{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:57:39Z","timestamp":1753891059119,"version":"3.41.2"},"reference-count":80,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T00:00:00Z","timestamp":1631232000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"abstract":"<jats:p>The presence of anti-desmocollin (Dsc) antibodies is rarely described in autoimmune blistering diseases patients. Moreover, several clinical phenotypes of pemphigus may be associated with these antibodies. In this review we analyze clinicopathological, immunologic and outcome features of anti-Dsc autoimmune blistering diseases patients, to improve their diagnosis and management. We conducted a systematic search of PubMed and Embase (1990-present) for studies reporting cases of autoimmune blistering diseases with anti-Dsc antibodies. We classified the selected patients as patients with exclusively anti-Dsc autoantibodies, and patients with anti-Dsc and other autoantibodies. Of 93 cases with anti-Dsc autoantibodies included, 38 (41%) had exclusively these antibodies. Only 18% of patients presented with the typical clinicopathological phenotype of pemphigus vulgaris or pemphigus foliaceous. Mucosal involvement was seen in approximately half of the patients. Up to 18% of cases were associated with neoplasms. Acantholysis was described in 54% of cases with histopathological information. Treatments and outcomes vary in the different clinical phenotypes. The presence of anti-Dsc antibodies must be suspected mainly in those patients with either atypical pemphigus, in special with clinical pustules, or in cases showing intraepithelial or dermal neutrophilic\/eosinophilic infiltrate on histological examination and dual pattern by direct immunofluorescence examination.<\/jats:p>","DOI":"10.3389\/fimmu.2021.740820","type":"journal-article","created":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T05:59:43Z","timestamp":1631253583000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Anti-Desmocollin Autoantibodies in Autoimmune Blistering Diseases"],"prefix":"10.3389","volume":"12","author":[{"given":"Xavier","family":"Bosch-Amate","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar","family":"Iranzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Ivars","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Manuel","family":"Mascar\u00f3 Galy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agust\u00edn","family":"Espa\u00f1a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,9,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.06.022","article-title":"Mechanisms Causing Loss of Keratinocyte Cohesion in Pemphigus","volume":"138","author":"Spindler","year":"2018","journal-title":"J Invest Dermatol"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.11.075","article-title":"Intraepithelial Autoimmune Blistering Dermatoses: Clinical Features and Diagnosis","volume":"84","author":"Montagnon","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1080\/08916930600971554","article-title":"Significance of Autoimmunity to Non-Desmoglein Targets in Pemphigus","volume":"39","author":"Kurzen","year":"2006","journal-title":"Autoimmunity"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2021.06.017","article-title":"Human Desmocollin 3-Specific IgG Antibodies Are Pathogenic in a Humanized HLA-Class II Transgenic Mouse Model of Pemphigus","author":"Hudemann","year":"2021","journal-title":"J Invest Dermatol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA118.006743","article-title":"Synergy Among non-Desmoglein Antibodies Contributes to the Immunopathology of Desmoglein Antibody-Negative Pemphigus Vulgaris","volume":"294","author":"Chernyavsky","year":"2019","journal-title":"J Biol Chem"},{"key":"B6","doi-asserted-by":"publisher","first-page":"e57587","DOI":"10.1371\/journal.pone.0057587","article-title":"Pemphigus Vulgaris Autoantibody Profiling by Proteomic Technique","volume":"8","author":"Kalantari-Dehaghi","year":"2013","journal-title":"PloS One"},{"key":"B7","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1111\/bjd.13711","article-title":"Anti-Desmocollin Autoantibodies in Nonclassical Pemphigus","volume":"173","author":"Ishii","year":"2015","journal-title":"Br J Dermatol"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.100483","article-title":"Autoimmunity to Desmocollin 3 in Pemphigus Vulgaris","volume":"177","author":"Mao","year":"2010","journal-title":"Am J Pathol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"e8","DOI":"10.1016\/j.jaad.2009.09.016","article-title":"Antidesmocollin-1 Antibody\u2013Positive, Antidesmoglein Antibody\u2013Negative Pemphigus Herpetiformis","volume":"63","author":"Tateishi","year":"2010","journal-title":"J Am Acad Dermatol"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2010.10.016","article-title":"IgG Autoantibodies Against Desmocollin 