{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T18:20:42Z","timestamp":1791656442180,"version":"4.3.4"},"reference-count":76,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:00:00Z","timestamp":1723420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"abstract":"<jats:p>\n                    Endometriosis is a chronic inflammatory disease that causes debilitating pelvic pain in women. Macrophages are considered to be key players in promoting disease progression, as abundant macrophages are present in ectopic lesions and elevated in the peritoneum. In the present study, we examined the role of GATA6\n                    <jats:sup>+<\/jats:sup>\n                    peritoneal macrophages on endometriosis-associated hyperalgesia using mice with a specific myeloid deficiency of GATA6. Lesion induction induced the disappearance of TIM4\n                    <jats:sup>hi<\/jats:sup>\n                    MHCII\n                    <jats:sup>lo<\/jats:sup>\n                    residential macrophages and the influx of increased Ly6C\n                    <jats:sup>+<\/jats:sup>\n                    monocytes and TIM4\n                    <jats:sup>lo<\/jats:sup>\n                    MHCII\n                    <jats:sup>hi<\/jats:sup>\n                    macrophages. The recruitment of MHCII\n                    <jats:sup>hi<\/jats:sup>\n                    inflammatory macrophages was extensive in Mac\n                    <jats:italic>\n                      <jats:sup>Gata6<\/jats:sup>\n                    <\/jats:italic>\n                    KO mice due to the severe disappearance of TIM4\n                    <jats:sup>hi<\/jats:sup>\n                    MHCII\n                    <jats:sup>lo<\/jats:sup>\n                    residential macrophages. Ki67 expression confirmed GATA6-dependent proliferative ability, showing different proliferative phenotypes of TIM4\n                    <jats:sup>+<\/jats:sup>\n                    residential macrophages in\n                    <jats:italic>\n                      Gata6\n                      <jats:sup>f\/f<\/jats:sup>\n                    <\/jats:italic>\n                    and Mac\n                    <jats:italic>\n                      <jats:sup>Gata6<\/jats:sup>\n                    <\/jats:italic>\n                    KO mice. Peritoneal proinflammatory cytokines were elevated after lesion induction. When cytokine levels were compared between\n                    <jats:italic>\n                      Gata6\n                      <jats:sup>f\/f<\/jats:sup>\n                    <\/jats:italic>\n                    and Mac\n                    <jats:italic>\n                      <jats:sup>Gata6<\/jats:sup>\n                    <\/jats:italic>\n                    KO mice, TNF\u03b1 at day 21 in\n                    <jats:italic>\n                      Gata6\n                      <jats:sup>f\/f<\/jats:sup>\n                    <\/jats:italic>\n                    mice was higher than in Mac\n                    <jats:italic>\n                      <jats:sup>Gata6<\/jats:sup>\n                    <\/jats:italic>\n                    KO mice. Lesion induction increased both abdominal and hind paw sensitivities.\n                    <jats:italic>\n                      Gata6\n                      <jats:sup>f\/f<\/jats:sup>\n                    <\/jats:italic>\n                    mice tended to show higher sensitivity in the abdomen after day 21. Elevated expression of TRPV1 and CGRP was observed in the dorsal root ganglia after ELL induction in\n                    <jats:italic>\n                      Gata6\n                      <jats:sup>f\/f<\/jats:sup>\n                    <\/jats:italic>\n                    mice until days 21 and 42, respectively. These results support that peritoneal GATA6\n                    <jats:sup>+<\/jats:sup>\n                    macrophages are involved in the recruitment and reprogramming of monocyte-derived macrophages. The extensive recruitment of monocyte-derived macrophages in Mac\n                    <jats:italic>\n                      <jats:sup>Gata6<\/jats:sup>\n                    <\/jats:italic>\n                    KO mice might protect against inflammatory stimuli during the resolution phase, whereas GATA6 deficiency did not affect lesion initiation and establishment at the acute phase of inflammation. GATA6\n                    <jats:sup>+<\/jats:sup>\n                    residential macrophages act to sustain local inflammation in the peritoneum and sensitivities in the neurons, reflecting endometriosis-associated hyperalgesia.