{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T15:33:05Z","timestamp":1776353585586,"version":"3.51.2"},"reference-count":82,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T00:00:00Z","timestamp":1600300800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2020.572865","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T05:09:35Z","timestamp":1600319375000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":53,"title":["Immunomodulation and Immune Escape Strategies of Gastrointestinal Helminths and Schistosomes"],"prefix":"10.3389","volume":"11","author":[{"given":"Marie","family":"Wiedemann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Voehringer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1016\/j.immuni.2018.10.016","article-title":"Modulation of host immunity by helminths: the expanding repertoire of parasite effector molecules","volume":"49","author":"Maizels","year":"2018","journal-title":"Immunity."},{"key":"B2","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1038\/s41588-018-0262-1","article-title":"Comparative genomics of the major parasitic worms","volume":"51","year":"2019","journal-title":"Nat Genet"},{"key":"B3","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1038\/s41572-018-0013-8","article-title":"Schistosomiasis","volume":"4","author":"McManus","year":"2018","journal-title":"Nat Rev Dis Primers."},{"key":"B4","doi-asserted-by":"publisher","first-page":"135","DOI":"10.3347\/kjp.2015.53.1.135","article-title":"Intestinal nematodes from small mammals captured near the demilitarized zone, Gyeonggi province, republic of Korea","volume":"53","author":"Kim","year":"2015","journal-title":"Korean J Parasitol."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1002\/0471142735.im1912s55","article-title":"Animal model of Nippostrongylus brasiliensis and Heligmosomoides polygyrus","author":"Camberis","year":"2003","journal-title":"Curr Protoc Immunol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1002\/cpmo.34","article-title":"The study of host immune responses elicited by the model murine hookworms Nippostrongylus brasiliensis and Heligmosomoides polygyrus","volume":"7","author":"Bouchery","year":"2017","journal-title":"Curr Protoc Mouse Biol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"2059","DOI":"10.1084\/jem.20091903","article-title":"Regulation of pathogenesis and immunity in helminth infections","volume":"206","author":"Maizels","year":"2009","journal-title":"J Exp Med."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1126\/science.aaf1648","article-title":"Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut","volume":"351","author":"Howitt","year":"2016","journal-title":"Science."},{"key":"B9","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1038\/nature16527","article-title":"Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites","volume":"529","author":"Gerbe","year":"2016","journal-title":"Nature"},{"key":"B10","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1038\/nature16161","article-title":"Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit","volume":"529","author":"von Moltke","year":"2016","journal-title":"Nature."},{"key":"B11","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.it.2010.11.005","article-title":"To B or not to B: B cells and the Th2-type immune response to helminths","volume":"32","author":"Harris","year":"2011","journal-title":"Trends Immunol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"E5169","DOI":"10.1073\/pnas.1412663111","article-title":"Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion","volume":"111","author":"Schwartz","year":"2014","journal-title":"Proc Natl Acad Sci USA."},{"key":"B13","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1016\/S1074-7613(04)00107-4","article-title":"Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology","volume":"20","author":"Herbert","year":"2004","journal-title":"Immunity"},{"key":"B14","doi-asserted-by":"publisher","first-page":"3590","DOI":"10.4049\/jimmunol.1401155","article-title":"T cell-derived IL-4\/IL-13 protects mice against fatal Schistosoma mansoni infection independently of basophils","volume":"193","author":"Schwartz","year":"2014","journal-title":"J Immunol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1038\/nri2992","article-title":"Diversity and dialogue in immunity to helminths","volume":"11","author":"Allen","year":"2011","journal-title":"Nat Rev Immunol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/j.immuni.2017.09.015","article-title":"HpARI protein secreted by a helminth parasite suppresses interleukin-33","volume":"47","author":"Osbourn","year":"2017","journal-title":"Immunity."