3 in Pemphigus Sera Induce Loss of Keratinocyte Adhesion","volume":"178","author":"Rafei","year":"2011","journal-title":"Am J Pathol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2012.1762","article-title":"Atypical Pemphigus With Exclusively Anti-Desmocollin 3-Specific IgG Antibodies","volume":"22","author":"Hatano","year":"2012","journal-title":"Eur J Dermatol"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13088","article-title":"A Case of Pemphigus Herpetiformis-Like Atypical Pemphigus With IgG Anti-Desmocollin 3 Antibodies","volume":"171","author":"Nakamura","year":"2014","journal-title":"Br J Dermatol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"102","DOI":"10.5021\/ad.2016.28.1.102","article-title":"A Case of Pemphigus Herpetiformis With Only Immunoglobulin G Anti-Desmocollin 3 Antibodies","volume":"28","author":"Hong","year":"2016","journal-title":"Ann Dermatol"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12729","article-title":"Childhood Pemphigus Foliaceus With Exclusive Immunoglobulin G Autoantibodies to Desmocollins","volume":"33","author":"Geller","year":"2016","journal-title":"Pediatr Dermatol"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13451","article-title":"Case of Pemphigus Herpetiformis With Immunoglobulin G Autoantibodies Against Desmocollin-3","volume":"44","author":"Ansai","year":"2017","journal-title":"J Dermatol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"e226","DOI":"10.1111\/bjd.15954","article-title":"Image Gallery: Juvenile Autoimmune Pemphigus Presenting With Diffuse Gingival Hypertrophy and Antibodies Against Desmocollin 3","volume":"177","author":"Leventhal","year":"2017","journal-title":"Br J Dermatol"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13677","article-title":"Case of Shift From Linear Immunoglobulin A Bullous Dermatosis to Pemphigus Herpetiformis for a Short Period of Time","volume":"44","author":"Koga","year":"2017","journal-title":"J Dermatol"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2017.3202","article-title":"Reduced IgG Anti-Desmocollin Autoantibody Titre and Concomitant Improvement in a Patient With Pemphigus Vegetans","volume":"28","author":"Tani","year":"2018","journal-title":"Eur J Dermatol"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1111\/ced.13355","article-title":"Pemphigus Herpetiformis With Autoantibodies to Desmocollins 1, 2 and 3","volume":"43","author":"Tay","year":"2018","journal-title":"Clin Exp Dermatol"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15834","article-title":"Appearance of Antidesmocollin 1 Autoantibodies Leading to a Vegetative Lesion in a Patient With Pemphigus Vulgaris","volume":"178","author":"Yamaguchi","year":"2018","journal-title":"Br J Dermatol"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12991","article-title":"Nonclassical Pemphigus With Exclusively IgG Anti-Desmocollin 3-Specific Antibodies","volume":"60","author":"Iranzo","year":"2019","journal-title":"Australas J Dermatol"},{"key":"B22","article-title":"Subcorneal Pustulosis, Superficial Acantholysis and Monoclonal IgA","volume":"109","author":"Wallach","year":"1982","journal-title":"Ann Dermatol Venereol"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12319025","article-title":"Human Desmocollin 1 (Dsc1) Is an Autoantigen for the Subcorneal Pustular Dermatosis Type of IgA Pemphigus","volume":"109","author":"Hashimoto","year":"1997","journal-title":"J Invest Dermatol"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03604.x","article-title":"Subcorneal Pustular Dermatosis Type of IgA Pemphigus: Demonstration of Autoantibodies to Desmocollin-1 and Clinical Review","volume":"143","author":"Yasuda","year":"2000","journal-title":"Br J Dermatol"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.104002","article-title":"Rapid Response of IgA Pemphigus of Subcorneal Pustular Dermatosis Type to Treatment With Isotretinoin","volume":"43","author":"Gruss","year":"2000","journal-title":"J Am Acad Dermatol"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/S0001-7310(01)76485-X","article-title":"Dermatosis Pustulosa Subc\u00f3rnea Con Anticuerpos IgA Antidesmocolina","volume":"92","author":"Botella Estrada","year":"2001","journal-title":"Actas Dermo-Sifiliogr\u00e1ficas"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2002.01061.x","article-title":"Clinical, Histopathological and Immunological Distinction in Two Cases of IgA Pemphigus","volume":"27","author":"Hashimoto","year":"2002","journal-title":"Clin Exp Dermatol"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2002.504815.x","article-title":"Garc\u00eda-D\u00edez A. A Case of IgA Pemphigus Successfully Treated With Acitretin","volume":"147","author":"Ruiz-Genao","year":"2002","journal-title":"Br J Dermatol"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2003.tb00343.x","article-title":"Two