{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T11:46:30Z","timestamp":1793879190322,"version":"4.7.0"},"reference-count":70,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T00:00:00Z","timestamp":1703116800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The assessment of the relative impacts of uterine artery embolization (UAE) treatment for female patients is a critical field that informs clinical decisions, yet there is a noticeable scarcity of high-quality, long-term comparative studies. This meta-analysis aimed to focus on the pregnancy rate and outcomes in female patients following UAE and to conduct subgroup analyses based on different patient populations or various control treatments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic literature search was conducted on 2 August 2023 through the Web of Science, PubMed, Embase, and the Cochrane Library of Clinical Trials for all potential studies. Relative risks (RRs) with 95% confidence intervals (CIs) were applied to compare pregnancy rates and outcomes between the UAE group and the control group. Heterogeneity was evaluated statistically by using the chi-square-based Cochran\u2019s Q test and Higgins I<jats:sup>2<\/jats:sup> statistics, and 95% prediction interval (PI). Software R 4.3.1 and Stata 12.0 were used for meta-analysis. The trial sequential analysis (TSA) was performed with TSA v0.9.5.10 Beta software.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 15 eligible studies (11 cohort studies, 3 randomized controlled trials, and 1 non-randomized clinical trial) were included in this meta-analysis. The overall results revealed that UAE significantly decreased postoperative pregnancy rate [RR (95% CI): 0.721 (0.531\u20130.979), 95% PI: 0.248\u20132.097] and was associated with an increased risk of postoperative PPH [RR (95% CI): 3.182 (1.319\u20137.675), 95% PI: 0.474\u201322.089]. Analysis grouped by population indicated that UAE decreased the risk of preterm delivery [RR (95% CI): 0.326 (0.128\u20130.831), <jats:italic>p<\/jats:italic>\u2009=\u20090.019] and cesarean section [RR (95% CI): 0.693 (0.481\u20130.999), <jats:italic>p<\/jats:italic>\u2009=\u20090.050] and increased the risk of placenta previa [RR (95% CI): 8.739 (1.580\u201348.341), <jats:italic>p<\/jats:italic>\u2009=\u20090.013] in patients with UFs, CSP, and PPH, respectively. When compared with myomectomy, HIFU, and non-use of UAE, UAE treatment was associated with the reduced risks of preterm delivery [RR (95% CI): 0.296 (0.106\u20130.826)] and cesarean section [(95% CI): 0.693 (0.481\u20130.999), <jats:italic>p<\/jats:italic>\u2009=\u20090.050] and increased placenta previa risk [RR (95% CI): 10.682 (6.859\u201316.636)], respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>UAE treatment was associated with a lower postoperative pregnancy rate and increased risk of PPH. Subgroup analysis suggested that UAE was shown to decrease the risk of preterm delivery and cesarean section and increase placenta previa risk.<\/jats:p><jats:p><jats:bold>Systematic review registration:<\/jats:bold><jats:ext-link>https:\/\/www.crd.york.ac.uk\/prospero\/<\/jats:ext-link>, Identifier CRD42023448257.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2023.1283279","type":"journal-article","created":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T04:42:52Z","timestamp":1703133772000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":18,"title":["Pregnancy rate and outcomes after uterine artery embolization for women: a systematic review and meta-analysis with trial sequential analysis"],"prefix":"10.3389","volume":"10","author":[{"given":"Xiaoli","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guolin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinghui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,12,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1007\/s00404-021-06347-6","article-title":"The effect of prophylactic uterine artery embolization on reproductive outcomes in patients with cesarean scar pregnancy: a propensity score-matched study","volume":"305","author":"Wang","year":"2022","journal-title":"Arch Gynecol Obstet"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1016\/j.bpobgyn.2017.09.003","article-title":"Uterine artery embolization: a review of current concepts","volume":"46","author":"Keung","year":"2018","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1056\/NEJMoa1914735","article-title":"Uterine-artery embolization or myomectomy for uterine fibroids","volume":"383","author":"Manyonda","year":"2020","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.jvir.2021.12.004","article-title":"Utilization and comparative effectiveness of uterine artery embolization versus hysterectomy for severe postpartum hemorrhage: a National Inpatient Sample Study","volume":"33","author":"Webster","year":"2022","journal-title":"J Vasc Interv Radiol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1007\/s11547-022-01536-y","article-title":"Endovascular treatment of cesarean scar pregnancy: a retrospective multicentric study","volume":"127","author":"Failla","year":"2022","journal-title":"Radiol Med"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.2214\/ajr.11.8362","article-title":"Complication