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1038\/mi.2013.123","article-title":"Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy","volume":"7","author":"McSorley","year":"2014","journal-title":"Mucosal Immunol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"e54017","DOI":"10.7554\/eLife.54017","article-title":"A helminth-derived suppressor of ST2 blocks allergic responses","volume":"9","author":"Vacca","year":"2020","journal-title":"Elife."},{"key":"B19","doi-asserted-by":"publisher","first-page":"e1003531","DOI":"10.1371\/journal.ppat.1003531","article-title":"IL-1\u03b2 suppresses innate IL-25 and IL-33 production and maintains helminth chronicity","volume":"9","author":"Zaiss","year":"2013","journal-title":"PLoS Pathog."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1741","DOI":"10.1038\/s41467-017-01886-6","article-title":"A structurally distinct TGF-\u03b2 mimic from an intestinal helminth parasite potently induces regulatory T cells","volume":"8","author":"Johnston","year":"2017","journal-title":"Nat Commun."},{"key":"B21","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.ijpara.2017.12.004","article-title":"TGF-\u03b2 mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus","volume":"48","author":"Smyth","year":"2018","journal-title":"Int J Parasitol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"2331","DOI":"10.1084\/jem.20101074","article-title":"Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-\u03b2 pathway","volume":"207","author":"Grainger","year":"2010","journal-title":"J Exp Med."},{"key":"B23","doi-asserted-by":"publisher","first-page":"2473","DOI":"10.4049\/jimmunol.1801392","article-title":"Heligmosomoides polygyrus bakeri infection decreases smad7 expression in intestinal CD4(+) T cells, which allows TGF-\u03b2 to induce IL-10-producing regulatory T cells that block colitis","volume":"202","author":"Hang","year":"2019","journal-title":"J Immunol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"eaay0605","DOI":"10.1126\/scitranslmed.aay0605","article-title":"An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products","volume":"12","author":"de Los Reyes Jimenez","year":"2020","journal-title":"Sci Transl Med"},{"key":"B25","doi-asserted-by":"publisher","first-page":"2344","DOI":"10.1038\/s41467-019-09996-z","article-title":"The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function","volume":"10","author":"Bancroft","year":"2019","journal-title":"Nat Commun."},{"key":"B26","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1111\/j.1365-2222.2005.02268.x","article-title":"Modulation of murine experimental asthma by Ascaris suum components","volume":"35","author":"Itami","year":"2005","journal-title":"Clin Exp Allergy."},{"key":"B27","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s00011-004-1316-7","article-title":"Anti-inflammatory activity of PAS-1, a protein component of Ascaris suum","volume":"54","author":"Oshiro","year":"2005","journal-title":"Inflamm Res"},{"key":"B28","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1016\/j.cyto.2008.09.005","article-title":"PAS-1, a protein from Ascaris suum, modulates allergic inflammation via IL-10 and IFN-gamma, but not IL-12","volume":"44","author":"Araujo","year":"2008","journal-title":"Cytokine."},{"key":"B29","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1111\/j.1440-1711.2005.01404.x","article-title":"PAS-1, a protein affinity purified from Ascaris suum worms, maintains the ability to modulate the immune response to a bystander antigen","volume":"84","author":"Oshiro","year":"2006","journal-title":"Immunol Cell Biol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1111\/imm.12049","article-title":"Modulation of dendritic cell function and immune response by cysteine protease inhibitor from murine nematode parasite Heligmosomoides polygyrus","volume":"138","author":"Sun","year":"2013","journal-title":"Immunology"},{"key":"B31","doi-asserted-by":"publisher","first-page":"2280","DOI":"10.3389\/fimmu.2019.02280","article-title":"Ascaris lumbricoides cystatin prevents development of allergic airway inflammation in a mouse model","volume":"10","author":"Coronado","year":"2019","journal-title":"Front Immunol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"e96069","DOI":"10.1371\/journal.pone.0096069","article-title":"Structural basis for the immunomodulatory function of cysteine protease inhibitor from human roundworm Ascaris lumbricoides","volume":"9","author":"Mei","year":"2014","journal-title":"PLoS ONE"},{"key":"B33","doi-asserted-by":"publisher","first-page":"7380","DOI":"10.1128\/IAI.69.12.7380-7386.2001","article-title":"Nippocystatin, a cysteine protease inhibitor from Nippostrongylus brasiliensis, inhibits antigen processing and modulates antigen-specific immune response","volume":"69","author":"Dainichi","year":"2001","journal-title":"Infect Immun."