{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:43:03Z","timestamp":1761129783843,"version":"3.41.2"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T00:00:00Z","timestamp":1605484800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"DOI":"10.3389\/fmed.2020.556818","type":"journal-article","created":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T07:37:45Z","timestamp":1605512265000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical Characteristics of Patients With Progressive and Non-progressive Coronavirus Disease 2019: Evidence From 365 Hospitalised Patients in Honghu and Nanchang, China"],"prefix":"10.3389","volume":"7","author":[{"given":"Yanpei","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu-shan","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongbo","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenyi","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Feng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing-can","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng-ying","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan-shan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wan-li","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han-yi","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengchun","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Lin","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2020,11,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1001\/jama.2020.1585","article-title":"Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus\u2013infected pneumonia in Wuhan, China","volume":"323","author":"Wang","year":"2020","journal-title":"JAMA."},{"key":"B2","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/S0140-6736(20)30154-9","article-title":"A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster","volume":"395","author":"Chan","year":"2020","journal-title":"Lancet."},{"key":"B3","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet."},{"key":"B4","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1016\/S0140-6736(20)30211-7","article-title":"Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study","volume":"395","author":"Chen","year":"2020","journal-title":"Lancet."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1097\/CM9.0000000000000744","article-title":"Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province","volume":"133","author":"Liu","year":"2020","journal-title":"Chin Med J."},{"key":"B6","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/S2213-2600(20)30079-5","article-title":"Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study","volume":"8","author":"Yang","year":"2020","journal-title":"Lancet Respir Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1001\/jama.2020.2648","article-title":"Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention","volume":"323","author":"Wu","year":"2020","journal-title":"JAMA."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1056\/NEJMoa2001316","article-title":"Early transmission dynamics in Wuhan, China, of novel coronavirus\u2013infected pneumonia","volume":"382","author":"Li","year":"2020","journal-title":"New Engl J Med"},{"key":"B9","doi-asserted-by":"publisher","first-page":"2000058","DOI":"10.2807\/1560-7917.ES.2020.25.4.2000058","article-title":"Pattern of early human-to-human transmission of Wuhan 2019 novel coronavirus (2019-nCoV), December 2019 to January 2020","volume":"25","author":"Riou","year":"2020","journal-title":"Eurosurveillance."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.2139\/ssrn.3548753","article-title":"Characteristics and associations with severity in COVID-19 patients: a multicentre cohort study from Jiangsu Province, China","author":"Liu","year":"2020","journal-title":"China"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1101\/2020.02.10.20021584","article-title":"Neutrophil-to-lymphocyte ratio predicts severe illness patients with 2019 novel coronavirus in the early stage","author":"Liu","year":"2020","journal-title":"MedRxiv."},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1101\/2020.03.17.20037515","article-title":"A tool to early predict severe 2019-novel coronavirus pneumonia (COVID-19): a multicenter study using the risk Nomogram in Wuhan and Guangdong, China","author":"Gong","year":"2020","journal-title":"medRxiv."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1097\/CM9.0000000000000819","article-title":"Diagnosis and treatment protocol for novel coronavirus pneumonia (Trial Version 7)","volume":"133","year":"2020","journal-title":"Chin Med J."},{"key":"B14","doi-asserted-by":"publisher","first-page":"e95","DOI":"10.1016\/j.jinf.2020.04.008","article-title":"Risk factors associated with disease severity and length of hospital stay in COVID-19 patients","volume":"81","author":"Liu","year":"2020","journal-title":"J Infect."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.1056\/NEJMc2005073","article-title":"SARS-CoV-2 infection in children","volume":"382","author":"Lu","year":"2020","journal-title":"New Engl J Med."},{"key":"B16","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1002\/jmv.25783","article-title":"Clinical features and treatment of COVID-19 patients in Northeast Chongqing","volume":"92","author":"Wan","year":"2020","journal-title":"J Med Virol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1101\/2020.02.06.20020974","article-title":"Clinical characteristics of coronavirus disease 2019 in China","volume":"382","author":"Guan","year":"2020","journal-title":"New Engl J Med."},{"key":"B18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2214\/AJR.20.23034","article-title":"Coronavirus disease 2019 (COVID-19): a systematic review of imaging findings in 919 patients","volume":"215","author":"Salehi","year":"2020","journal-title":"Am J Roentgenol."},{"key":"B19","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1038\/s41586-020-2012-7","article-title":"A pneumonia outbreak associated with a new coronavirus of probable bat origin","volume":"579","author":"Zhou","year":"2020","journal-title":"Nature."},{"key":"B20","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1101\/2020.02.18.20023242","article-title":"Kidney disease is associated with in-hospital death of patients with COVID-19","volume":"97","author":"Cheng","year":"2020","journal-title":"Kidney Int."},{"key":"B21","doi-asserted-by":"publisher","first-page":"1805","DOI":"10.1172\/JCI200318921","article-title":"C-reactive protein: a critical update","volume":"111","author":"Pepys","year":"2003","journal-title":"J Clin Invest."},{"key":"B22","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1002\/jmv.25871","article-title":"C-reactive protein correlates with computed tomographic findings and predicts severe COVID-19 early","volume":"92","author":"Tan","year":"2020","journal-title":"J Med Virol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"104370","DOI":"10.1016\/j.jcv.2020.104370","article-title":"Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19","volume":"127","author":"Liu","year":"2020","journal-title":"J Clin Virol."},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn311365-20200211-00055","article-title":"Clinical analysis of risk factors for severe patients with novel coronavirus pneumonia [J\/OL]","author":"Ling","year":"2020"},{"key":"B25","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/s41569-020-0360-5","article-title":"COVID-19 and the cardiovascular system","volume":"17","author":"Zheng","year":"2020","journal-title":"Nat Rev Cardiol."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2020.556818\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,16]],"date-time":"2020-11-16T07:37:47Z","timestamp":1605512267000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2020.556818\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,16]]},"references-count":25,"alternative-id":["10.3389\/fmed.2020.556818"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2020.556818","relation":{},"ISSN":["2296-858X"],"issn-type":[{"type":"electronic","value":"2296-858X"}],"subject":[],"published":{"date-parts":[[2020,11,16]]},"article-number":"556818"}}