{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T20:35:08Z","timestamp":1788986108465,"version":"build-2803163510"},"reference-count":39,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T00:00:00Z","timestamp":1600819200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"DOI":"10.3389\/fmed.2020.574651","type":"journal-article","created":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T06:12:55Z","timestamp":1600841575000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":27,"title":["Hypertension Risk in Young Women With Polycystic Ovary Syndrome: A Nationwide Population-Based Cohort Study"],"prefix":"10.3389","volume":"7","author":[{"given":"Cheng-Hsuan","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu-Ting","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Jun","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-I","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maw-Sheng","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsung-Hsien","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James Cheng-Chung","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,9,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.fertnstert.2003.10.004","article-title":"Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome","volume":"81","author":"Rotterdam","year":"2004","journal-title":"Fertil Steril."},{"key":"B2","doi-asserted-by":"publisher","first-page":"16057","DOI":"10.1038\/nrdp.2016.57","article-title":"Polycystic ovary syndrome","volume":"2","author":"Azziz","year":"2016","journal-title":"Nat Rev Dis Primers."},{"key":"B3","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1016\/j.fertnstert.2018.08.021","article-title":"Beyond fertility: polycystic ovary syndrome and long-term health","volume":"110","author":"Cooney","year":"2018","journal-title":"Fertil Steril."},{"key":"B4","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1111\/cen.12986","article-title":"Influence of race\/ethnicity on cardiovascular risk factors in polycystic ovary syndrome, the Dallas Heart Study","volume":"85","author":"Chang","year":"2016","journal-title":"Clin Endocrinol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1080\/09513590.2019.1650337","article-title":"Cardiovascular events among reproductive and menopausal age women with polycystic ovary syndrome: a systematic review and meta-analysis","volume":"36","author":"Ramezani Tehrani","year":"2020","journal-title":"Gynecol Endocrinol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1016\/j.fertnstert.2018.08.046","article-title":"Cardiometabolic risks in polycystic ovary syndrome: long-term population-based follow-up study","volume":"110","author":"Behboudi-Gandevani","year":"2018","journal-title":"Fertil Steril."},{"key":"B7","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1111\/cen.14117","article-title":"The cardiovascular risk profile of middle-aged women with polycystic ovary syndrome","volume":"92","author":"Meun","year":"2020","journal-title":"Clin Endocrinol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1016\/j.fertnstert.2016.12.017","article-title":"Normo- and hyperandrogenic women with polycystic ovary syndrome exhibit an adverse metabolic profile through life","volume":"107","author":"Pinola","year":"2017","journal-title":"Fertil Steril."},{"key":"B9","doi-asserted-by":"publisher","first-page":"8756","DOI":"10.18632\/oncotarget.23985","article-title":"Coronary artery disease risk in young women with polycystic ovary syndrome","volume":"9","author":"Ding","year":"2018","journal-title":"Oncotarget."},{"key":"B10","doi-asserted-by":"publisher","first-page":"5592","DOI":"10.1210\/jc.2004","article-title":"Endothelial dysfunction in young women with polycystic ovary syndrome: relationship with insulin resistance and low-grade chronic inflammation","volume":"89","author":"Tarkun","year":"2004","journal-title":"J Clin Endocrinol Metab."},{"key":"B11","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s12933","article-title":"Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome","volume":"17","author":"Glintborg","year":"2018","journal-title":"Cardiovasc Diabetol."},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2019.08.010","article-title":"Polycystic ovary syndrome and cardiometabolic risk: opportunities for cardiovascular disease prevention","author":"Osibogun","year":"","journal-title":"Trends Cardiovasc Med."},{"key":"B13","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1093\/ajh\/hpu251","article-title":"Hypertension in reproductive-aged women with polycystic ovary syndrome and association with obesity","volume":"28","author":"Joham","year":"2015","journal-title":"Am J Hypertens."},{"key":"B14","doi-asserted-by":"publisher","first-page":"583","DOI":"10.2217\/17455057.4.6.583","article-title":"Role of androgen excess on metabolic aberrations and cardiovascular risk in women with polycystic ovary syndrome","volume":"4","author":"Christakou","year":"2008","journal-title":"Womens Health."},{"key":"B15","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s12958-020-00576-1","article-title":"Risk of hypertension in women with polycystic ovary syndrome: a systematic review, meta-analysis and meta-regression","volume":"18","author":"Amiri","year":"2020","journal-title":"Reprod Biol Endocrinol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.fertnstert.2018.09.013","article-title":"Metabolic disturbances in non-obese women with polycystic ovary syndrome: a systematic review and meta-analysis","volume":"111","author":"Zhu","year":"2019","journal-title":"Fertil Steril."},{"key":"B17","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1007\/s11906-018-0864-0","article-title":"Treatment of hypertension in chronic kidney disease","volume":"20","author":"Kalaitzidis","year":"2018","journal-title":"Curr Hypertens Rep."},{"key":"B18","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/s11306-018-1408-y","article-title":"Metabolomic characterization of hypertension and dyslipidemia","volume":"14","author":"Ke","year":"2018","journal-title":"Metabolomics."},{"key":"B19","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1111\/jch.12638","article-title":"Diabetes and hypertension: a comparative review of current guidelines","volume":"18","author":"Cryer","year":"2016","journal-title":"J Clin Hypertens."