{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T01:19:55Z","timestamp":1793841595694,"version":"4.6.1"},"reference-count":165,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T00:00:00Z","timestamp":1644451200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"abstract":"<jats:p>The modern Gastroenterology have witnessed an essential stride since <jats:italic>Helicobacter pylori<\/jats:italic> was first found in the stomach and then its pathogenic effect was discovered. According to the researches conducted during the nearly 40 years, it has been found that this bacterium is associated with a natural history of many upper gastrointestinal diseases. Epidemiological data show an increased incidence of autoimmune disorders with or after infection with specific microorganisms. The researches have revealed that <jats:italic>H. pylori<\/jats:italic> is a potential trigger of gastric autoimmunity, and it may be associated with other autoimmune diseases, both innate and acquired. This paper reviews the current support or opposition about <jats:italic>H. pylori<\/jats:italic> as the role of potential triggers of autoimmune diseases, including inflammatory bowel disease, autoimmune thyroiditis, type 1 diabetes mellitus, autoimmune liver diseases, rheumatoid arthritis, idiopathic thrombocytopenic purpura, systemic lupus erythematosus, as well as Sjogren\u2019s syndrome, chronic urticaria and psoriasis, and tried to explain the possible mechanisms.<\/jats:p>","DOI":"10.3389\/fimmu.2022.833424","type":"journal-article","created":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T07:34:53Z","timestamp":1644478493000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":91,"title":["Helicobacter Pylori and Autoimmune Diseases: Involving Multiple Systems"],"prefix":"10.3389","volume":"13","author":[{"given":"Li","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng-Min","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-can","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-ju","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-xian","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Ye","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-Juan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-liang","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,2,10]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002693","article-title":"Age of the Association Between Helicobacter Pylori and Man","volume":"8","author":"Moodley","year":"2012","journal-title":"PloS Pathog"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)92719-8","article-title":"Unidentified Curved Bacilli on Gastric Epithelium in Active Chronic Gastritis","volume":"1","author":"Warren","year":"1983","journal-title":"Lancet (Lond Engl)"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.04.022","article-title":"Global Prevalence of Helicobacter Pylori Infection: Systematic Review and Meta-Analysis","volume":"153","author":"Hooi","year":"2017","journal-title":"Gastroenterology"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1523-5378.2009.00703.x","article-title":"The Epidemiology of Helicobacter Pylori and Public Health Implications","volume":"14","author":"Azevedo","year":"2009","journal-title":"Helicobacter"},{"key":"B5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/hel.12165","article-title":"Epidemiology of Helicobacter Pylori Infection","volume":"19","author":"Eusebi","year":"2014","journal-title":"Helicobacter"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/hel.12403","article-title":"Epidemiology of Helicobacter Pylori Infection","volume":"22","author":"Burucoa","year":"2017","journal-title":"Helicobacter"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.epirev.a018040","article-title":"Helicobacter Pylori: Epidemiology and Routes of Transmission","volume":"22","author":"Brown","year":"2000","journal-title":"Epidemiol Rev"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2021.05.007","article-title":"Helicobacter Pylori: A Stealth Assassin","volume":"7","author":"Wroblewski","year":"2021","journal-title":"Trends Cancer"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1999.tb00012.x","article-title":"Clinical Symptoms and Social Factors in a Cohort of Children Spontaneously Clearing Helicobacter Pylori Infection","volume":"88","author":"Tindberg","year":"1999","journal-title":"Acta Paediatr"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-302084","article-title":"Management of Helicobacter Pylori Infection\u2013the Maastricht IV\/Florence Consensus Report","volume":"61","author":"Malfertheiner","year":"2012","journal-title":"GUT"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1007\/5584_2019_367","article-title":"Current and Future Treatment of Helicobacter Pylori Infections","volume":"1149","author":"Matsumoto","year":"2019","journal-title":"Adv Exp Med Biol"},{"key":"B12","first-page":"1","article-title":"Helicobacter Pylori: An Up-to-Date Overview on the Virulence and Pathogenesis Mechanisms","volume-title":"Braz J Microbiol","author":"Sharndama","year":"2022"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2018.02.016","article-title":"Influence of Helicobacter Pylori Virulence Factors CagA and VacA on Pathogenesis of Gastrointestinal Disorders","volume":"117","author":"Nejati","year":"2018","journal-title":"Microb Pathog"},{"key":"B14","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1080\/19490976.2015.1116673","article-title":"Systems-Wide Analyses of Mucosal Immune Responses to Helicobacter Pylori at the Interface Between Pathogenicity and Symbiosis","volume":"7","author":"Kronsteiner","year":"2016","journal-title":"Gut Microbes"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01168-17","article-title":"cagTIFA