{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:38:54Z","timestamp":1790437134128,"version":"4.1.0"},"reference-count":157,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2020.566892","type":"journal-article","created":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:29:56Z","timestamp":1600907396000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":51,"title":["Complement-Mediated Microglial Phagocytosis and Pathological Changes in the Development and Degeneration of the Visual System"],"prefix":"10.3389","volume":"11","author":[{"given":"Davis M.","family":"Borucki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer","family":"Toutonji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Couch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil","family":"Mallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baerbel","family":"Rohrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Tomlinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1146\/annurev-vision-082114-035334","article-title":"Functional circuitry of the retina","volume":"1","author":"Demb","year":"2015","journal-title":"Ann Rev Vis Sci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"99","DOI":"10.4137\/BBI.S6930","article-title":"Mouse retinal development: a dark horse model for systems biology research","volume":"5","author":"Zhang","year":"2011","journal-title":"Bioinformatics Biol Insights."},{"key":"B3","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1017\/S0952523805225154","article-title":"Structural and functional composition of the developing retinogeniculate pathway in the mouse","volume":"22","author":"Jaubert-Miazza","year":"2005","journal-title":"Visual Neurosci."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1016\/j.cell.2007.10.036","article-title":"The classical complement cascade mediates CNS synapse elimination","volume":"131","author":"Stevens","year":"2007","journal-title":"Cell."},{"key":"B5","doi-asserted-by":"publisher","first-page":"2025","DOI":"10.1523\/JNEUROSCI.1854-18.2018","article-title":"Complement targets newborn retinal ganglion cells for phagocytic elimination by microglia","volume":"39","author":"Anderson","year":"2019","journal-title":"J Neurosci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"263","DOI":"10.3389\/fncel.2015.00263","article-title":"Corrigendum: versatility of the complement system in neuroinflammation, neurodegeneration, and brain homeostasis","volume":"9","author":"Orsini","year":"2015","journal-title":"Front Cell Neurosci."},{"key":"B7","doi-asserted-by":"publisher","first-page":"50","DOI":"10.3389\/fneur.2011.00050","article-title":"Optic neuritis and retinal ganglion cell loss in a chronic murine model of multiple sclerosis","volume":"2","author":"Quinn","year":"2011","journal-title":"Front Neurol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1101\/841601","article-title":"Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease","volume":"52","author":"Werneburg","year":"2020","journal-title":"Immunity."},{"key":"B9","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1167\/tvst.7.2.3","article-title":"Encapsulated cell technology-based delivery of a complement inhibitor reduces choroidal neovascularization in a mouse model","volume":"7","author":"Annamalai","year":"2018","journal-title":"Transl Vis Sci Technol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1016\/j.ymthe.2018.08.017","article-title":"Complement C3-targeted gene therapy restricts onset and progression of neurodegeneration in chronic mouse glaucoma","volume":"26","author":"Bosco","year":"2018","journal-title":"Mol Therapy."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.3389\/fphar.2019.01381","article-title":"Intravitreal therapy against the complement factor C5 prevents retinal degeneration in an experimental autoimmune glaucoma model","volume":"10","author":"Reinehr","year":"2019","journal-title":"Front Pharmacol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.ophtha.2019.07.011","article-title":"Complement C3 inhibitor pegcetacoplan for geographic atrophy secondary to age-related macular degeneration: a randomized phase 2 trial","volume":"127","author":"Liao","year":"2020","journal-title":"Ophthalmology."},{"key":"B13","volume-title":"The Complement Factsbook.","author":"Barnum","year":"2018"},{"key":"B14","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1126\/science.1201954","article-title":"A crystal structure of the complex between human complement receptor 2 and its ligand C3d","volume":"332","author":"van den Elsen","year":"2011","journal-title":"Science."},{"key":"B15","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/j.neuron.2012.03.026","article-title":"Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner","volume":"74","author":"Schafer","year":"2012","journal-title":"Neuron."},{"key":"B16","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1006\/exnr.2000.7559","article-title":"Distinct inflammatory stimuli induce different patterns of myelin phagocytosis and degradation in recruited macrophages","volume":"167","author":"Slobodov","year":"2001","journal-title":"Exp Neurol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/S0969-9961(02)00008-6","article-title":"Complement-receptor-3 and scavenger-receptor-AI\/II mediated myelin phagocytosis in microglia and macrophages","volume":"12","author":"Reichert","year":"2003","journal-title":"Neurobiol Dis."