title":"Gut permeability and mucosal inflammation: bad, good or context dependent","volume":"10","author":"Ahmad","year":"2017","journal-title":"Mucosal Immunol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1084\/jem.20101757","article-title":"Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b","volume":"208","author":"F\u00f6ger","year":"2011","journal-title":"J Exp Med."},{"key":"B30","doi-asserted-by":"publisher","first-page":"3190","DOI":"10.4049\/jimmunol.167.6.3190","article-title":"CD19 can regulate B lymphocyte signal transduction independent of complement activation","volume":"167","author":"Hasegawa","year":"2001","journal-title":"J Immunol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"5379","DOI":"10.4049\/jimmunol.175.8.5379","article-title":"A critical role for complement C3d and the B cell coreceptor (CD19\/CD21) complex in the initiation of inflammatory arthritis","volume":"175","author":"Del Nagro","year":"2005","journal-title":"J Immunol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"163","DOI":"10.4049\/jimmunol.167.1.163","article-title":"The role of the CD19\/CD21 complex in B cell processing and presentation of complement-tagged antigens","volume":"167","author":"Cherukuri","year":"2001","journal-title":"J Immunol."},{"key":"B33","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.4049\/jimmunol.157.10.4371","article-title":"CD19 regulates B lymphocyte signaling thresholds critical for the development of B-1 lineage cells and autoimmunity","volume":"157","author":"Sato","year":"1996","journal-title":"J Immunol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1385\/IR:22:2-3:281","article-title":"CD19 regulates intrinsic B lymphocyte signal transduction and activation through a novel mechanism of processive amplification","volume":"22","author":"Fujimoto","year":"2000","journal-title":"Immunol Res."},{"key":"B35","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.immuni.2005.04.011","article-title":"B-1a and B-1b cells exhibit distinct developmental requirements and have unique functional roles in innate and adaptive immunity to S. pneumonia","volume":"23","author":"Haas","year":"2005","journal-title":"Immunity."},{"key":"B36","doi-asserted-by":"publisher","first-page":"812","DOI":"10.2353\/ajpath.2006.050923","article-title":"Inhibitory role of CD19 in the progression of experimental autoimmune encephalomyelitis by regulating cytokine response","volume":"168","author":"Matsushita","year":"2006","journal-title":"Am J Pathol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"2469","DOI":"10.4049\/jimmunol.167.5.2469","article-title":"A CD19-dependent signaling pathway regulates autoimmunity in Lyn-deficient mice","volume":"167","author":"Hasegawa","year":"2001","journal-title":"J Immunol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1016\/j.ajpath.2010.10.022","article-title":"IL-10-producing regulatory B10 cells inhibit intestinal injury in a mouse model","volume":"178","author":"Yanaba","year":"2011","journal-title":"Am J Pathol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.2353\/ajpath.2008.071049","article-title":"CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma","volume":"172","author":"Yoshizaki","year":"2008","journal-title":"Am J Pathol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.clim.2015.08.010","article-title":"CD21 and CD19 deficiency: Two defects in the same complex leading to different disease modalities","volume":"161","author":"Wentink","year":"2015","journal-title":"Clin Immunol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1056\/NEJMoa051568","article-title":"An antibody-deficiency syndrome due to mutations in the CD19 gene","volume":"354","author":"van Zelm","year":"2006","journal-title":"N Engl J Med."},{"key":"B42","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1586\/eci.09.43","article-title":"Role of B cells in common variable immune deficiency","volume":"5","author":"Ahn","year":"2009","journal-title":"Expert Rev Clin Immunol."},{"key":"B43","doi-asserted-by":"publisher","first-page":"2780","DOI":"10.4049\/jimmunol.1300649","article-title":"Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-gamma+CD4+ T cell numbers during colitis development in mice","volume":"191","author":"Maseda","year":"2013","journal-title":"J Immunol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1002\/ibd.21769","article-title":"B cells exposed to enterobacterial components suppress development of experimental colitis","volume":"18","author":"Schmidt","year":"2012","journal-title":"Inflamm Bowel Dis."