{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:02:34Z","timestamp":1790622154532,"version":"4.1.0"},"reference-count":73,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T00:00:00Z","timestamp":1600387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008725","name":"Agencia Nacional de Investigaci\u00f3n e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["FCE_1_2017_1_136094"],"award-info":[{"award-number":["FCE_1_2017_1_136094"]}],"id":[{"id":"10.13039\/100008725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008725","name":"Agencia Nacional de Investigaci\u00f3n e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["FCE_1_2019_1_156295"],"award-info":[{"award-number":["FCE_1_2019_1_156295"]}],"id":[{"id":"10.13039\/100008725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2020.579801","type":"journal-article","created":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T05:18:39Z","timestamp":1600406319000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":19,"title":["Eosinophils Control Liver Damage by Modulating Immune Responses Against Fasciola hepatica"],"prefix":"10.3389","volume":"11","author":[{"given":"Sof\u00eda","family":"Frigerio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"da Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Florencia","family":"Festari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercedes","family":"Landeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago A.","family":"Rodr\u00edguez-Zraquia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"H\u00e4rtel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge","family":"Toledo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Freire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1007\/978-3-030-18616-6_4","article-title":"Fascioliasis.","volume":"1154","author":"Mas-Coma","year":"2019","journal-title":"Adv Exp Med Biol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1111\/pim.12343","article-title":"A prospective view of animal and human Fasciolosis.","volume":"38","author":"Cwiklinski","year":"2016","journal-title":"Parasite Immunol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.exppara.2016.07.010","article-title":"Controversial aspects of the life cycle of Fasciola hepatica.","volume":"169","author":"Moazeni","year":"2016","journal-title":"Exp Parasitol."},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00264","article-title":"Fasciola hepatica immune regulates CD11c(+) cells by interacting with the macrophage Gal\/GalNAc lectin.","volume":"8","author":"Rodriguez","year":"2017","journal-title":"Front Immunol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1128\/IAI.00573-09","article-title":"Major secretory antigens of the helminth Fasciola hepatica activate a suppressive dendritic cell phenotype that attenuates Th17 cells but fails to activate Th2 immune responses.","volume":"78","author":"Dowling","year":"2010","journal-title":"Infect Immun."},{"key":"B6","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1111\/pim.12127","article-title":"Fasciola hepatica tegumental antigens indirectly induce an M2 macrophage-like phenotype in vivo.","volume":"36","author":"Adams","year":"2014","journal-title":"Parasite Immunol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.4049\/jimmunol.0803803","article-title":"Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses.","volume":"183","author":"Walsh","year":"2009","journal-title":"J Immunol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1159\/000445215","article-title":"Player and coordinator: the versatile roles of eosinophils in the immune system.","volume":"43","author":"Long","year":"2016","journal-title":"Transfus Med Hemother."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.2174\/092986712799828337","article-title":"Granulocytes in helminth infection\u2013who is calling the shots?","volume":"19","author":"Makepeace","year":"2012","journal-title":"Curr Med Chem."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-28371-4","article-title":"Eosinophils support adipocyte maturation and promote glucose tolerance in obesity.","volume":"8","author":"Lee","year":"2018","journal-title":"Sci Rep."},{"key":"B11","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1038\/ni.1981","article-title":"Eosinophils are required for the maintenance of plasma cells in the bone marrow.","volume":"12","author":"Chu","year":"2011","journal-title":"Nat Immunol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"2055","DOI":"10.1084\/jem.20172049","article-title":"Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation.","volume":"215","author":"Arnold","year":"2018","journal-title":"J Exp Med."