},{"key":"B18","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/0006-8993(93)91698-R","article-title":"Synthetic Alzheimer amyloid beta\/A4 peptides enhance production of complement C3 component by cultured microglial cells","volume":"601","author":"Haga","year":"1993","journal-title":"Brain Res."},{"key":"B19","doi-asserted-by":"publisher","first-page":"8240","DOI":"10.1523\/JNEUROSCI.1808-05.2005","article-title":"Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines","volume":"25","author":"Koenigsknecht-Talboo","year":"2005","journal-title":"J Neurosci."},{"key":"B20","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1007\/s00401-003-0798-7","article-title":"Phagocytosis of Escherichia coli by amoeboid microglial cells in the developing brain","volume":"107","author":"Kaur","year":"2004","journal-title":"Acta Neuropathol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"1438","DOI":"10.1016\/j.molimm.2010.02.010","article-title":"Secretion of a fungal protease represents a complement evasion mechanism in cerebral aspergillosis","volume":"47","author":"Rambach","year":"2010","journal-title":"Mol Immunol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1038\/nature18283","article-title":"A complement-microglial axis drives synapse loss during virus-induced memory impairment","volume":"534","author":"Vasek","year":"2016","journal-title":"Nature."},{"key":"B23","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1111\/bpa.12005","article-title":"A shift in microglial \u03b2-amyloid binding in Alzheimer's disease is associated with cerebral amyloid angiopathy","volume":"23","author":"Zabel","year":"2013","journal-title":"Brain Pathol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"6333","DOI":"10.1523\/JNEUROSCI.0829-08.2008","article-title":"Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia\/macrophage phenotype in amyloid precursor protein transgenic mice","volume":"28","author":"Maier","year":"2008","journal-title":"J Neurosci."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1084\/jem.20162011","article-title":"Microglial complement receptor 3 regulates brain A\u03b2 levels through secreted proteolytic activity","volume":"214","author":"Czirr","year":"2017","journal-title":"J Exp Med."},{"key":"B26","doi-asserted-by":"publisher","first-page":"eaaf6295","DOI":"10.1126\/scitranslmed.aaf6295","article-title":"Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP\/PS1 mice","volume":"9","author":"Shi","year":"2017","journal-title":"Sci Transl Med."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1847","DOI":"10.1016\/j.bbadis.2016.07.007","article-title":"Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease","volume":"1862","author":"Kamphuis","year":"2016","journal-title":"Biochim Biophys Acta."},{"key":"B28","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1126\/science.aad8373","article-title":"Complement and microglia mediate early synapse loss in Alzheimer mouse models","volume":"352","author":"Hong","year":"2016","journal-title":"Science."},{"key":"B29","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.4049\/jimmunol.145.9.2984","article-title":"Platelet C1q receptor interactions with collagen- and C1q-coated surfaces","volume":"145","author":"Peerschke","year":"1990","journal-title":"J Immunol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/S1074-7613(00)80356-8","article-title":"Complement receptor type 1 (CR1, CD35) is a receptor for C1q","volume":"7","author":"Klickstein","year":"1997","journal-title":"Immunity."},{"key":"B31","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/S0162-3109(97)00076-3","article-title":"The C1q and collectin binding site within C1 q receptor (cell surface calreticulin)","volume":"38","author":"Stuart","year":"1997","journal-title":"Immunopharmacology."},{"key":"B32","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/S0092-8674(03)00758-X","article-title":"By binding SIRPalpha or calreticulin\/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation","volume":"115","author":"Gardai","year":"2003","journal-title":"Cell."},{"key":"B33","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1182\/blood-2005-06-2218","article-title":"Novel collectin\/C1q receptor mediates mast cell activation and innate immunity","volume":"107","author":"Edelson","year":"2006","journal-title":"Blood."},{"key":"B34","doi-asserted-by":"publisher","first-page":"E3160","DOI":"10.1073\/pnas.1212753109","article-title":"C1q limits dendritic cell differentiation and activation by engaging LAIR-1","volume":"109","author":"Son","year":"2012","journal-title":"Proc Natl Acad Sci."},{"key":"B35","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1038\/ni.2670","article-title":"The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunity","volume":"14","author":"Ramirez-Ortiz","year":"2013","journal-title":"Nat Immunol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1016\/j.molimm.2007.09.008","article-title":"Role of complement and complement regulators in the removal of apoptotic cells","volume":"45","author":"Trouw","year":"2008","journal-title":"Mol Immunol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1111\/j.1471-4159.2009.06494.x","article-title":"C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production","volume":"112","author":"Fraser","year":"2010","journal-title":"J Neurochem."},{"key":"B38","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1016\/j.cell.2016.04.001","article-title":"Progranulin deficiency promotes circuit-specific synaptic pruning by microglia via complement activation","volume":"165","author":"Lui","year":"2016","journal-title":"Cell."