{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T14:50:16Z","timestamp":1774450216996,"version":"3.50.1"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"DOI":"10.3389\/fmed.2020.00338","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T04:19:02Z","timestamp":1598588342000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":24,"title":["Maternal and Neonatal Complications After Natural vs. Hormone Replacement Therapy Cycle Regimen for Frozen Single Blastocyst Transfer"],"prefix":"10.3389","volume":"7","author":[{"given":"Jia","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junzhao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guimin","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jichun","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ye","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ze","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ning","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhua","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,8,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1016\/j.fertnstert.2016.06.017","article-title":"Elective single embryo transfer in women less than age 38 years reduces multiple birth rates, but not live birth rates, in United States fertility clinics","volume":"106","author":"Mancuso","year":"2016","journal-title":"Fertil Steril."},{"key":"B2","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/j.fertnstert.2018.02.135","article-title":"Programming the endometrium for deferred transfer of cryopreserved embryos: hormone replacement versus modified natural cycles","volume":"109","author":"Groenewoud","year":"2018","journal-title":"Fertil Steril."},{"key":"B3","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1056\/NEJMoa1513873","article-title":"Fresh versus Frozen embryos for infertility in the polycystic ovary syndrome","volume":"375","author":"Chen","year":"2016","journal-title":"N Engl J Med."},{"key":"B4","doi-asserted-by":"publisher","first-page":"2735","DOI":"10.1210\/jc.2018-00613","article-title":"The effect of supraphysiological estradiol on pregnancy outcomes differs between women with PCOS and ovulatory women","volume":"103","author":"Wei","year":"2018","journal-title":"J Clin Endocrinol Metab."},{"key":"B5","first-page":"CD002118","article-title":"Cleavage stage versus blastocyst stage embryo transfer in assisted reproductive technology","volume-title":"Cochrane Database Syst Rev.","author":"Glujovsky","year":"2016"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.1016\/S0140-6736(18)32843-5","article-title":"Frozen versus fresh single blastocyst transfer in ovulatory women: a multicentre, randomised controlled trial","volume":"393","author":"Wei","year":"2019","journal-title":"Lancet."},{"key":"B7","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.fertnstert.2013.09.025","article-title":"Impact of frozen-thawed single-blastocyst transfer on maternal and neonatal outcome: an analysis of 277,042 single-embryo transfer cycles from 2008 to 2010 in Japan","volume":"101","author":"Ishihara","year":"2014","journal-title":"Fertil Steril."},{"key":"B8","doi-asserted-by":"publisher","first-page":"618","DOI":"10.1093\/humrep\/det440","article-title":"Large baby syndrome in singletons born after frozen embryo transfer (FET): is it due to maternal factors or the cryotechnique?","volume":"29","author":"Pinborg","year":"2014","journal-title":"Hum Reprod."},{"key":"B9","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s10815-010-9530-4","article-title":"Use of the natural cycle and vitrification thawed blastocyst transfer results in better in-vitro fertilization outcomes","volume":"28","author":"Chang","year":"2011","journal-title":"J Assist Reprod Genet."},{"key":"B10","doi-asserted-by":"publisher","first-page":"70","DOI":"10.3109\/09513590.2014.958988","article-title":"The artificial cycle method improves the pregnancy outcome in frozen\u2013thawed embryo transfer: a retrospective cohort study","volume":"31","author":"Zheng","year":"2014","journal-title":"Gynecol Endocrinol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1007\/s10815-015-0499-x","article-title":"Frozen blastocyst embryo transfer using a supplemented natural cycle protocol has a similar live birth rate compared to a programmed cycle protocol","volume":"32","author":"Lathi","year":"2015","journal-title":"J Assist Reprod Genet."},{"key":"B12","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1016\/j.fertnstert.2018.05.013","article-title":"Impact of method of endometrial preparation for frozen blastocyst transfer on pregnancy outcome: a retrospective cohort study","volume":"110","author":"Alur-Gupta","year":"2018","journal-title":"Fertil Steril."},{"key":"B13","doi-asserted-by":"publisher","first-page":"CD003414","DOI":"10.1002\/14651858.CD003414.pub3","article-title":"Cycle regimens for frozen-thawed embryo transfer","volume":"7","author":"Ghobara","year":"2017","journal-title":"Cochrane Database Syst Rev."},{"key":"B14","doi-asserted-by":"publisher","first-page":"126.e1","DOI":"10.1016\/j.ajog.2019.03.010","article-title":"Neonatal and maternal outcome after frozen embryo transfer: increased risks in programmed cycles","volume":"221","author":"Ginstrom Ernstad","year":"2019","journal-title":"Am J Obstet Gynecol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1007\/s10815-019-01420-1","article-title":"Increased pregnancy complications following frozen-thawed embryo transfer during an artificial cycle","volume":"36","author":"Jing","year":"2019","journal-title":"J Assist Reprod Genet."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1016\/j.humpath.2015.04.007","article-title":"Morphologic characteristics of the placental basal plate in in vitro fertilization pregnancies: a possible association with the amount of bleeding in delivery","volume":"46","author":"Nakamura","year":"2015","journal-title":"Hum Pathol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1186\/s13063-017-1993-5","article-title":"Live birth after fresh versus frozen single blastocyst transfer (Frefro-blastocyst): study protocol for a randomized controlled trial","volume":"18","author":"Wei","year":"2017","journal-title":"Trials."},{"key":"B18","doi-asserted-by":"publisher","first-page":"e104779","DOI":"10.1371\/journal.pone.0104779","article-title":"Birth weight reference percentiles for Chinese","volume":"9","author":"Dai","year":"2014","journal-title":"PLoS ONE."