{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:16:00Z","timestamp":1787026560983,"version":"build-2736575974"},"reference-count":22,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T00:00:00Z","timestamp":1755043200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Synovitis\u2013acne\u2013pustulosis\u2013hyperostosis\u2013osteitis (SAPHO) syndrome is a rare autoimmune disorder. The involvement of spinal and sacroiliac joint in SAPHO syndrome closely resembles the manifestations of postpartum lumbopelvic pain (LPP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case presentation<\/jats:title>\n                    <jats:p>\n                      We report a case of a patient whose primary symptom was postpartum LPP, with recurrent episodes lasting 10 months without relief. Unexpectedly, she was diagnosed with SAPHO syndrome in the 11\n                      <jats:sup>th<\/jats:sup>\n                      month when she sought medical attention for severe palmoplantar pustulosis rather than LPP. After combined treatment with Tofacitinib citrate tablets and Etoricoxib tablets, all the pain symptoms disappeared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>For postpartum patients with concurrent palmoplantar scaling and recurrent LPP unresponsive to treatment, clinicians should consider SAPHO syndrome as a potential diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fimmu.2025.1614945","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T05:36:03Z","timestamp":1755063363000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Postpartum lumbopelvic pain could be SAPHO syndrome: a case report"],"prefix":"10.3389","volume":"16","author":[{"given":"Zheng","family":"Weiwei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhang","family":"Junhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhang","family":"Rong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,8,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-003-0615-y","article-title":"Pregnancy-related pelvic girdle pain (PPP), I: Terminology, clinical presentation, and prevalence","volume":"13","author":"Wu","year":"2004","journal-title":"Eur Spine J"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogc.2019.08.030","article-title":"Prevalence of low back pain, pelvic girdle pain, and combination pain in a postpartum ontario population","volume":"42","author":"Tavares","year":"2020","journal-title":"J Obstet Gynaecol Can"},{"key":"B3","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1186\/s12891-016-1154-0","article-title":"Predictors and consequences of long-term pregnancy-related pelvic girdle pain: a longitudinal follow-up study","volume":"17","author":"Elden","year":"2016","journal-title":"BMC Musculoskelet Disord"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1002\/art.42457","article-title":"Evolution of magnetic resonance imaging lesions at the sacroiliac joints during and after pregnancy by serial magnetic resonance imaging from gestational week twenty to twelve months postpartum","volume":"75","author":"Kiil","year":"2023","journal-title":"Arthritis Rheumatol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3579(94)80022-7","article-title":"The SAPHO syndrome","volume":"8","author":"Kahn","year":"1994","journal-title":"Baillieres Clin Rheumatol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1080\/14397595.2017.1372874","article-title":"Clinical features and radiological findings of 67 patients with SAPHO syndrome","volume":"28","author":"Okuno","year":"2018","journal-title":"Mod Rheumatol"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2013.10.010","article-title":"Disease burden, disease manifestations and current treatment regimen of the SAPHO syndrome in Germany: results from a nationwide patient survey","volume":"43","author":"Witt","year":"2014","journal-title":"Semin Arthritis Rheumatol"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.gyobfe.2006.10.013","article-title":"A pregnant woman with a SAPHO syndrome","volume":"34","author":"Ha","year":"2006","journal-title":"Gynecol Obstet Fertil"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(95)02588-X","article-title":"The course of the SAPHO syndrome during pregnancy","volume":"70","author":"Pons","year":"1996","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"B10","first-page":"S35","article-title":"Abstracts of the American College of Rheumatology 67th annual meeting and the Association of Rheumatology Health Professionals 38th annual meeting. 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