},{"key":"B39","doi-asserted-by":"publisher","first-page":"6303","DOI":"10.1073\/pnas.1722613115","article-title":"Local apoptotic-like mechanisms underlie complement-mediated synaptic pruning","volume":"115","author":"Gy\u00f6rffy","year":"2018","journal-title":"Proc Natl Acad Sci USA."},{"key":"B40","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1002\/jnr.21875","article-title":"C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation","volume":"87","author":"F\u00e4rber","year":"2009","journal-title":"J Neurosci Res."},{"key":"B41","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/s13024-017-0210-z","article-title":"Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss","volume":"12","author":"Hernandez","year":"2017","journal-title":"Mol Neurodegener."},{"key":"B42","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1002\/jlb.67.1.109","article-title":"Structural and functional evidence for microglial expression of C1qR(P), the C1q receptor that enhances phagocytosis","volume":"67","author":"Webster","year":"2000","journal-title":"J Leukocyte Biol."},{"key":"B43","article-title":"VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice: Program No. 299.01","volume-title":"2019 Neuroscience Meeting Planner","author":"Salton","year":"2019"},{"key":"B44","article-title":"The efficacy of C5a receptor antagonist for human iPSC-derived neural stem\/progenitor cell transplantation in the injured spinal cord of mice: Program No. 302.05","volume-title":"Neuroscience Meeting Planner","author":"Nakamura","year":"2019"},{"key":"B45","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1523\/JNEUROSCI.2117-15.2016","article-title":"Astrocyte-microglia cross talk through complement activation modulates amyloid pathology in mouse models of Alzheimer's Disease","volume":"36","author":"Lian","year":"2016","journal-title":"J Neurosci."},{"key":"B46","doi-asserted-by":"publisher","first-page":"9042851","DOI":"10.1155\/2017\/9042851","article-title":"Phagocytosis: a fundamental process in immunity","volume":"2017","author":"Rosales","year":"2017","journal-title":"BioMed Res Int."},{"key":"B47","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1006\/exnr.1999.7229","article-title":"Galectin-3\/MAC-2 in experimental allergic encephalomyelitis","volume":"160","author":"Reichert","year":"1999","journal-title":"Exp Neurol."},{"key":"B48","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1002\/glia.20713","article-title":"Galectin-3\/MAC-2, Ras and PI3K activate complement receptor-3 and scavenger receptor-AI\/II mediated myelin phagocytosis in microglia","volume":"56","author":"Rotshenker","year":"2008","journal-title":"Glia."},{"key":"B49","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1002\/glia.20304","article-title":"Non-PKC DAG\/phorbol-ester receptor(s) inhibit complement receptor-3 and nPKC inhibit scavenger receptor-AI\/II-mediated myelin phagocytosis but cPKC, PI3k, and PLCgamma activate myelin phagocytosis by both","volume":"53","author":"Cohen","year":"2006","journal-title":"Glia."},{"key":"B50","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1002\/glia.20303","article-title":"cAMP cascade (PKA, Epac, adenylyl cyclase, Gi, and phosphodiesterases) regulates myelin phagocytosis mediated by complement receptor-3 and scavenger receptor-AI\/II in microglia and macrophages","volume":"53","author":"Makranz","year":"2006","journal-title":"Glia."},{"key":"B51","doi-asserted-by":"publisher","first-page":"2211","DOI":"10.1096\/fj.09-146118","article-title":"Cytoskeleton plays a dual role of activation and inhibition in myelin and zymosan phagocytosis by microglia","volume":"24","author":"Gitik","year":"2010","journal-title":"FASEB J."},{"key":"B52","doi-asserted-by":"publisher","first-page":"587463","DOI":"10.4061\/2010\/587463","article-title":"Microglial immunoreceptor tyrosine-based activation and inhibition motif signaling in neuroinflammation","volume":"2010","author":"Linnartz","year":"2010","journal-title":"Int J Alzheimer's Dis."},{"key":"B53","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1002\/glia.23563","article-title":"TREM2 triggers microglial density and age-related neuronal loss","volume":"67","author":"Linnartz-Gerlach","year":"2019","journal-title":"Glia."},{"key":"B54","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1186\/s12964-019-0461-0","article-title":"TAM receptors, Phosphatidylserine, inflammation, and Cancer","volume":"17","author":"Burstyn-Cohen","year":"2019","journal-title":"Cell Commun Signal."},{"key":"B55","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1038\/s41577-018-0051-1","article-title":"Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight","volume":"18","author":"Shi","year":"2018","journal-title":"Nat Rev Immunol."},{"key":"B56","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1038\/nature12776","article-title":"Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways","volume":"504","author":"Chung","year":"2013","journal-title":"Nature."},{"key":"B57","doi-asserted-by":"publisher","first-page":"5185","DOI":"10.1523\/JNEUROSCI.3850-15.2016","article-title":"Megf10 Is a receptor for C1Q that mediates clearance of apoptotic cells by astrocytes","volume":"36","author":"Iram","year":"2016","journal-title":"J Neurosci."