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Recently, advanced imaging modalities, including ultrasonography (US), dual-energy computed tomography (DECT), and magnetic resonance imaging (MRI), attracted more and more attention for their role on gout as intuitive and non-invasive tools for early gout diagnosis and evaluation of therapeutic effect. This review summarized the role of US, DECT, and MRI in the management of gout from four perspectives: hyperuricemia, gout attacks, chronic gout, and gout complications described the scoring systems currently used to quantify disease severity and discussed the challenges and limitations of using these imaging tools to assess response to the gout treatment.<\/jats:p>","DOI":"10.3389\/fimmu.2021.811323","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T04:43:01Z","timestamp":1642135381000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":22,"title":["The Role of Advanced Imaging in Gout Management"],"prefix":"10.3389","volume":"12","author":[{"given":"Shuangshuang","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanhua","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junyu","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liyan","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heng","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,1,14]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40807","article-title":"Contemporary Prevalence of Gout and Hyperuricemia in the United States and Decadal Trends: The National Health and Nutrition Examination Survey, 2007-2016","volume":"71","author":"Chen-Xu","year":"2019","journal-title":"Arthritis Rheumatol"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-0441-1","article-title":"Global Epidemiology of Gout: Prevalence, Incidence, Treatment Patterns and Risk Factors","volume":"16","author":"Dehlin","year":"2020","journal-title":"Nat Rev Rheumatol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1002\/art.22466","article-title":"Prevalence of the Metabolic Syndrome in Patients With Gout: The Third National Health and Nutrition Examination Survey","volume":"57","author":"Choi","year":"2007","journal-title":"Arthritis Rheum"},{"key":"B4","article-title":"Pathologic Changes in Gout; Survey of Eleven Necropsied Cases","volume":"32","author":"Levin","year":"1956","journal-title":"Am J Pathol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.094201","article-title":"Mechanisms of Bone Erosion in Gout: A Quantitative Analysis Using Plain Radiography and Computed Tomography","volume":"68","author":"Dalbeth","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780180722","article-title":"Pathology of the Synovial Membrane in Gout. 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