Brazilian Cases of IgA Pemphigus","volume":"30","author":"de Oliveira","year":"2003","journal-title":"J Dermatol"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.11.023","article-title":"A Novel Case of IgA Paraneoplastic Pemphigus Associated With Chronic Lymphocytic Leukemia","volume":"56","author":"Taintor","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1111\/j.1365-2230.2009.03241.x","article-title":"Autoantibodies Against Desmocollins in European Patients With Pemphigus","volume":"34","author":"M\u00fcller","year":"2009","journal-title":"Clin Exp Dermatol"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.224","article-title":"Subcorneal Pustular Dermatosis\u2013Type IgA Pemphigus With Autoantibodies to Desmocollins 1, 2, and 3","volume":"145","author":"D\u00fcker","year":"2009","journal-title":"Arch Dermatol"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2012.11127.x","article-title":"IgA Pemphigus Associated With Diffuse Large B-Cell Lymphoma Showing Unique Reactivity With Desmocollins: Unusual Clinical and Histopathological Features","volume":"168","author":"Asahina","year":"2013","journal-title":"Br J Dermatol"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2013.2046","article-title":"IgA Pemphigus With non-Pustular Erythematous Lesions and IgA Antibodies to Desmocollins 1 and 2","volume":"23","author":"Arai","year":"2013","journal-title":"Eur J Dermatol"},{"key":"B35","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1001\/jamadermatol.2017.0901","article-title":"Annular Flaccid Pustules on the Trunk","volume":"153","author":"Kiritsi","year":"2017","journal-title":"JAMA Dermatol"},{"article-title":"A Case Report of Concurrent Pyostomatitis Vegetans-Like\/Intercellular IgA Dermatosis and Uveitic Macular Edema Reacting Exclusively With Desmocollins. A Possible Common Pathogenesis. Article accepted in press at Annals of Dermatology","year":"","author":"\u2021Bosch-Amate","key":"B36"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2005.22408.x","article-title":"Atypical IgA\/IgG Pemphigus Involving the Skin, Oral Mucosa, and Colon in a Child: A Novel Variant of IgA Pemphigus","volume":"22","author":"Bruckner","year":"2005","journal-title":"Pediatr Dermatol"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00994","article-title":"Clinical and Immunological Study of 30 Cases With Both IgG and IgA Anti-Keratinocyte Cell Surface Autoantibodies Toward the Definition of Intercellular IgG\/IgA Dermatosis","volume":"9","author":"Hashimoto","year":"2018","journal-title":"Front Immunol"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(94)70171-7","article-title":"Unusual Acantholytic Bullous Dermatosis Associated With Neoplasia and IgG and IgA Antibodies Against Bovine Desmocollins I and II","volume":"31","author":"Chorzelski","year":"1994","journal-title":"J Am Acad Dermatol"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07226.x","article-title":"Intraepidermal Neutrophilic IgA\/IgG Antidesmocollin 1 Pemphigus: Correspondence","volume":"154","author":"Heng","year":"2006","journal-title":"Br J Dermatol"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/0923-1811(94)90083-3","article-title":"Detection of Anti-Desmocollins I and II Autoantibodies in Two Cases of Hallopeau Type Pemphigus Vegetans by Immunoblot Analysis","volume":"7","author":"Hashimoto","year":"1994","journal-title":"J Dermatol Sci"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12606050","article-title":"A Case of Pemphigus Vulgaris Showing Reactivity With Pemphigus Antigens (Dsg1 and Dsg3) and Desmocollins","volume":"104","author":"Hashimoto","year":"1995","journal-title":"J Invest Dermatol"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.23","article-title":"Pemphigus Herpetiformis With IgA and IgG Antibodies to Desmoglein 1 and IgG Antibodies to Desmocollin 3","volume":"48","author":"Kozlowska","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2006.06166.x","article-title":"IgA Pemphigus\u00a0? Occurrence of Anti-Desmocollin 1 and Anti-Desmoglein 1 Antibody Reactivity in an Individual Patient","volume":"4","author":"Kopp","year":"2006","journal-title":"JDDG"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1258","article-title":"A Case of IgG\/IgA Pemphigus Presenting Malar Rash-Like Erythema","volume":"92","author":"Hosoda","year":"2012","journal-title":"Acta Derm Venerol"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.12.967","article-title":"Successful Single-Cycle Rituximab Treatment in a Patient With Pemphigus Vulgaris and Squamous Cell Carcinoma of the Tongue and IgG Antibodies to Desmocollins","volume":"69","author":"Kim","year":"2013","journal-title":"J Am Acad Dermatol"},{"key":"B47","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1001\/jamadermatol.2013.5244","article-title":"Two Cases of Pemphigus Vegetans With IgG Anti\u2013Desmocollin 