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1093\/infdis\/jix494","article-title":"Identification of a novel subset of myeloid-derived suppressor cells during chronic staphylococcal infection that resembles immature eosinophils.","volume":"216","author":"Goldmann","year":"2017","journal-title":"J Infect Dis."},{"key":"B14","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.jaci.2003.10.050","article-title":"The role of eosinophils in host defense against helminth parasites.","volume":"113","author":"Klion","year":"2004","journal-title":"J Allergy Clin Immunol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1084\/jem.147.1.147","article-title":"Complement-mediated killing of schistosomula of Schistosoma mansoni by rat eosinophils in vitro.","volume":"147","author":"Ramalho-Pinto","year":"1978","journal-title":"J Exp Med."},{"key":"B16","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1046\/j.1365-3024.2001.00352.x","article-title":"Involvement of complement and fibronectin in eosinophil-mediated damage to Nippostrongylus brasiliensis larvae.","volume":"23","author":"Shin","year":"2001","journal-title":"Parasite Immunol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1016\/j.ijpara.2007.04.006","article-title":"Impaired resistance in early secondary Nippostrongylus brasiliensis infections in mice with defective eosinophilopoeisis.","volume":"37","author":"Knott","year":"2007","journal-title":"Int J Parasitol."},{"key":"B18","doi-asserted-by":"crossref","first-page":"3911","DOI":"10.4049\/jimmunol.145.11.3911","article-title":"Ablation of eosinophil and IgE responses with anti-IL-5 or anti-IL-4 antibodies fails to affect immunity against Schistosoma mansoni in the mouse.","volume":"145","author":"Sher","year":"1990","journal-title":"J Immunol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1038\/mi.2016.93","article-title":"Eosinophils are required to suppress Th2 responses in Peyer\u2019s patches during intestinal infection by nematodes.","volume":"10","author":"Strandmark","year":"2017","journal-title":"Mucosal Immunol."},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00883","article-title":"Heme-oxygenase-1 expression contributes to the immunoregulation induced by Fasciola hepatica and promotes infection.","volume":"8","author":"Carasi","year":"2017","journal-title":"Front Immunol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"925","DOI":"10.7150\/ijms.8951","article-title":"Alanine aminotransferase-old biomarker and new concept: a review.","volume":"11","author":"Liu","year":"2014","journal-title":"Int J Med Sci."},{"key":"B22","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/s41423-019-0210-8","article-title":"Orchestration between ILC2s and Th2 cells in shaping type 2 immune responses.","volume":"16","author":"Gurram","year":"2019","journal-title":"Cell Mol Immunol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/s00430-002-0156-8","article-title":"Cytokine-dependent inflammatory cell recruitment patterns in the peritoneal cavity of mice exposed to the parasitic nematode Brugia malayi.","volume":"192","author":"MacDonald","year":"2003","journal-title":"Med Microbiol Immunol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"2714","DOI":"10.1016\/j.molimm.2009.05.016","article-title":"The roles of eotaxin and the STAT6 signalling pathway in eosinophil recruitment and host resistance to the nematodes Nippostrongylus brasiliensis and Heligmosomoides bakeri.","volume":"46","author":"Knott","year":"2009","journal-title":"Mol Immunol."},{"key":"B25","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.actatropica.2009.10.017","article-title":"Anti-CCR3 monoclonal antibody inhibits eosinophil infiltration in Angiostrongylus cantonensis-infected ICR mice.","volume":"113","author":"Chuang","year":"2010","journal-title":"Acta Trop."},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-018-1071-2","article-title":"Chi3l3: a potential key orchestrator of eosinophil recruitment in meningitis induced by Angiostrongylus cantonensis.","volume":"15","author":"Wan","year":"2018","journal-title":"J Neuroinflamm."},{"key":"B27","doi-asserted-by":"publisher","first-page":"283","DOI":"10.4049\/jimmunol.1402219","article-title":"Eosinophils mediate protective immunity against secondary nematode infection.","volume":"194","author":"Huang","year":"2015","journal-title":"J Immunol."