{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:10:47Z","timestamp":1793193047350,"version":"4.5.0"},"reference-count":164,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T00:00:00Z","timestamp":1734566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007847","name":"Natural Science Foundation of Jilin Province","doi-asserted-by":"publisher","award":["YDZJ202201ZYTS029, YDZJ202201ZYTS110, YDZJ202201ZYTS067, 202512JC010480324"],"award-info":[{"award-number":["YDZJ202201ZYTS029, YDZJ202201ZYTS110, YDZJ202201ZYTS067, 202512JC010480324"]}],"id":[{"id":"10.13039\/100007847","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"abstract":"<jats:p>Long-term exposure of the peritoneum to peritoneal dialysate results in pathophysiological changes in the anatomical organization of the peritoneum and progressive development of peritoneal fibrosis. This leads to a decline in peritoneal function and ultrafiltration failure, ultimately necessitating the discontinuation of peritoneal dialysis, severely limiting the potential for long-term maintenance. Additionally, encapsulating peritoneal sclerosis, a serious consequence of peritoneal fibrosis, resulting in patients discontinuing PD and significant mortality. The causes and mechanisms underlying peritoneal fibrosis in patients undergoing peritoneal dialysis remain unknown, with no definitive treatment available. However, abnormal activation of the immune system appears to be involved in altering the structure of the peritoneum and promoting fibrotic changes. Macrophage infiltration and polarization are key contributors to pathological injury within the peritoneum, showing a strong correlation with the epithelial-to-mesenchymal transition of mesothelial cells and driving the process of fibrosis. This article discusses the role and mechanisms underlying macrophage activation-induced peritoneal fibrosis resulting from PD by analyzing relevant literature from the past decade and provides an overview of recent therapeutic approaches targeting macrophages to treat this condition.<\/jats:p>","DOI":"10.3389\/fimmu.2024.1507265","type":"journal-article","created":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T05:10:26Z","timestamp":1734585026000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":13,"title":["Mechanisms underlying the involvement of peritoneal macrophages in the pathogenesis and novel therapeutic strategies for dialysis-induced peritoneal fibrosis"],"prefix":"10.3389","volume":"15","author":[{"given":"Yangwei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yixian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingqi","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohua","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lining","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuehong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingchun","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenpeng","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,12,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.08.028","article-title":"Comparison of patient survival between hemodialysis and peritoneal dialysis among patients eligible for both modalities","volume":"71","author":"Wong","year":"2018","journal-title":"Am J Kidney Dis"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.37580","article-title":"Association between pretransplant dialysis modality and kidney transplant outcomes: A systematic review and meta-analysis","volume":"5","author":"Ngamvichchukorn","year":"2022","journal-title":"JAMA Netw Open"},{"key":"B3","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/nrneph.2016.181","article-title":"Changes in the worldwide epidemiology of peritoneal dialysis","volume":"13","author":"Li","year":"2017","journal-title":"Nat Rev Nephrol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1186\/s12955-020-01449-2","article-title":"Comparisons of quality of life between patients underwent peritoneal dialysis and hemodialysis: a systematic review and meta-analysis","volume":"18","author":"Chuasuwan","year":"2020","journal-title":"Health Qual Life Outcomes"},{"key":"B5","doi-asserted-by":"publisher","first-page":"F999","DOI":"10.1152\/ajprenal.00012.2016","article-title":"Peritoneal dialysis: from bench to bedside and bedside to bench","volume":"311","author":"Perl","year":"2016","journal-title":"Am J Physiol Renal Physiol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2016.04.016","article-title":"Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis","volume":"77","author":"Morinelli","year":"2016","journal-title":"Int J Biochem Cell Biol"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s40620-023-01759-w","article-title":"Peritoneal dialysis discontinuation: to the root of the problem","volume":"36","author":"Piarulli","year":"2023","journal-title":"J Nephrol"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2013.00074","article-title":"Encapsulating peritoneal sclerosis in the era of a multi-disciplinary approach based on biocompatible solutions: the NEXT-PD study","volume":"34","author":"Nakayama","year":"2014","journal-title":"Perit Dial Int"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0265584","article-title":"Risk factors for Encapsulating Peritoneal Sclerosis in patients undergoing peritoneal dialysis: A meta-analysis","volume":"17","author":"Li","year":"2022","journal-title":"PLoS One"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2017.00018","article-title":"Length of time on peritoneal dialysis and encapsulating peritoneal sclerosis - position paper for ISPD: 2017 update","volume":"37","author":"Brown","year":"2017","journal-title":"Perit Dial Int"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfv440","article-title":"Peritoneal inflammation precedes encapsulating peritoneal sclerosis: results from the GLOBAL Fluid Study","volume":"31","author":"Lambie","year":"2016","journal-title":"Nephrol Dial