},{"key":"B45","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1126\/science.1077336","article-title":"Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora","volume":"298","author":"Fagarasan","year":"2002","journal-title":"Science."},{"key":"B46","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/S0092-8674(00)00078-7","article-title":"Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme","volume":"102","author":"Muramatsu","year":"2000","journal-title":"Cell."},{"key":"B47","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/S1074-7613(00)00044-3","article-title":"TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo","volume":"13","author":"Cazac","year":"2000","journal-title":"Immunity."},{"key":"B48","doi-asserted-by":"publisher","first-page":"3305","DOI":"10.4049\/jimmunol.173.5.3305","article-title":"TGF-beta receptor signaling is critical for mucosal IgA responses","volume":"173","author":"Borsutzky","year":"2004","journal-title":"J Immunol."},{"key":"B49","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.4049\/jimmunol.162.5.2521","article-title":"Targeted deletion of the IgA constant region in mice leads to IgA deficiency with alterations in expression of other Ig isotypes","volume":"162","author":"Harriman","year":"1999","journal-title":"J Immunol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.4049\/jimmunol.175.2.1276","article-title":"Mucosal B cell deficiency in IgA-\/- mice abrogates the development of allergic lung inflammation","volume":"175","author":"Arnaboldi","year":"2005","journal-title":"J Immunol."},{"key":"B51","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1111\/j.1365-2141.2010.08077.x","article-title":"Update on the hyper immunoglobulin M syndromes","volume":"149","author":"Davies","year":"2010","journal-title":"Br J Haematol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1038\/nm.2505","article-title":"Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut","volume":"17","author":"Shulzhenko","year":"2011","journal-title":"Nat Med."},{"key":"B53","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.clim.2018.09.008","article-title":"CVID enteropathy is characterized by exceeding low mucosal IgA levels and interferon-driven inflammation possibly related to the presence of a pathobiont","volume":"197","author":"Shulzhenko","year":"2018","journal-title":"Clin Immunol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1182\/blood-2011-09-377945","article-title":"Morbidity and mortality in common variable immune deficiency over 4 decades","volume":"119","author":"Resnick","year":"2012","journal-title":"Blood."},{"key":"B55","doi-asserted-by":"publisher","first-page":"390","DOI":"10.3390\/pathogens3020390","article-title":"Secretory IgA is concentrated in the outer layer of colonic mucus along with gut bacteria","volume":"3","author":"Rogier","year":"2014","journal-title":"Pathogens."},{"key":"B56","doi-asserted-by":"publisher","first-page":"2033","DOI":"10.1084\/jem.20140039","article-title":"Exhaustion of bacteria-specific CD4 T cells and microbial translocation in common variable immunodeficiency disorders","volume":"211","author":"Perreau","year":"2014","journal-title":"J Exp Med."},{"key":"B57","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/j.jaci.2018.06.012","article-title":"Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responses","volume":"143","author":"Romberg","year":"2019","journal-title":"J Allergy Clin Immunol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1177\/2040622313496126","article-title":"Gastrointestinal bacterial overgrowth: pathogenesis and clinical significance","volume":"4","author":"Sachdev","year":"2013","journal-title":"Ther Adv Chronic Dis."},{"key":"B59","first-page":"112","article-title":"Small intestinal bacterial overgrowth: a comprehensive review","volume":"3","author":"Dukowicz","year":"2007","journal-title":"Gastroenterol Hepatol."},{"key":"B60","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1093\/ageing\/20.1.29","article-title":"Duodenal mucosal morphometry of elderly patients with small intestinal bacterial overgrowth: response to antibiotic treatment","volume":"20","author":"Haboubi","year":"1991","journal-title":"Age Ageing."},{"key":"B61","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1046\/j.1365-2036.2000.00751.x","article-title":"Rifaximin versus chlortetracycline in the short-term treatment of small intestinal bacterial overgrowth","volume":"14","author":"Di Stefano","year":"2000","journal-title":"Aliment Pharmacol Ther."