Signaling in Gastric Epithelial Cells Initiates the Type 4 Secretion System-Dependent Innate Immune Response to Infection","volume":"8","author":"Gall","year":"2017","journal-title":"MBIO"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2010.12.018","article-title":"Helicobacter Pylori Induction of Eosinophil Migration Is Mediated by the Cag Pathogenicity Island via Microbial-Epithelial Interactions","volume":"178","author":"Nagy","year":"2011","journal-title":"Am J Pathol"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0609014104","article-title":"Role of Peyer\u2019s Patches in the Induction of Helicobacter Pylori-Induced Gastritis","volume":"104","author":"Shigenori","year":"2007","journal-title":"P Natl Acad Sci USA"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-5378.2001.00043.x","article-title":"T Cell-Mediated Cytotoxicity via Fas\/Fas Ligand Signaling in Helicobacter Pylori-Infected Gastric Corpus","volume":"6","author":"Ishihara","year":"2001","journal-title":"Helicobacter"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.74.1.248-256.2006","article-title":"Implications for Induction of Autoimmunity via Activation of B-1 Cells by Helicobacter Pylori Urease","volume":"74","author":"Yamanishi","year":"2006","journal-title":"Infect Immun"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20030530","article-title":"Molecular Mimicry Between Helicobacter Pylori Antigens and H+, K+ \u2013Adenosine Triphosphatase in Human Gastric Autoimmunity","volume":"198","author":"Amedei","year":"2003","journal-title":"J Exp Med"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/315957","article-title":"Comparative Immune Response in Children and Adults With H. Pylori Infection","volume":"2015","author":"Alireza","year":"2015","journal-title":"J Immunol Res"},{"key":"B22","doi-asserted-by":"publisher","first-page":"377","DOI":"10.3390\/ijms19020377","article-title":"Autoimmunity and Gastric Cancer","volume":"19","author":"Bizzaro","year":"2018","journal-title":"Int J Mol Sci"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00039.2009","article-title":"Role of Innate Immunity in Helicobacter Pylori-Induced Gastric Malignancy","volume":"90","author":"Peek","year":"2010","journal-title":"Physiol Rev"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12107","article-title":"In Vitro Suppression of Dendritic Cells by Helicobacter Pylori OipA","volume":"19","author":"Omid","year":"2014","journal-title":"Helicobacter"},{"key":"B25","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.jaut.2013.01.008","article-title":"Genetic Susceptibility to SLE: Recent Progress From GWAS","volume":"41","author":"Cui","year":"2013","journal-title":"J Autoimmun"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2012-0477","article-title":"Helicobacter Pylori Serology in Autoimmune Diseases - Fact or Fiction","volume":"51","author":"Ram","year":"2013","journal-title":"Clin Chem Lab Med"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1172\/JCI12673","article-title":"Infection, Mimics, and Autoimmune Disease","volume":"107","author":"Rose","year":"2001","journal-title":"J Clin Invest"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-042617-053055","article-title":"Translating Immunology Into Therapeutic Concepts for Inflammatory Bowel Disease","volume":"36","author":"Uhlig","year":"2018","journal-title":"Annu Rev Immunol"},{"key":"B29","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1053\/j.gastro.2011.10.001","article-title":"Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review","volume":"142","author":"Molodecky","year":"2012","journal-title":"Gastroenterology"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-310545","article-title":"Dual Role of Helicobacter and Campylobacter Species in IBD: A Systematic Review and Meta-Analysis","volume":"66","author":"Casta\u00f1o-Rodr\u00edguez","year":"2017","journal-title":"GUT"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-313805","article-title":"Protective Effects of Helicobacter Pylori for IBD are Related to the cagA- Positive Strain","volume":"67","author":"Lord","year":"2018","journal-title":"GUT"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/17562848211004493","article-title":"The Role of Gastrointestinal Pathogens in Inflammatory Bowel Disease: A Systematic Review","volume":"14","author":"Axelrad","year":"2021","journal-title":"Ther Adv Gastroenter"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15770","article-title":"Systematic Review: Gastrointestinal Infection and Incident Inflammatory Bowel Disease","volume":"51","author":"Axelrad","year":"2020","journal-title":"Aliment Pharm Ther"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0248427","article-title":"The Prevalence of Helicobacter Pylori Infection in Inflammatory Bowel Disease in China: A Case-Control Study","volume":"16","author":"ZhaoHui","year":"2021","journal-title":"PloS One"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1177\/2050640615580889","article-title":"The Association Between Helicobacter Pylori Infection and Inflammatory Bowel Disease Based on Meta-Analysis","volume":"3","author":"Rokkas","year":"2015","journal-title":"United Eur Gastroent"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i15.4750","article-title":"Helicobacter Pylori Infection and Inflammatory Bowel Disease in Asians: A Meta-Analysis","volume":"21","author":"Xiao-Wei","year":"2015","journal-title":"World J Gastroentero"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_201912_19691","article-title":"Correlation Between Helicobacter Pylori Infection and Crohn\u2019s Disease: A Meta-Analysis","volume":"23","author":"Wang","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.04.016","article-title":"Environmental