Transplant"},{"key":"B12","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1177\/08968608231196033","article-title":"Glucose-induced pseudohypoxia and advanced glycosylation end products explain peritoneal damage in long-term peritoneal dialysis","volume":"44","author":"Krediet","year":"2024","journal-title":"Perit Dial Int"},{"key":"B13","doi-asserted-by":"publisher","first-page":"115246","DOI":"10.1016\/j.biopha.2023.115246","article-title":"High glucose dialysate-induced peritoneal fibrosis: Pathophysiology, underlying mechanisms and potential therapeutic strategies","volume":"165","author":"Zhao","year":"2023","journal-title":"BioMed Pharmacother"},{"key":"B14","doi-asserted-by":"publisher","first-page":"Cd007554","DOI":"10.1002\/14651858.CD007554.pub3","article-title":"Biocompatible dialysis fluids for peritoneal dialysis","volume":"10","author":"Htay","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2018.02.022","article-title":"Neutral pH and low-glucose degradation product dialysis fluids induce major early alterations of the peritoneal membrane in children on peritoneal dialysis","volume":"94","author":"Schaefer","year":"2018","journal-title":"Kidney Int"},{"key":"B16","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1002\/path.v250.1","article-title":"Inflammatory macrophages switch to CCL17-expressing phenotype and promote peritoneal fibrosis","volume":"250","author":"Chen","year":"2020","journal-title":"J Pathol"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2017.12.023","article-title":"A pathogenetic role for M1 macrophages in peritoneal dialysis-associated fibrosis","volume":"94","author":"Li","year":"2018","journal-title":"Mol Immunol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.3390\/cells12172193","article-title":"Macrophage implication in IPF: updates on immune, epigenetic, and metabolic pathways","volume":"12","author":"Pokhreal","year":"2023","journal-title":"Cells"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathmechdis-012418-012718","article-title":"Diversity, mechanisms, and significance of macrophage plasticity","volume":"15","author":"Locati","year":"2020","journal-title":"Annu Rev Pathol"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2013.11.004","article-title":"Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways","volume":"26","author":"Zhou","year":"2014","journal-title":"Cell Signal"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.v233.9","article-title":"Macrophage plasticity, polarization, and function in health and disease","volume":"233","author":"Shapouri-Moghaddam","year":"2018","journal-title":"J Cell Physiol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"e21615","DOI":"10.1016\/j.heliyon.2023.e21615","article-title":"The potential role of miRNA in regulating macrophage polarization","volume":"9","author":"Khayati","year":"2023","journal-title":"Heliyon"},{"key":"B23","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.immuni.2014.06.013","article-title":"Origin and functions of tissue macrophages","volume":"41","author":"Epelman","year":"2014","journal-title":"Immunity"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2016.02.015","article-title":"Macrophages in tissue repair, regeneration, and fibrosis","volume":"44","author":"Wynn","year":"2016","journal-title":"Immunity"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-00541-3","article-title":"Macrophages and the maintenance of homeostasis","volume":"18","author":"Mosser","year":"2021","journal-title":"Cell Mol Immunol"},{"key":"B26","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1038\/s41419-023-06206-z","article-title":"Macrophage polarization and metabolism in atherosclerosis","volume":"14","author":"Hou","year":"2023","journal-title":"Cell Death Dis"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-022516-034339","article-title":"Macrophage polarization","volume":"79","author":"Murray","year":"2017","journal-title":"Annu Rev Physiol"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01084","article-title":"Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS-) vs. Alternatively Activated Macrophages","volume":"10","author":"Orecchioni","year":"2019","journal-title":"Front Immunol"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00614","article-title":"Molecular mechanisms that influence the macrophage m1-m2 polarization balance","volume":"5","author":"Wang","year":"2014","journal-title":"Front Immunol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"13","DOI":"10.12703\/P6-13","article-title":"The M1 and M2 paradigm of macrophage activation: time for reassessment","volume":"6","author":"Martinez","year":"2014","journal-title":"F1000Prime Rep"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1159\/000364945","article-title":"M1 and M2 macrophages: the chicken and the egg of immunity","volume":"6","author":"Mills","year":"2014","journal-title":"J Innate Immun"},{"key":"B32","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/s11658-022-00384-y","article-title":"The role of macrophage subtypes and exosomes in immunomodulation","volume":"27","author":"Gharavi","year":"2022","journal-title":"Cell Mol Biol Lett"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-020-01378-2","article-title":"Macrophage polarization and its role in the pathogenesis of acute lung injury\/acute respiratory distress syndrome","volume":"69","author":"Chen","year":"2020","journal-title":"Inflammation Res"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.867260","article-title":"The role of M1\/M2 macrophage polarization in rheumatoid arthritis synovitis","volume":"13","author":"Cutolo","year":"2022","journal-title":"Front Immunol"},{"key":"B35","doi-asserted-by":"publisher","first-page":"173090","DOI":"10.1016\/j.ejphar.2020.173090","article-title":"Macrophage M1\/M2 polarization","volume":"877","author":"Yunna","year":"2020","journal-title":"Eur J