{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T07:59:46Z","timestamp":1781164786758,"version":"3.54.1"},"reference-count":24,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the clinical characteristics and electromyographic findings of a patient with acetylcholine receptor (AChR) antibody-positive myasthenia gravis (MG) overlapping with Kennedy\u2019s disease (KD), aiming to improve clinicians\u2019 recognition of this rare overlap syndrome and explore potential comorbid mechanisms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The clinical presentation, laboratory results, and neurophysiological features of one case with AChR antibody-positive MG and KD were analyzed. A literature review of MG overlapping with KD was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Neurophysiological findings and androgen receptor gene testing results were consistent with a diagnosis of KD. Therefore, the patient was definitively diagnosed with overlap syndrome of AChR antibody-positive MG and KD. A literature review identified only four previously reported cases of KD patients exhibiting myasthenic features; however, all were AChR antibody-negative.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fimmu.2026.1872718","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T07:27:40Z","timestamp":1781162860000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Acetylcholine receptor antibody-positive myasthenia gravis and Kennedy\u2019s disease overlap syndrome: a case report and literature review"],"prefix":"10.3389","volume":"17","author":[{"given":"Guo-hui","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Shandong First Medical University &Shandong Provincial Qianfoshan Hospital","place":["Jinan, China"]},{"name":"Shandong Institute of Neuroimmunology","place":["Jinan, China"]},{"name":"Shandong Provincial Medicine and Health Key Laboratory of Neuroimmunology","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-qing","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Shandong First Medical University &Shandong Provincial Qianfoshan Hospital","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-dong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology, The First Affiliated Hospital of Shandong First Medical University &Shandong Provincial Qianfoshan Hospital","place":["Jinan, China"]},{"name":"Shandong Institute of Neuroimmunology","place":["Jinan, China"]},{"name":"Shandong Provincial Medicine and Health Key Laboratory of Neuroimmunology","place":["Jinan, 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