Risk Factors for Inflammatory Bowel Diseases: An Umbrella Review of Meta-Analyses","volume":"157","author":"Piovani","year":"2019","journal-title":"Gastroenterology"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.34172\/aim.2021.44","article-title":"The Relationship Between Helicobacter Pylori and Inflammatory Bowel Disease","volume":"24","author":"Yufen","year":"2021","journal-title":"Arch Iran Med"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.5217\/ir.2018.00044","article-title":"Seven Days Triple Therapy for Eradication of Helicobacter Pylori Does Not Alter the Disease Activity of Patients With Inflammatory Bowel Disease","volume":"16","author":"Shinichiro","year":"2018","journal-title":"Intest Res"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.15403\/jgld.2014.1121.272.hpy","article-title":"Helicobacter Pylori Eradication Therapy is Not Associated With the Onset of Inflammatory Bowel Diseases. A Case-Control Study","volume":"27","author":"Rosa","year":"2018","journal-title":"J Gastrointestinal Liver Dis: JGLD"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.34172\/aim.2021.44","article-title":"The Relationship Between Inflammatory Bowel Disease and Helicobacter Pylori Across East Asian, European and Mediterranean Countries: A Meta-Analysis","volume":"33","author":"Addawiyah","year":"2020","journal-title":"Ann Gastroenterol"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1111\/apt.16703","article-title":"Systematic Review With Meta-Analysis: Environmental and Dietary Differences of Inflammatory Bowel Disease in Eastern and Western Populations","volume":"55","author":"Zhao","year":"2022","journal-title":"Aliment Pharmacol Ther"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-019-05972-1","article-title":"Upper Gastrointestinal Disease Influences the Occurrence of Inflammatory Bowel Disease","volume":"65","author":"Sonnenberg","year":"2020","journal-title":"Digest Dis Sci"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000318","article-title":"Helicobacter Pylori-Specific Protection Against Inflammatory Bowel Disease Requires the NLRP3 Inflammasome and IL-18","volume":"21","author":"Engler","year":"2015","journal-title":"Inflamm Bowel Dis"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i21.6374","article-title":"Helicobacter Pylori Infection and Inflammatory Bowel Disease: Is There a Link","volume":"20","author":"Papamichael","year":"2014","journal-title":"World J Gastroentero"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15306","article-title":"Systematic Review With Meta-Analysis: Association Between Helicobacter Pylori CagA Seropositivity and Odds of Inflammatory Bowel Disease","volume":"50","author":"Tepler","year":"2019","journal-title":"Aliment Pharmacol Ther"},{"key":"B48","article-title":"Autoimmune Thyroid Disease: Mechanism, Genetics and Current Knowledge","volume":"18","author":"Dong","year":"2014","journal-title":"Eur Rev Med Pharmaco"},{"key":"B49","article-title":"Effects of Helicobacter Pylori Infection on Self and Anti-HP Antibody Levels in Patients With Autoimmune Thyroid Disease","volume":"20","author":"Zheng","year":"2020","journal-title":"Chin Remedies Clinics"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2004.02137.x","article-title":"Decrease in Thyroid Autoantibodies After Eradication of Helicobacter Pylori Infection","volume":"61","author":"Giovanni","year":"2004","journal-title":"Clin Endocrinol"},{"key":"B51","article-title":"The Association of Helicobacter Pylori Infection With Hashimoto's Thyroiditis","volume":"51","author":"Aghili","year":"2013","journal-title":"Acta Med Iranica"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.33549\/physiolres.933118","article-title":"Activation of Helicobacter Pylori Causes Either Autoimmune Thyroid Diseases or Carcinogenesis in the Digestive Tract","volume":"64","author":"Astl","year":"2015","journal-title":"Physiol Res"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.2014.36","article-title":"Association Between Thyroid Autoimmunity and Helicobacter Pylori Infection","volume":"32","author":"Mi","year":"2017","journal-title":"Korean J Internal Med"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.22929","article-title":"Meta-Analysis of the Correlation Between Helicobacter Pylori Infection and Autoimmune Thyroid Diseases","volume":"8","author":"Yi","year":"2017","journal-title":"Oncotarget"},{"key":"B55","first-page":"48","article-title":"Infection by CagA Positive Strains of Helicobacter Pylori is Associated With Autoimmune Thyroid Disease in Iranian Patients","volume":"9","author":"Mahmood","year":"2012","journal-title":"Iranian J Immunol: IJI"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i10.1093","article-title":"Autoimmune Thyroid Diseases and Helicobacter Pylori: The Correlation is Present Only in Graves\u2019s Disease","volume":"18","author":"Bassi","year":"2012","journal-title":"World J Gastroentero"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1111\/j.1083-4389.2004.00241.x","article-title":"Helicobacter Pylori Infection in Women With Hashimoto Thyroiditis: A Case-Control Study","volume":"95","author":"Haim","year":"2016","journal-title":"MEDICINE"},{"key":"B58","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1083-4389.2004.00241.x","article-title":"Helicobacter Pylori Infection in Patients With Hashimoto\u2019s Thyroiditis","volume":"9","author":"Francesco","year":"2004","journal-title":"Helicobacter"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.1974","article-title":"Maternal Virus Infections in Pregnancy and Type 1 Diabetes in Their Offspring: Systematic Review and Meta-Analysis of Observational Studies","volume":"28","author":"Allen","year":"2018","journal-title":"Rev