rates and effectiveness of uterine artery embolization in the treatment of symptomatic leiomyomas: a systematic review and meta-analysis","volume":"199","author":"Toor","year":"2012","journal-title":"AJR Am J Roentgenol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1097\/gco.0000000000000635","article-title":"Updates in uterine artery embolization for leiomyomas","volume":"32","author":"Kim","year":"2020","journal-title":"Curr Opin Obstet Gynecol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1007\/s00270-020-02521-6","article-title":"Pregnancy and its outcomes in patients after uterine fibroid embolization: a systematic review and Meta-analysis","volume":"43","author":"Ghanaati","year":"2020","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1097\/AOG.0b013e318183fbab","article-title":"Alternatives to hysterectomy in the management of leiomyomas","volume":"112","year":"2008","journal-title":"Obstet Gynecol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1016\/j.jvir.2014.08.029","article-title":"Quality improvement guidelines for uterine artery embolization for symptomatic leiomyomata","volume":"25","author":"Dariushnia","year":"2014","journal-title":"J Vasc Interv Radiol"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"2155077","DOI":"10.1080\/02656736.2022.2155077","article-title":"HIFU as an alternative modality for patients with uterine fibroids who require fertility-sparing treatment","volume":"40","author":"Li","year":"2023","journal-title":"Int J Hyperth"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"16914","DOI":"10.1038\/s41598-021-96273-z","article-title":"A systematic review and meta-analysis of obstetric and maternal outcomes after prior uterine artery embolization","volume":"11","author":"Matsuzaki","year":"2021","journal-title":"Sci Rep"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1002\/uog.19070","article-title":"Influence of prenatal diagnosis of abnormally invasive placenta on maternal outcome: systematic review and meta-analysis","volume":"52","author":"Buca","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1002\/uog.20131","article-title":"Role of interventional radiology in pregnancy complicated by placenta accreta spectrum disorder: systematic review and meta-analysis","volume":"53","author":"D'Antonio","year":"2019","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher","year":"2009","journal-title":"BMJ"},{"key":"ref16","first-page":"7","volume-title":"The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in Meta-analyses","author":"Wells","year":"2014"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"681232","DOI":"10.3389\/fmed.2021.681232","article-title":"Prevalence of sarcopenia and its association with diabetes: a Meta-analysis of community-dwelling Asian population","volume":"8","author":"Chung","year":"2021","journal-title":"Front Med"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Control Clin Trials"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1186\/1471-2288-11-41","article-title":"Quantifying, displaying and accounting for heterogeneity in the meta-analysis of RCTs using standard and generalised Q statistics","volume":"11","author":"Bowden","year":"2011","journal-title":"BMC Med Res Methodol"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"e010247","DOI":"10.1136\/bmjopen-2015-010247","article-title":"Plea for routinely presenting prediction intervals in meta-analysis","volume":"6","author":"IntHout","year":"2016","journal-title":"BMJ Open"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"1539","DOI":"10.1002\/sim.1186","article-title":"Quantifying heterogeneity in a meta-analysis","volume":"21","author":"Higgins","year":"2002","journal-title":"Stat Med"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"Egger","year":"1997","journal-title":"BMJ"},{"key":"ref23","first-page":"1088","article-title":"Operating characteristics of a rank correlation test for publication bias","volume-title":"Biometrics","author":"Begg","year":"1994"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1111\/j.0006-341x.2000.00455.x","article-title":"Trim and fill: a simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"Duval","year":"2000","journal-title":"Biometrics"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s12874-017-0315-7","article-title":"Trial sequential analysis in systematic reviews with meta-analysis","volume":"17","author":"Wetterslev","year":"2017","journal-title":"BMC Med Res Methodol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"2574","DOI":"10.1016\/j.fertnstert.2010.02.052","article-title":"Fertility after embolization of the uterine arteries to treat obstetrical hemorrhage: a review of 53 cases","volume":"94","author":"Hardeman","year":"2010","journal-title":"Fertil Steril"},{"key":"ref27","first-page":"21187","article-title":"Efficacy of transvaginal debridement and repair surgery for cesarean scar pregnancy: a cohort study compared with uterine artery embolism","volume":"8","author":"Chen","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1097\/aog.0000000000002331","article-title":"Comparative effectiveness of uterine leiomyoma procedures using a large insurance claims database","volume":"130","author":"Borah","year":"2017","journal-title":"Obstet