3 Antibodies","volume":"149","author":"Saruta","year":"2013","journal-title":"JAMA Dermatol"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2012.05725.x","article-title":"Recalcitrant Pemphigus Herpetiformis With High Titer of Immunoglobulin G Antibody to Desmoglein 1 and Positive IgG Antibody to Desmocollin 3, Elevating Thymus and Activation-Regulated Chemokine","volume":"53","author":"Matsukura","year":"2014","journal-title":"Int J Dermatol"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13419","article-title":"Pemphigus Herpetiformis With IgG Autoantibodies to Desmoglein 1 and Desmocollin 1","volume":"172","author":"On","year":"2015","journal-title":"Br J Dermatol"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2015.2646","article-title":"Detection of IgG Antibodies to Desmoglein 3 and Desmocollins 2 and 3 in Mucosal Dominant-Type Pemphigus Vulgaris With Severe Pharyngalgia and Hyperemia of the Bulbar Conjunctiva","volume":"25","author":"Makino","year":"2015","journal-title":"Eur J Dermatol"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13086","article-title":"Atypical Pemphigus With Immunoglobulin G Autoantibodies Against Desmoglein 3 and Desmocollin 3","volume":"43","author":"Kamiya","year":"2016","journal-title":"J Dermatol"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1111\/ced.13670","article-title":"Elevated Serum Eosinophil Cationic Protein and Transforming Growth Factor-\u03b1 Levels in a Patient With Pemphigus Vegetans","volume":"43","author":"Matsuyama","year":"2018","journal-title":"Clin Exp Dermatol"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2020.3819","article-title":"Atypical Pemphigus With Anti-Desmocollin 2 and 3 Antibodies, Initially Presenting as Pemphigus Vulgaris With Anti-Desmoglein 3 Antibodies","volume":"30","author":"Shimokata-Isoe","year":"2020","journal-title":"Eur J Dermatol"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.03162.x","article-title":"Unique Immunobullous Disease in a Child With a Predominantly IgA Response to Three Desmosomal Proteins","volume":"141","author":"Gooptu","year":"1999","journal-title":"Br J Dermatol"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.05978.x","article-title":"Exacerbation of Paraneoplastic Pemphigus by Cyclophosphamide Treatment: Detection of Novel Autoantigens and Bronchial Autoantibodies","volume":"150","author":"Preisz","year":"2004","journal-title":"Br J Dermatol"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07920.x","article-title":"Acquired Palmoplantar Keratoderma and Immunobullous Disease Associated With Antibodies to Desmocollin 3","volume":"157","author":"Bolling","year":"2007","journal-title":"Br J Dermatol"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2010.1020","article-title":"Bullous Dermatosis Associated With IgG Antibodies Specific for Desmocollins","volume":"20","author":"Endo","year":"2010","journal-title":"Eur J Dermatol"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12398","article-title":"Unique Herpetiform Bullous Dermatosis With IgG Antibodies to Desmocollins 1\/3 and LAD-1","volume":"169","author":"Ueda","year":"2013","journal-title":"Br J Dermatol"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12050","article-title":"IgA Pemphigus With Paraneoplastic Pemphigus-Like Clinical Features Showing IgA Antibodies to Desmoglein 1\/3 and Desmocollin 3, and IgG and IgA Antibodies to the Basement Membrane Zone","volume":"38","author":"Ueda","year":"2013","journal-title":"Clin Exp Dermatol"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.1916","article-title":"Coexistence of Pemphigus Herpetiformis With IgG Antibodies to Desmocollin 1 and Pemphigoid With IgG Antibodies to BP180 C-Terminal Domain and Laminin \u03b32","volume":"149","author":"Ohata","year":"2013","journal-title":"JAMA Dermatol"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12019","article-title":"Concurrence of Bullous Pemphigoid and Herpetiform Pemphigus With IgG Antibodies to Desmogleins 1\/3 and Desmocollins 1-3: Correspondence","volume":"168","author":"Ohata","year":"2013","journal-title":"Br J Dermatol"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12296","article-title":"Paraneoplastic Pemphigus With Eosinophilic Spongiosis and Autoantibodies Against Desmocollins 2 and 3","volume":"39","author":"Gallo","year":"2014","journal-title":"Clin Exp Dermatol"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1660","article-title":"IgA Paraneoplastic Pemphigus in Angioimmunoblastic T-Cell Lymphoma With Antibodies to Desmocollin 1, Type VII Collagen and Laminin 332","volume":"94","author":"Yashiro","year":"2014","journal-title":"Acta Derm Venerol"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1836","article-title":"IgA\/IgG Pemphigus With Infiltration of Neutrophils and Eosinophils in an Ulcerative Colitis