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1550","DOI":"10.3390\/molecules22091550","article-title":"Acetylcholinesterase and nicotinic acetylcholine receptors in schistosomes and other parasitic helminths","volume":"22","author":"You","year":"2017","journal-title":"Molecules"},{"key":"B35","doi-asserted-by":"publisher","first-page":"e1005998","DOI":"10.1371\/journal.ppat.1005998","article-title":"Modulation of the immune response by nematode secreted acetylcholinesterase revealed by heterologous expression in Trypanosoma musculi","volume":"12","author":"Vaux","year":"2016","journal-title":"PLoS Pathog"},{"key":"B36","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1086\/381901","article-title":"Cloning, yeast expression, isolation, and vaccine testing of recombinant ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum","volume":"189","author":"Goud","year":"2004","journal-title":"J Infect Dis"},{"key":"B37","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.exppara.2007.11.014","article-title":"Necator americanus: the Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro","volume":"118","author":"Bower","year":"2008","journal-title":"Exp Parasitol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1093\/infdis\/jiu451","article-title":"Probing of a human proteome microarray with a recombinant pathogen protein reveals a novel mechanism by which hookworms suppress B-cell receptor signaling","volume":"211","author":"Tribolet","year":"2015","journal-title":"J Infect Dis."},{"key":"B39","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/j.chom.2020.01.011","article-title":"Hookworms evade host immunity by secreting a deoxyribonuclease to degrade neutrophil extracellular traps","volume":"27","author":"Bouchery","year":"2020","journal-title":"Cell Host Microbe."},{"key":"B40","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/978-1-4419-1601-3_13","article-title":"Chemokine binding proteins encoded by pathogens","volume":"666","author":"Alcami","year":"2009","journal-title":"Adv Exp Med Biol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1084\/jem.20050955","article-title":"Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity","volume":"202","author":"Smith","year":"2005","journal-title":"J Exp Med."},{"key":"B42","doi-asserted-by":"publisher","first-page":"e00301","DOI":"10.1128\/IAI.00301-17","article-title":"H-IPSE is a pathogen-secreted host nucleus-infiltrating protein (infiltrin) expressed exclusively by the Schistosoma haematobium egg stage","volume":"85","author":"Pennington","year":"2017","journal-title":"Infect Immun"},{"key":"B43","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.molbiopara.2006.01.003","article-title":"IPSE\/alpha-1: a major immunogenic component secreted from Schistosoma mansoni eggs","volume":"147","author":"Schramm","year":"2006","journal-title":"Mol Biochem Parasitol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"2293","DOI":"10.3389\/fimmu.2018.02293","article-title":"Schistosoma mansoni egg-released IPSE\/alpha-1 dampens inflammatory cytokine responses via basophil interleukin (IL)-4 and IL-13","volume":"9","author":"Knuhr","year":"2018","journal-title":"Front Immunol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"e1007924","DOI":"10.1371\/journal.ppat.1007924","article-title":"Schistosoma mansoni soluble egg antigen (SEA) and recombinant omega-1 modulate induced CD4+ T-lymphocyte responses and HIV-1 infection in vitro","volume":"15","author":"Mouser","year":"2019","journal-title":"PLoS Pathog."},{"key":"B46","doi-asserted-by":"publisher","first-page":"18384","DOI":"10.1074\/jbc.M300497200","article-title":"Molecular characterization of an interleukin-4-inducing factor from Schistosoma mansoni eggs","volume":"278","author":"Schramm","year":"2003","journal-title":"J Biol Chem."},{"key":"B47","doi-asserted-by":"publisher","first-page":"22111","DOI":"10.1074\/jbc.M115.675066","article-title":"A crystallin fold in the interleukin-4-inducing principle of Schistosoma mansoni eggs (IPSE\/alpha-1) mediates IgE binding for antigen-independent basophil activation","volume":"290","author":"Meyer","year":"2015","journal-title":"J Biol Chem."},{"key":"B48","doi-asserted-by":"publisher","first-page":"2276","DOI":"10.1111\/j.1742-4658.2006.05242.x","article-title":"IPSE\/alpha-1, a major secretory glycoprotein antigen from schistosome eggs, expresses the lewis X motif on core-difucosylated N-glycans","volume":"273","author":"Wuhrer","year":"2006","journal-title":"FEBS J."},{"key":"B49","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1084\/jem.20082460","article-title":"Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses","volume":"206","author":"Everts","year":"2009","journal-title":"J Exp Med."