{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:55:54Z","timestamp":1753890954511,"version":"3.41.2"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2020.572289","type":"journal-article","created":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T05:12:38Z","timestamp":1602738758000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Duck HMGB2 Mediates Signaling Pathways in the Innate Immunity of Hosts Against Viral Infections"],"prefix":"10.3389","volume":"11","author":[{"given":"Tingting","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenhong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolan","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liangmeng","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,10,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.bbagrm.2009.11.009","article-title":"HMG modifications and nuclear function","volume":"1799","author":"Zhang","year":"2010","journal-title":"Biochim Biophys Acta."},{"key":"B2","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1111\/j.1365-2796.2003.01296.x","article-title":"Regulated expression and subcellular localization of HMGB1, a chromatin protein with a cytokine function","volume":"255","author":"Muller","year":"2004","journal-title":"J Intern Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1042\/bst0290395","article-title":"HMG 1 and 2: architectural DNA-binding proteins","volume":"29","author":"Thomas","year":"2001","journal-title":"Biochem Soc Trans."},{"key":"B4","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/1297-9716-45-66","article-title":"Duck MDA5 functions in innate immunity against H5N1 highly pathogenic avian influenza virus infections","volume":"45","author":"Wei","year":"2014","journal-title":"Vet Res."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.3382\/ps\/pev082","article-title":"Molecular cloning and immune responsive expression of LGP2 gene, a pivotal member of the RLR gene family from Muscovy duck Cairina moschata","volume":"94","author":"Jiao","year":"2015","journal-title":"Poult Sci."},{"key":"B6","doi-asserted-by":"publisher","first-page":"2290","DOI":"10.3382\/ps\/pew162","article-title":"Cloning, characterization, and expression analysis of LGP2 cDNA from goose, Anser cygnoides","volume":"95","author":"Wei","year":"2016","journal-title":"Poult Sci."},{"key":"B7","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1111\/j.1365-2796.2011.02433.x","article-title":"Essential role of high-mobility group box proteins in nucleic acid-mediated innate immune responses","volume":"270","author":"Yanai","year":"2011","journal-title":"J Intern Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1016\/j.it.2012.10.005","article-title":"High-mobility group box family of proteins: ligand and sensor for innate immunity","volume":"33","author":"Yanai","year":"2012","journal-title":"Trends Immunol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"109953","DOI":"10.1016\/j.vetimm.2019.109953","article-title":"Evaluation of immunogenicity and protective efficacy of a CpG-adjuvanted DNA vaccine against Tembusu virus","volume":"218","author":"Chen","year":"2019","journal-title":"Vet Immunol Immunopathol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"2892","DOI":"10.3382\/ps.2013-03356","article-title":"The comprehensive diagnosis and prevention of duck plague in northwest Shandong province of China","volume":"92","author":"Wang","year":"2013","journal-title":"Poult Sci."},{"key":"B11","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.vetmic.2016.07.015","article-title":"The pathogenicity of novel duck reovirus in Cherry Valley ducks","volume":"192","author":"Li","year":"2016","journal-title":"Vet Microbiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1186\/s13567-020-00742-8","article-title":"High-mobility group box 1 protein (HMGB1) from Cherry Valley duck mediates signaling pathways and antiviral activity","volume":"51","author":"Hou","year":"2020","journal-title":"Vet Res."},{"key":"B13","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.dci.2013.06.002","article-title":"Characterizations of two grass carp Ctenopharyngodon idella HMGB2 genes and potential roles in innate immunity","volume":"41","author":"Rao","year":"2013","journal-title":"Dev Comp Immunol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1016\/j.fsi.2018.10.066","article-title":"High mobility group box 2 of black rockfish Sebastes schlegelii: Gene cloning, immunoregulatory properties and antibacterial effect","volume":"84","author":"Wang","year":"2019","journal-title":"Fish Shellfish Immunol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"425","DOI":"10.3389\/fmicb.2015.00425","article-title":"Immune responses of ducks infected with duck Tembusu virus","volume":"6","author":"Li","year":"2015","journal-title":"Front Microbiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"32183","DOI":"10.1038\/srep32183","article-title":"Pathogenicity of duck plague and innate immune responses of the Cherry Valley ducks to duck plague virus","volume":"6","author":"Li","year":"2016","journal-title":"Sci Rep."},{"key":"B17","doi-asserted-by":"publisher","first-page":"5237","DOI":"10.1128\/MCB.19.8.5237","article-title":"Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins","volume":"19","author":"Bustin","year":"1999","journal-title":"Mol Cell Biol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.gde.2005.08.007","article-title":"HMG proteins: dynamic players in gene regulation and differentiation","volume":"15","author":"Bianchi","year":"2005","journal-title":"Curr Opin Genet Dev."},{"key":"B19","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.bbagrm.2009.11.005","article-title":"HMGB proteins and transcriptional regulation","volume":"1799","author":"Ueda","year":"2010","journal-title":"Biochim Biophys Acta."},{"key":"B20","unstructured":"Reduced fertility and spermatogenesis defects in mice lacking chromosomal protein Hmgb2126573\n            RonfaniL\n            FerragutiM\n            CrociL\n            OvittC\n            ScholerH\n            ConsalezG\n          11262228Development.1282001"},{"key":"B21","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1097\/SHK.0b013e3181a551bd","article-title":"Novel HMGB1-inhibiting therapeutic agents for experimental sepsis","volume":"32","author":"Wang","year":"2009","journal-title":"Shock."},{"key":"B22","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1038\/nature08512","article-title":"HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses","volume":"462","author":"Yanai","year":"2009","journal-title":"Nature."},{"key":"B23","doi-asserted-by":"publisher","first-page":"4185","DOI":"10.2174\/138161210794519093","article-title":"Antiviral Sensing in Teleost Fish","volume":"16","author":"Zou","year":"2010","journal-title":"Curr Pharm Des."},{"key":"B24","doi-asserted-by":"publisher","first-page":"5551","DOI":"10.1093\/emboj\/cdg516","article-title":"Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion","volume":"22","author":"Bonaldi","year":"2003","journal-title":"EMBO J."},{"key":"B25","unstructured":"Augmenter of liver regeneration (Alr) regulates acute pancreatitis via inhibiting HMGB1\/TLR4\/NF-\u03baB signaling pathway40210\n            PanL-F\n            YuL\n            WangL-M\n            HeJ\n            SunJ\n            WangX\n          Am J Transl Res.102018"},{"key":"B26","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.virol.2018.09.001","article-title":"Newcastle disease virus infection triggers HMGB1 release to promote the inflammatory response","volume":"525","author":"Qu","year":"2018","journal-title":"Virology."},{"key":"B27","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.fsi.2014.01.013","article-title":"Antibacterial and antiviral properties of tongue sole (Cynoglossus semilaevis) high mobility group B2 protein are largely independent on the acidic C-terminal domain","volume":"37","author":"Long","year":"2014","journal-title":"Fish Shellfish Immunol."}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2020.572289\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T05:12:45Z","timestamp":1602738765000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2020.572289\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,15]]},"references-count":27,"alternative-id":["10.3389\/fimmu.2020.572289"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2020.572289","relation":{},"ISSN":["1664-3224"],"issn-type":[{"type":"electronic","value":"1664-3224"}],"subject":[],"published":{"date-parts":[[2020,10,15]]},"article-number":"572289"}}