},{"key":"B58","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/BF01217304","article-title":"Evidence that the lamina cribrosa prevents intraretinal myelination of retinal ganglion cell axons","volume":"19","author":"Perry","year":"1990","journal-title":"J Neurocytol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"E008","DOI":"10.1017\/S0952523817000062","article-title":"Organization of the dorsal lateral geniculate nucleus in the mouse","volume":"34","author":"Kerschensteiner","year":"2017","journal-title":"Vis Neurosci."},{"key":"B60","doi-asserted-by":"publisher","first-page":"1759091414562107","DOI":"10.1177\/1759091414562107","article-title":"Connecting the retina to the brain","volume":"6","author":"Erskine","year":"2014","journal-title":"ASN Neuro."},{"key":"B61","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1146\/annurev-vision-082114-035502","article-title":"Contributions of retinal ganglion cells to subcortical visual processing and behaviors","volume":"1","author":"Dhande","year":"2015","journal-title":"Ann Rev Vis Sci."},{"key":"B62","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.conb.2011.02.007","article-title":"Wiring and rewiring of the retinogeniculate synapse","volume":"21","author":"Hong","year":"2011","journal-title":"Curr Opin Neurobiol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"142","DOI":"10.3758\/BF03326707","article-title":"The primary visual system of the rat: A primer of its anatomy","volume":"6","author":"LeVere","year":"1978","journal-title":"Physiol Psychol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"e12418","DOI":"10.1371\/journal.pone.0012418","article-title":"Mouse gestation length is genetically determined","volume":"5","author":"Murray","year":"2010","journal-title":"PLoS ONE."},{"key":"B65","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1002\/cne.902300406","article-title":"Prenatal and postnatal development of retinogeniculate and retinocollicular projections in the mouse","volume":"230","author":"Godement","year":"1984","journal-title":"J Comp Neurol."},{"key":"B66","doi-asserted-by":"publisher","first-page":"1773","DOI":"10.1038\/nn.3560","article-title":"TGF-\u03b2 signaling regulates neuronal C1q expression and developmental synaptic refinement","volume":"16","author":"Bialas","year":"2013","journal-title":"Nat Neurosci."},{"key":"B67","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1126\/science.aaz2288","article-title":"Microglia mediate forgetting via complement-dependent synaptic elimination","volume":"367","author":"Wang","year":"2020","journal-title":"Science."},{"key":"B68","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.1038\/s41467-019-08976-7","article-title":"Transcriptional profiling of human microglia reveals grey\u2013white matter heterogeneity and multiple sclerosis-associated changes","volume":"10","author":"van der Poel","year":"2019","journal-title":"Nat Commun."},{"key":"B69","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1016\/j.molimm.2006.03.007","article-title":"Role of complement in neurodegeneration and neuroinflammation","volume":"44","author":"Bonifati","year":"2007","journal-title":"Mol Immunol."},{"key":"B70","doi-asserted-by":"publisher","first-page":"3163","DOI":"10.3892\/etm.2017.4410","article-title":"Multiple sclerosis: pathology, diagnosis and treatments","volume":"13","author":"Huang","year":"2017","journal-title":"Exp Ther Med."},{"key":"B71","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1111\/cei.12271","article-title":"Neuromyelitis optica: clinical features, immunopathogenesis and treatment","volume":"176","author":"Jarius","year":"2014","journal-title":"Clin Exp Immunol."},{"key":"B72","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1007\/s00415-018-9122-2","article-title":"Neurological update: MOG antibody disease","volume":"266","author":"Wynford-Thomas","year":"2019","journal-title":"J Neurol."},{"key":"B73","first-page":"33","article-title":"Acute stroke diagnosis","volume":"80","author":"Yew","year":"2009","journal-title":"Am Fam Phys."},{"key":"B74","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s13311-011-0053-1","article-title":"Stroke epidemiology: advancing our understanding of disease mechanism and therapy","volume":"8","author":"Ovbiagele","year":"2011","journal-title":"Neurotherapeutics."},{"key":"B75","article-title":"Traumatic brain injury","volume-title":"StatPearls","author":"Georges","year":"2020"},{"key":"B76","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/B978-0-444-52892-6.00004-0","article-title":"The neuropathology of traumatic brain injury","volume":"127","author":"McKee","year":"2015","journal-title":"Handbook Clin Neurol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"a017236","DOI":"10.1101\/cshperspect.a017236","article-title":"Clinical characteristics and current treatment of glaucoma","volume":"4","author":"Cohen","year":"2014","journal-title":"Cold Spring Harbor Perspect Med."},{"key":"B78","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1001\/jama.2014.3192","article-title":"The pathophysiology and treatment of glaucoma: a review","volume":"311","author":"Weinreb","year":"2014","journal-title":"JAMA."},{"key":"B79","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1186\/s12889-019-6935-6","article-title":"Prevalence, incidence, and risk factors of primary open-angle glaucoma - a cohort study based on longitudinal data from a German public health insurance","volume":"19","author":"Kreft","year":"2019","journal-title":"BMC Public Health."},{"key":"B80","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1080\/07853890600946724","article-title":"Age-related macular degeneration\u2013emerging pathogenetic and therapeutic concepts","volume":"38","author":"Gehrs","year":"2006","journal-title":"Ann Med."