{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T06:02:32Z","timestamp":1789970552355,"version":"4.0.1"},"reference-count":23,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Immunol."],"DOI":"10.3389\/fimmu.2026.1985460","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T05:36:21Z","timestamp":1789968981000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Editorial: Infectious diseases in maternal-fetal interface: role of immune system to combat this pathology and avoid or minimize a possible vertical transmission"],"prefix":"10.3389","volume":"17","author":[{"given":"Bellisa Freitas","family":"Barbosa","sequence":"first","affiliation":[{"name":"Laboratory of Immunophysiology of Reproduction, Institute of Biomedical Science, Federal University of Uberl\u00e2ndia","place":["Uberl\u00e2ndia, MG, Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamba Omar","family":"Sangar\u00e9","sequence":"additional","affiliation":[{"name":"Department of Biology, Texas A&M University","place":["College Station, TX, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Kemmerling","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Science, School of Medicine, University of Chile","place":["Santiago, Chile"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-019-03104-6","article-title":"Human placenta and trophoblast development: key molecular mechanisms and model systems","volume":"76","author":"Knofler","year":"2019","journal-title":"Cell Mol Life Sci"},{"key":"B2","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1038\/s41574-020-0372-6","article-title":"Tracking placental development in health and disease","volume":"16","author":"Aplin","year":"2020","journal-title":"Nat Rev Endocrinol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1387\/ijdb.082759ja","article-title":"Developmental cell biology of human villous trophoblast: current research problems","volume":"54","author":"Aplin","year":"2010","journal-title":"Int J Dev Biol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1126\/sciimmunol.aat6114","article-title":"Immune responses at the maternal-fetal interface","volume":"4","author":"Ander","year":"2019","journal-title":"Sci Immunol"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2017.06.007","article-title":"The cytotrophoblastic shell and complications of pregnancy","volume":"60","author":"Burton","year":"2017","journal-title":"Placenta"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02597","article-title":"Regulation of placental extravillous trophoblasts by the maternal uterine environment","volume":"9","author":"Polheimer","year":"2018","journal-title":"Front Immunol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1242\/dev.163428","article-title":"Development of the human placenta","volume":"146","author":"Turco","year":"2019","journal-title":"Development"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2017.04.007","article-title":"Microbial vertical transmission during human pregnancy","volume":"21","author":"Arora","year":"2017","journal-title":"Cell Host Microbe"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ogc.2019.10.003","article-title":"Key infections in the placenta","volume":"47","author":"Costa","year":"2019","journal-title":"Obstet Gynecol Clin North Am"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-64029-1.00006-0","article-title":"Congenital and perinatal infections","volume":"162","author":"Ostrander","year":"2019","journal-title":"Handb Clin Neurol"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.02025","article-title":"T helper (Th) cell profiles in pregnancy and recurrent pregnancy losses: th1\/th2\/th9\/th17\/th22\/tfh cells","volume":"11","author":"Wang","year":"2020","journal-title":"Front Immunol"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/967629","article-title":"The Th1:th2 dichotomy of pregnancy and preterm labour","volume":"2012","author":"Sykes","year":"2012","journal-title":"Mediators Inflammation"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.2.539","article-title":"Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10","volume":"184","author":"Roth","year":"1996","journal-title":"J Exp Med"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.05.013","article-title":"Cytokines and chemokines production by mononuclear cells from parturient women after stimulation with live Toxoplasma gondii","volume":"33","author":"Rezende-Oliveira","year":"2012","journal-title":"Placenta"},{"key":"B15","doi-asserted-by":"crossref","DOI":"10.1016\/S0002-9378(99)70400-X","article-title":"Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition","volume":"181","author":"Keelan","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0378(03)00045-7","article-title":"Th1\/Th2 balance in preeclampsia","volume":"59","author":"Saito","year":"2003","journal-title":"J Reprod Immunol"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaw1300","article-title":"The immunological code of pregnancy","volume":"365","author":"Colucci","year":"2019","journal-title":"Science"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.3201\/eid1211.060152","article-title":"Emerging infections and pregnancy","volume":"12","author":"Jamieson","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.semperi.2024.151919","article-title":"Impact of SARS-CoV-2 infection during pregnancy on the placenta and fetus","volume":"48","author":"Li","year":"2024","journal-title":"Semin Perinatol"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1177\/10668969211067754","article-title":"SARS-CoV-2 immunohistochemistry in placenta","volume":"30","author":"Rakheja","year":"2022","journal-title":"Int J Surg Pathol"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3201\/eid2803.211735","article-title":"Detection of SARS-CoV-2 in neonatal autopsy tissues and placenta","volume":"28","author":"Reagan-Steiner","year":"2022","journal-title":"Emerg Infect Dis"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpam.2019.05.004","article-title":"Vertically transmitted chikungunya, Zika and dengue virus infections: The pathogenesis from mother to fetus and the implications of co-infections and vaccine development","volume":"7","author":"Evans-Gilbert","year":"2020","journal-title":"Int J Pediatr Adolesc Med"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.1055536","article-title":"Histopathological and immunological characteristics of placentas infected with chikungunya v\u00edrus","volume":"17","author":"Salom\u00e3o","year":"2022","journal-title":"Front Microbiol"}],"container-title":["Frontiers in Immunology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2026.1985460\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T05:36:22Z","timestamp":1789968982000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fimmu.2026.1985460\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,21]]},"references-count":23,"alternative-id":["10.3389\/fimmu.2026.1985460"],"URL":"https:\/\/doi.org\/10.3389\/fimmu.2026.1985460","relation":{},"ISSN":["1664-3224"],"issn-type":[{"value":"1664-3224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,21]]},"article-number":"1985460"}}