{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T15:39:06Z","timestamp":1760369946217,"version":"3.41.2"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T00:00:00Z","timestamp":1696982400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the accuracy of using the vergence formula to screen myopia in children and adolescents.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a cross-sectional study conducted between December 2022 and May 2023 at the ophthalmology clinic of Beijing Tongren Hospital. A total of 336 children aged 6 to 12\u2009years with refractive errors were selected according to the inclusion criteria. Biometric measurements, including axial length, corneal thickness, anterior chamber depth, corneal curvature, and lens thickness, were obtained using a biometer. The Calculated spherical equivalent (SE) was then calculated using the vergence formula. Cycloplegic refraction was performed after paralysis of the ciliary muscle, and the subjective SE was recorded. A diagnosis of myopia was made if the subjective SE was \u2264 \u22120.50 diopters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The AL\/CR, subjective SE, and calculated SE were not normally distributed (<jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.05). The AL\/CR value was 3.08 (2.81, 3.27), the SE was \u22121.60 D (\u22126.00 D, 3.75 D), and the calculated SE was \u22121.42 D (\u22126.64 D, 5.73 D). There was no significant difference between the calculated SE and the SE (<jats:italic>Z<\/jats:italic>\u2009=\u2009\u22122.899, <jats:italic>p<\/jats:italic>\u2009=\u20090.004). The AL\/CR value was negatively correlated with SE (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.687, <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.01), and the calculated SE was positively correlated with SE (<jats:italic>r<\/jats:italic>\u2009=\u20090.827, <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.01). The area under the ROC curve for predicting myopia using AL\/CR and calculated SE was 0.876 and 0.962, respectively, and the difference between the two was significant (<jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001). The sensitivity of AL\/CR was 84.2%, the specificity was 70.6%, the accuracy was 82.1%, and the Youden index was 0.548. The sensitivity of calculated SE was 83.1%, the specificity was 100%, the accuracy was 85.7%, and the Youden index was 0.831.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The vergence formula can be used to evaluate myopia in children and adolescents with relatively high accuracy without cycloplegic refraction.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2023.1233080","type":"journal-article","created":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T06:47:07Z","timestamp":1697006827000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The accuracy of using vergence formula to screen myopia in children: a cross-sectional study"],"prefix":"10.3389","volume":"10","author":[{"given":"Zhen","family":"Yi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huang","family":"Haikuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wang","family":"Xinxin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,10,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1167\/iovs.62.5.6","article-title":"IMI prevention of myopia and its progression","volume":"62","author":"Jonas","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"933","DOI":"10.21037\/tp-22-226","article-title":"Clinical evaluation 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