Gynecol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s00270-007-9195-2","article-title":"Midterm clinical and first reproductive results of a randomized controlled trial comparing uterine fibroid embolization and myomectomy","volume":"31","author":"Mara","year":"2008","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1056\/NEJMoa062003","article-title":"Uterine-artery embolization versus surgery for symptomatic uterine fibroids","volume":"356","author":"Edwards","year":"2007","journal-title":"N Engl J Med"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1111\/jog.14129","article-title":"Recurrence of post-partum hemorrhage in women with a history of uterine artery embolization","volume":"46","author":"Imafuku","year":"2020","journal-title":"J Obstet Gynaecol Res"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1016\/j.jmig.2018.09.001","article-title":"Analysis of the reproductive outcome of patients with cesarean scar pregnancy treated by high-intensity focused ultrasound and uterine artery embolization: a retrospective cohort study","volume":"26","author":"Chen","year":"2019","journal-title":"J Minim Invasive Gynecol"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"100139","DOI":"10.1016\/j.eurox.2021.100139","article-title":"Uterine artery embolization or myomectomy for women with uterine fibroids: four-year follow-up of a randomised controlled trial","volume":"13","author":"Daniels","year":"2021","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"ref34","doi-asserted-by":"publisher","first-page":"2007","DOI":"10.1111\/jog.14067","article-title":"Complications and reproductive outcome after uterine artery embolization for retained products of conception","volume":"45","author":"Ohmaru-Nakanishi","year":"2019","journal-title":"J Obstet Gynaecol Res"},{"key":"ref35","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1186\/s12884-023-05376-0","article-title":"Clinical efficacy and re-pregnancy outcomes of patients with previous cesarean scar pregnancy treated with either high-intensity focused ultrasound or uterine artery embolization before ultrasound-guided dilatation and curettage: a retrospective cohort study","volume":"23","author":"Wang","year":"2023","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"151","DOI":"10.2147\/ijwh.S236443","article-title":"Obstetric outcomes of pregnancy after uterine artery embolization","volume":"12","author":"Jitsumori","year":"2020","journal-title":"Int J Women's Health"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"e0185467","DOI":"10.1371\/journal.pone.0185467","article-title":"Previous uterine artery embolization increases the rate of repeat embolization in a subsequent pregnancy","volume":"12","author":"Cho","year":"2017","journal-title":"PLoS One"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"2265","DOI":"10.1016\/j.ejrad.2013.08.045","article-title":"Outcome of uterine artery embolization versus MR-guided high-intensity focused ultrasound treatment for uterine fibroids: long-term results","volume":"82","author":"Froeling","year":"2013","journal-title":"Eur J Radiol"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"990066","DOI":"10.3389\/fmed.2022.990066","article-title":"Comparison of high-intensity focused ultrasound ablation and uterine artery embolization in the management of cervical pregnancy","volume":"9","author":"Li","year":"2022","journal-title":"Front Med"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1007\/s00270-012-0388-y","article-title":"Uterine artery embolization versus laparoscopic uterine artery occlusion: the outcomes of a prospective, nonrandomized clinical trial","volume":"35","author":"Mara","year":"2012","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref41","doi-asserted-by":"publisher","first-page":"1337234","DOI":"10.1155\/2022\/1337234","article-title":"Effect of uterine artery ligation and uterine artery embolization on postpartum hemorrhage due to uterine asthenia after cesarean section and its effect on blood flow and function of uterine and ovarian arteries","volume":"2022","author":"Liu","year":"2022","journal-title":"J Healthcare Engineer"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"3359","DOI":"10.1080\/14767058.2020.1818218","article-title":"Prophylactic intraoperative uterine artery embolization for the management of major placenta previa","volume":"35","author":"Radaelli","year":"2022","journal-title":"J Maternal-Fetal Neonatal Med"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1793","DOI":"10.1111\/1471-0528.16781","article-title":"Uterine artery embolisation or myomectomy for women with uterine fibroids wishing to avoid hysterectomy: a cost-utility analysis of the FEMME trial","volume":"128","author":"Rana","year":"2021","journal-title":"BJOG"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"h4887","DOI":"10.1136\/bmj.h4887","article-title":"Fibroids: diagnosis and management","volume":"351","author":"Lumsden","year":"2015","journal-title":"BMJ"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"205","DOI":"10.5114\/pm.2016.65665","article-title":"The influence of uterine artery embolisation on ovarian reserve, fertility, and pregnancy outcomes\u2014a review of literature","volume":"15","author":"Czuczwar","year":"2016","journal-title":"Przeglad