Med Virol"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7410801","article-title":"Helicobacter Pyloricorrelation Between Infection and Metabolic Abnormality in General Population: A Cross-Sectional Study","volume":"2018","author":"Lu","year":"2018","journal-title":"Gastroent Res Pract"},{"key":"B61","article-title":"The Significance of Campylobacter Pylori Infection in Gastroenterologic and Diabetic Practice","volume":"130","author":"Simon","year":"1989","journal-title":"Orv Hetil"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1097\/01.EPX.0000437621.23560.de","article-title":"The Association Between Helicobacter Pylori Infection, Type 1 Diabetes Mellitus, and Autoimmune Thyroiditis","volume":"88","author":"Zekry","year":"2013","journal-title":"J Egypt Public Health Assoc"},{"key":"B63","first-page":"68","article-title":"Helicobacter Pylori Infection in Children With Type 1 Diabetes Mellitus: A Case-Control Study","volume":"16","author":"Bazmamoun","year":"2016","journal-title":"J Res Health Sci"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1358\/dof.2012.37.10.1886765","article-title":"High Reinfection Rate of Helicobacter Pylori in Young Type 1 Diabetic Patients: A Three-Year Follow-Up Study","volume":"16","author":"Candelli","year":"2012","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"B65","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1080\/09751270.2009.11885133","article-title":"Helicobacter Pylori Infection and Inflammation: Implication for the Pathophysiology of Diabetes and Coronary Heart Disease in Asian Indians","volume":"1","author":"Rahman","year":"2009","journal-title":"J Life Sci"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/3705264","article-title":"The Association Between Helicobacter Pylori Infection and Glycated Hemoglobin A in Diabetes: A Meta-Analysis","volume":"2019","author":"Chen","year":"2019","journal-title":"J Diabetes Res"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1007\/s40200-020-00497-1","article-title":"Helicobacter Pylori Infection and Type 1 Diabetes Mellitus in Children","volume":"19","author":"Esmaeili","year":"2020","journal-title":"J Diabetes Metab Disord"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i17.5407","article-title":"Is Helicobacter Pylori Infection Associated With Glycemic Control in Diabetics","volume":"21","author":"Dai","year":"2015","journal-title":"World J Gastroenterol"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5715403","article-title":"Helicobacter Pylori Infection Is Associated With Type 2 Diabetes, Not Type 1 Diabetes: An Updated Meta-Analysis","volume":"2017","author":"Li","year":"2017","journal-title":"Gastroenterol Res Pract"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i16.4607","article-title":"Helicobacter Pylori Infection and Diabetes: Is it a Myth or Fact","volume":"20","author":"He","year":"2014","journal-title":"World J Gastroenterol"},{"key":"B71","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1111\/jdi.13102","article-title":"Helicobacter Pylori Infection is Associated With Diabetes Among Chinese Adults","volume":"11","author":"Wan","year":"2020","journal-title":"J Diabetes Investig"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.23736\/S0391-1977.19.03021-9","article-title":"Helicobacter Pylori and Diabetes Mellitus: A Controversial Relationship","volume":"44","author":"Valenzano","year":"2019","journal-title":"Minerva Endocrinol"},{"key":"B73","doi-asserted-by":"publisher","first-page":"1989","DOI":"10.1136\/gutjnl-2020-322362","article-title":"Recent Advances in Clinical Practice: Epidemiology of Autoimmune Liver Diseases","volume":"70","author":"Trivedi","year":"2021","journal-title":"GUT"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-008-0522-5","article-title":"Detection of Helicobacter Pylori in Paraffin-Embedded Specimens From Patients With Chronic Liver Diseases, Using the Amplification Method","volume":"54","author":"Pirouz","year":"2009","journal-title":"Dig Dis Sci"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e3283590c10","article-title":"Association Between Helicobacter Pylori and Liver-to-Spleen Ratio: A Randomized-Controlled Single-Blind Study","volume":"25","author":"Do\u011fan","year":"2013","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12138","article-title":"Helicobacter Pylori Dwelling on the Apical Surface of Gastrointestinal Epithelium Damages the Mucosal Barrier Through Direct Contact","volume":"19","author":"Zhang","year":"2014","journal-title":"Helicobacter"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1159\/000051918","article-title":"Helicobacter Pylori Infection Increases Mucosal Permeability of the Stomach and Intestine","volume":"63","author":"Fukuda","year":"2001","journal-title":"DIGESTION"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2009.90","article-title":"Helicobacter Pylori Promotes Hepatic Fibrosis in the Animal Model","volume":"89","author":"Goo","year":"2009","journal-title":"Lab Invest"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2009.02719.x","article-title":"The Pathological Effect of Helicobacter Pylori Infection on Liver Tissues in Mice","volume":"15","author":"Huang","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2013.243","article-title":"Clinical Effects of Helicobacter Pylori Outside the Stomach","volume":"11","author":"Franceschi","year":"2014","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v7.i30.2968","article-title":"Extragastric Manifestations of Helicobacter Pylori Infection: Possible Role of Bacterium in Liver and Pancreas Diseases","volume":"7","author":"Rabelo-Gon\u00e7alves","year":"2015","journal-title":"World J