Pharmacol"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2019.03.062","article-title":"Attributes of alternatively activated (M2) macrophages","volume":"224","author":"Shrivastava","year":"2019","journal-title":"Life Sci"},{"key":"B37","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.3390\/cells13181586","article-title":"The contribution of macrophage plasticity to inflammatory arthritis and their potential as therapeutic targets","volume":"13","author":"Kulakova","year":"2024","journal-title":"Cells"},{"key":"B38","doi-asserted-by":"publisher","first-page":"816460","DOI":"10.1155\/2015\/816460","article-title":"Understanding the mysterious M2 macrophage through activation markers and effector mechanisms","volume":"2015","author":"R\u0151szer","year":"2015","journal-title":"Mediators Inflammation"},{"key":"B39","doi-asserted-by":"publisher","first-page":"Unit14.22","DOI":"10.1002\/0471142735.2011.93.issue-1","article-title":"Quantitative assessment of macrophage functions in repair and fibrosis","author":"Wynn","year":"2011","journal-title":"Curr Protoc Immunol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"7493","DOI":"10.3390\/ijms24087493","article-title":"Tumor-associated macrophage subsets: shaping polarization and targeting","volume":"24","author":"Zhang","year":"2023","journal-title":"Int J Mol Sci"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1103149","article-title":"Tumor-associated macrophage polarization in the inflammatory tumor microenvironment","volume":"13","author":"Zou","year":"2023","journal-title":"Front Oncol"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2100152","article-title":"Peritoneal dialysis","volume":"385","author":"Teitelbaum","year":"2021","journal-title":"N Engl J Med"},{"key":"B43","doi-asserted-by":"publisher","first-page":"8607","DOI":"10.3390\/ijms25168607","article-title":"Pathophysiological mechanisms of peritoneal fibrosis and peritoneal membrane dysfunction in peritoneal dialysis","volume":"25","author":"Ito","year":"2024","journal-title":"Int J Mol Sci"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1387292","article-title":"Sterile inflammation of peritoneal membrane caused by peritoneal dialysis: focus on the communication between immune cells and peritoneal stroma","volume":"15","author":"Su","year":"2024","journal-title":"Front Immunol"},{"key":"B45","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.immuni.2013.10.022","article-title":"Interleukin-6 signaling drives fibrosis in unresolved inflammation","volume":"40","author":"Fielding","year":"2014","journal-title":"Immunity"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/nri1733","article-title":"Monocyte and macrophage heterogeneity","volume":"5","author":"Gordon","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2705","article-title":"Tissue-resident macrophages","volume":"14","author":"Davies","year":"2013","journal-title":"Nat Immunol"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.31.7.645","article-title":"Output of peritoneal cells during peritoneal dialysis","volume":"31","author":"Fakhri","year":"1978","journal-title":"J Clin Pathol"},{"key":"B49","article-title":"Studies of human peritoneal cells: a normal saline lavage technique for the isolation and characterization of cells from peritoneal dialysis patients","volume":"27","author":"Ganguly","year":"1980","journal-title":"J Reticuloendothel Soc"},{"key":"B50","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2141.1999.1368h.x","article-title":"Why discard the peritoneal macrophages of patients on CAPD","volume":"105","author":"Humphries","year":"1999","journal-title":"Br J Haematol"},{"key":"B51","article-title":"Phenotypic characterization of monocytes and macrophages from CAPD patients","volume":"36","author":"Lewis","year":"1990","journal-title":"ASAIO Trans"},{"key":"B52","first-page":"16","article-title":"Host defence in continuous ambulatory peritoneal dialysis: the effect of the dialysate on phagocyte function","volume":"1","author":"Alobaidi","year":"1986","journal-title":"Nephrol Dial Transplant"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00538.2017","article-title":"Therapeutic potential of regulatory macrophages generated from peritoneal dialysate in adriamycin nephropathy","volume":"314","author":"Cao","year":"2018","journal-title":"Am J Physiol Renal Physiol"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2020.11130","article-title":"High glucose contributes to the polarization of peritoneal macrophages to the M2 phenotype in vivo and in vitro","volume":"22","author":"Lin","year":"2020","journal-title":"Mol Med Rep"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.10.030","article-title":"Peritoneal macrophage heterogeneity is associated with different peritoneal dialysis outcomes","volume":"91","author":"Liao","year":"2017","journal-title":"Kidney Int"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.v233.10","article-title":"The origins and homeostasis of monocytes and tissue-resident macrophages in physiological situation","volume":"233","author":"Zhao","year":"2018","journal-title":"J Cell Physiol"},{"key":"B57","doi-asserted-by":"publisher","first-page":"3675","DOI":"10.1038\/s41467-023-39173-2","article-title":"Selective oxidative protection leads to tissue topological changes orchestrated by macrophage during ulcerative colitis","volume":"14","author":"Du","year":"2023","journal-title":"Nat Commun"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.715209","article-title":"Ongoing exposure to peritoneal dialysis fluid alters resident peritoneal macrophage phenotype and activation propensity","volume":"12","author":"Sutherland","year":"2021","journal-title":"Front Immunol"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-019-01454-1","article-title":"TSPO modulates IL-4-induced microglia\/macrophage M2 polarization via PPAR-\u03b3 Pathway","volume":"70","author":"Zhou","year":"2020","journal-title":"J Mol