{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T22:20:52Z","timestamp":1793485252118,"version":"4.5.0"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:00:00Z","timestamp":1637539200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>A bee sting can lead to an extremely rare case of visual loss caused by central retinal artery occlusion (CRAO). In this study, we report a 66-year-old healthy woman who was referred to our Eye Center because of visual loss, which had occurred after bee sting 2 days earlier. The visual acuity was no light perception (NLP). Examination revealed left eyelid edema, conjunctiva congestion, a 6-mm fixed pupil, scattered retinal hemorrhage, and white-appearing ischemic retina with one small area of the normal-appearing retina temporal to the optic disk. Fundus fluorescein angiography revealed CRAO with one cilioretinal artery sparing. Her systemic workup revealed hypersensitivity, hypercoagulable state, myocardial damage, and hepatic damage. After topical and systemic treatments, the visual acuity was still NLP with improved systemic workup. In brief, CRAO may occur after bee sting, and visual acuity should be monitored for early diagnosis.<\/jats:p>","DOI":"10.3389\/fmed.2021.707978","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:23:24Z","timestamp":1637540604000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Visual Loss Caused by Central Retinal Artery Occlusion After Bee Sting: A Case Report"],"prefix":"10.3389","volume":"8","author":[{"given":"Zhitao","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongli","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyun","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panpan","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,11,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/eye.2013.25","article-title":"A review of central retinal artery occlusion: clinical presentation and management","volume":"27","author":"Varma","year":"2013","journal-title":"Eye."},{"key":"B2","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1136\/emj.17.5.324","article-title":"Acute occlusion of the retinal arteries: current concepts and recent advances in diagnosis and management","volume":"17","author":"Beatty","year":"2000","journal-title":"J Accid Emerg Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1684","DOI":"10.4103\/ijo.IJO_1446_18","article-title":"Central retinal artery occlusion","volume":"66","author":"Hayreh","year":"2018","journal-title":"Indian J Ophthalmol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/s12016-014-8434-y","article-title":"Unusual reactions to hymenoptera stings: what should we keep in mind?","volume":"47","author":"Mingomataj","year":"2014","journal-title":"Clin Rev Allergy Immunol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"e1035","DOI":"10.7759\/cureus.1035","article-title":"A case series of bee sting keratopathy with different outcomes in Malaysia","volume":"9","author":"Ang","year":"2017","journal-title":"Cureus."},{"key":"B6","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1097\/ICO.0b013e3181f234a6","article-title":"Bee sting of the cornea and conjunctiva: management and outcomes","volume":"30","author":"Lin","year":"2011","journal-title":"Cornea."},{"key":"B7","doi-asserted-by":"publisher","first-page":"155","DOI":"10.5694\/mja17.01202","article-title":"Bee sting to the cornea: toxic effects and management","volume":"209","author":"Olivo Payne","year":"2018","journal-title":"Med J Aust."},{"key":"B8","doi-asserted-by":"publisher","first-page":"461","DOI":"10.4103\/ijo.IJO_889_17","article-title":"Successful management of bee sting induced Aspergillus fumigatus endophthalmitis and scleritis","volume":"66","author":"Dogra","year":"2018","journal-title":"Indian J Ophthalmol."},{"key":"B9","doi-asserted-by":"publisher","first-page":"112","DOI":"10.4103\/ojo.ojo_27_21","article-title":"Case report of central retinal artery occlusion following bee sting injury: a possible link?","volume":"14","author":"Pujari","year":"2021","journal-title":"Oman J Ophthalmol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"107","DOI":"10.4168\/aair.2012.4.2.107","article-title":"A fatal case of intravascular coagulation after bee sting acupuncture","volume":"4","author":"Jung","year":"2012","journal-title":"Allergy Asthma Immunol Res."},{"key":"B11","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1126\/science.177.4046.314","article-title":"Bee and wasp venoms","volume":"177","author":"Habermann","year":"1972","journal-title":"Science."},{"key":"B12","first-page":"342","article-title":"Bee sting of the cornea: case report","volume":"14","author":"Smolin","year":"1982","journal-title":"Ann Ophthalmol."},{"key":"B13","first-page":"285","article-title":"Bee sting-induced ocular changes","volume":"18","author":"Chen","year":"1986","journal-title":"Ann Ophthalmol."},{"key":"B14","first-page":"157","article-title":"Wasp sting-induced retinal damage","volume":"25","author":"Kitagawa","year":"1993","journal-title":"Ann Ophthalmol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"100080","DOI":"10.1016\/j.waojou.2019.100080","article-title":"IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper","volume":"13","author":"Ansotegui","year":"2020","journal-title":"World Allergy Organ J."},{"key":"B16","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1097\/mbc.0000000000000025","article-title":"Acute stent thrombosis and\/or atrial fibrillation occurring after bee sting","volume":"25","author":"Kahraman","year":"2014","journal-title":"Blood Coagul Fibrinolysis."},{"key":"B17","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1136\/bjo.61.10.662","article-title":"Bee and wasp stings of the eye. Retained intralenticular wasp sting: a case report","volume":"61","author":"Gilboa","year":"1977","journal-title":"Br J Ophthal."},{"key":"B18","doi-asserted-by":"publisher","first-page":"672","DOI":"10.1097\/00003226-200310000-00011","article-title":"Corneal honeybee sting","volume":"22","author":"Al-Towerki","year":"2003","journal-title":"Cornea."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2021.707978\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T00:23:28Z","timestamp":1637540608000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2021.707978\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,22]]},"references-count":18,"alternative-id":["10.3389\/fmed.2021.707978"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2021.707978","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,22]]},"article-number":"707978"}}