{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:04:46Z","timestamp":1753891486241,"version":"3.41.2"},"reference-count":18,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>There are no long-term (&amp;gt;10 years) follow-up evaluations of the effects of handstand exercise or studies on the use of equipment for passive handstand exercise.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To report a 40-year follow-up investigation of a Chinese man who has been practicing passive handstand for 40 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>This observational investigation was conducted in Guizhou Province, China.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participant<\/jats:title><jats:p>A (currently) 66-year-old Chinese man who had been practicing passive handstand exercise for 40 years was followed up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>Physical and auxiliary examinations were carried out to determine the effects of long-term passive handstand exercise on the human body.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main Measures<\/jats:title><jats:p>The participant\u2019s cerebrovascular, spinal health, mental health, and visual acuity as well as the presence of facial aging were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key Results<\/jats:title><jats:p>His cerebral vessels were healthy, he appeared younger than his peers, his cervical spondylosis improved, and his mental state and cognitive function were good.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Long-term passive handstand exercise can promote cerebrovascular elasticity training and delay signs of aging. We recommend promoting this passive handstand exercise to the public.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2022.752076","type":"journal-article","created":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T18:40:54Z","timestamp":1663958454000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Case Report: Passive Handstand Promotes Cerebrovascular Elasticity Training and Helps Delay the Signs of Aging: A 40-Year Follow-Up Investigation"],"prefix":"10.3389","volume":"9","author":[{"given":"Haonan","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengyong","family":"Si","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yidong","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,4,26]]},"reference":[{"key":"B1","first-page":"543","article-title":"The role of body position and gravity in the symptoms and treatment of various medical diseases.","volume":"134","author":"Martin-Du Pan","year":"2004","journal-title":"Swiss Med Wkly."},{"key":"B2","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1016\/j.neuint.2009.07.002","article-title":"Simulated microgravity promotes cellular senescence via oxidant stress in rat PC12 cells.","volume":"55","author":"Wang","year":"2009","journal-title":"Neurochem Int."},{"key":"B3","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1152\/jappl.1968.24.5.697","article-title":"Respiratory responses to headstand posture.","volume":"24","author":"Rao","year":"1968","journal-title":"J Appl Physiol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1152\/jappl.1963.18.5.987","article-title":"Cardiovascular responses to head-stand posture.","volume":"18","author":"Rao","year":"1963","journal-title":"J Appl Physiol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1152\/jappl.1962.17.1.117","article-title":"Metabolic cost of head-stand posture.","volume":"17","author":"Rao","year":"1962","journal-title":"J Appl Physiol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1016\/j.ophtha.2006.02.063","article-title":"Intraocular pressure changes and ocular biometry during Sirsasana (headstand posture) in yoga practitioners.","volume":"113","author":"Baskaran","year":"2006","journal-title":"Ophthalmology."},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-020-01638-z","article-title":"Valsalva retinopathy induced by handstand: a case report.","volume":"20","author":"Miyaki","year":"2020","journal-title":"BMC Ophthalmol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1007\/BF02850214","article-title":"Progression of glaucoma associated with the Sirsasana (headstand) yoga posture.","volume":"23","author":"Gallardo","year":"2006","journal-title":"Adv Ther."},{"key":"B9","doi-asserted-by":"publisher","first-page":"49","DOI":"10.2165\/00128071-200405010-00007","article-title":"The wrinkle severity rating scale: a validation study.","volume":"5","author":"Day","year":"2004","journal-title":"Am J Clin Dermatol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1016\/s0161-6420(13)38009-9","article-title":"Early treatment diabetic retinopathy study design and baseline patient characteristics. ETDRS Report Number 7.","volume":"98","year":"1991","journal-title":"Ophthalmology."},{"key":"B11","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-mental state\u201d. A practical method for grading the cognitive state of patients for the clinician.","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1056\/NEJMp2016814","article-title":"Health in aging-past, present, and future.","volume":"383","author":"Fried","year":"2020","journal-title":"N Engl J Med."},{"journal-title":"The Plan for Healthy China 2030.","year":"2016","key":"B13"},{"key":"B14","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/S1474-4422(18)30500-3","article-title":"Stroke in China: advances and challenges in epidemiology, prevention, and management.","volume":"18","author":"Wu","year":"2019","journal-title":"Lancet Neurol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"1390","DOI":"10.1177\/0271678X20956950","article-title":"Arterial elasticity, endothelial function and intracranial vascular health: a multimodal MRI study.","volume":"41","author":"Liu","year":"2021","journal-title":"J Cereb Blood Flow Metab."},{"key":"B16","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.arr.2017.05.006","article-title":"Vascular aging: molecular mechanisms and potential treatments for vascular rejuvenation.","volume":"37","author":"Mistriotis","year":"2017","journal-title":"Ageing Res Rev."},{"key":"B17","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.cger.2009.01.001","article-title":"Arterial compliance in the elderly: its effect on blood pressure measurement and cardiovascular outcomes.","volume":"25","author":"Lim","year":"2009","journal-title":"Clin Geriatr Med."},{"key":"B18","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/s0163-7258(96)00116-7","article-title":"Cerebral vessels in ageing and Alzheimer\u2019s disease.","volume":"72","author":"Kalaria","year":"1996","journal-title":"Pharmacol Ther."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2022.752076\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,23]],"date-time":"2022-09-23T18:41:00Z","timestamp":1663958460000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2022.752076\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,26]]},"references-count":18,"alternative-id":["10.3389\/fmed.2022.752076"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2022.752076","relation":{},"ISSN":["2296-858X"],"issn-type":[{"type":"electronic","value":"2296-858X"}],"subject":[],"published":{"date-parts":[[2022,4,26]]},"article-number":"752076"}}