},{"key":"B20","doi-asserted-by":"publisher","first-page":"16302","DOI":"10.1038\/s41598-019-52762-w","article-title":"Comorbidity of asthma and hypertension may be mediated by shared genetic dysregulation and drug side effects","volume":"9","author":"Zolotareva","year":"2019","journal-title":"Sci Rep."},{"key":"B21","doi-asserted-by":"publisher","first-page":"e367","DOI":"10.1093\/geront\/gnz062","article-title":"The impact of retirement on cardiovascular disease and its risk factors: a systematic review of longitudinal studies","volume":"60","author":"Xue","year":"2020","journal-title":"Gerontologist."},{"key":"B22","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/j.tjog.2019.05.003","article-title":"Dyslipidemia involvement in the development of polycystic ovary syndrome","volume":"58","author":"Liu","year":"2019","journal-title":"Taiwan J Obstet Gynecol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"e13461","DOI":"10.14814\/phy2.13461","article-title":"Consequences of advanced aging on renal function in chronic hyperandrogenemic female rat model: implications for aging women with polycystic ovary syndrome","volume":"5","author":"Patil","year":"2017","journal-title":"Physiol Rep."},{"key":"B24","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.rmed.2016.08.025","article-title":"Coexistence of asthma and polycystic ovary syndrome: a concise review","volume":"119","author":"Zierau","year":"2016","journal-title":"Respir Med."},{"key":"B25","doi-asserted-by":"publisher","first-page":"e030318","DOI":"10.1136\/bmjopen-2019-030318","article-title":"Female reproductive history in relation to chronic obstructive pulmonary disease and lung function in UK biobank: a prospective population-based cohort study","volume":"9","author":"Tang","year":"2019","journal-title":"BMJ Open."},{"key":"B26","doi-asserted-by":"publisher","first-page":"e0140544","DOI":"10.1371\/journal.pone.0140544","article-title":"Relationship between polycystic ovarian syndrome and subsequent gestational diabetes mellitus: a nationwide population-based study","volume":"10","author":"Pan","year":"2015","journal-title":"PLoS ONE."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1830","DOI":"10.1093\/humrep\/dez081","article-title":"Association between depression risk and polycystic ovarian syndrome in young women: a retrospective nationwide population-based cohort study (1998-2013)","volume":"34","author":"Harnod","year":"2019","journal-title":"Hum Reprod."},{"key":"B28","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/j.fertnstert.2018.11.034","article-title":"ACC\/AHA 2017 definition of high blood pressure: implications for women with polycystic ovary syndrome","volume":"111","author":"Marchesan","year":"2019","journal-title":"Fertil Steril."},{"key":"B29","doi-asserted-by":"publisher","first-page":"55","DOI":"10.2174\/1573402115666190531071422","article-title":"Hypertension in polycystic ovary syndrome: novel insights","volume":"16","author":"Macut","year":"2020","journal-title":"Curr Hypertens Rev."},{"key":"B30","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.1210\/jc.2007-0190","article-title":"Obesity is the major determinant of the abnormalities in blood pressure found in young women with the polycystic ovary syndrome","volume":"92","author":"Luque-Ramirez","year":"2007","journal-title":"J Clin Endocrinol Metab."},{"key":"B31","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s12020-016-0958-x","article-title":"Hyperinsulinemia and obese phenotype differently influence blood pressure in young normotensive patients with polycystic ovary syndrome","volume":"55","author":"Mioni","year":"2017","journal-title":"Endocrine."},{"key":"B32","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.fertnstert.2012.08.049","article-title":"Cardiac autonomic modulation in polycystic ovary syndrome: does the phenotype matter?","volume":"99","author":"Di Domenico","year":"2013","journal-title":"Fertil Steril."},{"key":"B33","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1210\/er.2011-1034","article-title":"Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications","volume":"33","author":"Diamanti-Kandarakis","year":"2012","journal-title":"Endocr Rev."},{"key":"B34","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1152\/physiol.00030.2016","article-title":"Cardiometabolic features of polycystic ovary syndrome: role of androgens","volume":"32","author":"Yanes Cardozo","year":"2017","journal-title":"Physiology."},{"key":"B35","doi-asserted-by":"publisher","first-page":"2038","DOI":"10.1210\/jc.2009-2724","article-title":"Assessment of cardiovascular risk and prevention of cardiovascular disease in women with the polycystic ovary syndrome: a consensus statement by the androgen excess and polycystic ovary syndrome (AE-PCOS) society","volume":"95","author":"Wild","year":"2010","journal-title":"J Clin Endocrinol Metab."},{"key":"B36","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1080\/13697137.2017.1316256","article-title":"Are women with polycystic ovary syndrome at increased cardiovascular disease risk later in life?","volume":"20","author":"Gunning","year":"2017","journal-title":"Climacteric."},{"key":"B37","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1097\/AOG.0000000000002698","article-title":"Polycystic ovary syndrome","volume":"132","author":"Azziz","year":"2018","journal-title":"Obstet Gynecol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1093\/humrep\/dey256","article-title":"Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome","volume":"33","author":"Teede","year":"2018","journal-title":"Hum Reprod."},{"key":"B39","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1007\/s10995-019-02746-z","article-title":"Effect of parity on pregnancy-associated hypertension among Asian American women in the United States","volume":"23","author":"Li","year":"2019","journal-title":"Matern Child Health J."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmed.2020.574651\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,23]],"date-time":"2020-09-23T06:12:57Z","timestamp":1600841577000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fmed.2020.574651\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,23]]},"references-count":39,"alternative-id":["10.3389\/fmed.2020.574651"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2020.574651","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,23]]},"article-number":"574651"}}