Neurosci"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2019.11.077","article-title":"Microglial V-set and immunoglobulin domain-containing 4 protects against ischemic stroke in mice by suppressing TLR4-regulated inflammatory response","volume":"522","author":"Lyu","year":"2020","journal-title":"Biochem Biophys Res Commun"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.708186","article-title":"Macrophages: the good, the bad, and the gluttony","volume":"12","author":"Ross","year":"2021","journal-title":"Front Immunol"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2023.1220450","article-title":"A review of research progress on mechanisms of peritoneal fibrosis related to peritoneal dialysis","volume":"14","author":"Li","year":"2023","journal-title":"Front Physiol"},{"key":"B63","doi-asserted-by":"publisher","first-page":"4401","DOI":"10.3390\/jcm12134401","article-title":"Current insights into cellular determinants of peritoneal fibrosis in peritoneal dialysis: A narrative review","volume":"12","author":"Suryantoro","year":"2023","journal-title":"J Clin Med"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1159\/000453204","article-title":"The role of TLR4 in M1 macrophage-induced epithelial-mesenchymal transition of peritoneal mesothelial cells","volume":"40","author":"Shi","year":"2016","journal-title":"Cell Physiol Biochem"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1080\/08820139.2020.1828911","article-title":"Epithelial-mesenchymal transition of peritoneal mesothelial cells is enhanced by M2c macrophage polarization","volume":"51","author":"Tian","year":"2022","journal-title":"Immunol Invest"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-022-02297-8","article-title":"The expression of matrix metalloproteinase-12 in the peritoneum of rats with continuous peritoneal dialysis","volume":"27","author":"Hasegawa","year":"2023","journal-title":"Clin Exp Nephrol"},{"key":"B67","doi-asserted-by":"publisher","first-page":"2995","DOI":"10.1093\/ndt\/gfq771","article-title":"Alternative activation of macrophages in human peritoneum: implications for peritoneal fibrosis","volume":"26","author":"Bell\u00f3n","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.3390\/ijms140510369","article-title":"The role of peritoneal alternatively activated macrophages in the process of peritoneal fibrosis related to peritoneal dialysis","volume":"14","author":"Wang","year":"2013","journal-title":"Int J Mol Sci"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1111\/nep.v24.10","article-title":"Protective effects and mechanisms of omega-3 polyunsaturated fatty acid on intestinal injury and macrophage polarization in peritoneal dialysis rats","volume":"24","author":"Tang","year":"2019","journal-title":"Nephrol (Carlton)"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfy282","article-title":"Protein kinase C beta deficiency increases glucose-mediated peritoneal damage via M1 macrophage polarization and up-regulation of mesothelial protein kinase C alpha","volume":"34","author":"Balzer","year":"2019","journal-title":"Nephrol Dial Transplant"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2018.03.014","article-title":"Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution-induced fibrosis","volume":"94","author":"Raby","year":"2018","journal-title":"Kidney Int"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2020.08.014","article-title":"Toll-like receptor 4 plays a key role in advanced glycation end products-induced M1 macrophage polarization","volume":"531","author":"Liu","year":"2020","journal-title":"Biochem Biophys Res Commun"},{"key":"B73","doi-asserted-by":"publisher","first-page":"110180","DOI":"10.1016\/j.intimp.2023.110180","article-title":"A polysaccharide from Codonopsis pilosula roots attenuates carbon tetrachloride-induced liver fibrosis via modulation of TLR4\/NF-\u03baB and TGF-\u03b21\/Smad3 signaling pathway","volume":"119","author":"Meng","year":"2023","journal-title":"Int Immunopharmacol"},{"key":"B74","doi-asserted-by":"publisher","first-page":"155502","DOI":"10.1016\/j.phymed.2024.155502","article-title":"Jaceosidin attenuates the progression of hepatic fibrosis by inhibiting the VGLL3\/HMGB1\/TLR4 signaling pathway","volume":"128","author":"Yao","year":"2024","journal-title":"Phytomedicine"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2015080923","article-title":"Toll-like receptors 2 and 4 are potential therapeutic targets in peritoneal dialysis-associated fibrosis","volume":"28","author":"Raby","year":"2017","journal-title":"J Am Soc Nephrol"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.14232","article-title":"Emerging role of TWEAK-Fn14 axis in lupus, a disease related to autoimmunity and fibrosis","volume":"25","author":"Xu","year":"2022","journal-title":"Int J Rheum Dis"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.v236.5","article-title":"TWEAK\/Fn14 axis is an important player in fibrosis","volume":"236","author":"Zhang","year":"2021","journal-title":"J Cell Physiol"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-021-09688-4","article-title":"The TWEAK\/Fn14\/CD163 axis-implications for metabolic disease","volume":"23","author":"Ratajczak","year":"2022","journal-title":"Rev Endocr Metab Disord"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090399","article-title":"TWEAK promotes peritoneal inflammation","volume":"9","author":"Sanz","year":"2014","journal-title":"PloS One"},{"key":"B80","doi-asserted-by":"publisher","first-page":"2277","DOI":"10.3390\/cells9102277","article-title":"The impact of the CX3CL1\/CX3CR1 axis in neurological disorders","volume":"9","author":"Pawelec","year":"2020","journal-title":"Cells"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-024-00701-6","article-title":"Neutralization of CX3CL1 attenuates TGF-\u03b2-induced fibroblast differentiation through NF-\u03baB activation and mitochondrial dysfunction in airway