{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T22:01:04Z","timestamp":1788300064644,"version":"build-2803163510"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Vaginitis is the most common gynecologic diagnosis in primary care, and most women have at least one episode during their lives. The need for standardized strategies to diagnose and treat vaginitis, both in primary care and among gynecologists, is emphasized. The Brazilian Group for Vaginal Infections (GBIV, acronym in Portuguese) aimed to update the practical approach to affected women by reviewing and discussing recent literature, and developing algorithms for diagnosis and treatment of vaginitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature search within biomedical databases PubMed and SCieLo was conducted in January 2022. The available literature was evaluated by three experienced researchers, members of the GBIV, to summarize the main data and develop practical algorithms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results and conclusion<\/jats:title>\n                    <jats:p>Detailed algorithms were developed with the main goal to improve gynecological practice considering different scenarios and access to diagnostic tools, from the simplest to the most complex tests. Different age groups and specific contexts were also considered. The combination of anamnesis, gynecological examination, and complementary tests remains the basis of a proper diagnostic and therapeutic approach. Periodic updates of these algorithms are warranted as new evidence becomes available.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fmed.2023.1040072","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T05:25:36Z","timestamp":1675920336000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":17,"title":["Diagnosis and treatment of infectious vaginitis: Proposal for a new algorithm"],"prefix":"10.3389","volume":"10","author":[{"suffix":"Jr.","given":"Jos\u00e9","family":"Eleut\u00e9rio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana Bittencourt","family":"Campaner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Newton Sergio","family":"de Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-020-0347-4","article-title":"Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review.","volume":"19","author":"Kalia","year":"2020","journal-title":"Ann Clin Microbiol Antimicrob."},{"key":"B2","first-page":"321","article-title":"Vaginitis: Diagnosis and treatment.","volume":"97","author":"Paladine","year":"2018","journal-title":"Am Fam Physician."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1093\/infdis\/jiz342","article-title":"An updated conceptual model on the pathogenesis of bacterial vaginosis.","volume":"220","author":"Muzny","year":"2019","journal-title":"J Infect Dis."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1001\/jama.291.11.1368","article-title":"Evaluation of vaginal complaints.","volume":"291","author":"Anderson","year":"2004","journal-title":"JAMA."},{"key":"B5","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1097\/AOG.0b013e3181909f63","article-title":"Accuracy of the clinical diagnosis of vaginitis compared with a DNA probe laboratory standard.","volume":"113","author":"Lowe","year":"2009","journal-title":"Obstet Gynecol."},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-593-2020","article-title":"Brazilian protocol for sexually transmitted infections, 2020: infections causing vaginal discharge.","volume":"30","author":"De Carvalho","year":"2021","journal-title":"Epidemiol Serv Saude."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1097\/AOG.0000000000000551","article-title":"Management of persistent vaginitis.","volume":"124","author":"Nyirjesy","year":"2014","journal-title":"Obstet Gynecol."},{"key":"B8","year":"2014","journal-title":"Oxfordshire Clinical Commissioning Group. 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