\n                  <\/jats:p>","DOI":"10.3389\/fimmu.2024.1396000","type":"journal-article","created":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:31:17Z","timestamp":1723422677000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["The involvement of peritoneal GATA6+ macrophages in the pathogenesis of endometriosis"],"prefix":"10.3389","volume":"15","author":[{"given":"Mingxin","family":"Shi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"II","given":"James A.","family":"MacLean","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanako","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,8,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.04.041","article-title":"Endometriosis: etiology, pathobiology, and therapeutic prospects","volume":"184","author":"Saunders","year":"2021","journal-title":"Cell"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1810764","article-title":"Endometriosis","volume":"382","author":"Zondervan","year":"2020","journal-title":"New Engl J Med"},{"key":"B3","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.fertnstert.2011.05.090","article-title":"Impact of endometriosis on quality of life and work productivity: A multicenter study across ten countries","volume":"96","author":"Nnoaham","year":"2011","journal-title":"Fertility Sterility"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2008.09.003","article-title":"Depressive symptoms, anxiety, and quality of life in women with pelvic endometriosis","volume":"142","author":"Sepulcri Rde","year":"2009","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des073","article-title":"The burden of endometriosis: costs and quality of life of women with endometriosis and treated in referral centres","volume":"27","author":"Simoens","year":"2012","journal-title":"Hum Reprod"},{"key":"B6","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/s41572-018-0008-5","article-title":"Endometriosis","volume":"4","author":"Zondervan","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)81391-X","article-title":"Revised american society for reproductive medicine classification of endometriosis: 1996","volume":"67","year":"1997","journal-title":"Fertility Sterility"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del339","article-title":"Association between endometriosis stage, lesion type, patient characteristics and severity of pelvic pain symptoms: A multivariate analysis of over 1000 patients","volume":"22","author":"Vercellini","year":"2007","journal-title":"Hum Reprod"},{"key":"B9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1530\/RAF-20-0072","article-title":"Pelvic pain correlates with peritoneal macrophage abundance not endometriosis","volume":"2","author":"Gibson","year":"2021","journal-title":"Reprod Fertil"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dew293","article-title":"World endometriosis society consensus on the classification of endometriosis","volume":"32","author":"Johnson","year":"2017","journal-title":"Hum Reprod"},{"key":"B11","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1034\/j.1600-0897.2003.00042.x","article-title":"Immunology and endometriosis","volume":"50","author":"Berkkanoglu","year":"2003","journal-title":"Am J Reprod Immunol"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2011.07.029","article-title":"Proangiogenic tie2(+) macrophages infiltrate human and murine endometriotic lesions and dictate their growth in a mouse model of the disease","volume":"179","author":"Capobianco","year":"2011","journal-title":"Am J Pathol"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)58262-4","article-title":"Basal and stimulated secretion of cytokines by peritoneal macrophages in women with endometriosis","volume":"65","author":"Rana","year":"1996","journal-title":"Fertility Sterility"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.00007","article-title":"Endometriosis-associated macrophages: origin, phenotype, and function","volume":"11","author":"Hogg","year":"2020","journal-title":"Front Endocrinol (Lausanne)"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2013776118","article-title":"Macrophages inhibit and enhance endometriosis depending on their origin","volume":"118","author":"Hogg","year":"2021","journal-title":"Proc Natl Acad Sci U.S.A"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2018.07.004","article-title":"The immunopathophysiology of endometriosis","volume":"24","author":"Symons","year":"2018","journal-title":"Trends Mol Med"},{"key":"B17","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1095\/biolreprod.116.140236","article-title":"Niclosamide as a potential nonsteroidal therapy for endometriosis that preserves reproductive function in an experimental mouse model","volume":"95","author":"Prather","year":"2016","journal-title":"Biol Reprod"},{"key":"B18","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1093\/biolre\/ioy222","article-title":"Endometriotic inflammatory microenvironment induced by macrophages can be targeted by niclosamidedagger","volume":"100","author":"Sekulovski","year":"2019","journal-title":"Biol Reprod"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1093\/biolre\/ioaa010","article-title":"Niclosamide suppresses macrophage induced inflammation in endometriosis","volume":"102","author":"Sekulovski","year":"2020","journal-title":"Biol Reprod"},{"key":"B20","doi-asserted-by":"publisher","first-page":"e21584","DOI":"10.1096\/fj.202002541RRR","article-title":"Efficacy of niclosamide on the intra-abdominal inflammatory environment in