{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T04:57:21Z","timestamp":1781672241728,"version":"3.54.5"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01DK13567"],"award-info":[{"award-number":["R01DK13567"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"abstract":"<jats:p>Anti-myeloperoxidase (anti-MPO) antineutrophil cytoplasmic antibodies-associated vasculitis (AAV) manifests histologically as pauci-immune crescentic glomerulonephritis. Recurrent anti-MPO AAV after transplantation is rare and poorly understood. In this report, we describe a case of early recurrence of anti-MPO AAV in the kidney allograft of a patient who shared potentially permissive HLA antigens with the donor and who had detectable anti-MPO antibodies post-transplantation. We also share our experience with 13 additional cases of anti-MPO AAV in the native kidney who underwent kidney transplantation but did not develop recurrent disease. Clinicopathologic correlates, focusing on the potential association with post-transplant anti-MPO levels and permissive HLA antigens in the donors and recipients, are discussed. This report provides a brief examination of the immunopathologic features of anti-MPO AAV in the kidney allograft and underscores the potential importance of close monitoring for disease recurrence in patients presumed to be at increased risk for such complication.<\/jats:p>","DOI":"10.3389\/fimmu.2026.1713188","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T04:44:02Z","timestamp":1781671442000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case report: Recurrence of anti-myeloperoxidase pauci-immune crescentic glomerulonephritis in a kidney transplant recipient; potential association with HLA antigens and seropositivity?"],"prefix":"10.3389","volume":"17","author":[{"given":"Woojin James","family":"Chon","sequence":"first","affiliation":[{"name":"Department of Medicine, Hackensack Meridian School of Medicine","place":["Hackensack, NJ, United States"]},{"name":"Department of 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