{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T23:45:52Z","timestamp":1778024752564,"version":"3.51.4"},"reference-count":16,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T00:00:00Z","timestamp":1703203200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the efficacy of hysteroscopic hysteroplasty in the treatment of uterine malformation complicated by primary reproductive disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Women with unexplained primary infertility, repeated <jats:italic>in vitro<\/jats:italic> fertilization (IVF) failure or repeated spontaneous abortion, and uterine malformations unrelated to diethylstilbestrol who visited the obstetrics and gynecology department of our hospital from January 2019 to December 2022 were included in the prospective cohort study. Uterine malformation in the patients was confirmed by three-dimensional ultrasound and diagnostic hysteroscopy. Hysteroscopic hysteroplasty was performed using a 5-mm diameter hysteroscope and 5-FR surgical scissors, and after 3 months, palliative care was proposed for patients with unexplained infertility or repeated spontaneous abortion, and after 6 months, IVF treatment was recommended for patients with repeated <jats:italic>in vitro<\/jats:italic> fertilization (IVF) failures, with a planned minimum follow-up time of 1 year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 83 women enrolled in the study, including 33 cases of primary infertility, 29 cases of repeated spontaneous abortion, and 21 cases of repeated IVF failure. No complications occurred during the hysteroscopic surgery. During the follow-up period, the clinical pregnancy rate of the women enrolled in the study increased to 77.1%, the live birth rate went up to 79.7%, the fetus delivered at full term accounted for 64.1%, and the cesarean section rate was 27.5%. The miscarriage rate was 9.4%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hysteroscopic hysteroplasty can improve the reproductive outcomes in women with primary reproductive disorders and uterine malformations.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2023.1269733","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T04:12:27Z","timestamp":1703218347000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Hysteroscopic hysteroplasty for the treatment of T-shaped uteri in women with reproductive failure"],"prefix":"10.3389","volume":"10","author":[{"given":"Lu","family":"Ying","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Du","family":"Shangping","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhou","family":"Tong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Liguo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tong","family":"Qiaoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,12,22]]},"reference":[{"key":"B1","first-page":"1542","article-title":"Analysis of pregnancy outcome of assisted reproduction in patients with infertility and uterine malformation","volume":"28","author":"Jiao","year":"2020","journal-title":"Chin J Eugen Genetic."},{"key":"B2","first-page":"1277","article-title":"A case of mediastinal uterus malformation with double incomplete cervix and full-term pregnancy","volume":"36","author":"Wang","year":"2020","journal-title":"China Med Imag Technol."},{"key":"B3","first-page":"852","article-title":"Analysis of pregnancy outcome of infertility patients with uterine malformation after transuterine laparoscopic surgery","volume":"29","author":"Li","year":"2020","journal-title":"J Reprod Med."},{"key":"B4","first-page":"94","article-title":"Analysis of the case of intrauterine abscess caused by Escherichia coli infection in non-pregnant uterus after delivery of single-vagina, double-cervix and double-uterus malformation","volume":"11","author":"Wang","year":"2019","journal-title":"China Family Plan Obstetr Gynecol."},{"key":"B5","first-page":"93","article-title":"Study and analysis of the effect of ultrasound-guided curettage on pregnant women with uterine malformation","volume":"17","author":"Xian","year":"2019","journal-title":"Contemporary Med J."},{"key":"B6","first-page":"134","article-title":"Analysis of pregnancy outcome in patients with congenital uterine malformation complicated with pregnancy","volume":"21","author":"Sheng","year":"2017","journal-title":"J Prac Clin Med."},{"key":"B7","first-page":"429","article-title":"Study on the correlation between 97 cases of congenital uterine malformation and abnormal pregnancy","volume":"26","author":"Sheng","year":"2017","journal-title":"J Armed Police Logistic."},{"key":"B8","first-page":"402","article-title":"Effect of congenital uterine malformation on pregnancy outcome","volume":"17","author":"Jiang","year":"2017","journal-title":"J Trop Med."},{"key":"B9","first-page":"45","article-title":"Clinical analysis of 40 cases of uterine malformation pregnancy outcome","volume":"4","author":"Lin","year":"2017","journal-title":"J Prac Gynecol Endocrinol."},{"key":"B10","volume-title":"Clinical Outcome Analysis of 139 Cases of Late Pregnancy of Pregnant Women With Double Uterus Malformation","author":"Chen","year":"2018"},{"key":"B11","doi-asserted-by":"publisher","first-page":"128","DOI":"10.3390\/jcm9092857","article-title":"Dysmorphic uteri: obstetric results after hysteroscopic office metroplasty in infertile and recurrent pregnancy loss patients. a prospective observational study","volume":"9","author":"M\u00f3nica","year":"2020","journal-title":"J Clin Med."},{"key":"B12","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.fertnstert.2017.06.005","article-title":"The international glossary on infertility and fertility care, 2017","volume":"5","author":"Zegers-Hochschild","year":"2017","journal-title":"Hum Reprod."},{"key":"B13","first-page":"822","article-title":"Subtypes of T-shaped uteri","volume":"27","author":"Alonso 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trials","volume":"23","author":"Vitagliano","year":"2019","journal-title":"Fertil Steril."}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1269733\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T04:12:36Z","timestamp":1703218356000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1269733\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,22]]},"references-count":16,"alternative-id":["10.3389\/fmed.2023.1269733"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2023.1269733","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,22]]},"article-number":"1269733"}}