Hepatol"},{"key":"B82","doi-asserted-by":"publisher","first-page":"131","DOI":"10.4103\/2277-9175.133256","article-title":"The Effect of Helicobacter Pylori Eradication on Liver Enzymes in Patients Referring With Unexplained Hypertransaminasemia","volume":"3","author":"Salehi","year":"2014","journal-title":"Adv BioMed Res"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000000928","article-title":"Helicobacter Pylori Infection Among Patients With Liver Cirrhosis","volume":"29","author":"Pogorzelska","year":"2017","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000000220","article-title":"Association Between Cirrhosis and Helicobacter Pylori Infection: A Meta-Analysis","volume":"26","author":"Feng","year":"2014","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.05344-0","article-title":"Increased Prevalence of Seropositivity for Non-Gastric Helicobacter Species in Patients With Autoimmune Liver Disease","volume":"52","author":"Nilsson","year":"2003","journal-title":"J Med Microbiol"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2019.102328","article-title":"The Challenges of Primary Biliary Cholangitis: What is New and What Needs to be Done","volume":"105","author":"Terziroli Beretta-Piccoli","year":"2019","journal-title":"J Autoimmun"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-019-08772-7","article-title":"Clinical Management of Primary Biliary Cholangitis-Strategies and Evolving Trends","volume":"59","author":"Gao","year":"2020","journal-title":"Clin Rev Allerg Immu"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0b013e3282f5e9db","article-title":"Primary Biliary Cirrhosis, Similar to That in Human Beings, in a Male C57BL\/6 Mouse Infected With Helicobacter Pylori","volume":"20","author":"Goo","year":"2008","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1177\/039463201002300431","article-title":"Celiac Disease, Primary Biliary Cirrhosis and Helicobacter Pylori Infection: One Link for Three Diseases","volume":"23","author":"Abenavoli","year":"2010","journal-title":"Int J Immunopath PH"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.3.1072-1076.2000","article-title":"Identification of Helicobacter Pylori and Other Helicobacter Species by PCR, Hybridization, and Partial DNA Sequencing in Human Liver Samples From Patients With Primary Sclerosing Cholangitis or Primary Biliary Cirrhosis","volume":"38","author":"Nilsson","year":"2000","journal-title":"J Clin Microbiol"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2012.09.012","article-title":"Serum Markers of Infections in Patients With Primary Biliary Cirrhosis: Evidence of Infection Burden","volume":"93","author":"Shapira","year":"2012","journal-title":"Exp Mol Pathol"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v7.i18.2136","article-title":"From the Stomach to Other Organs: Helicobacter Pylori and the Liver","volume":"7","author":"Waluga","year":"2015","journal-title":"World J Hepatol"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-008-8087-9","article-title":"Bacteria and Primary Biliary Cirrhosis","volume":"36","author":"Bogdanos","year":"2009","journal-title":"Clin Rev Allergy Immunol"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-018-1484-9","article-title":"Clinical Guidelines for Primary Sclerosing Cholangitis 2017","volume":"53","author":"Isayama","year":"2018","journal-title":"J Gastroenterol"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.12865\/chsj.44.02.16","article-title":"The Association Between Helicobacter Pylori Infection and Liver and Biliary Tract Disorders","volume":"44","author":"Popescu","year":"2018","journal-title":"Curr Health Sci J"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-007-9803-7","article-title":"Helicobacter Pylori may Play a Contributory Role in the Pathogenesis of Primary Sclerosing Cholangitis","volume":"52","author":"Krasinskas","year":"2007","journal-title":"Dig Dis Sci"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.3109\/00365520903426915","article-title":"Helicobacter Species DNA in Liver and Gastric Tissues in Children and Adolescents With Chronic Liver Disease","volume":"45","author":"Casswall","year":"2010","journal-title":"Scand J Gastroenterol"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-020117-043534","article-title":"Cellular and Molecular Mechanisms of Autoimmune Hepatitis","volume":"13","author":"Webb","year":"2018","journal-title":"Annu Rev Pathol"},{"key":"B99","doi-asserted-by":"publisher","first-page":"18017","DOI":"10.1038\/nrdp.2018.17","article-title":"Autoimmune Hepatitis","volume":"4","author":"Mieli-Vergani","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-313332","article-title":"Gut Microbial Profile is Altered in Primary Biliary Cholangitis and Partially Restored After UDCA Therapy","volume":"67","author":"Tang","year":"2018","journal-title":"GUT"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2018.05.002","article-title":"Liver-Microbiome Axis in Health and Disease","volume":"39","author":"Adolph","year":"2018","journal-title":"Trends Immunol"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-310500","article-title":"The Gut Microbial Profile in Patients With Primary Sclerosing Cholangitis is Distinct From Patients With Ulcerative Colitis Without Biliary Disease and Healthy Controls","volume":"66","author":"Kummen","year":"2017","journal-title":"GUT"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-317836","article-title":"Alterations of Gut Microbiome in Autoimmune Hepatitis","volume":"69","author":"Wei","year":"2020","journal-title":"GUT"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1007\/s40200-020-00608-y","article-title":"The Impact of Helicobacter Pylori Infection on Gut Microbiota-Endocrine System Axis; Modulation of Metabolic