},{"key":"B62","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1111\/j.1365-2036.2005.02397.x","article-title":"Absorbable vs","volume":"21","author":"Di Stefano","year":"2005","journal-title":"Aliment Pharmacol Ther."},{"key":"B63","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1097\/MOG.0000000000000057","article-title":"Bile acids and the gut microbiome","volume":"30","author":"Ridlon","year":"2014","journal-title":"Curr Opin Gastroenterol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1038\/ajg.2009.188","article-title":"Between celiac disease and irritable bowel syndrome: the \u201cNo Man's Land\u201d of Gluten Sensitivity\u201d","volume":"104","author":"Verdu","year":"2009","journal-title":"Am J Gastroenterol."},{"key":"B65","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1053\/j.gastro.2014.12.049","article-title":"Nonceliac gluten and wheat sensitivity","volume":"148","author":"Fasano","year":"2015","journal-title":"Gastroenterology."},{"key":"B66","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1080\/00365520410004901","article-title":"Histology of the terminal ileum in coeliac disease","volume":"39","author":"Dickey","year":"2004","journal-title":"Scand J Gastroenterol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.gtc.2007.01.006","article-title":"Nutritional deficiencies in celiac disease","volume":"36","author":"Barton","year":"2007","journal-title":"Gastroenterol Clin North Am."},{"key":"B68","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1016\/j.dld.2006.04.003","article-title":"The occurrence of terminal ileal histological abnormalities in patients with coeliac disease","volume":"38","author":"Hopper","year":"2006","journal-title":"Dig Liver Dis."},{"key":"B69","doi-asserted-by":"publisher","first-page":"S68","DOI":"10.1053\/j.gastro.2005.02.015","article-title":"Clinical presentation of celiac disease in the pediatric population","volume":"128","author":"Fasano","year":"2005","journal-title":"Gastroenterology."},{"key":"B70","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1136\/gut.2009.195131","article-title":"Classification and management of refractory coeliac disease","volume":"59","author":"Rubio-Tapia","year":"2010","journal-title":"Gut."},{"key":"B71","article-title":"Celiac disease","volume-title":"GeneReviews\u00ae [Internet]","author":"Taylor","year":"2008"},{"key":"B72","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1007\/s10620-015-4020-2","article-title":"Gut microbiota and celiac disease","volume":"61","author":"Marasco","year":"2016","journal-title":"Digest Dis Sci."},{"key":"B73","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1128\/CDLI.9.6.1295-1300.2002","article-title":"Celiac disease and immunoglobulin a deficiency: how effective are the serological methods of diagnosis?","volume":"9","author":"Kumar","year":"2002","journal-title":"Clin Diagn Lab Immunol."},{"key":"B74","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1097\/MCG.0b013e31824b2277","article-title":"Immunoglobulin A deficiency in celiac disease","volume":"46","author":"Chow","year":"2012","journal-title":"J Clin Gastroenterol."},{"key":"B75","first-page":"473","article-title":"Celiac disease and common variable immunodeficiency: a familial inheritance?","volume":"22","author":"Licinio","year":"2013","journal-title":"J Gastrointestin Liver Dis."},{"key":"B76","doi-asserted-by":"publisher","first-page":"2262","DOI":"10.1038\/ajg.2010.214","article-title":"The enteropathy associated with common variable immunodeficiency: the delineated frontiers with celiac disease","volume":"105","author":"Malamut","year":"2010","journal-title":"Am J Gastroenterol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"7486","DOI":"10.3390\/nu7095350","article-title":"Seronegative celiac disease and immunoglobulin deficiency: where to look in the submerged iceberg?","volume":"7","author":"Giorgio","year":"2015","journal-title":"Nutrients."},{"key":"B78","doi-asserted-by":"publisher","first-page":"389","DOI":"10.3389\/fped.2018.00389","article-title":"Microbial transglutaminase is immunogenic and potentially pathogenic in pediatric celiac disease","volume":"6","author":"Torsten","year":"2018","journal-title":"Front Pediatric."}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.02484\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T00:56:22Z","timestamp":1695344182000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2019.02484\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,23]]},"references-count":78,"alternative-id":["10.3389\/fimmu.2019.02484"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2019.02484","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,23]]},"article-number":"2484"}}