},{"key":"B81","doi-asserted-by":"publisher","first-page":"e8926","DOI":"10.15252\/emmm.201808926","article-title":"Early auto-immune targeting of photoreceptor ribbon synapses in mouse models of multiple sclerosis","volume":"10","author":"Dembla","year":"2018","journal-title":"EMBO Mol Med."},{"key":"B82","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1002\/ana.24398","article-title":"Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus","volume":"77","author":"Michailidou","year":"2015","journal-title":"Ann Neurol."},{"key":"B83","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1084\/jem.20050304","article-title":"IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel","volume":"202","author":"Lennon","year":"2005","journal-title":"J Exp Med."},{"key":"B84","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/S0165-5728(99)00133-2","article-title":"The role of anti-myelin (auto)-antibodies in the phagocytosis of myelin by macrophages","volume":"101","author":"Van der Goes","year":"1999","journal-title":"J Neuroimmunol."},{"key":"B85","doi-asserted-by":"publisher","first-page":"aao6459","DOI":"10.1126\/scitranslmed.aao6459","article-title":"Targeted complement inhibition salvages stressed neurons and inhibits neuroinflammation after stroke in mice","volume":"10","author":"Alawieh","year":"2018","journal-title":"Sci Transl Med."},{"key":"B86","doi-asserted-by":"publisher","first-page":"4042","DOI":"10.1523\/JNEUROSCI.2462-19.2020","article-title":"Complement-dependent synaptic uptake and cognitive decline after stroke and reperfusion therapy","volume":"40","author":"Alawieh","year":"2020","journal-title":"J Neurosci."},{"key":"B87","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1089\/08977150152725605","article-title":"Complement activation in the human brain after traumatic head injury","volume":"18","author":"Bellander","year":"2001","journal-title":"J Neurotrauma."},{"key":"B88","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1080\/14737159.2018.1471985","article-title":"Complement cascade on severe traumatic brain injury patients at the chronic unconscious stage: implication for pathogenesis","volume":"18","author":"Bao","year":"2018","journal-title":"Exp Rev Mol Diagn."},{"key":"B89","doi-asserted-by":"publisher","first-page":"2519","DOI":"10.1523\/JNEUROSCI.2197-17.2018","article-title":"Identifying the role of complement in triggering neuroinflammation after traumatic brain injury","volume":"38","author":"Alawieh","year":"2018","journal-title":"J Neurosci."},{"key":"B90","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1172\/JCI44646","article-title":"Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma","volume":"121","author":"Howell","year":"2011","journal-title":"J Clin Investig."},{"key":"B91","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1007\/s00347-014-3100-6","article-title":"Complement activation after induction of ocular hypertension in an animal model","volume":"112","author":"Becker","year":"2014","journal-title":"Ophthalmologe."},{"key":"B92","doi-asserted-by":"publisher","first-page":"6370","DOI":"10.1167\/iovs.12-10442","article-title":"Lack of immunoglobulins does not prevent C1q binding to RGC and does not alter the progression of experimental glaucoma","volume":"53","author":"Ding","year":"2012","journal-title":"Investig Ophthalmol Vis Sci."},{"key":"B93","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13024-016-0091-6","article-title":"Inhibition of the classical pathway of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma","volume":"11","author":"Williams","year":"2016","journal-title":"Mol Neurodegener."},{"key":"B94","doi-asserted-by":"publisher","first-page":"2151","DOI":"10.1016\/j.molimm.2011.07.012","article-title":"Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma","volume":"48","author":"Jha","year":"2011","journal-title":"Mol Immunol."},{"key":"B95","doi-asserted-by":"publisher","first-page":"7227","DOI":"10.1073\/pnas.0501536102","article-title":"A common haplotype in the complement regulatory gene factor H (HF1\/CFH) predisposes individuals to age-related macular degeneration","volume":"102","author":"Hageman","year":"2005","journal-title":"Proc Natl Acad Sci USA."},{"key":"B96","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1038\/ng1750","article-title":"Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration","volume":"38","author":"Gold","year":"2006","journal-title":"Nat Genet."},{"key":"B97","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1056\/NEJMoa072618","article-title":"Complement C3 variant and the risk of age-related macular degeneration","volume":"357","author":"Yates","year":"2007","journal-title":"New Engl J Med."},{"key":"B98","doi-asserted-by":"publisher","first-page":"491","DOI":"10.4049\/jimmunol.174.1.491","article-title":"Role of complement and complement membrane attack complex in laser-induced choroidal neovascularization","volume":"174","author":"Bora","year":"2005","journal-title":"J Immunol."},{"key":"B99","doi-asserted-by":"publisher","first-page":"1872","DOI":"10.4049\/jimmunol.177.3.1872","article-title":"Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H","volume":"177","author":"Bora","year":"2006","journal-title":"J Immunol."},{"key":"B100","doi-asserted-by":"publisher","first-page":"5282","DOI":"10.1167\/iovs.07-0282","article-title":"Eliminating complement factor d reduces photoreceptor susceptibility to light-induced damage","volume":"48","author":"Rohrer","year":"2007","journal-title":"Investig Ophthalmol Vis Sci."