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Immunol."],"abstract":"<jats:p>Pulmonary diseases, such as cystic fibrosis (CF), chronic obstructive pulmonary disease (COPD), and ventilator-associated pneumonia (VAP), are attributed to the prolonged infection of the airway and hypersecretion of mucus. <jats:italic>Pseudomonas aeruginosa<\/jats:italic> (PA) is one of the most common nosocomial pathogens in these diseased airways, secreting a wide spectrum of metabolites and volatile organic compounds (VOCs) that significantly impact the respiratory epithelium, including disruption of mucus homeostasis and inflammatory responses of the diseased lungs. 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