Hormone Levels and Energy Homeostasis","volume":"19","author":"Mohammadi","year":"2020","journal-title":"J Diabetes Metab Disord"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i3.613","article-title":"Helicobacter Pylori and Autoimmune Disease: Cause or Bystander","volume":"20","author":"Smyk","year":"2014","journal-title":"World J Gastroentero"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1023\/A:1013782408510","article-title":"Helicobacter Pylori Seroprevalence in Patients With Autoimmune Hepatitis","volume":"47","author":"Durazzo","year":"2002","journal-title":"Dig Dis Sci"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204627","article-title":"The Global Burden of Rheumatoid Arthritis: Estimates From the Global Burden of Disease 2010 Study","volume":"73","author":"Cross","year":"2014","journal-title":"Ann Rheum Dis"},{"key":"B108","doi-asserted-by":"publisher","first-page":"18001","DOI":"10.1038\/nrdp.2018.1","article-title":"Rheumatoid Arthritis","volume":"4","author":"Smolen","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2020.102735","article-title":"Beyond the Joints, the Extra-Articular Manifestations in Rheumatoid Arthritis","volume":"20","author":"Conforti","year":"2021","journal-title":"Autoimmun Rev"},{"key":"B110","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.imlet.2019.05.014","article-title":"Relationship Between Helicobacter Pylori Cytotoxin-Associated Gene A Protein With Clinical Outcomes in Patients With Rheumatoid Arthritis","volume":"211","author":"Ebrahimi","year":"2019","journal-title":"Immunol Lett"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2002.01284.x","article-title":"Eradication of Helicobacter Pylori may Reduce Disease Severity in Rheumatoid Arthritis","volume":"16","author":"Zentilin","year":"2002","journal-title":"Aliment Pharmacol Ther"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2011.01796.x","article-title":"Helicobacter Pylori and Autoimmune Diseases","volume":"17","author":"Hasni","year":"2011","journal-title":"Oral Dis"},{"key":"B113","article-title":"Impact on Level of Serum IL-8 and IL-18 by Helicobacter Pylori Eradication Ther- Apy in Patients With Rheumatoid Arthritis","volume":"31","author":"Liu","year":"2015","journal-title":"Chin J Immunol"},{"key":"B114","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1080\/03009742.2018.1464205","article-title":"Helicobacter Pylori Infection is Not Associated With Rheumatoid Arthritis","volume":"48","author":"Bartels","year":"2019","journal-title":"Scand J Rheumatol"},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-009-8158-6","article-title":"Infectious Aspects and the Etiopathogenesis of Rheumatoid Arthritis","volume":"38","author":"Meron","year":"2010","journal-title":"Clin Rev Allergy Immunol"},{"key":"B116","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-005-0419-5","article-title":"Prevalence of Helicobacter Pylori Infection and Risk of Upper Gastrointestinal Ulcer in Patients With Rheumatoid Arthritis in Japan","volume":"15","author":"Tanaka","year":"2005","journal-title":"Mod Rheumatol"},{"key":"B117","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2020.08.011","article-title":"Helicobacter Pylori Infection and Autoimmune Diseases; Is There an Association With Systemic Lupus Erythematosus, Rheumatoid Arthritis, Autoimmune Atrophy Gastritis and Autoimmune Pancreatitis? A Systematic Review and Meta-Analysis Study","volume":"54","author":"Youssefi","year":"2021","journal-title":"J Microbiol Immunol Infect"},{"key":"B118","doi-asserted-by":"publisher","first-page":"284","DOI":"10.3934\/microbiol.2021018","article-title":"Helicobacter Pylori Induced Immune Thrombocytopenic Purpura and Perspective Role of Helicobacter Pylori Eradication Therapy for Treating Immune Thrombocytopenic Purpura","volume":"7","author":"Ihtesham","year":"2021","journal-title":"Aims Microbiol"},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.5009\/gnl14483","article-title":"The Effects of Helicobacter Pylori Eradication Therapy for Chronic IdiopathicThrombocytopenic Purpura","volume":"10","author":"Hwang","year":"2016","journal-title":"Gut Liver"},{"key":"B120","doi-asserted-by":"publisher","first-page":"9370","DOI":"10.1038\/s41598-020-66460-5","article-title":"Helicobacter Pylori Eradication Affects Platelet Count Recovery in Immune Thrombocytopenia","volume":"10","author":"Lee","year":"2020","journal-title":"Sci Rep"},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.3109\/09537104.2014.911836","article-title":"Helicobacter Pylori Infection & Immune Thrombocytopenic Purpura in Children and Adolescents: A Randomized Controlled Trial","volume":"26","author":"Brito","year":"2015","journal-title":"Platelets"},{"key":"B122","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.3390\/microorganisms8101457","article-title":"Efficacy of Helicobacter Pylori Eradication Therapy on Platelet Recovery in Pediatric Immune Thrombocytopenic Purpura-Case Series and a Systematic Review","volume":"8","author":"Ikuse","year":"2020","journal-title":"Microorganisms"},{"key":"B123","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13341","article-title":"Effectiveness of Helicobacter Pylori Eradication in Pregnant Women With Idiopathic Thrombocytopenic Purpura","volume":"43","author":"Ono","year":"2017","journal-title":"J Obstet Gynaecol Res"},{"key":"B124","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9529752","article-title":"Role of Helicobacter Pylori Eradication Therapy on Platelet Recovery in Chronic Immune Thrombocytopenic Purpura","volume":"2017","author":"Sheema","year":"2017","journal-title":"Gastroenterol Res Pract"},{"key":"B125","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1186\/s12878-018-0119-y","article-title":"The