fibrosis","volume":"202","author":"Cheng","year":"2024","journal-title":"Lung"},{"key":"B82","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1186\/s13075-024-03307-8","article-title":"Anti-CX3CL1 (fractalkine) monoclonal antibody attenuates lung and skin fibrosis in sclerodermatous graft-versus-host disease mouse model","volume":"26","author":"Hasegawa","year":"2024","journal-title":"Arthritis Res Ther"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.848310","article-title":"CX3CL1 worsens cardiorenal dysfunction and serves as a therapeutic target of canagliflozin for cardiorenal syndrome","volume":"13","author":"Zheng","year":"2022","journal-title":"Front Pharmacol"},{"key":"B84","doi-asserted-by":"publisher","first-page":"155272","DOI":"10.1016\/j.metabol.2022.155272","article-title":"CX3CL1\/CX3CR1 interaction protects against lipotoxicity-induced nonalcoholic steatohepatitis by regulating macrophage migration and M1\/M2 status","volume":"136","author":"Ni","year":"2022","journal-title":"Metabolism"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1402149","article-title":"CX3CR1 reduces kidney fibrosis by inhibiting local proliferation of profibrotic macrophages","volume":"194","author":"Engel","year":"2015","journal-title":"J Immunol"},{"key":"B86","doi-asserted-by":"publisher","first-page":"14556","DOI":"10.1038\/ncomms14556","article-title":"Sex differences in microglial CX3CR1 signalling determine obesity susceptibility in mice","volume":"8","author":"Dorfman","year":"2017","journal-title":"Nat Commun"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2018.12.030","article-title":"CX3CL1-CX3CR1 interaction mediates macrophage-mesothelial cross talk and promotes peritoneal fibrosis","volume":"95","author":"Helmke","year":"2019","journal-title":"Kidney Int"},{"key":"B88","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1186\/s13287-021-02270-4","article-title":"Adipose-derived mesenchymal stem cells attenuate dialysis-induced peritoneal fibrosis by modulating macrophage polarization via interleukin-6","volume":"12","author":"Yang","year":"2021","journal-title":"Stem Cell Res Ther"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1111\/nep.2017.22.issue-2","article-title":"Interleukin-6 trans-signalling induces vascular endothelial growth factor synthesis partly via Janus kinases-STAT3 pathway in human mesothelial cells","volume":"22","author":"Yang","year":"2017","journal-title":"Nephrol (Carlton)"},{"key":"B90","doi-asserted-by":"crossref","DOI":"10.1152\/ajprenal.00319.2019","article-title":"IL-6 trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane","volume":"318","author":"Yang","year":"2020","journal-title":"Am J Physiol Renal Physiol"},{"key":"B91","doi-asserted-by":"publisher","first-page":"107823","DOI":"10.1016\/j.intimp.2021.107823","article-title":"Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes","volume":"97","author":"Arabpour","year":"2021","journal-title":"Int Immunopharmacol"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0245169","article-title":"IL-10 and class 1 histone deacetylases act synergistically and independently on the secretion of proinflammatory mediators in alveolar macrophages","volume":"16","author":"Stanfield","year":"2021","journal-title":"PloS One"},{"key":"B93","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1186\/s12931-022-02134-2","article-title":"ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10","volume":"23","author":"Liu","year":"2022","journal-title":"Respir Res"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2019.1032","article-title":"The role of the anti-inflammatory cytokine interleukin-10 in tissue fibrosis","volume":"9","author":"Steen","year":"2020","journal-title":"Adv Wound Care (New Rochelle)"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1002\/JLB.3A0121-003RR","article-title":"B10 cells decrease fibrosis progression following cardiac injury partially by IL-10 production and regulating hyaluronan secretion","volume":"111","author":"Chen","year":"2022","journal-title":"J Leukoc Biol"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.02.026","article-title":"Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury","volume":"79","author":"Hackstein","year":"2023","journal-title":"J Hepatol"},{"key":"B97","doi-asserted-by":"publisher","first-page":"10702","DOI":"10.3390\/ijms231810702","article-title":"Interleukin-10 protects against ureteral obstruction-induced kidney fibrosis by suppressing endoplasmic reticulum stress and apoptosis","volume":"23","author":"Jung","year":"2022","journal-title":"Int J Mol Sci"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201646528","article-title":"IL-10 differentially controls the infiltration of inflammatory macrophages and antigen-presenting cells during inflammation","volume":"46","author":"Liao","year":"2016","journal-title":"Eur J Immunol"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2015.110","article-title":"Attenuation of methylglyoxal-induced peritoneal fibrosis: immunomodulation by interleukin-10","volume":"95","author":"Onishi","year":"2015","journal-title":"Lab Invest"},{"key":"B100","doi-asserted-by":"publisher","first-page":"156060","DOI":"10.1016\/j.cyto.2022.156060","article-title":"Monocyte chemotactic protein (MCP)-1 (CCL2) and its receptor (CCR2) are elevated in chronic heart failure facilitating lung monocyte infiltration and differentiation which may contribute to lung fibrosis","volume":"161","author":"Puukila","year":"2023","journal-title":"Cytokine"},{"key":"B101","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1186\/s12882-017-0490-0","article-title":"Biomarkers for the detection of renal fibrosis and prediction of renal outcomes: a systematic review","volume":"18","author":"Mansour","year":"2017","journal-title":"BMC Nephrol"},{"key":"B102","doi-asserted-by":"publisher","first-page":"2852398","DOI":"10.1155\/2018\/2852398","article-title":"Tubulointerstitial