{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T09:07:15Z","timestamp":1782205635904,"version":"3.54.5"},"reference-count":36,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T00:00:00Z","timestamp":1684972800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Long-term impairments after sepsis can impede the return to work in survivors. We aimed to describe rates of return to work 6 and 12\u2009months postsepsis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective, population-based cohort study was based on health claims data of the German AOK health insurance of 23.0 million beneficiaries. We included 12-months survivors after hospital-treated sepsis in 2013\/2014, who were \u226460 years at the time of the admission and were working in the year presepsis. We assessed the prevalence of return to work (RTW), persistent inability to work and early retirement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 7,370 working age sepsis survivors, 69.2% returned to work at 6\u2009months postsepsis, while 22.8% were on sick leave and 8.0% retired early. At 12\u2009months postsepsis, the RTW rate increased to 76.9%, whereas 9.8% were still on sick leave and 13.3% retired early. Survivors who returned to work had a mean of 70 (SD 93) sick leave days in the 12\u2009months presepsis (median 28\u2009days, IQR 108\u2009days).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>One out of four working age sepsis survivors does not resume work in the year postsepsis. Specific rehabilitation and targeted aftercare may be opportunities to reduce barriers to RTW after sepsis.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2023.1187809","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T04:56:05Z","timestamp":1684990565000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Return to work after sepsis\u2014a German population-based health claims study"],"prefix":"10.3389","volume":"10","author":[{"given":"Carolin","family":"Fleischmann-Struzek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianka","family":"Ditscheid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norman","family":"Rose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Spoden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Wedekind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Schlattmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"G\u00fcnster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad","family":"Reinhart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane S.","family":"Hartog","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"Freytag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/S0140-6736(19)32989-7","article-title":"Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the global burden of disease study","volume":"395","author":"Rudd","year":"2020","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1097\/01.ccm.0000194535.82812.ba","article-title":"The effect of age on the development and outcome of adult sepsis","volume":"34","author":"Martin","year":"2006","journal-title":"Crit Care Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1007\/s11136-018-2028-8","article-title":"What matters most to sepsis survivors: a qualitative analysis to identify specific health-related quality of life domains","volume":"28","author":"Konig","year":"2019","journal-title":"Qual Life Res"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1001\/jama.2017.17687","article-title":"Enhancing recovery from Sepsis: a review","volume":"319","author":"Prescott","year":"2018","journal-title":"JAMA"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"e2134290","DOI":"10.1001\/jamanetworkopen.2021.34290","article-title":"Epidemiology and costs of Postsepsis morbidity, nursing care dependency, and mortality in Germany, 2013 to 2017","volume":"4","author":"Fleischmann-Struzek","year":"2021","journal-title":"JAMA Netw Open"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1111\/j.1399-6576.2009.01921.x","article-title":"Long-term physical outcome in patients with septic shock","volume":"53","author":"Poulsen","year":"2009","journal-title":"Acta Anaesthesiol Scand"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"82","DOI":"10.2105\/ajph.94.1.82","article-title":"Unemployment and mental health: understanding the interactions among gender, family roles, and social class","volume":"94","author":"Artazcoz","year":"2004","journal-title":"Am J Public Health"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1513\/AnnalsATS.201903-248OC","article-title":"Return to employment after critical illness and its association with psychosocial outcomes. 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