{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T01:48:31Z","timestamp":1784339311549,"version":"3.55.0"},"reference-count":6,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T00:00:00Z","timestamp":1663113600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Splenomegaly is common in malaria, but splenic infarction is a rare complication of malaria. We report a case of a patient with <jats:italic>Plasmodium falciparum<\/jats:italic> infection who developed abdominal pain, reappearance of fever, elevated D-dimer during treatment, and abdominal CT confirmed splenic infarction. The abdominal pain was relieved and the fever subsided by analgesic and anticoagulant therapy. Six months later, abdominal CT showed splenic recovery. As a result, splenic infarction should be considered when a patient with malaria developed abdominal pain, reappearance of fever and elevated blood D-dimer during treatment. In the absence of surgical indications, conservative medical treatment is effective.<\/jats:p>","DOI":"10.3389\/fmed.2022.951812","type":"journal-article","created":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T04:57:12Z","timestamp":1663131432000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Splenic infarction during acute falciparum malaria: A case report"],"prefix":"10.3389","volume":"9","author":[{"given":"Youguang","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanshen","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,9,14]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1099\/jmm.0.05428-0","article-title":"Splenic complications in malaria: report of two cases from Turkey.","volume":"53","author":"Ozsoy","year":"2004","journal-title":"J Med Microbiol."},{"key":"B2","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/S1995-7645(13)60051-6","article-title":"Multiple splenic infarcts in acute Plasmodium vivax malaria: a rare case report.","volume":"6","author":"Aggarwal","year":"2013","journal-title":"Asian Pac J Trop Med."},{"key":"B3","first-page":"213","article-title":"Splenic infarction caused by vivax malaria.","volume":"75","author":"Cho","year":"2008","journal-title":"J Korean Surg Soc."},{"key":"B4","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.trstmh.2009.05.015","article-title":"A case series of splenic infarction during acute malaria in northwest Rajasthan, India.","volume":"104","author":"Gupta","year":"2010","journal-title":"Trans R Soc Med Hyg."},{"key":"B5","first-page":"362","article-title":"Splenic infarction:an update on William Osler\u2019s observation.","volume":"12","author":"Lawrence","year":"2010","journal-title":"Isr Med Assoc J."},{"key":"B6","first-page":"529","article-title":"Splenic infarction, rare cause of acute abdomen, only seldom requires splenectomy. Case report and literature review.","volume":"78","author":"Salvi","year":"2008","journal-title":"Ann Ital Chir."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2022.951812\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,14]],"date-time":"2022-09-14T04:57:17Z","timestamp":1663131437000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2022.951812\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,14]]},"references-count":6,"alternative-id":["10.3389\/fmed.2022.951812"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2022.951812","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,14]]},"article-number":"951812"}}