biomarkers for diabetic nephropathy","volume":"2018","author":"Satirapoj","year":"2018","journal-title":"J Diabetes Res"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2012.09.006","article-title":"The monocyte chemotactic protein synthesis inhibitor bindarit prevents mesangial cell proliferation and extracellular matrix remodeling","volume":"66","author":"Paccosi","year":"2012","journal-title":"Pharmacol Res"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.147464","article-title":"Urinary EGF and MCP-1 and risk of CKD after cardiac surgery","volume":"6","author":"Menez","year":"2021","journal-title":"JCI Insight"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0000000000000186","article-title":"Monocyte chemoattractant protein-1 and the kidney","volume":"25","author":"Haller","year":"2016","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00792","article-title":"Macrophage polarization in physiological and pathological pregnancy","volume":"10","author":"Yao","year":"2019","journal-title":"Front Immunol"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1111\/imcb.v101.7","article-title":"CCL17\/TARC in autoimmunity and inflammation-not just a T-cell chemokine","volume":"101","author":"Lupancu","year":"2023","journal-title":"Immunol Cell Biol"},{"key":"B108","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1053\/j.gastro.2016.02.040","article-title":"Tumor-associated neutrophils recruit macrophages and T-regulatory cells to promote progression of hepatocellular carcinoma and resistance to sorafenib","volume":"150","author":"Zhou","year":"2016","journal-title":"Gastroenterology"},{"key":"B109","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s40001-017-0299-0","article-title":"Chemokine ligand-receptor interactions critically regulate cutaneous wound healing","volume":"23","author":"B\u00fcnemann","year":"2018","journal-title":"Eur J Med Res"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2010.02353.x","article-title":"CCL18 in peritoneal dialysis patients and encapsulating peritoneal sclerosis","volume":"40","author":"Ahmad","year":"2010","journal-title":"Eur J Clin Invest"},{"key":"B111","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/bs.apha.2017.08.002","article-title":"Matrix metalloproteinases, vascular remodeling, and vascular disease","volume":"81","author":"Wang","year":"2018","journal-title":"Adv Pharmacol"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1124\/pharmrev.121.000349","article-title":"Matrix metalloproteinases: from molecular mechanisms to physiology, pathophysiology, and pharmacology","volume":"74","author":"de Almeida","year":"2022","journal-title":"Pharmacol Rev"},{"key":"B113","doi-asserted-by":"publisher","first-page":"115501","DOI":"10.1016\/j.bcp.2023.115501","article-title":"Therapeutic strategies targeting pro-fibrotic macrophages in interstitial lung disease","volume":"211","author":"Isshiki","year":"2023","journal-title":"Biochem Pharmacol"},{"key":"B114","doi-asserted-by":"crossref","DOI":"10.1042\/BST20140255","article-title":"Protein kinase C in cellular transformation: a valid target for therapy","volume":"42","author":"Tarafdar","year":"2014","journal-title":"Biochem Soc Trans"},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.01.025","article-title":"Protein kinase C \u03b1 inhibition prevents peritoneal damage in a mouse model of chronic peritoneal exposure to high-glucose dialysate","volume":"89","author":"Wang","year":"2016","journal-title":"Kidney Int"},{"key":"B116","doi-asserted-by":"publisher","first-page":"2074","DOI":"10.1038\/s41467-017-02092-0","article-title":"Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels","volume":"8","author":"Davies","year":"2017","journal-title":"Nat Commun"},{"key":"B117","doi-asserted-by":"publisher","first-page":"120283","DOI":"10.1016\/j.lfs.2021.120283","article-title":"Molecular pathways and role of epigenetics in the idiopathic pulmonary fibrosis","volume":"291","author":"Velagacherla","year":"2022","journal-title":"Life Sci"},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.5b00942","article-title":"Protein arginine methylation and citrullination in epigenetic regulation","volume":"11","author":"Fuhrmann","year":"2016","journal-title":"ACS Chem Biol"},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.1111\/tap.2014.18.issue-6","article-title":"Effect of DNA demethylation in experimental encapsulating peritoneal sclerosis","volume":"18","author":"Kim","year":"2014","journal-title":"Ther Apher Dial"},{"key":"B120","doi-asserted-by":"publisher","DOI":"10.1159\/000142529","article-title":"The role of the TGF\/Smad signaling pathway in peritoneal fibrosis induced by peritoneal dialysis solutions","volume":"109","author":"Yao","year":"2008","journal-title":"Nephron Exp Nephrol"},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.1016\/j.krcp.2016.07.003","article-title":"Experimental systems to study the origin of the myofibroblast in peritoneal fibrosis","volume":"35","author":"Padwal","year":"2016","journal-title":"Kidney Res Clin Pract"},{"key":"B122","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.090447","article-title":"Preventive effect of Notch signaling inhibition by a gamma-secretase inhibitor on peritoneal dialysis fluid-induced peritoneal fibrosis in rats","volume":"176","author":"Zhu","year":"2010","journal-title":"Am J Pathol"},{"key":"B123","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2015030299","article-title":"Inhibition of EGF receptor blocks the development and progression of peritoneal fibrosis","volume":"27","author":"Wang","year":"2016","journal-title":"J Am Soc Nephrol"},{"key":"B124","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.20982","article-title":"Histone deacetylase 6 inhibition counteracts the epithelial-mesenchymal transition of peritoneal mesothelial cells and prevents peritoneal