},{"key":"B101","doi-asserted-by":"publisher","first-page":"e67894","DOI":"10.1371\/journal.pone.0067894","article-title":"Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury","volume":"8","author":"Woodell","year":"2013","journal-title":"PLoS ONE."},{"key":"B102","doi-asserted-by":"publisher","first-page":"7348","DOI":"10.1038\/s41598-018-30162-w","article-title":"Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy","volume":"8","author":"Katschke","year":"2018","journal-title":"Sci Rep."},{"key":"B103","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1038\/eye.2001.142","article-title":"Structure and composition of drusen associated with glomerulonephritis: implications for the role of complement activation in drusen biogenesis","volume":"15","author":"Mullins","year":"2001","journal-title":"Eye."},{"key":"B104","doi-asserted-by":"publisher","first-page":"2328","DOI":"10.1073\/pnas.0408835103","article-title":"Drusen complement components C3a and C5a promote choroidal neovascularization","volume":"103","author":"Nozaki","year":"2006","journal-title":"Proc Natl Acad Sci USA."},{"key":"B105","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/s12967-018-1434-6","article-title":"RPE phagocytic function declines in age-related macular degeneration and is rescued by human umbilical tissue derived cells","volume":"16","author":"Inana","year":"2018","journal-title":"J Transl Med."},{"key":"B106","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/978-1-4614-3209-8_34","article-title":"Should I Stay or Should I Go? Trafficking of Sub-Lytic MAC in the retinal pigment epithelium","volume-title":"Retinal Degenerative Diseases","author":"Lakkaraju","year":"2014"},{"key":"B107","doi-asserted-by":"publisher","first-page":"8108","DOI":"10.1167\/iovs.10-6418","article-title":"Complement deposition and microglial activation in the outer retina in light-induced retinopathy: inhibition by a 5-HT1A agonist","volume":"52","author":"Collier","year":"2011","journal-title":"Investig Ophthalmol Vis Sci."},{"key":"B108","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1016\/j.molimm.2011.04.003","article-title":"Complement in the brain","volume":"48","author":"Veerhuis","year":"2011","journal-title":"Mol Immunol."},{"key":"B109","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1111\/j.1365-2567.2009.03225.x","article-title":"Inflammation in neurodegenerative diseases","volume":"129","author":"Amor","year":"2010","journal-title":"Immunology."},{"key":"B110","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1002\/jemt.1123","article-title":"Phagocytic properties of microglia in vitro: implications for a role in multiple sclerosis and EAE","volume":"54","author":"Smith","year":"2001","journal-title":"Microsc Res Techn."},{"key":"B111","doi-asserted-by":"publisher","first-page":"2722","DOI":"10.1093\/brain\/awz188","article-title":"Early complement genes are associated with visual system degeneration in multiple sclerosis","volume":"142","author":"Fitzgerald","year":"2019","journal-title":"Brain."},{"key":"B112","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1186\/s40478-019-0767-6","article-title":"Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis","volume":"7","author":"Jin","year":"2019","journal-title":"Acta Neuropathol Commun."},{"key":"B113","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.neulet.2012.10.012","article-title":"Targeted inhibition of complement using complement receptor 2-conjugated inhibitors attenuates EAE","volume":"531","author":"Hu","year":"2012","journal-title":"Neurosci Lett."},{"key":"B114","doi-asserted-by":"publisher","first-page":"374","DOI":"10.3389\/fimmu.2020.00374","article-title":"Microglia in multiple sclerosis: friend or foe?","volume":"11","author":"Guerrero","year":"2020","journal-title":"Front Immunol."},{"key":"B115","doi-asserted-by":"publisher","first-page":"1900","DOI":"10.1093\/brain\/awx113","article-title":"Loss of \u2018homeostatic' microglia and patterns of their activation in active multiple sclerosis","volume":"140","author":"Zrzavy","year":"2017","journal-title":"Brain."},{"key":"B116","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1002\/glia.23726","article-title":"Pathology of inflammatory diseases of the nervous system: human disease versus animal models","volume":"68","author":"Lassmann","year":"2020","journal-title":"Glia."},{"key":"B117","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1093\/brain\/awh707","article-title":"Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis","volume":"129","author":"Boven","year":"2005","journal-title":"Brain."},{"key":"B118","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1038\/nn.3469","article-title":"M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination","volume":"16","author":"Miron","year":"2013","journal-title":"Nat Neurosci."},{"key":"B119","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1097\/00055735-200212000-00006","article-title":"Acute demyelinating optic neuritis","volume":"13","author":"Foroozan","year":"2002","journal-title":"Curr Opin Ophthalmol."},{"key":"B120","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/cen3.12354","article-title":"Clinical characteristics of autoimmune optic neuritis","volume":"8","author":"Kawachi","year":"2017","journal-title":"Clin Exp Neuroimmunol."