},{"key":"B19","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1093\/humrep\/dew120","article-title":"A randomized controlled, non-inferiority trial of modified natural versus artificial cycle for cryo-thawed embryo transfer","volume":"31","author":"Groenewoud","year":"2016","journal-title":"Hum Reprod."},{"key":"B20","doi-asserted-by":"publisher","first-page":"e0020","DOI":"10.5041\/RMMJ.10297","article-title":"Impact of endometrial preparation protocols for Frozen embryo transfer on live birth rates","volume":"8","author":"Cerrillo","year":"2017","journal-title":"Rambam Maimonides Med J."},{"key":"B21","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1007\/s10815-017-0869-7","article-title":"Increased incidence of post-term delivery and Cesarean section after frozen-thawed embryo transfer during a hormone replacement cycle","volume":"34","author":"Saito","year":"2017","journal-title":"J Assist Reprod Genet."},{"key":"B22","doi-asserted-by":"publisher","first-page":"2234","DOI":"10.1093\/humrep\/dex285","article-title":"Frozen embryo transfer: a review on the optimal endometrial preparation and timing","volume":"32","author":"Mackens","year":"2017","journal-title":"Hum Reprod."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1007\/s10815-016-0787-0","article-title":"Preparation of endometrium for frozen embryo replacement cycles: a systematic review and meta-analysis","volume":"33","author":"Yarali","year":"2016","journal-title":"J Assist Reprod Genet."},{"key":"B24","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.fertnstert.2017.06.015","article-title":"Increased rates of complications in singleton pregnancies of women previously diagnosed with polycystic ovary syndrome predominantly in the hyperandrogenic phenotype","volume":"108","author":"De Wilde","year":"2017","journal-title":"Fertil Steril."},{"key":"B25","doi-asserted-by":"publisher","first-page":"18","DOI":"10.3760\/cma.j.issn.0529-567X.2018.01.005","article-title":"Effect of hyperandrogenism on obstetric complications of singleton pregnancy from in vitro fertilization in women with polycystic ovary syndrome","volume":"53","author":"Wei","year":"2018","journal-title":"Zhonghua Fu Chan Ke Za Zhi."},{"key":"B26","doi-asserted-by":"publisher","first-page":"494","DOI":"10.3109\/09513590.2014.900032","article-title":"Comparison between two protocols for thawed embryo transfer: natural cycle versus exogenous hormone replacement","volume":"30","author":"Levron","year":"2014","journal-title":"Gynecol Endocrinol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.fertnstert.2018.06.020","article-title":"Programmed versus natural frozen embryo transfer: which is the best nest?","volume":"110","author":"Kang","year":"2018","journal-title":"Fertil Steril."},{"key":"B28","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1016\/j.fertnstert.2016.01.006","article-title":"Optimal endometrial preparation for frozen embryo transfer cycles: window of implantation and progesterone support","volume":"105","author":"Casper","year":"2016","journal-title":"Fertil Steril."},{"key":"B29","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1016\/j.rbmo.2016.03.004","article-title":"Endometrial transcriptome analysis indicates superiority of natural over artificial cycles in recurrent implantation failure patients undergoing frozen embryo transfer","volume":"32","author":"Altmae","year":"2016","journal-title":"Reprod Biomed Online."},{"key":"B30","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1093\/humupd\/dmw046","article-title":"What is the optimal means of preparing the endometrium in frozen-thawed embryo transfer cycles? A systematic review and meta-analysis","volume":"19","author":"Groenewoud","year":"2017","journal-title":"Hum Reprod Update"},{"key":"B31","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.fertnstert.2008.11.027","article-title":"A GnRH agonist and exogenous hormone stimulation protocol has a higher live-birth rate than a natural endogenous hormone protocol for frozen-thawed blastocyst-stage embryo transfer cycles: an analysis of 1391 cycles","volume":"93","author":"Hill","year":"2010","journal-title":"Fertil Steril."},{"key":"B32","first-page":"513","article-title":"Evaluation of clinical factors influencing pregnancy rate in frozen embryo transfer","volume":"12","author":"Eftekhar","year":"2014","journal-title":"Iran J Reprod Med."},{"key":"B33","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1016\/j.fertnstert.2014.01.040","article-title":"Effect of preovulatory progesterone elevation and duration of progesterone elevation on the pregnancy rate of frozen\u2013thawed embryo transfer in natural cycles","volume":"101","author":"Lee","year":"2014","journal-title":"Fertil Steril."},{"key":"B34","doi-asserted-by":"publisher","first-page":"2803","DOI":"10.1093\/humrep\/dew263","article-title":"Frozen\u2013thawed embryo transfers in natural cycles with spontaneous or induced ovulation: the search for the best protocol continues","volume":"31","author":"Montagut","year":"2016","journal-title":"Hum Reprod."},{"key":"B35","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1161\/HYPERTENSIONAHA.118.12046","article-title":"Absent or excessive corpus luteum number is associated with altered maternal vascular health in early pregnancy","volume":"73","author":"Von","year":"2019","journal-title":"Hypertension."},{"key":"B36","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1002\/rmb2.12206","article-title":"Identifying a possible factor for the increased newborn size in singleton pregnancies after assisted reproductive technology using cryopreserved embryos, in comparison with fresh embryos","volume":"17","author":"Ishii","year":"2018","journal-title":"Reprod Med Biol."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmed.2020.00338\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T04:19:05Z","timestamp":1598588345000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmed.2020.00338\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,28]]},"references-count":36,"alternative-id":["10.3389\/fmed.2020.00338"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2020.00338","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,28]]},"article-number":"338"}}