},{"key":"B50","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1084\/jem.20111381","article-title":"Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor","volume":"209","author":"Everts","year":"2012","journal-title":"J Exp Med."},{"key":"B51","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1016\/j.ijpara.2015.08.005","article-title":"The Schistosoma mansoni T2 ribonuclease omega-1 modulates inflammasome-dependent IL-1beta secretion in macrophages","volume":"45","author":"Ferguson","year":"2015","journal-title":"Int J Parasitol."},{"key":"B52","doi-asserted-by":"publisher","first-page":"e2005504","DOI":"10.1371\/journal.pbio.2005504","article-title":"Dectin-1\/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses","volume":"16","author":"Kaisar","year":"2018","journal-title":"PLoS Biol."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3347\/kjp.2015.53.1.1","article-title":"Serine proteases of parasitic helminths","volume":"53","author":"Yang","year":"2015","journal-title":"Korean J Parasitol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"12912","DOI":"10.1038\/s41598-017-13141-5","article-title":"The human blood parasite Schistosoma mansoni expresses extracellular tegumental calpains that cleave the blood clotting protein fibronectin","volume":"7","author":"Wang","year":"2017","journal-title":"Sci Rep."},{"key":"B55","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1186\/s13071-019-3639-9","article-title":"Molecular characterization and functional analysis of the Schistosoma mekongi Ca(2+)-dependent cysteine protease (calpain)","volume":"12","author":"Chaimon","year":"2019","journal-title":"Parasite Vectors."},{"key":"B56","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1111\/imcb.12171","article-title":"Immunobiology of parasitic worm extracellular vesicles","volume":"96","author":"Eichenberger","year":"2018","journal-title":"Immunol Cell Biol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1016\/j.ijpara.2020.04.010","article-title":"The protein and microRNA cargo of extracellular vesicles from parasitic helminths - current status and research priorities","volume":"50","author":"Sotillo","year":"2020","journal-title":"Int J Parasitol"},{"key":"B58","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1111\/pim.12182","article-title":"Exosome-transported microRNAs of helminth origin: new tools for allergic and autoimmune diseases therapy?","volume":"37","author":"Siles-Lucas","year":"2015","journal-title":"Parasite Immunol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"8327","DOI":"10.1183\/13993003.congress-2015.OA292","article-title":"Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation","volume":"6","author":"Cohen","year":"2015","journal-title":"Nat Commun."},{"key":"B60","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/1476-9255-8-22","article-title":"Role of IL-33 in inflammation and disease","volume":"8","author":"Miller","year":"2011","journal-title":"J Inflamm."},{"key":"B61","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1038\/nri.2016.112","article-title":"Immunoregulation by members of the TGF\u03b2 superfamily","volume":"16","author":"Chen","year":"2016","journal-title":"Nat Rev Immunol."},{"key":"B62","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1152\/physrev.00015.2008","article-title":"Mammalian nicotinic acetylcholine receptors: from structure to function","volume":"89","author":"Albuquerque","year":"2009","journal-title":"Physiol Rev."},{"key":"B63","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1038\/nature01339","article-title":"Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation","volume":"421","author":"Wang","year":"2003","journal-title":"Nature."},{"key":"B64","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1016\/j.immuni.2009.09.019","article-title":"MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase","volume":"31","author":"Shaked","year":"2009","journal-title":"Immunity."},{"key":"B65","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1038\/labinvest.3780391","article-title":"Functional distinction between CXC chemokines, interleukin-8 (IL-8), and growth related oncogene (GRO)\u03b1 in neutrophil infiltration","volume":"82","author":"Fujiwara","year":"2002","journal-title":"Lab Invest."},{"key":"B66","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1124\/mi.10.5.3","article-title":"Fractalkine\/CX3CL1: a potential new target for inflammatory diseases","volume":"10","author":"Jones","year":"2010","journal-title":"Mol Interv."