},{"key":"B121","doi-asserted-by":"publisher","first-page":"10010","DOI":"10.1038\/s41598-019-46232-6","article-title":"The astrocyte transcriptome in EAE optic neuritis shows complement activation and reveals a sex difference in astrocytic C3 expression","volume":"9","author":"Tassoni","year":"2019","journal-title":"Sci Rep."},{"key":"B122","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1097\/WNO.0000000000000508","article-title":"Neuromyelitis optica: deciphering a complex immune-mediated astrocytopathy","volume":"37","author":"Bennett","year":"2017","journal-title":"J Neuro Ophthalmol."},{"key":"B123","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/1742-2094-11-64","article-title":"Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia","volume":"11","author":"Hendrickx","year":"2014","journal-title":"J Neuroinflamm."},{"key":"B124","doi-asserted-by":"crossref","first-page":"4892","DOI":"10.4049\/jimmunol.156.12.4892","article-title":"Sublytic complement attack induces cell cycle in oligodendrocytes","volume":"156","author":"Rus","year":"1996","journal-title":"J Immunol."},{"key":"B125","doi-asserted-by":"publisher","first-page":"3319","DOI":"10.1523\/JNEUROSCI.13-08-03319.1993","article-title":"Specific induction of intracellular calcium oscillations by complement membrane attack on oligodendroglia","volume":"13","author":"Wood","year":"1993","journal-title":"J Neurosci."},{"key":"B126","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1002\/glia.22535","article-title":"Myelin inhibits oligodendroglial maturation and regulates oligodendrocytic transcription factor expression","volume":"61","author":"Plemel","year":"2013","journal-title":"Glia."},{"key":"B127","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1038\/373","article-title":"Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions","volume":"1","author":"Thallmair","year":"1998","journal-title":"Nat Neurosci."},{"key":"B128","doi-asserted-by":"publisher","first-page":"1","DOI":"10.9734\/OR\/2016\/21767","article-title":"Post-stroke visual impairment: a systematic literature review of types and recovery of visual conditions","volume":"5","author":"Hepworth","year":"2016","journal-title":"Ophthalmol Res."},{"key":"B129","doi-asserted-by":"publisher","first-page":"351","DOI":"10.11476\/shinkeiganka.33.351","article-title":"Visual field defects and retinal changes due to cortical disorders","volume":"33","author":"Yamashita","year":"2016","journal-title":"Neuro Ophthalmol Japan."},{"key":"B130","doi-asserted-by":"publisher","first-page":"156","DOI":"10.3389\/fneur.2013.00156","article-title":"Can chronic remote cortical hypoperfusion induced by thalamic infarction cause damage of tracts passing through those hypoperfused regions?","volume":"4","author":"Magnin","year":"2013","journal-title":"Front Neurol."},{"key":"B131","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1053\/jscd.2000.18741","article-title":"Pure thalamic infarctions: clinical findings","volume":"9","author":"Kumral","year":"2000","journal-title":"J Stroke Cerebrovasc Dis."},{"key":"B132","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1111\/cxo.12670","article-title":"Visual problems associated with traumatic brain injury","volume":"101","author":"Armstrong","year":"2018","journal-title":"Clin Exp Optom."},{"key":"B133","doi-asserted-by":"publisher","first-page":"2470","DOI":"10.1093\/brain\/awh294","article-title":"Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injury","volume":"127","author":"Maxwell","year":"2004","journal-title":"Brain."},{"key":"B134","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/brb3.454","article-title":"Deficits in visual system functional connectivity after blast-related Mild TBI are associated with injury severity and executive dysfunction","volume":"6","author":"Gilmore","year":"2016","journal-title":"Brain Behav."},{"key":"B135","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1097\/OPX.0000000000000899","article-title":"Retrograde degeneration of retinal ganglion cells secondary to head trauma","volume":"94","author":"Vien","year":"2017","journal-title":"Optometr Vis Sci."},{"key":"B136","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/S0300-483X(97)03654-8","article-title":"Visual system degeneration induced by blast overpressure","volume":"121","author":"Petras","year":"1997","journal-title":"Toxicology."},{"key":"B137","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1179\/016164101101198334","article-title":"Impaired motor learning and diffuse axonal damage in motor and visual systems of the rat following traumatic brain injury","volume":"23","author":"Ding","year":"2001","journal-title":"Neurol Res."},{"key":"B138","doi-asserted-by":"publisher","first-page":"e0197346","DOI":"10.1371\/journal.pone.0197346","article-title":"Optic tract injury after closed head traumatic brain injury in mice: a model of indirect traumatic optic neuropathy","volume":"13","author":"Evanson","year":"2018","journal-title":"PLoS ONE."},{"key":"B139","doi-asserted-by":"publisher","first-page":"3151","DOI":"10.3390\/ijms19103151","article-title":"Chronic upregulation of cleaved-caspase-3 associated with chronic myelin pathology and microvascular reorganization in the thalamus after traumatic brain injury in rats","volume":"19","author":"Glushakov","year":"2018","journal-title":"Int J Mol Sci."},{"key":"B140","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/j.expneurol.2016.12.012","article-title":"Adaptive reorganization of retinogeniculate axon terminals in dorsal lateral geniculate nucleus following experimental mild traumatic brain injury","volume":"289","author":"Patel","year":"2017","journal-title":"Exp Neurol."