{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T15:47:23Z","timestamp":1788364043300,"version":"build-2803163510"},"reference-count":12,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T00:00:00Z","timestamp":1680566400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>A superficial cervical vaginal myofibroblastoma is a rare mesenchymal tumor, originating from the superficial stroma of the vagina and cervix. This study reports a patient, who was diagnosed with endometrioid carcinoma and a concomitant benign superficial cervicovaginal myofibroblastoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 53-year-old female with endometrial carcinoma was admitted to the Department of Gynecology of our hospital. She had a history of breast cancer on May 23, 2010, and took toremifene citrate for 41\u2009months. Radical resection of the endometrial carcinoma was performed at our hospital. Based on the pathological findings, she was postoperatively diagnosed with endometrial adenocarcinoma with superficial cervical vaginal myofibroblastoma. The patient continued receiving postoperative breast cancer treatment. She underwent follow-up for 23\u2009months. No recurrence or metastasis of the endometrial cancer or superficial cervical vaginal myofibroblastoma was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There were similarities between superficial cervical vaginal myofibroblastoma and other mesenchymal tumors of the female genital tract. Superficial cervical vaginal myofibroblastomas have a good prognosis, and the combination of tissue morphology and immunohistochemistry helped establish a definitive diagnosis.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2023.1160273","type":"journal-article","created":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T04:29:43Z","timestamp":1680582583000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Case report: Superficial cervicovaginal myofibroblastoma of the cervix with endometrial carcinoma"],"prefix":"10.3389","volume":"10","author":[{"given":"Xiaowei","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bifei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junqiang","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,4,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1053\/hupa.2001.25588","article-title":"Superficial cervicovaginal myofibroblastoma: fourteen cases of a distinctive mesenchymal tumor arising from the specialized subepithelial stroma of the lower female genital tract","volume":"32","author":"Laskin","year":"2001","journal-title":"Hum Pathol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1024173","DOI":"10.3389\/fonc.2022.1024173","article-title":"Superficial vaginal myofibroblastoma with mushroom-like appearance: a case report with colposcopic findings and literature review","volume":"12","author":"Wang","year":"2022","journal-title":"Front Oncol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1111\/j.1365-2559.2005.02063.x","article-title":"Superficial myofibroblastoma of the lower female genital tract: report of a series including tumours with a vulval location","volume":"46","author":"Ganesan","year":"2005","journal-title":"Histopathology"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"152010","DOI":"10.1016\/j.anndiagpath.2022.152010","article-title":"Superficial myofibroblastoma of the lower female genital tract: a clinicopathological analysis of 15 cases","volume":"60","author":"Zhang","year":"2022","journal-title":"Ann Diagn Pathol"},{"key":"ref5","first-page":"165","article-title":"Vaginal superficial myofibroblastoma. 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A clinicopathologic study of 10 cases","volume":"43","author":"Magro","year":"2012","journal-title":"Hum Pathol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1080\/00313020500058284","article-title":"Superficial cervico-vaginal myofibroblastoma: a report of five cases","volume":"37","author":"Stewart","year":"2005","journal-title":"Pathology"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1160273\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T04:29:47Z","timestamp":1680582587000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1160273\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,4]]},"references-count":12,"alternative-id":["10.3389\/fmed.2023.1160273"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2023.1160273","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,4]]},"article-number":"1160273"}}