fibrosis","volume":"8","author":"Xu","year":"2017","journal-title":"Oncotarget"},{"key":"B125","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012030226","article-title":"TGF-\u03b21 promotes lymphangiogenesis during peritoneal fibrosis","volume":"24","author":"Kinashi","year":"2013","journal-title":"J Am Soc Nephrol"},{"key":"B126","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1186\/s12967-021-02946-8","article-title":"STAT3\/HIF-1\u03b1 signaling activation mediates peritoneal fibrosis induced by high glucose","volume":"19","author":"Yang","year":"2021","journal-title":"J Transl Med"},{"key":"B127","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.16765","article-title":"Functional and therapeutic significance of EZH2 in urological cancers","volume":"8","author":"Liu","year":"2017","journal-title":"Oncotarget"},{"key":"B128","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2013.04.008","article-title":"Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells","volume":"23","author":"Kim","year":"2013","journal-title":"Cancer Cell"},{"key":"B129","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1002\/path.v250.1","article-title":"Genetic or pharmacologic blockade of enhancer of zeste homolog 2 inhibits the progression of peritoneal fibrosis","volume":"250","author":"Shi","year":"2020","journal-title":"J Pathol"},{"key":"B130","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2020.9073","article-title":"Protein acetylation and deacetylation: An important regulatory modification in gene transcription (Review)","volume":"20","author":"Xia","year":"2020","journal-title":"Exp Ther Med"},{"key":"B131","doi-asserted-by":"publisher","first-page":"890","DOI":"10.1080\/0886022X.2020.1811119","article-title":"Elevated expression of HDAC6 in clinical peritoneal dialysis patients and its pathogenic role on peritoneal angiogenesis","volume":"42","author":"Shi","year":"2020","journal-title":"Ren Fail"},{"key":"B132","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.722638","article-title":"Requirement of histone deacetylase 6 for interleukin-6 induced epithelial-mesenchymal transition, proliferation, and migration of peritoneal mesothelial cells","volume":"12","author":"Shi","year":"2021","journal-title":"Front Pharmacol"},{"key":"B133","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.899140","article-title":"Pharmacologic inhibition of histone deacetylase 6 prevents the progression of chlorhexidine gluconate-induced peritoneal fibrosis by blockade of M2 macrophage polarization","volume":"13","author":"Shi","year":"2022","journal-title":"Front Immunol"},{"key":"B134","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201801861R","article-title":"Blocking the histone lysine 79 methyltransferase DOT1L alleviates renal fibrosis through inhibition of renal fibroblast activation and epithelial-mesenchymal transition","volume":"33","author":"Liu","year":"2019","journal-title":"FASEB J"},{"key":"B135","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1038\/s41419-021-04365-5","article-title":"The histone methyltransferase DOT1L is a new epigenetic regulator of pulmonary fibrosis","volume":"13","author":"Yang","year":"2022","journal-title":"Cell Death Dis"},{"key":"B136","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-12-818948","article-title":"The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia","volume":"131","author":"Stein","year":"2018","journal-title":"Blood"},{"key":"B137","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s43556-023-00161-z","article-title":"The disruptor of telomeric silencing 1-like (DOT1L) promotes peritoneal fibrosis through the upregulation and activation of protein tyrosine kinases","volume":"5","author":"Tao","year":"2024","journal-title":"Mol BioMed"},{"key":"B138","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-023-00662-1","article-title":"Non-coding RNAs in disease: from mechanisms to therapeutics","volume":"25","author":"Nemeth","year":"2024","journal-title":"Nat Rev Genet"},{"key":"B139","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2015.03.050","article-title":"The expression profiling and ontology analysis of noncoding RNAs in peritoneal fibrosis induced by peritoneal dialysis fluid","volume":"564","author":"Liu","year":"2015","journal-title":"Gene"},{"key":"B140","doi-asserted-by":"publisher","first-page":"e3524","DOI":"10.1002\/jgm.v25.9","article-title":"Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun","volume":"25","author":"Shao","year":"2023","journal-title":"J Gene Med"},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2016.09.002","article-title":"Mechanism and regulation of NLRP3 inflammasome activation","volume":"41","author":"He","year":"2016","journal-title":"Trends Biochem Sci"},{"key":"B142","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2016070729","article-title":"The NLRP3 inflammasome has a critical role in peritoneal dialysis-related peritonitis","volume":"28","author":"Hautem","year":"2017","journal-title":"J Am Soc Nephrol"},{"key":"B143","doi-asserted-by":"publisher","first-page":"10363","DOI":"10.1038\/s41598-019-46504-1","article-title":"Crucial role of NLRP3 inflammasome in the development of peritoneal dialysis-related peritoneal fibrosis","volume":"9","author":"Hishida","year":"2019","journal-title":"Sci Rep"},{"key":"B144","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2013.50","article-title":"Mesenchymal stem cells: a new trend for cell therapy","volume":"34","author":"Wei","year":"2013","journal-title":"Acta Pharmacol Sin"},{"key":"B145","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2013.158","article-title":"Immunobiology of mesenchymal stem cells","volume":"21","author":"Ma","year":"2014","journal-title":"Cell Death Differ"},{"key":"B146","doi-asserted-by":"publisher","DOI":"10.3727\/096368916X694373","article-title":"Treatment of spinocerebellar ataxia with mesenchymal stem cells: A phase I\/IIa clinical