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Considering also the complexity of the therapeutic management of BS, that often includes biological off-label treatments, the participation in the therapeutic decision-making process of the BS patients is essential to ensure the integration of the care process into the life of the patient. For this reason, the empowerment of BS patients represents a crucial need and the present work is aimed at fully exploring all the potential variables implicated in the BS patient empowerment, also highlighting major points to consider and concrete actions to be planned in the immediate future in order to implement a pragmatic facilitation of the patients' empowerment.<\/jats:p>","DOI":"10.3389\/fmed.2021.769870","type":"journal-article","created":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T07:31:01Z","timestamp":1639380661000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["Empowering Patients in the Therapeutic Decision-Making Process: A Glance Into Beh\u00e7et's Syndrome"],"prefix":"10.3389","volume":"8","author":[{"given":"Diana","family":"Marinello","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Di Cianni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Del Bianco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Mattioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jurgen","family":"Sota","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Cantarini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giacomo","family":"Emmi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Leccese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Lopalco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Mosca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Padula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo","family":"Piga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Salvarani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenica","family":"Taruscio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosaria","family":"Talarico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2021,12,13]]},"reference":[{"key":"B1","article-title":"Geneva: World Health Organization","year":"2009"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1570","DOI":"10.1177\/193229681000400634","article-title":"Why patients should be more empowered: a european perspective on lessons learned in the management of diabetes","volume":"4","author":"Chatzimarkakis","year":"2010","journal-title":"J Diabetes Sci Technol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"2247","DOI":"10.3390\/ijerph18052247","article-title":"Enablers of patient knowledge empowerment for self-management of chronic disease: an integrative review","volume":"18","author":"Vainauskiene","year":"2021","journal-title":"Int J Environ Res Public Health."},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1007\/s43441-021-00282-z","article-title":"Sustaining meaningful patient engagement across the lifecycle of medicines: a roadmap for action","author":"Cavaller-Bellaubi","year":"2021","journal-title":"Ther Innov Regul Sci."},{"key":"B5","unstructured":"The impact of COVID-19 on rare and complex connective tissue diseases: the experience of ERN ReCONNET17784\n            TalaricoR\n            AguileraS\n            AlexanderT\n            AmouraZ\n            AntunesAM\n            ArnaudL\n          33408338Nat Rev Rheumatol.172021"},{"key":"B6","doi-asserted-by":"publisher","first-page":"2048","DOI":"10.1016\/S0140-6736(08)60875-2","article-title":"Empowerment of patients: lessons from the rare diseases community","volume":"371","author":"Aym\u00e9","year":"2008","journal-title":"Lancet."},{"key":"B7","doi-asserted-by":"publisher","first-page":"283","DOI":"10.4415\/ANN_19_03_15","article-title":"Patient empowerment of people living with rare diseases. 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