Impact of Helicobacter Pylori Eradication on Platelet Counts of Adult Patients With Idiopathic Thrombocytopenic Purpura","volume":"18","author":"Aljarad","year":"2018","journal-title":"BMC Hematol"},{"key":"B126","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.5551","article-title":"Helicobacter Pylori: An Underrated Cause of Immune Thrombocytopenic Purpura. A Comprehensive Review","volume":"11","author":"Zain","year":"2019","journal-title":"Cureus"},{"key":"B127","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s12016-020-08817-2","article-title":"Management of Severe Refractory Systemic Lupus Erythematosus: Real-World Experience and Literature Review","volume":"60","author":"Yang","year":"2021","journal-title":"Clin Rev Allerg Immu"},{"key":"B128","article-title":"Research Advances in Systemic Lupus Erythematosus in 2020","volume":"54","author":"Luo","year":"2021","journal-title":"Chin J Dermatol"},{"key":"B129","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i36.12839","article-title":"Role of Helicobacter Pylori Infection in Autoimmune Systemic Rheumatic Diseases","volume":"20","author":"Radi\u0107","year":"2014","journal-title":"World J Gastroenterol"},{"key":"B130","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2019.00330","article-title":"Increased Risk of Systemic Lupus Erythematosus in Patients With Helicobacter Pylori Infection: A Nationwide Population-Based Cohort Study","volume":"6","author":"Wu","year":"2019","journal-title":"Front Med (Lausanne)"},{"key":"B131","doi-asserted-by":"publisher","DOI":"10.1177\/0961203320923393","article-title":"Effect of Early Eradication Therapy on Systemic Lupus Erythematosus Risk in Patients With Helicobacter Pylori Infection: A Nationwide Population-Based Cohort Study","volume":"29","author":"Wu","year":"2020","journal-title":"Lupus"},{"key":"B132","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-019-04805-w","article-title":"Helicobacter Pylori Infection and Gastroduodenal Lesions in Patients With Systemic Lupus Erythematosus","volume":"39","author":"Mendoza-Pinto","year":"2020","journal-title":"Clin Rheumatol"},{"key":"B133","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01488","article-title":"Helicobacter Pylori Infection Increased Anti-dsDNA and Enhanced Lupus Severity in Symptomatic Fc\u03b3riib-Deficient Lupus Mice","volume":"9","author":"Saowapha","year":"2018","journal-title":"Front Microbiol"},{"key":"B134","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000490","article-title":"Infections: A Double-Edge Sword in Autoimmunity","volume":"30","author":"Shamriz","year":"2018","journal-title":"Curr Opin Rheumatol"},{"key":"B135","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12916-015-0306-7","article-title":"Unraveling the Hygiene Hypothesis of Helminthes and Autoimmunity: Origins, Pathophysiology, and Clinical Applications","volume":"13","author":"Versini","year":"2015","journal-title":"BMC Med"},{"key":"B136","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.109122","article-title":"Current Mechanistic Insights Into the Role of Infection in Systemic Lupus Erythematosus","volume":"117","author":"Pan","year":"2019","journal-title":"BioMed Pharmacother"},{"key":"B137","article-title":"Association Between Systemic Lupus Erythematosus and Helicobacter Pylori Seronegativity","volume":"31","author":"Sawalha","year":"2004","journal-title":"J Rheumatol"},{"key":"B138","doi-asserted-by":"publisher","first-page":"191","DOI":"10.7150\/ijms.17718","article-title":"Reviewing Primary Sj\u00f6gren\u2019s Syndrome: Beyond the Dryness - From Pathophysiology to Diagnosis and Treatment","volume":"14","author":"Tim","year":"2017","journal-title":"Int J Med Sci"},{"key":"B139","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/j.clim.2017.04.005","article-title":"Sjogren\u2019s Syndrome: Clinical Aspects","volume":"182","author":"Vivino","year":"2017","journal-title":"Clin Immunol"},{"key":"B140","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2006.08.002","article-title":"Pathophysiology of Sj\u00f6gren\u2019s Syndrome","volume":"37","author":"Garc\u00eda-Carrasco","year":"2006","journal-title":"Arch Med Res"},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2017.09.010","article-title":"Gastrointestinal and Hepatic Disease in Sjogren Syndrome","volume":"44","author":"Popov","year":"2018","journal-title":"Rheum Dis Clin N Am"},{"key":"B142","doi-asserted-by":"publisher","DOI":"10.2174\/1573397114666181113102427","article-title":"Helicobacter Pylori Infection in Sj\u00f6gren\u2019s Syndrome: Co-Incidence or Causality","volume":"15","author":"Massoud","year":"2019","journal-title":"Curr Rheumatol Rev"},{"key":"B143","doi-asserted-by":"publisher","DOI":"10.1097\/md.0000000000013528","article-title":"Association Between Helicobacter Pylori Infection and Sj\u00f6gren Syndrome: A Meta-Analysis","volume":"97","author":"Qianqian","year":"2018","journal-title":"Medicine"},{"key":"B144","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2004.04.005","article-title":"Sjogren\u2019s Syndrome: Concomitant H. Pylori Infection and Possible Correlation With Clinical Parameters","volume":"72","author":"EMY","year":"2005","journal-title":"Joint Bone Spine"},{"key":"B145","doi-asserted-by":"publisher","DOI":"10.1002\/art.10746","article-title":"Salivary Gland Lymphocytic Infiltrates and Helicobacter Pylori Serology in Anti-SSA\/Ro Positive Patients in Italy","volume":"21","author":"Capolari","year":"2003","journal-title":"Clin Exp Rheumatol"},{"key":"B146","article-title":"Presence of Antibodies Against Helicobacter Pylori and its Heat-Shock Protein 60 in the Serum of Patients With Sj\u00f6gren\u2019s