study","volume":"26","author":"Tsai","year":"2017","journal-title":"Cell Transplant"},{"key":"B147","doi-asserted-by":"publisher","DOI":"10.1007\/s40620-014-0133-5","article-title":"Adipose-derived mesenchymal stem cells transplantation facilitate experimental peritoneal fibrosis repair by suppressing epithelial-mesenchymal transition","volume":"27","author":"Wakabayashi","year":"2014","journal-title":"J Nephrol"},{"key":"B148","doi-asserted-by":"publisher","first-page":"3768718","DOI":"10.1155\/2020\/3768718","article-title":"Adipose-derived mesenchymal stem cells modulate fibrosis and inflammation in the peritoneal fibrosis model developed in uremic rats","volume":"2020","author":"Costalonga","year":"2020","journal-title":"Stem Cells Int"},{"key":"B149","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-021-02818-7","article-title":"Potential impacts of diabetes mellitus and anti-diabetes agents on expressions of sodium-glucose transporters (SGLTs) in mice","volume":"74","author":"Hu","year":"2021","journal-title":"Endocrine"},{"key":"B150","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1998.00899.x","article-title":"Expression of glucose transporters in human peritoneal mesothelial cells","volume":"53","author":"Schr\u00f6ppel","year":"1998","journal-title":"Kidney Int"},{"key":"B151","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.lfs.2016.07.018","article-title":"Diabetes and exposure to peritoneal dialysis solutions alter tight junction proteins and glucose transporters of rat peritoneal mesothelial cells","volume":"161","author":"Debray-Garc\u00eda","year":"2016","journal-title":"Life Sci"},{"key":"B152","doi-asserted-by":"publisher","first-page":"1573","DOI":"10.3390\/biom10111573","article-title":"SGLT2 inhibition by intraperitoneal dapagliflozin mitigates peritoneal fibrosis and ultrafiltration failure in a mouse model of chronic peritoneal exposure to high-glucose dialysate","volume":"10","author":"Balzer","year":"2020","journal-title":"Biomolecules"},{"key":"B153","doi-asserted-by":"publisher","first-page":"3362","DOI":"10.3390\/nu14163362","article-title":"Omega-3 fatty acids for the management of osteoarthritis: A narrative review","volume":"14","author":"Cordingley","year":"2022","journal-title":"Nutrients"},{"key":"B154","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2017.1295870","article-title":"Disorders of serum omega-3 fatty acid composition in dialyzed patients, and their associations with fat mass","volume":"39","author":"Sikorska-Wi\u015bniewska","year":"2017","journal-title":"Ren Fail"},{"key":"B155","doi-asserted-by":"publisher","DOI":"10.3390\/ijms150712959","article-title":"Astragalus membranaceus inhibits peritoneal fibrosis via monocyte chemoattractant protein (MCP)-1 and the transforming growth factor-\u03b21 (TGF-\u03b21) pathway in rats submitted to peritoneal dialysis","volume":"15","author":"Li","year":"2014","journal-title":"Int J Mol Sci"},{"key":"B156","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/s00795-021-00305-6","article-title":"Mitochonic acid-5 ameliorates chlorhexidine gluconate-induced peritoneal fibrosis in mice","volume":"55","author":"Inoue","year":"2022","journal-title":"Med Mol Morphol"},{"key":"B157","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-021-02067-y","article-title":"Hepatocyte growth factor ameliorates methylglyoxal-induced peritoneal inflammation and fibrosis in mouse model","volume":"25","author":"Yoshimine","year":"2021","journal-title":"Clin Exp Nephrol"},{"key":"B158","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.724141","article-title":"Blockade of autophagy prevents the development and progression of peritoneal fibrosis","volume":"12","author":"Shi","year":"2021","journal-title":"Front Pharmacol"},{"key":"B159","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-018-1872-3","article-title":"Differences in peritoneal response after exposure to low-GDP bicarbonate\/lactate-buffered dialysis solution compared to conventional dialysis solution in a uremic mouse model","volume":"50","author":"Vila Cuenca","year":"2018","journal-title":"Int Urol Nephrol"},{"key":"B160","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0160993","article-title":"Linagliptin ameliorates methylglyoxal-induced peritoneal fibrosis in mice","volume":"11","author":"Nagai","year":"2016","journal-title":"PLoS One"},{"key":"B161","doi-asserted-by":"publisher","first-page":"6951","DOI":"10.3390\/ijms24086951","article-title":"The transfer of the hepatocyte growth factor gene by macrophages ameliorates the progression of peritoneal fibrosis in mice","volume":"24","author":"Obata","year":"2023","journal-title":"Int J Mol Sci"},{"key":"B162","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2014.69","article-title":"The aldosterone receptor antagonist spironolactone prevents peritoneal inflammation and fibrosis","volume":"94","author":"Zhang","year":"2014","journal-title":"Lab Invest"},{"key":"B163","doi-asserted-by":"publisher","first-page":"41901","DOI":"10.1038\/srep41901","article-title":"Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells","volume":"7","author":"Nita","year":"2017","journal-title":"Sci Rep"},{"key":"B164","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1186\/1471-2369-15-201","article-title":"Hepatocyte growth factor signalizes peritoneal membrane failure in peritoneal dialysis","volume":"15","author":"Bernardo","year":"2014","journal-title":"BMC Nephrol"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2024.1507265\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T05:10:35Z","timestamp":1734585035000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2024.1507265\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,19]]},"references-count":164,"alternative-id":["10.3389\/fimmu.2024.1507265"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2024.1507265","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,19]]},"article-number":"1507265"}}