{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T14:32:42Z","timestamp":1793975562951,"version":"4.8.0"},"reference-count":20,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003785","name":"Guangdong Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003785","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p><jats:bold>Objective:<\/jats:bold> To evaluate the performance of transvaginal ultrasonography (TVS) in diagnosis of deep infiltrating endometriosis (DIE).<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> We retrospectively analyzed 198 patients with pathological diagnosis of DIE in our hospital from January 2017 to December 2019 and assessed the performances of pre-operative TVS diagnosis of DIE with regarding to sensitivity (SE), specificity (SP), positive predictive value (PPV), and negative predictive value (NPV), using the pathological diagnosis as the ground truth. We also characterized the ultrasonographic features of the DIE lesions.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Among all the 198 cases, 170 cases were uterosacral ligament (USL) involvement, SE: 96.47% and SP: 85.71%; 79 cases were intestinal involvement, SE: 94.94% and SP: 94.96%; 57 cases were vaginal rectal septum (VRS) involvement, SE: 73.68% and SP: 94.33%; 20 cases were vaginal involvement, SE: 50% and SP: 97.21%; three cases were bladder involvement, SE: 66.7% and SP: 100%; nine cases were ureter involvement, SE: 55.56% and SP: 100%; and 10 cases were broad ligament involvement, SE: 10% and SP: 100%.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> TVS showed high accuracy in diagnosing DIE.<\/jats:p>","DOI":"10.3389\/fmed.2020.567929","type":"journal-article","created":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T07:32:06Z","timestamp":1606116726000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":18,"title":["Diagnosis of Deep Infiltrating Endometriosis Using Transvaginal Ultrasonography"],"prefix":"10.3389","volume":"7","author":[{"given":"Shaoli","family":"Yin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanhua","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinfeng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1016\/j.fertnstert.2012.07.1061","article-title":"Deep endometriosis: definition, diagnosis, and treatment","volume":"98","author":"Koninckx","year":"2012","journal-title":"Fertil Steril"},{"key":"B2","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1093\/humrep\/deg009","article-title":"Anatomical distribution of deeply infiltrating endometriosis: surgical implications and proposition for a classification","volume":"18","author":"Chapron","year":"2003","journal-title":"Hum Reprod"},{"key":"B3","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1002\/uog.4070","article-title":"Accuracy of transvaginal sonography and rectal endoscopic sonography in the diagnosis of deep infiltrating endometriosis","volume":"30","author":"Bazot","year":"2007","journal-title":"Ultrasound Obstet Gynecol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.fertnstert.2011.05.090","article-title":"Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries","volume":"96","author":"Nnoaham","year":"2011","journal-title":"Fertil Steril"},{"key":"B5","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1080\/01443615.2019.1603217","article-title":"Diagnostic delay for superficial and deep endometriosis in the United Kingdom","volume":"40","author":"Ghai","year":"2020","journal-title":"J Obstet Gynaecol"},{"key":"B6","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1002\/uog.15955","article-title":"Systematic approach to sonographic evaluation of the pelvis in women with suspected endometriosis, including terms, definitions and measurements: a consensus opinion from the International Deep Endometriosis Analysis (IDEA) group","volume":"48","author":"Guerriero","year":"2016","journal-title":"Ultrasound Obstet Gynecol"},{"key":"B7","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.bpobgyn.2018.01.013","article-title":"Ultrasound diagnosis of endometriosis and adenomyosis: state of the art","volume":"51","author":"Van den Bosch","year":"2018","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1002\/uog.1108","article-title":"Diagnostic accuracy of transvaginal sonography for deep pelvic endometriosis","volume":"24","author":"Bazot","year":"2004","journal-title":"Ultrasound Obstet Gynecol"},{"key":"B9","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/S0889-8545(05)70310-7","article-title":"Surgical treatment of endometriosis","volume":"24","author":"Adamson","year":"1997","journal-title":"Obstet Gynecol Clin North Am"},{"key":"B10","first-page":"516","article-title":"Laparoscopic treatment of cul-de-sac obliteration secondary to retrocervical deep fifibrotic endometriosis","volume":"36","author":"Reich","year":"1991","journal-title":"J Reprod Med"},{"key":"B11","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1055\/s-0036-1597127","article-title":"Ultrasound imaging for ovarian and deep infiltrating endometriosis","volume":"35","author":"Exacoustos","year":"2017","journal-title":"Semin Reprod Med"},{"key":"B12","doi-asserted-by":"publisher","first-page":"2014","DOI":"10.1093\/oxfordjournals.humrep.a019535","article-title":"Evaluation of endometriosis in uterosacral ligaments by transrectal ultrasonography","volume":"11","author":"Ohba","year":"1996","journal-title":"Hum Reprod"},{"key":"B13","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1002\/uog.15667","article-title":"Accuracy of transvaginal ultrasound for diagnosis of deep endometriosis in uterosacral ligaments, rectovaginal septum, vagina and bladder: systematic review and meta-analysis","volume":"46","author":"Guerriero","year":"2015","journal-title":"Ultrasound Obstet Gynecol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1002\/uog.8858","article-title":"Diagnostic accuracy of transvaginal ultrasound for non-invasive diagnosis of bowel endometriosis: systematic review and meta-analysis","volume":"37","author":"Hudelist","year":"2011","journal-title":"Ultrasound Obstet Gynecol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"5958402","DOI":"10.1155\/2019\/5958402","article-title":"Sonographic differential diagnosis in deep infiltrating endometriosis: the bowel","volume":"2019","author":"Scioscia","year":"2019","journal-title":"BioMed Res Int"},{"key":"B16","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1002\/uog.7356","article-title":"Diagnostic accuracy and potential limitations of transvaginal sonography for bladder endometriosis","volume":"34","author":"Savelli","year":"2009","journal-title":"Ultrasound Obstet Gynecol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1348","DOI":"10.1016\/j.fertnstert.2017.04.013","article-title":"Endometriosis on the uterosacral ligament: a marker of ureteral involvement","volume":"107","author":"Lima","year":"2017","journal-title":"Fertil Steril"},{"key":"B18","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1093\/humrep\/deu360","article-title":"Histological evaluation of ureteral involvement in women with deep infiltrating endometriosis: analysis of a large series","volume":"30","author":"Seracchioli","year":"2015","journal-title":"Hum Reprod"},{"key":"B19","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1002\/uog.17524","article-title":"Role of transvaginal ultrasound in evaluation of ureteral involvement in deep infiltrating endometriosis","volume":"51","author":"Carfagna","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.jmig.2019.08.027","article-title":"Sonographic evaluation for endometriosis in routine pelvic ultrasound","volume":"27","author":"Piessens","year":"2019","journal-title":"J Minim Invasive Gynecol"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2020.567929\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T07:32:08Z","timestamp":1606116728000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2020.567929\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,23]]},"references-count":20,"alternative-id":["10.3389\/fmed.2020.567929"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2020.567929","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,23]]},"article-number":"567929"}}