{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:19:42Z","timestamp":1791389982457,"version":"4.3.3"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T00:00:00Z","timestamp":1637193600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p><jats:bold>Background:<\/jats:bold> Malaria among pregnant women is one of the major causes of maternal and infant mortality and morbidity, especially in high-risk areas. Therefore, our study identified the burden of malaria for pregnant women, non-pregnant women, and children under 5 years of age, and malaria service health facilities in Bannu district, Khyber Pakhtunkhwa, Pakistan.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> A cross-sectional study was conducted. In this survey, 15,650 individuals were surveyed, and 1,283 were malaria-positive detected. The data were collected from 80 different healthcare centers. SPSS version 23 was used for data analysis. ArcGIS version 10.8 was used for study area mapping.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Malaria was detected in 23.3% of children under five, 4.4% of pregnant women, and 72.3% of non-pregnant women, respectively. Moreover, <jats:italic>P. falciparum, P. vivax<\/jats:italic>, and mixed infection had a prevalence of 2.1, 96.8, and 1.1%. The most often used and effective medications to treat malaria were chloroquine (29.7%) and primaquine (69.4%).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> This study's findings depict that malaria's prevalence in the non-pregnant women's group was high. Additionally, <jats:italic>P. vivax<\/jats:italic> infection was found to be more prevalent than other types of malaria infection. Due to the scarcity of healthcare facilities in this endemic region, special attention should be directed to strengthening the malaria surveillance and eradication programs.<\/jats:p>","DOI":"10.3389\/fmed.2021.751456","type":"journal-article","created":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T05:45:51Z","timestamp":1637214351000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Passive Surveillance of Malaria in Pregnant Women, Non-pregnant Women and Children Under 5 Years of Age in Bannu District, Khyber Pakhtunkhwa Pakistan"],"prefix":"10.3389","volume":"8","author":[{"given":"Humera","family":"Qureshi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Imran","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akhlaq","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usman Ayub","family":"Awan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aamer Ali","family":"Khattak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayesha Ali","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqiong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,11,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/S1473-3099(11)70315-2","article-title":"Malaria in pregnancy in the Asia-Pacific region","volume":"12","author":"Rijken MJ","year":"2012","journal-title":"Lancet Infect Dis."},{"key":"B2","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/s12936-016-1125-9","article-title":"Malaria in pregnancy: a passive surveillance study of pregnant women in low transmission areas of Colombia, Latin America","volume":"15","author":"Mary","year":"2016","journal-title":"Malaria Journal"},{"key":"B3","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1186\/s12936-017-2077-4","article-title":"Risk factors and pregnancy outcomes associated with placental malaria in a prospective cohort of Papua New Guinean women","volume":"16","author":"Elvin Lufele","year":"2017","journal-title":"Malaria Journal"},{"key":"B4","unstructured":"The burden of malaria in pregnancy in Madhya Pradesh, India\n            AhmedR\n          19210797Liverpool School of Tropical Medicine.2011"},{"key":"B5","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1186\/1475-2875-9-290","article-title":"Imported malaria in an area in southern Madrid, 2005-2008","volume":"9","author":"Rey S","year":"2010","journal-title":"Malaria Journal"},{"key":"B6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1475-2875-11-29","article-title":"The complexities of malaria disease manifestations with a focus on asymptomatic malaria","volume":"11","author":"Laishram","year":"2012","journal-title":"Malar J."},{"key":"B7","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1586\/eri.13.45","article-title":"The silent threat: asymptomatic parasitemia and malaria transmission","volume":"11","author":"Lindblade","year":"2013","journal-title":"Expert Rev Anti Infect Ther."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12936-017-1809-9","article-title":"New developments in anti-malarial target candidate and product profiles","volume":"16","author":"Burrows","year":"2017","journal-title":"Malar J."},{"key":"B9","doi-asserted-by":"publisher","first-page":"175","DOI":"10.15406\/ipcb.2018.04.00122","article-title":"Afolabi AO. 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