},{"key":"B28","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1079\/joh2003187","article-title":"Strongyloides ratti: the role of interleukin-5 in protection against tissue migrating larvae and intestinal adult worms.","volume":"77","author":"Watanabe","year":"2003","journal-title":"J Helminthol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1365-3024.2010.01246.x","article-title":"Accumulation of eosinophils in intestine-draining mesenteric lymph nodes occurs after Trichuris muris infection.","volume":"33","author":"Svensson","year":"2011","journal-title":"Parasite Immunol."},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.03019","article-title":"Identification of piecemeal degranulation and vesicular transport of MBP-1 in liver-infiltrating mouse eosinophils during acute experimental Schistosoma mansoni infection.","volume":"9","author":"Dias","year":"2018","journal-title":"Front Immunol."},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003988","article-title":"Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae.","volume":"10","author":"Cadman","year":"2014","journal-title":"PLoS Pathog."},{"key":"B32","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1002\/eji.200425541","article-title":"Eotaxin-1-regulated eosinophils have a critical role in innate immunity against experimental Brugia malayi infection.","volume":"35","author":"Simons","year":"2005","journal-title":"Eur J Immunol."},{"key":"B33","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.exppara.2003.09.001","article-title":"Impaired clearance of primary but not secondary Brugia infections in IL-5 deficient mice.","volume":"105","author":"Ramalingam","year":"2003","journal-title":"Exp Parasitol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1128\/iai.67.2.989-993.1999","article-title":"Interleukin-5 transgenic mice show enhanced resistance to primary infections with Nippostrongylus brasiliensis but not primary infections with Toxocara canis.","volume":"67","author":"Dent","year":"1999","journal-title":"Infect Immun."},{"key":"B35","doi-asserted-by":"publisher","first-page":"2420","DOI":"10.1182\/blood-2006-04-015933","article-title":"Schistosoma mansoni infection in eosinophil lineage-ablated mice.","volume":"108","author":"Swartz","year":"2006","journal-title":"Blood."},{"key":"B36","doi-asserted-by":"publisher","first-page":"5513","DOI":"10.1073\/pnas.88.13.5513","article-title":"Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice.","volume":"88","author":"Urban","year":"1991","journal-title":"Proc Natl Acad Sci USA."},{"key":"B37","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.4049\/jimmunol.182.3.1577","article-title":"Eosinophil deficiency compromises parasite survival in chronic nematode infection.","volume":"182","author":"Fabre","year":"2009","journal-title":"J Immunol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1016\/0020-7519(94)90159-7","article-title":"Regulatory effect of anti-interleukin-5 monoclonal antibody on intestinal worm burden in a primary infection with strongyloides venezuelensis in mice.","volume":"24","author":"Korenaga","year":"1994","journal-title":"Int J Parasitol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1046\/j.1365-3024.1997.d01-210.x","article-title":"Eosinophilic interleukin 5 (IL-5) transgenic mice: eosinophil activity and impaired clearance of Schistosoma mansoni.","volume":"19","author":"Dent","year":"1997","journal-title":"Parasite Immunol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/s0034-5288(18)31908-8","article-title":"Early migration of immature Fasciola hepatica and associated liver pathology in cattle.","volume":"37","author":"Doy","year":"1984","journal-title":"Res Vet Sci."},{"key":"B41","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/s0034-5288(18)33819-0","article-title":"The recovery after oral infection of immature Fasciola hepatica from the peritoneal cavity of two strains of mice.","volume":"15","author":"Harness","year":"1973","journal-title":"Res Vet Sci."},{"key":"B42","doi-asserted-by":"publisher","first-page":"F1000FacultyRev","DOI":"10.12688\/f1000research.13943.1","article-title":"Managing portal hypertension in patients with liver cirrhosis.","volume":"7","author":"Sauerbruch","year":"2018","journal-title":"F1000Res."