},{"key":"B141","doi-asserted-by":"publisher","first-page":"18697","DOI":"10.1073\/pnas.0607283103","article-title":"Autoantibody-mediated demyelination depends on complement activation but not activatory Fc-receptors","volume":"103","author":"Urich","year":"2006","journal-title":"Proc Natl Acad Sci USA."},{"key":"B142","doi-asserted-by":"publisher","first-page":"4962","DOI":"10.4049\/jimmunol.1401613","article-title":"Identification of factor h-like protein 1 as the predominant complement regulator in Bruch's Membrane: Implications for age-related macular degeneration","volume":"193","author":"Clark","year":"2014","journal-title":"J Immunol."},{"key":"B143","doi-asserted-by":"publisher","first-page":"6525","DOI":"10.1167\/iovs.14-15067","article-title":"Reliability of the mouse model of choroidal neovascularization induced by laser photocoagulation","volume":"55","author":"Poor","year":"2014","journal-title":"Investig Ophthalmol Vis Sci."},{"key":"B144","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1167\/iovs.15-18471","article-title":"A targeted inhibitor of the alternative complement pathway accelerates recovery from smoke-induced ocular injury","volume":"57","author":"Woodell","year":"2016","journal-title":"Investig Ophthalmol Vis Sci."},{"key":"B145","doi-asserted-by":"publisher","first-page":"2782","DOI":"10.1167\/iovs.06-1283","article-title":"Dendritic and synaptic plasticity of neurons in the human age-related macular degeneration retina","volume":"48","author":"Sullivan","year":"2007","journal-title":"Investig Ophthalmol Vis Sci."},{"key":"B146","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/j.ophtha.2013.09.044","article-title":"Systemic complement inhibition with eculizumab for geographic atrophy in age-related macular degeneration: The COMPLETE study","volume":"121","author":"Yehoshua","year":"2014","journal-title":"Ophthalmology."},{"key":"B147","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1001\/jamaophthalmol.2018.1544","article-title":"Efficacy and Safety of lampalizumab for geographic atrophy due to age-related macular degeneration: chroma and spectri phase 3 randomized clinical trials","volume":"136","author":"Holz","year":"2018","journal-title":"JAMA Ophthalmol."},{"key":"B148","doi-asserted-by":"publisher","first-page":"154","DOI":"10.3389\/fimmu.2020.00154","article-title":"A systematic investigation on complement pathway activation in diabetic retinopathy","volume":"11","author":"Shahulhameed","year":"2020","journal-title":"Front Immunol."},{"key":"B149","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3980\/j.issn.2222-3959.2015.01.03","article-title":"Activated complement classical pathway in a murine model of oxygen-induced retinopathy","volume":"8","author":"Tao","year":"2015","journal-title":"Int J Ophthalmol."},{"key":"B150","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.3389\/fimmu.2017.01868","article-title":"Abnormal complement activation and inflammation in the pathogenesis of retinopathy of prematurity","volume":"8","author":"Rathi","year":"2017","journal-title":"Front Immunol."},{"key":"B151","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1056\/NEJMoa1900866","article-title":"Eculizumab in aquaporin-4-positive neuromyelitis optica spectrum disorder","volume":"381","author":"Pittock","year":"2019","journal-title":"New Engl J Med."},{"key":"B152","doi-asserted-by":"publisher","first-page":"1693","DOI":"10.3390\/ijms20071693","article-title":"Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules","volume":"20","author":"Nebbioso","year":"2019","journal-title":"Int J Mol Sci."},{"key":"B153","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.omtm.2017.11.003","article-title":"Delivery of CR2-fH using AAV vector therapy as treatment strategy in the mouse model of choroidal neovascularization","volume":"9","author":"Schnabolk","year":"2018","journal-title":"Mol Ther Methods Clin Dev."},{"key":"B154","doi-asserted-by":"publisher","first-page":"2804","DOI":"10.1182\/blood-2014-02-522128","article-title":"Paroxysmal nocturnal hemoglobinuria","volume":"124","author":"Brodsky","year":"2014","journal-title":"Blood."},{"key":"B155","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1111\/1744-9987.12763","article-title":"Atypical hemolytic-uremic syndrome: an update on pathophysiology, diagnosis, and treatment","volume":"23","author":"Raina","year":"2019","journal-title":"Ther Apheresis Dialysis."},{"key":"B156","doi-asserted-by":"publisher","first-page":"eaaf1443","DOI":"10.1126\/scitranslmed.aaf1443","article-title":"Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration","volume":"9","author":"Yaspan","year":"2017","journal-title":"Sci Transl Med."},{"key":"B157","doi-asserted-by":"publisher","first-page":"2444","DOI":"10.1172\/JCI25208","article-title":"Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection","volume":"115","author":"Atkinson","year":"2005","journal-title":"J Clin Invest."}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2020.566892\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T23:10:06Z","timestamp":1696720206000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2020.566892\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,24]]},"references-count":157,"alternative-id":["10.3389\/fimmu.2020.566892"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2020.566892","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,24]]},"article-number":"566892"}}