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Decreased life quality and secondary complications, caused by an itch-related disruption of the epidermal barrier and subsequent superinfections, illustrate the need to treat scabies and to understand the underlying mechanisms of itch in respective patients. This review summarizes available data on itch in scabies with a special focus on the clinical aspects and its underlying pathomechanisms.<\/jats:p>","DOI":"10.3389\/fmed.2021.628392","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T04:35:33Z","timestamp":1612154133000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":30,"title":["Itch in Scabies\u2014What Do We Know?"],"prefix":"10.3389","volume":"8","author":[{"given":"Sascha","family":"St\u00e4nder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"St\u00e4nder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,2,1]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/j.jaad.2019.05.109","article-title":"Ectoparasites: 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