{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:23:52Z","timestamp":1791559432194,"version":"4.3.4"},"reference-count":43,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T00:00:00Z","timestamp":1788739200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"abstract":"<jats:p>Kawasaki disease (KD) is an acute systemic vasculitis that can affect multiple organs. Kawasaki disease shock syndrome (KDSS) is a severe complication of KD. Pulmonary involvement is uncommon in KD, and there are very few reports of patients with KD who develop KDSS and pulmonary lesions. This report presents the case of a 9-year-old boy who was hospitalized for fever, neck mass and rash, and was subsequently diagnosed with KDSS. During the administration of intravenous immunoglobulin (IVIG), he experienced acute dyspnea, which required urgent invasive mechanical ventilation and bronchoscopy. He was successfully weaned off ventilation shortly and recovered completely. No coronary dilatation or pulmonary fibrosis was detected at the 1-month post-discharge follow-up. This case suggests that KD can trigger rare but severe complications including KDSS and pulmonary involvement. The relationship between pulmonary complications, transfusion-related acute lung injury (TRALI) and transfusion-associated circulatory overload (TACO) remains to be further elucidated. Early aggressive management and comprehensive treatment may improve prognosis.<\/jats:p>","DOI":"10.3389\/fimmu.2026.1930430","type":"journal-article","created":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T05:33:27Z","timestamp":1788759207000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Kawasaki disease shock syndrome with pulmonary involvement in a child: a case report"],"prefix":"10.3389","volume":"17","author":[{"given":"Xuhua","family":"Xia","sequence":"first","affiliation":[{"name":"Department of Medical General Ward, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents\u2019 Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiwei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Medical General Ward, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents\u2019 Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Medical General Ward, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents\u2019 Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Medical General Ward, Children\u2019s Hospital of Chongqing Medical University, National Clinical Research Center for Children and Adolescents\u2019 Health and Diseases, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatric Metabolism and Inflammatory Diseases","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,7]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.210070","article-title":"Multisystem imaging manifestations of Kawasaki disease","volume":"42","author":"Tsujioka","year":"2022","journal-title":"Radiographics"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001295","article-title":"Update on diagnosis and management of 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