Patient","volume":"94","author":"Uchiyama","year":"2014","journal-title":"Acta Derm Venerol"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12940","article-title":"The Expanding Spectrum of IgA Pemphigus: A Case Report and Review of the Literature","volume":"171","author":"Geller","year":"2014","journal-title":"Br J Dermatol"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13617","article-title":"Presence of Autoimmune Regulator and Absence of Desmoglein 1 in a Thymoma in a Patient With Pemphigus Foliaceus","volume":"173","author":"Tsuchisaka","year":"2015","journal-title":"Br J Dermatol"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13158","article-title":"IgG\/IgA Pemphigus Representing Pemphigus Vegetans Caused by Low Titres of IgG and IgA Antibodies to Desmoglein 3 and IgA Antibodies to Desmocollin 3","volume":"30","author":"Inoue-Nishimoto","year":"2016","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.13341","article-title":"Case of Paraneoplastic Pemphigus With Immunoglobulin (Ig)G and IgA Antibodies to Various Antigens","volume":"43","author":"Otsuka","year":"2016","journal-title":"J Dermatol"},{"key":"B69","doi-asserted-by":"publisher","first-page":"219","DOI":"10.5021\/ad.2017.29.2.219","article-title":"Paraneoplastic Pemphigus Associated With a Malignant Thymoma: A Case of Persistent and Refractory Oral Ulcerations Following Thymectomy","volume":"29","author":"Lim","year":"2017","journal-title":"Ann Dermatol"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01413","article-title":"Thymoma-Associated Paraneoplastic Autoimmune Multiorgan Syndrome-From Pemphigus to Lichenoid Dermatitis","volume":"10","author":"Solimani","year":"2019","journal-title":"Front Immunol"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13025","article-title":"Clinicopathologic Features of IgG\/IgA Pemphigus in Comparison With Classic (IgG) and IgA Pemphigus","volume":"55","author":"Toosi","year":"2016","journal-title":"Int J Dermatol"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13409","article-title":"Routine Detection of Serum Antidesmocollin Autoantibodies is Only Useful in Patients With Atypical Pemphigus","volume":"26","author":"Mindorf","year":"2017","journal-title":"Exp Dermatol"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01387","article-title":"Development of a Desmocollin-3 Active Mouse Model Recapitulating Human Atypical Pemphigus","volume":"10","author":"Lotti","year":"2019","journal-title":"Front Immunol"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18382","article-title":"The Involvement of ADAM10 in Acantholysis in Mucocutaneous Pemphigus Vulgaris Depends on the Autoantibody Profile of Each Patient","volume":"182","author":"Ivars","year":"2020","journal-title":"Br J Dermatol"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14162","article-title":"Clinical and Immunological Findings in 104 Cases of Paraneoplastic Pemphigus","volume":"173","author":"Ohzono","year":"2015","journal-title":"Br J Dermatol"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14277","article-title":"Paraneoplastic Pemphigus: An Entity Still in Search of an Identity","volume":"173","author":"Sprecher","year":"2015","journal-title":"Br J Dermatol"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.00779","article-title":"Humoral Epitope Spreading in Autoimmune Bullous Diseases","volume":"9","author":"Didona","year":"2018","journal-title":"Front Immunol"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.11.059","article-title":"IgA Pemphigus: A Systematic Review","volume":"82","author":"Kridin","year":"2020","journal-title":"J Am Acad Dermatol"},{"key":"B79","first-page":"193","article-title":"Classification, Clinical Manifestations, and Immunopathological Mechanisms of the Epithelial Variant of Paraneoplastic Autoimmune Multiorgan Syndrome: A Reappraisal of Paraneoplastic Pemphigus","volume":"137","author":"Nguyen","year":"2001","journal-title":"Arch Dermatol"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1084\/jem.183.4.1579","article-title":"Localization of the Binding Site for the Monocyte Immunoglobulin (Ig) A-Fc Receptor (CD89) to the Domain Boundary Between Calpha2 and Calpha3 in Human Iga1","volume":"183","author":"Carayannopoulos","year":"1996","journal-title":"J Exp Med"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2021.740820\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,10]],"date-time":"2021-09-10T15:50:46Z","timestamp":1631289046000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2021.740820\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,10]]},"references-count":80,"alternative-id":["10.3389\/fimmu.2021.740820"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2021.740820","relation":{},"ISSN":["1664-3224"],"issn-type":[{"type":"electronic","value":"1664-3224"}],"subject":[],"published":{"date-parts":[[2021,9,10]]},"article-number":"740820"}}