{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T06:46:28Z","timestamp":1776062788544,"version":"3.50.1"},"reference-count":11,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T00:00:00Z","timestamp":1776038400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2026.1838269","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T05:48:09Z","timestamp":1776059289000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Editorial: Advances in therapeutic cancer vaccines-mechanisms and development"],"prefix":"10.3389","volume":"17","author":[{"given":"Mariam Mathew","family":"George","sequence":"first","affiliation":[{"name":"Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine","place":["New York, NY, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cory A.","family":"Brennick","sequence":"additional","affiliation":[{"name":"Carole and Ray Neag Comprehensive Cancer Center, University of Connecticut School of Medicine","place":["Farmington, CT, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James J.","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Michigan","place":["Ann Arbor, MI, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayon","family":"Lihm","sequence":"additional","affiliation":[{"name":"Memorial Sloan Kettering Cancer Center","place":["New York, NY, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyejin","family":"Choi","sequence":"additional","affiliation":[{"name":"Johnson & Johnson","place":["Spring House, PA, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,4,13]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.2217\/imt-2016-0146","article-title":"Neoepitopes as cancer immunotherapy targets: key challenges and opportunities","volume":"9","author":"Brennick","year":"2017","journal-title":"Immunotherapy"},{"key":"B2","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1038\/s41392-023-01674-3","article-title":"Therapeutic cancer vaccines: advancements, challenges and prospects","volume":"8","author":"Fan","year":"2023","journal-title":"Sig Transduct Target Ther"},{"key":"B3","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.cell.2020.08.053","article-title":"A phase ib trial of personalized neoantigen therapy plus anti-PD-1 in patients with advanced melanoma, non-small cell lung cancer, or bladder cancer","volume":"183","author":"Ott","year":"2020","journal-title":"Cell"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2023.07.006","article-title":"Randomized open-label controlled study of cancer vaccine OSE2101 versus chemotherapy in HLA-A2-positive patients with advanced non-small-cell lung cancer with resistance to immunotherapy: ATALANTE-1\u2606","volume":"34","author":"Besse","year":"2023","journal-title":"Ann Oncol"},{"key":"B5","doi-asserted-by":"crossref","DOI":"10.1016\/S0140-6736(23)02268-7","article-title":"Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study","volume":"403","author":"Weber","year":"2024","journal-title":"Lancet"},{"key":"B6","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0140-6736(25)00553-7","article-title":"Cancer vaccines and the future of immunotherapy","volume":"406","author":"Pail","year":"2025","journal-title":"Lancet"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-08508-4","article-title":"RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer","volume":"639","author":"Sethna","year":"2025","journal-title":"Nature"},{"key":"B8","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1097\/PAS.0000000000001653","article-title":"MHC class I loss in triple-negative breast cancer: A potential barrier to PD-1\/PD-L1 checkpoint inhibitors","volume":"45","author":"Dusenbery","year":"2021","journal-title":"Am J Surg Pathology"},{"key":"B9","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1038\/s41523-022-00468-0","article-title":"Triple negative breast cancer: Pitfalls and progress","volume":"8","author":"Zagami","year":"2022","journal-title":"NPJ Breast Cancer"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1153990","article-title":"Molecular mechanisms of immunotherapy resistance in triple-negative breast cancer","volume":"14","author":"Zheng","year":"2023","journal-title":"Front Immunol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2025.105111","article-title":"Research progress on immunotherapeutics for triple-negative breast cancer from a single-cell perspective","volume":"218","author":"Yuan","year":"2026","journal-title":"Crit Rev Oncology\/Hematology"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2026.1838269\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T05:48:10Z","timestamp":1776059290000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2026.1838269\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,13]]},"references-count":11,"alternative-id":["10.3389\/fimmu.2026.1838269"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2026.1838269","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,13]]},"article-number":"1838269"}}