},{"key":"B43","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1016\/j.jhep.2013.01.015","article-title":"Hemorrhagic ascites. Clinical presentation and outcomes in patients with cirrhosis.","volume":"58","author":"Urrunaga","year":"2013","journal-title":"J Hepatol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"349","DOI":"10.5152\/tjg.2016.160042","article-title":"Cirrhosis with ascites: is the presence of hemorrhagic ascites an indicator of poor prognosis?","volume":"27","author":"Yildiz","year":"2016","journal-title":"Turk J Gastroenterol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1046\/j.1365-3024.2000.00328.x","article-title":"Interleukin-5 deficient mice exhibit impaired host defence against challenge Trichinella spiralis infections.","volume":"22","author":"Vallance","year":"2000","journal-title":"Parasite Immunol."},{"key":"B46","doi-asserted-by":"crossref","first-page":"3642","DOI":"10.4049\/jimmunol.149.11.3642","article-title":"Depletion of eosinophils by anti-IL-5 monoclonal antibody treatment of mice infected with Trichinella spiralis does not alter parasite burden or immunologic resistance to reinfection.","volume":"149","author":"Herndon","year":"1992","journal-title":"J Immunol."},{"key":"B47","first-page":"502","article-title":"The role of interleukin-5 in protective immunity to Strongyloides venezuelensis infection in mice.","volume":"72","author":"Korenaga","year":"1991","journal-title":"Immunology."},{"key":"B48","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1111\/sji.12477","article-title":"Neutrophil receptor response to bacterial N-formyl peptides is similar in term newborn infants and adults in contrast to IL-8.","volume":"84","author":"Stalhammar","year":"2016","journal-title":"Scand J Immunol."},{"key":"B49","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.biocel.2016.09.009","article-title":"CD44: more than a mere stem cell marker.","author":"Morath","year":"2016","journal-title":"Int J Biochem Cell Biol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1111\/cea.12292","article-title":"Activation states of blood eosinophils in asthma.","volume":"44","author":"Johansson","year":"2014","journal-title":"Clin Exp Allergy."},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11111664","article-title":"IL-33 Promotes CD11b\/CD18-mediated adhesion of eosinophils to cancer cells and synapse-polarized degranulation leading to tumor cell killing.","volume":"11","author":"Andreone","year":"2019","journal-title":"Cancers (Basel)."},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2017.00093","article-title":"The biology of eosinophils and their role in asthma.","volume":"4","author":"McBrien","year":"2017","journal-title":"Front Med (Lausanne)."},{"key":"B53","doi-asserted-by":"publisher","first-page":"5439","DOI":"10.4049\/jimmunol.175.8.5439","article-title":"Nonpathogenic, environmental fungi induce activation and degranulation of human eosinophils.","volume":"175","author":"Inoue","year":"2005","journal-title":"J Immunol."},{"key":"B54","doi-asserted-by":"publisher","first-page":"2268","DOI":"10.4049\/jimmunol.1101008","article-title":"SIRPalpha\/CD172a regulates eosinophil homeostasis.","volume":"187","author":"Verjan Garcia","year":"2011","journal-title":"J Immunol."},{"key":"B55","first-page":"584","article-title":"Human eosinophils as antigen-presenting cells: relative efficiency for superantigen- and antigen-induced CD4+ T-cell proliferation.","volume":"81","author":"Mawhorter","year":"1994","journal-title":"Immunology."},{"key":"B56","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.it.2018.11.001","article-title":"Professional and \u2018Amateur\u2019 antigen-presenting cells in type 2 immunity.","volume":"40","author":"Schuijs","year":"2019","journal-title":"Trends Immunol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1046\/j.1365-3024.2000.00290.x","article-title":"Fasciola hepatica infection downregulates Th1 responses in mice.","volume":"22","author":"O\u2019Neill","year":"2000","journal-title":"Parasite Immunol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"1673","DOI":"10.1016\/j.ijpara.2008.05.008","article-title":"The roles of IL-10 and TGF-beta in controlling IL-4 and IFN-gamma production during experimental Fasciola hepatica infection.","volume":"38","author":"Flynn","year":"2008","journal-title":"Int J Parasitol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"5236","DOI":"10.1128\/IAI.00329-06","article-title":"Lack of eosinophil peroxidase or major basic protein impairs defense against murine filarial infection.","volume":"74","author":"Specht","year":"2006","journal-title":"Infect Immun."