Syndrome","volume":"26","author":"Aragona","year":"1999","journal-title":"J Rheumatol"},{"key":"B147","article-title":"Lack of Correlation Between Gastric Helicobacter Pylori Infection and Primary or Secondary Raynaud\u2019s Phenomenon in Patients With Systemic Sclerosis","volume":"27","author":"Sulli","year":"2000","journal-title":"J Rheumatol"},{"key":"B148","doi-asserted-by":"publisher","first-page":"27","DOI":"10.2174\/1872213X13666190328164931","article-title":"Chronic Urticaria: An Overview of Treatment and Recent Patents","volume":"13","author":"Hon","year":"2019","journal-title":"Recent Pat Inflamm Allergy Drug Discovery"},{"key":"B149","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.iac.2013.09.012","article-title":"Chronic Spontaneous Urticaria: Etiology and Pathogenesis","volume":"34","author":"Saini","year":"2014","journal-title":"Immunol Allergy Clin North Am"},{"key":"B150","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/5932038","article-title":"Association Between Chronic Urticaria and Helicobacter Pylori Infection Among Patients Attending a Tertiary Hospital in Tanzania","volume":"2020","author":"Dennis","year":"2020","journal-title":"Dermatol Res Pract"},{"key":"B151","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/486974","article-title":"Association Between Helicobacter Pylori Infection and Chronic Urticaria: A Meta-Analysis","volume":"2015","author":"Gu","year":"2015","journal-title":"Gastroenterol Res Pract"},{"key":"B152","doi-asserted-by":"publisher","DOI":"10.21037\/apm-21-2324","article-title":"A Systematic Review and Meta-Analysis of the Correlation Between Helicobacter Pylori Infection and Chronic Urticaria","volume":"10","author":"Cui","year":"2021","journal-title":"Ann Palliat Med"},{"key":"B153","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/01.NPR.0000471366.32982.f2","article-title":"Helicobacter Pylori: A Significant and Treatable Cause of Chronic Urticaria and Angioedema","volume":"40","author":"Rasooly","year":"2015","journal-title":"Nurse Pract"},{"key":"B154","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2007.00522.x","article-title":"Eradication of Helicobacter Pylori Infection Equally Improves Chronic Urticaria With Positive and Negative Autologous Serum Skin Test","volume":"12","author":"Magen","year":"2007","journal-title":"Helicobacter"},{"key":"B155","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12661","article-title":"Systematic Review and Meta-Analysis: Effect of Helicobacter Pylori Eradication on Chronic Spontaneous Urticaria","volume":"24","author":"Kim","year":"2019","journal-title":"Helicobacter"},{"key":"B156","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-5378.2008.00620.x","article-title":"Role of Helicobacter Pylori Infection in the Treatment and Outcome of Chronic Urticaria","volume":"13","author":"Hellmig","year":"2008","journal-title":"Helicobacter"},{"key":"B157","first-page":"97","article-title":"Current Developments in the Immunology of Psoriasis","volume":"93","author":"Gr\u00e4n","year":"2020","journal-title":"Yale J Biol Med"},{"key":"B158","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000020632","article-title":"Relationship Between Helicobacter Pylori Infection and Psoriasis: A Nationwide Population-Based Longitudinal Cohort Study","volume":"99","author":"Wu","year":"2020","journal-title":"Med (Baltimore)"},{"key":"B159","doi-asserted-by":"publisher","DOI":"10.5144\/0256-4947.2014.241","article-title":"Relationship Between Helicobacter Pylori Infection and Psoriasis","volume":"34","author":"Azizzadeh","year":"2014","journal-title":"Ann Saudi Med"},{"key":"B160","doi-asserted-by":"publisher","first-page":"645","DOI":"10.3390\/medicina55100645","article-title":"Helicobacter Pylori Infection and Psoriasis: A Systematic Review and Meta-Analysis","volume":"55","author":"Yu","year":"2019","journal-title":"Med (Kaunas)"},{"key":"B161","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.12798","article-title":"Helicobacter Pylori Infection in Psoriasis: Results of a Clinical Study and Review of the Literature","volume":"54","author":"Campanati","year":"2015","journal-title":"Int J Dermatol"},{"key":"B162","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2011.1579","article-title":"Impact of Helicobacter Pylori Infection on Severity of Psoriasis and Response to Treatment","volume":"22","author":"Onsun","year":"2012","journal-title":"Eur J Dermatol"},{"key":"B163","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2011.10.022","article-title":"Genes, Epigenetic Regulation and Environmental Factors: Which is the Most Relevant in Developing Autoimmune Diseases","volume":"11","author":"Costenbader","year":"2012","journal-title":"Autoimmun Rev"},{"key":"B164","article-title":"Helicobacter Pylori CagA Antibodies and Thyroid Function in Latent Autoimmune Diabetes in Adults","volume":"20","author":"Delitala","year":"2016","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"B165","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3390\/antibiotics9010012","article-title":"Helicobacter Pylori Infection and Autoimmune Thyroid Diseases: The Role of Virulent Strains","volume":"9","author":"Figura","year":"2019","journal-title":"Antibiot (Basel)"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2022.833424\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,10]],"date-time":"2022-02-10T07:35:08Z","timestamp":1644478508000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2022.833424\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,10]]},"references-count":165,"alternative-id":["10.3389\/fimmu.2022.833424"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2022.833424","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,10]]},"article-number":"833424"}}