{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:15:50Z","timestamp":1790306150978,"version":"4.1.0"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T00:00:00Z","timestamp":1692144000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess the motivations and perceptions of the general public in the United Kingdom toward donating their uterus for Uterus Transplantation after death (UTx).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A cross sectional study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>A 32-item electronic questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Population<\/jats:title><jats:p>One hundred fifty nine females over the age of 16 living in the United Kingdom, consented and took part in the study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The motivations and perceptions toward UTx among the general public including the willingness to donate and barriers preventing donation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred fifty nine women completed the questionnaire. The majority had never heard of UTx (<jats:italic>n<\/jats:italic>\u2009=\u2009107, 71%) and most were not aware the uterus could be donated after death (<jats:italic>n<\/jats:italic>\u2009=\u2009130, 92%). 43% of the cohort were willing to donate their uterus after death (<jats:italic>n<\/jats:italic>\u2009=\u200957). 8% stated they wished to donate their organs but not their uterus (<jats:italic>n<\/jats:italic>\u2009=\u200910). 30% of women (<jats:italic>n<\/jats:italic>\u2009=\u200942) believed the child born following UTx would have genetic links to the donor. Over half of the respondents (<jats:italic>n<\/jats:italic>\u2009=\u200965, 51%) strongly agreed or agreed they would feel joy in the knowledge that donation would lead to bringing a new life into the world. A quarter of respondents strongly agreed or agreed (<jats:italic>n<\/jats:italic>\u2009=\u200945, 25%) that the use of their uterus by another woman would feel like an extension of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings indicate a favorable opinion toward UTx and a positive attitude toward donation of the uterus after death among the general public in the United Kingdom. The findings also highlight the need for education around UTx now this therapeutic option is available.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2023.1223228","type":"journal-article","created":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T12:49:25Z","timestamp":1692276565000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Attitudes, knowledge, and perceptions among women toward uterus transplantation and donation in the United Kingdom"],"prefix":"10.3389","volume":"10","author":[{"given":"Saaliha","family":"Vali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin P.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sairah","family":"Sheikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srdjan","family":"Saso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Quiroga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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Increasing the acceptability and rates of organ donation among minority ethnic groups: a programme of observational and evaluative research on donation, transplantation and ethnicity (DonaTE)\n            MorganM\n            KentenC\n            DeedatS\n            FarsidesB\n            NewtonT\n            RandhawaG\n          Southampton (UK)NIHR Journals Library Copyright \u00a9 Queen\u2019s Printer and Controller of HMSO 20162016"},{"key":"ref27","article-title":"Annual report on the potential donor AUDIT","year":"2021"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1007\/s10943-010-9374-3","article-title":"Religion and organ donation: the views of UK faith leaders","volume":"51","author":"Randhawa","year":"2012","journal-title":"J Relig Health"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1177\/15269248211046027","article-title":"Motivations and psychological characteristics of nondirected uterus donors from the Dallas UtErus transplant study","volume":"31","author":"Warren","year":"2021","journal-title":"Prog Transplant"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1080\/07481180290106607","article-title":"Post-mortem organ donation and grief: a study of consent, refusal and well-being in bereavement","volume":"26","author":"Cleiren","year":"2002","journal-title":"Death Stud"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1080\/07481180600923257","article-title":"Parental grief following the brain death of a child: does consent or refusal to organ donation affect their grief?","volume":"30","author":"Bellali","year":"2006","journal-title":"Death Stud"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1097\/00006842-199803000-00007","article-title":"The stability of family decisions to consent or refuse organ donation: would you do it again?","volume":"60","author":"Burroughs","year":"1998","journal-title":"Psychosom Med"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"56","DOI":"10.7182\/pit2015552","article-title":"Survey of perceptions of health care professionals in the United Kingdom toward uterine transplant","volume":"25","author":"Saso","year":"2015","journal-title":"Prog Transplant"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1223228\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T12:49:30Z","timestamp":1692276570000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1223228\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,16]]},"references-count":33,"alternative-id":["10.3389\/fmed.2023.1223228"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2023.1223228","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,16]]},"article-number":"1223228"}}