},{"key":"B60","doi-asserted-by":"publisher","first-page":"6287","DOI":"10.1128\/IAI.72.11.6287-6293.2004","article-title":"Interleukin-10 (IL-10) counterregulates IL-4-dependent effector mechanisms in Murine Filariasis.","volume":"72","author":"Specht","year":"2004","journal-title":"Infect Immun."},{"key":"B61","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1189\/jlb.3A0916-221RR","article-title":"IL-10 distinguishes a unique population of activated, effector-like CD8(+) T cells in murine acute liver inflammation.","volume":"101","author":"Rood","year":"2017","journal-title":"J Leukoc Biol."},{"key":"B62","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.ijpara.2009.06.008","article-title":"Dynamics of hepatic stellate cells, collagen types I and III synthesis and gene expression of selected cytokines during hepatic fibrogenesis following Mesocestoides vogae (Cestoda) infection in mice.","volume":"40","author":"Hrckova","year":"2010","journal-title":"Int J Parasitol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1111\/pim.12303","article-title":"Production of interleukins 4 and 10 in children with hepatic involvement in the course of Toxocara spp. infection.","volume":"38","author":"Mazur-Melewska","year":"2016","journal-title":"Parasite Immunol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1590\/s0074-02761992000800025","article-title":"Effector functions of eosinophils in schistosomiasis.","author":"Capron","year":"1992","journal-title":"Mem Inst Oswaldo Cruz."},{"key":"B65","doi-asserted-by":"publisher","first-page":"842","DOI":"10.4269\/ajtmh.1980.29.842","article-title":"Mechanism of the interaction mediating killing of Schistosoma mansoni by human eosinophils.","volume":"29","author":"David","year":"1980","journal-title":"Am J Trop Med Hyg."},{"key":"B66","doi-asserted-by":"crossref","first-page":"716","DOI":"10.4049\/jimmunol.127.2.716","article-title":"IgE antibody in eosinophil- and macrophage-mediated in vitro killing of Dipetalonema viteae microfilariae.","volume":"127","author":"Haque","year":"1981","journal-title":"J Immunol."},{"key":"B67","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1038\/274588a0","article-title":"Stage-specific antibody-dependent eosinophil-mediated destruction of Trichinella spiralis.","volume":"274","author":"Kazura","year":"1978","journal-title":"Nature."},{"key":"B68","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1017\/s0031182000062703","article-title":"Ultrastructural observations on the interaction in vitro between bovine eosinophils and juvenile Fasciola hepatica.","author":"Glauert","year":"1985","journal-title":"Parasitology."},{"key":"B69","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1046\/j.1365-3024.1998.00144.x","article-title":"Protection of Fasciola hepatica in the gut mucosa of immune rats is associated with infiltrates of eosinophils, IgG1 and IgG2a antibodies around the parasites.","volume":"20","author":"Van Milligen","year":"1998","journal-title":"Parasite Immunol."},{"key":"B70","first-page":"336","article-title":"Killing of juvenile Fasciola hepatica by purified bovine eosinophil proteins.","volume":"40","author":"Duffus","year":"1980","journal-title":"Clin Exp Immunol."},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-015-1219-1","article-title":"Leucocyte-derived extracellular trap formation significantly contributes to Haemonchus contortus larval entrapment.","volume":"8","author":"Munoz-Caro","year":"2015","journal-title":"Parasit Vectors."},{"key":"B72","doi-asserted-by":"publisher","first-page":"5640","DOI":"10.1182\/blood-2012-01-380121","article-title":"Properties of mouse and human IgG receptors and their contribution to disease models.","volume":"119","author":"Bruhns","year":"2012","journal-title":"Blood."},{"key":"B73","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/s0169-4758(99)01620-8","article-title":"The role of eosinophils in parasitic helminth infections: insights from genetically modified mice.","volume":"16","author":"Behm","year":"2000","journal-title":"Parasitol Today."}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2020.579801\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T13:54:04Z","timestamp":1696686844000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fimmu.2020.579801\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,18]]},"references-count":73,"alternative-id":["10.3389\/fimmu.2020.579801"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2020.579801","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,18]]},"article-number":"579801"}}