{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T23:23:23Z","timestamp":1794007403339,"version":"4.8.0"},"reference-count":23,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T00:00:00Z","timestamp":1638144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p><jats:bold>Purpose:<\/jats:bold> To evaluate the morphology changes of meibomian glands (MGs) after cataract surgery.<\/jats:p><jats:p><jats:bold>Setting:<\/jats:bold> Hangzhou Branch of the Eye Hospital of Wenzhou Medical University, Zhejiang, China.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> In this contra-lateral eye study, 40 patients received unilateral cataract surgery for age-related cataract. All the patients underwent the evaluation of non-invasive break-up time (NIBUT) and lower tear meniscus height (TMH) before the surgery and 6 months post-operatively. The MGs were evaluated via ImageJ and Meibomian Gland Bio-image Analyzer. MG dropout, length, width, area, gland diameter deformation index (DI), and gland signal index (SI) were recorded.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> MG length, width, area, DI, and SI were significantly decreased after cataract surgery in the study group (operated eyes, <jats:italic>P<\/jats:italic> &amp;lt; 0.001, <jats:italic>P<\/jats:italic> = 0.003, <jats:italic>P<\/jats:italic> &amp;lt; 0.001, <jats:italic>P<\/jats:italic> = 0.001, and <jats:italic>P<\/jats:italic> &amp;lt; 0.001, respectively) and showed no significant changes in the control group (non-operated eyes) (all <jats:italic>P<\/jats:italic> &amp;gt; 0.05). MG loss increased more in the study group (<jats:italic>P<\/jats:italic> = 0.030), and the changes in TMH and NIBUT were not significantly different between the two eyes (both <jats:italic>P<\/jats:italic> &amp;gt; 0.05).<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Cataract surgery aggravated meibomian gland morphology, such as MG loss, MG length, width, area, and SI, and produced no change in NIBUT and TMH at 6 months post-operatively.<\/jats:p>","DOI":"10.3389\/fmed.2021.766393","type":"journal-article","created":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T13:14:40Z","timestamp":1638364480000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":15,"title":["Meibomian Gland Morphology Changes After Cataract Surgery: A Contra-Lateral Eye 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