},{"key":"B67","doi-asserted-by":"publisher","first-page":"2759","DOI":"10.3389\/fimmu.2019.02759","article-title":"More than just attractive: how CCL2 influences myeloid cell behavior beyond chemotaxis","volume":"10","author":"Gschwandtner","year":"2019","journal-title":"Front Immunol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1111\/sji.12457","article-title":"C-type lectin receptor expression on human basophils and effects of allergen-specific immunotherapy","volume":"84","author":"Lundberg","year":"2016","journal-title":"Scand J Immunol."},{"key":"B69","doi-asserted-by":"publisher","first-page":"e0006446","DOI":"10.1371\/journal.pntd.0006446","article-title":"SmSP2: a serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties","volume":"12","author":"Leontovyc","year":"2018","journal-title":"PLoS Negl Trop Dis."},{"key":"B70","doi-asserted-by":"publisher","first-page":"61","DOI":"10.3389\/fimmu.2014.00061","article-title":"Helminth allergens, parasite-specific IgE, and its protective role in human immunity","volume":"5","author":"Fitzsimmons","year":"2014","journal-title":"Front Immunol."},{"key":"B71","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1128\/CMR.05040-11","article-title":"Helminth infections and host immune regulation","volume":"25","author":"McSorley","year":"2012","journal-title":"Clin Microbiol Rev."},{"key":"B72","doi-asserted-by":"publisher","first-page":"955","DOI":"10.1038\/nm1451","article-title":"Memory T(H)2 cells induce alternatively activated macrophages to mediate protection against nematode parasites","volume":"12","author":"Anthony","year":"2006","journal-title":"Nat Med."},{"key":"B73","doi-asserted-by":"publisher","first-page":"eaau3814","DOI":"10.1126\/sciimmunol.aau3814","article-title":"RELM\u03b1 -expressing macrophages protect against fatal lung damage and reduce parasite burden during helminth infection","volume":"4","author":"Krljanac","year":"2019","journal-title":"Sci Immunol"},{"key":"B74","doi-asserted-by":"publisher","first-page":"362ra143","DOI":"10.1126\/scitranslmed.aaf8807","article-title":"Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma","volume":"8","author":"Navarro","year":"2016","journal-title":"Sci Transl Med."},{"key":"B75","doi-asserted-by":"publisher","first-page":"104099","DOI":"10.1016\/j.micpath.2020.104099","article-title":"Is Ascaris lumbricoides a risk factor for development of asthma? A systematic review and meta-analysis","volume":"142","author":"Taghipour","year":"2020","journal-title":"Microb Pathog."},{"key":"B76","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1615\/CritRevImmunol.2016016545","article-title":"Role in allergic diseases of immunological cross-reactivity between allergens and homologues of parasite proteins","volume":"36","author":"da Costa Santiago","year":"2016","journal-title":"Crit Rev Immunol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"e12589","DOI":"10.1111\/pim.12589","article-title":"Parasites and allergy: observations from Africa","volume":"41","author":"Mpairwe","year":"2019","journal-title":"Parasite Immunol."},{"key":"B78","doi-asserted-by":"publisher","first-page":"2243","DOI":"10.1016\/j.celrep.2019.10.051","article-title":"Helminth infections suppress the efficacy of vaccination against seasonal influenza","volume":"29","author":"Hartmann","year":"2019","journal-title":"Cell Rep."},{"key":"B79","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1093\/infdis\/173.1.269","article-title":"Impairment of tetanus toxoid-specific Th1-like immune responses in humans infected with Schistosoma mansoni","volume":"173","author":"Sabin","year":"1996","journal-title":"J Infect Dis"},{"key":"B80","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/j.vetpar.2005.07.006","article-title":"Vaccines against veterinary helminths","volume":"132","author":"Hein","year":"2005","journal-title":"Vet Parasitol."},{"key":"B81","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1586\/14760584.2014.893195","article-title":"Vaccination against helminth parasite infections","volume":"13","author":"Hewitson","year":"2014","journal-title":"Expert Rev Vaccines."},{"key":"B82","doi-asserted-by":"publisher","first-page":"288","DOI":"10.3389\/fcimb.2020.00288","article-title":"Use of veterinary vaccines for livestock as a strategy to control foodborne parasitic diseases","volume":"10","author":"Sander","year":"2020","journal-title":"Front Cell Infect Microbiol."}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2020.572865\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T05:09:37Z","timestamp":1600319377000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2020.572865\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,17]]},"references-count":82,"alternative-id":["10.3389\/fimmu.2020.572865"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2020.572865","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,17]]},"article-number":"572865"}}