endometriosis","volume":"35","author":"Shi","year":"2021","journal-title":"FASEB J"},{"key":"B21","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1038\/s42003-022-04211-0","article-title":"Niclosamide targets the dynamic progression of macrophages for the resolution of endometriosis in a mouse model","volume":"5","author":"Zhao","year":"2022","journal-title":"Commun Biol"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2013.00009","article-title":"Endometriosis, a disease of the macrophage","volume":"4","author":"Capobianco","year":"2013","journal-title":"Front Immunol"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)60062-6","article-title":"Characterization of leukocyte subpopulations in the peritoneal fluid of women with endometriosis","volume":"50","author":"Hill","year":"1988","journal-title":"Fertility Sterility"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2009.081011","article-title":"Macrophages are alternatively activated in patients with endometriosis and required for growth and vascularization of lesions in a mouse model of disease","volume":"175","author":"Bacci","year":"2009","journal-title":"Am J Pathol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"222ra16","DOI":"10.1126\/scitranslmed.3007988","article-title":"Molecular network analysis of endometriosis reveals a role for C-jun-regulated macrophage activation","volume":"6","author":"Beste","year":"2014","journal-title":"Sci Trans Med"},{"key":"B26","doi-asserted-by":"publisher","first-page":"fj201900797R","DOI":"10.1096\/fj.201900797R","article-title":"Macrophage-derived insulin-like growth factor-1 is a key neurotrophic and nerve-sensitizing factor in pain associated with endometriosis","volume":"33","author":"Forster","year":"2019","journal-title":"FASEB J"},{"key":"B27","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1186\/s12974-017-0828-3","article-title":"Macrophage and nerve interaction in endometriosis","volume":"14","author":"Wu","year":"2017","journal-title":"J Neuroinflamm"},{"key":"B28","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1093\/humrep\/17.1.69","article-title":"Il-1, il-6 and tnf-alpha concentrations in the peritoneal fluid of women with pelvic adhesions","volume":"17","author":"Cheong","year":"2002","journal-title":"Hum Reprod"},{"key":"B29","doi-asserted-by":"publisher","first-page":"7037","DOI":"10.1038\/s41598-019-43185-8","article-title":"Vegf receptor 1-expressing macrophages recruited from bone marrow enhances angiogenesis in endometrial tissues","volume":"9","author":"Sekiguchi","year":"2019","journal-title":"Sci Rep"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/nature12034","article-title":"Macrophage biology in development, homeostasis and disease","volume":"496","author":"Wynn","year":"2013","journal-title":"Nature"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0915000107","article-title":"Two physically, functionally, and developmentally distinct peritoneal macrophage subsets","volume":"107","author":"Ghosn","year":"2010","journal-title":"Proc Natl Acad Sci U.S.A"},{"key":"B32","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.immuni.2012.12.001","article-title":"Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis","volume":"38","author":"Yona","year":"2013","journal-title":"Immunity"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11852","article-title":"Long-lived self-renewing bone marrow-derived macrophages displace embryo-derived cells to inhabit adult serous cavities","volume":"7","author":"Bain","year":"2016","journal-title":"Nat Commun"},{"key":"B34","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1016\/j.cell.2019.08.009","article-title":"Fate mapping via ms4a3-expression history traces monocyte-derived cells","volume":"178","author":"Liu","year":"2019","journal-title":"Cell"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1002\/eji.202048881","article-title":"The expanding world of tissue-resident macrophages","volume":"51","author":"Jenkins","year":"2021","journal-title":"Eur J Immunol"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2012.08.026","article-title":"Ly6c hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells","volume":"37","author":"Zigmond","year":"2012","journal-title":"Immunity"},{"key":"B37","doi-asserted-by":"publisher","first-page":"1770","DOI":"10.1038\/s41467-021-21778-0","article-title":"Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells","volume":"12","author":"Louwe","year":"2021","journal-title":"Nat Commun"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.04.016","article-title":"Tissue-specific signals control reversible program of localization and functional polarization of macrophages","volume":"157","author":"Okabe","year":"2014","journal-title":"Cell"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1126\/science.1251414","article-title":"The transcription factor gata6 links tissue macrophage phenotype and proliferative renewal","volume":"344","author":"Rosas","year":"2014","journal-title":"Science"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20140570","article-title":"Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival","volume":"211","author":"Gautier","year":"2014","journal-title":"J