{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T16:42:34Z","timestamp":1767890554013,"version":"3.49.0"},"reference-count":15,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T00:00:00Z","timestamp":1638144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Beijing Municipal Natural Science Foundation","doi-asserted-by":"publisher","award":["7192207"],"award-info":[{"award-number":["7192207"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019018","name":"Chinese Academy of Medical Sciences Initiative for Innovative Medicine","doi-asserted-by":"publisher","award":["2019-I2M-5-046"],"award-info":[{"award-number":["2019-I2M-5-046"]}],"id":[{"id":"10.13039\/501100019018","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>In this research, we described a very rare case of secondary lupus nephritis associated with B-cell lymphoma. An 84-year-old man was hospitalized at our institute for lower extremity edema persisting for over 2 months. He was diagnosed with systemic lupus erythematosus based on clinical and laboratory criteria, which showed impaired renal function and nephrotic syndrome with predominant hematuria. Renal biopsy showed IV+V lupus nephritis with highly infiltrated lymphoid cells in the kidney. Secondary lupus nephritis was suspected based on the possible pathogenesis of glomerular injury due to mantle cell lymphoma. Low-dose dexamethasone, rituximab, and lenalidomide were immediately started on the patient, and his renal function was improved after the first cycle of chemotherapy.<\/jats:p>","DOI":"10.3389\/fmed.2021.759279","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T12:27:28Z","timestamp":1638361648000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Case Report: A Rare Case of Lupus Nephritis Associated With Mantle Cell Lymphoma"],"prefix":"10.3389","volume":"8","author":[{"given":"Daorina","family":"Bao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojuan","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingjie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fude","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minghui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,11,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1038\/s41572-019-0141-9","article-title":"Lupus nephritis","volume":"6","author":"Anders","year":"2020","journal-title":"Nat Rev Dis Primers."},{"key":"B2","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.jbspin.2018.10.007","article-title":"Rare diseases that mimic Systemic Lupus Erythematosus (Lupus mimickers)","volume":"86","author":"Chasset","year":"2019","journal-title":"Joint Bone Spine."},{"key":"B3","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1177\/0961203312467668","article-title":"Lupus nephritis and non-Hodgkin lymphoma simultaneously diagnosed in a patient on methimazole","volume":"22","author":"Lionaki","year":"2013","journal-title":"Lupus."},{"key":"B4","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1186\/1471-2369-14-158","article-title":"An unusual case of glomerulonephritis in a patient with non-Hodgkin Mucosal Associated Lymphoid Tissue (MALT) B-cell lymphoma","volume":"14","author":"Yeo","year":"2013","journal-title":"BMC Nephrol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1097\/RHU.0000000000000649","article-title":"The first case of lupus nephritis developing in a patient with mantle cell lymphoma","volume":"24","author":"Horino","year":"2018","journal-title":"J Clin Rheumatol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"001734","DOI":"10.12890\/2020_001734","article-title":"Angioimmunoblastic T-cell lymphoma: a mimic for lupus","volume":"7","author":"Tay","year":"2020","journal-title":"Eur J Case Rep Intern Med."},{"key":"B7","doi-asserted-by":"publisher","first-page":"360","DOI":"10.3109\/14397595.2014.974880","article-title":"Systemic lupus erythematosus as the concomitant manifestation of angioimmunoblastic T-cell lymphoma","volume":"27","author":"Suzuki","year":"2017","journal-title":"Mod Rheumatol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"2054358118793397","DOI":"10.1177\/2054358118793397","article-title":"Late-onset systemic lupus erythematosus with lupus nephritis in a 74-year-old male: a brief case and review","volume":"5","author":"Kutky","year":"2018","journal-title":"Can J Kidney Health Dis."},{"key":"B9","doi-asserted-by":"publisher","first-page":"634","DOI":"10.3109\/0886022X.2014.883905","article-title":"Minimal change disease associated with newly diagnosed mantle cell lymphoma","volume":"36","author":"Khow","year":"2014","journal-title":"Ren Fail."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.1007\/s11255-012-0210-4","article-title":"Membranoproliferative glomerulonephritis, mantle cell lymphoma infiltration, and acute kidney injury","volume":"45","author":"Lubas","year":"2013","journal-title":"Int Urol Nephrol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"e238153","DOI":"10.1136\/bcr-2020-238153","article-title":"Proliferative glomerulonephritis and mantle cell lymphoma: a rare association","volume":"14","author":"Mhedhbi","year":"2021","journal-title":"BMJ Case Rep."},{"key":"B12","doi-asserted-by":"publisher","first-page":"9","DOI":"10.5414\/CNCS109036","article-title":"Antineutrophil cytoplasmic antibody-positive pauci-immune glomerulonephritis associated with mantle cell lymphoma","volume":"5","author":"Miyata","year":"2017","journal-title":"Clin Nephrol Case Stud."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1093\/rheumatology\/kez011","article-title":"Bidirectional relationship between systemic lupus erythematosus and non-Hodgkin's lymphoma: a nationwide population-based study","volume":"58","author":"Wang","year":"2019","journal-title":"Rheumatology (Oxford)."},{"key":"B14","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.1080\/0284186X.2019.1619936","article-title":"Autoimmune disease in patients with diffuse large B-cell lymphoma: occurrence and impact on outcome","volume":"58","author":"Morth","year":"2019","journal-title":"Acta Oncol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1093\/rheumatology\/kez088","article-title":"The relationship of lymphoma and lupus-at least bidirectional","volume":"58","author":"Schmalzing","year":"2019","journal-title":"Rheumatology (Oxford)."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2021.759279\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T12:27:32Z","timestamp":1638361652000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2021.759279\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,29]]},"references-count":15,"alternative-id":["10.3389\/fmed.2021.759279"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2021.759279","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,29]]},"article-number":"759279"}}