Exp Med"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202206617","article-title":"Mouse tissue-resident peritoneal macrophages in homeostasis, repair, infection, and tumor metastasis","volume":"10","author":"Ardavin","year":"2023","journal-title":"Adv Sci (Weinh)"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2022.12.002","article-title":"Gata6(+) large peritoneal macrophages: an evolutionarily conserved sentinel and effector system for infection and injury","volume":"44","author":"Salm","year":"2023","journal-title":"Trends Immunol"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.03.009","article-title":"A reservoir of mature cavity macrophages that can rapidly invade visceral organs to affect tissue repair","volume":"165","author":"Wang","year":"2016","journal-title":"Cell"},{"key":"B44","doi-asserted-by":"publisher","first-page":"7294","DOI":"10.1038\/s41467-021-27614-9","article-title":"Directly recruited gata6 + Peritoneal cavity macrophages contribute to the repair of intestinal serosal injury","volume":"12","author":"Honda","year":"2021","journal-title":"Nat Commun"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1126\/science.abe0595","article-title":"Primordial gata6 macrophages function as extravascular platelets in sterile injury","volume":"371","author":"Zindel","year":"2021","journal-title":"Science"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1038\/s41467-020-15371-0","article-title":"Rxrs control serous macrophage neonatal expansion and identity and contribute to ovarian cancer progression","volume":"11","author":"Casanova-Acebes","year":"2020","journal-title":"Nat Commun"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-4375","article-title":"Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice","volume":"67","author":"Robinson-Smith","year":"2007","journal-title":"Cancer Res"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-3373","article-title":"Macrophage blockade using csf1r inhibitors reverses the vascular leakage underlying Malignant ascites in late-stage epithelial ovarian cancer","volume":"75","author":"Moughon","year":"2015","journal-title":"Cancer Res"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.141115","article-title":"Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis","volume":"5","author":"Xia","year":"2020","journal-title":"JCI Insight"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.7150\/jca.31787","article-title":"Macrophages on the peritoneum are involved in gastric cancer peritoneal metastasis","volume":"10","author":"Song","year":"2019","journal-title":"J Cancer"},{"key":"B51","doi-asserted-by":"publisher","first-page":"4406","DOI":"10.1038\/s41467-022-32080-y","article-title":"Gata6(+) resident peritoneal macrophages promote the growth of liver metastasis","volume":"13","author":"Hossain","year":"2022","journal-title":"Nat Commun"},{"key":"B52","doi-asserted-by":"publisher","first-page":"12794","DOI":"10.1038\/s41598-018-30787-x","article-title":"Characterization of human peritoneal monocyte\/macrophage subsets in homeostasis: phenotype, gata6, phagocytic\/oxidative activities and cytokines expression","volume":"8","author":"Ruiz-Alcaraz","year":"2018","journal-title":"Sci Rep"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2014.03.011","article-title":"A novel mouse model of endometriosis mimics human phenotype and reveals insights into the inflammatory contribution of shed endometrium","volume":"184","author":"Greaves","year":"2014","journal-title":"Am J Pathol"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0086378","article-title":"Evidence from a mouse model that epithelial cell migration and mesenchymal-epithelial transition contribute to rapid restoration of uterine tissue integrity during menstruation","volume":"9","author":"Cousins","year":"2014","journal-title":"PloS One"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1038\/srep44169","article-title":"Ep2 receptor antagonism reduces peripheral and central hyperalgesia in a preclinical mouse model of endometriosis","volume":"7","author":"Greaves","year":"2017","journal-title":"Sci Rep"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1101\/2023.11.09.566474","article-title":"High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia","volume":"15","author":"Herup-Wheeler","year":"2024","journal-title":"Front Endocrinol (Lausanne)"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-03-562710","article-title":"Resolution of acute inflammation bridges the gap between innate and adaptive immunity","volume":"124","author":"Newson","year":"2014","journal-title":"Blood"},{"key":"B58","doi-asserted-by":"publisher","first-page":"1886","DOI":"10.1038\/ncomms2877","article-title":"Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation","volume":"4","author":"Davies","year":"2013","journal-title":"Nat Commun"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201141817","article-title":"A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation","volume":"41","author":"Davies","year":"2011","journal-title":"Eur J Immunol"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-01-478206","article-title":"Local apoptosis mediates clearance of macrophages from resolving inflammation in mice","volume":"122","author":"Gautier","year":"2013","journal-title":"Blood"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00935","article-title":"Regulation of inflammation pathways and inflammasome by sex steroid hormones in endometriosis","volume":"10","author":"Garcia-Gomez","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"key":"B62","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0015-0282(01)01816-7","article-title":"Role of cytokines in endometriosis","volume":"76","author":"Harada","year":"2001","journal-title":"Fertility Sterility"},{"key":"B63","doi-asserted-by":"publisher","first-page":"54","DOI":"10.3390\/biomedicines9010054","article-title":"Inflammatory mediators and pain in endometriosis: A systematic review","volume":"9","author":"Machairiotis","year":"2021","journal-title":"Biomedicines"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(00)01752-0","article-title":"Interleukin 1beta, interleukin-6, and tumor necrosis factor-alpha in endometriotic tissue and in endometrium","volume":"75","author":"Bergqvist","year":"2001","journal-title":"Fertility Sterility"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.1995.tb00968.x","article-title":"Il-1 beta, tnf-alpha, and il-2 in peritoneal fluid and macrophage-conditioned media of women with endometriosis","volume":"34","author":"Keenan","year":"1995","journal-title":"Am J Reprod Immunol"},{"key":"B66","doi-asserted-by":"publisher","first-page":"96","DOI":"10.5114\/ceji.2015.50840","article-title":"Pro-inflammatory cytokines for evaluation of inflammatory status in endometriosis","volume":"40","author":"Malutan","year":"2015","journal-title":"Cent Eur J Immunol"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.11.200","article-title":"Peritoneal fluid macrophages in endometriosis: correlation between the expression of estrogen receptors and inflammation","volume":"90","author":"Montagna","year":"2008","journal-title":"Fertility Sterility"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2011.08.004","article-title":"Imbalance between sympathetic and sensory innervation in peritoneal endometriosis","volume":"26","author":"Arnold","year":"2012","journal-title":"Brain Behav Immun"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4334","article-title":"Emerging targets in neuroinflammation-driven chronic pain","volume":"13","author":"Ji","year":"2014","journal-title":"Nat Rev Drug Discovery"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1002\/path.2588","article-title":"Downregulation of cd36 results in reduced phagocytic ability of peritoneal macrophages of women with endometriosis","volume":"219","author":"Chuang","year":"2009","journal-title":"J Pathol"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-003-0591-9","article-title":"Tumor necrosis factor alpha secretion by peritoneal macrophages in patients with endometriosis","volume":"271","author":"Richter","year":"2005","journal-title":"Arch Gynecol Obstet"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abc4466","article-title":"Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages","volume":"5","author":"Bain","year":"2020","journal-title":"Sci Immunol"},{"key":"B73","doi-asserted-by":"publisher","first-page":"2578","DOI":"10.1016\/j.immuni.2021.10.007","article-title":"Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity","volume":"54","author":"Vega-Perez","year":"2021","journal-title":"Immunity"},{"key":"B74","doi-asserted-by":"publisher","first-page":"e103454","DOI":"10.15252\/embj.2019103454","article-title":"Tissue-resident macrophages actively suppress il-1beta release via a reactive prostanoid\/il-10 pathway","volume":"39","author":"Ipseiz","year":"2020","journal-title":"EMBO J"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1007\/s10120-015-0579-8","article-title":"Tumor-associated macrophages of the M2 phenotype contribute to progression in gastric cancer with peritoneal dissemination","volume":"19","author":"Yamaguchi","year":"2016","journal-title":"Gastric Cancer"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00225","article-title":"Revisiting mouse peritoneal macrophages: heterogeneity, development, and function","volume":"6","author":"Cassado Ados","year":"2015","journal-title":"Front Immunol"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2024.1396000\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,12]],"date-time":"2024-08-12T00:31:22Z","timestamp":1723422682000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2024.1396000\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,12]]},"references-count":76,"alternative-id":["10.3389\/fimmu.2024.1396000"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2024.1396000","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,12]]},"article-number":"1396000"}}