menopauzalny = Menopause Rev"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1186\/s12958-018-0432-0","article-title":"Radiations and female fertility","volume":"16","author":"Marci","year":"2018","journal-title":"Reprod Biol Endocrinol"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"403.e1","DOI":"10.1016\/j.ajog.2021.05.033","article-title":"Clinical investigation of fertility after uterine artery embolization","volume":"225","author":"Serres-Cousine","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"3361","DOI":"10.1210\/clinem\/dgaa513","article-title":"Anti-M\u00fcllerian hormone and ovarian reserve: update on assessing ovarian function","volume":"105","author":"Moolhuijsen","year":"2020","journal-title":"J Clin Endocrinol Metab"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1016\/j.ogc.2012.09.005","article-title":"The impact and management of fibroids for fertility: an evidence-based approach","volume":"39","author":"Guo","year":"2012","journal-title":"Obstet Gynecol Clin N Am"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1007\/s00270-019-02321-7","article-title":"Impact of patient and procedure-related factors on radiation exposure from uterine artery embolization","volume":"43","author":"Lacayo","year":"2020","journal-title":"Cardiovasc Intervent Radiol"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1016\/j.ijrobp.2008.12.016","article-title":"Impact of radiotherapy on fertility, pregnancy, and neonatal outcomes in female cancer patients","volume":"73","author":"Wo","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1016\/j.rbmo.2021.06.027","article-title":"Mouse model of radiation-induced premature ovarian insufficiency reveals compromised oocyte quality: implications for fertility preservation","volume":"43","author":"Puy","year":"2021","journal-title":"Reprod Biomed Online"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"e0277052","DOI":"10.1371\/journal.pone.0277052","article-title":"A predictive model of the effect of therapeutic radiation on the human ovary","volume":"17","author":"Kelsey","year":"2022","journal-title":"PLoS One"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"4340","DOI":"10.1200\/jco.2007.15.2884","article-title":"Spontaneous abortion in a Danish population-based cohort of childhood cancer survivors","volume":"26","author":"Winther","year":"2008","journal-title":"J Clin Oncol"},{"key":"ref55","doi-asserted-by":"publisher","first-page":"623","DOI":"10.2147\/ijwh.S43591","article-title":"Embolization of uterine fibroids from the point of view of the gynecologist: pros and cons","volume":"6","author":"Mara","year":"2014","journal-title":"Int J Women's Health"},{"key":"ref56","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/13645706.2015.1074082","article-title":"Fertility after uterine artery embolization: a review","volume":"25","author":"McLucas","year":"2016","journal-title":"Minimally Invas Ther Allied Technol"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"426","DOI":"10.1016\/s0029-7844(01)01762-8","article-title":"Predictors of subsequent surgery for uterine leiomyomata after abdominal myomectomy","volume":"99","author":"Stewart","year":"2002","journal-title":"Obstet Gynecol"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1016\/j.jvir.2013.03.014","article-title":"Uterine artery embolization and its effect on fertility","volume":"24","author":"Mohan","year":"2013","journal-title":"J Vasc Interv Radiol"},{"key":"ref59","doi-asserted-by":"publisher","first-page":"Cd005073","DOI":"10.1002\/14651858.CD005073.pub3","article-title":"Uterine artery embolization for symptomatic uterine fibroids","volume":"5","author":"Gupta","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1097\/gco.0000000000000808","article-title":"Caesarean scar pregnancy: diagnosis, natural history and treatment","volume":"34","author":"No\u00ebl","year":"2022","journal-title":"Curr Opin Obstet Gynecol"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"83","DOI":"10.2147\/tcrm.S184387","article-title":"Analysis on clinical effects of dilation and curettage guided by ultrasonography versus hysteroscopy after uterine artery embolization in the treatment of cesarean scar pregnancy","volume":"15","author":"Qiu","year":"2019","journal-title":"Ther Clin Risk Manag"},{"key":"ref62","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.tjog.2015.03.009","article-title":"Systematic review: what is the best first-line approach for cesarean section ectopic pregnancy?","volume":"55","author":"Kanat-Pektas","year":"2016","journal-title":"Taiwan J Obstet Gynecol"},{"key":"ref63","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1093\/humrep\/deg168","article-title":"Fertility and pregnancy outcome following pelvic arterial embolization for severe post-partum haemorrhage. A cohort study","volume":"18","author":"Salomon","year":"2003","journal-title":"Hum Reprod"},{"key":"ref64","doi-asserted-by":"publisher","first-page":"460","DOI":"10.3390\/jcm9020460","article-title":"An introduction to high intensity focused ultrasound: Systematic Review on Principles, Devices, and Clinical Applications","volume":"9","author":"Izadifar","year":"2020","journal-title":"J Clin Med"},{"key":"ref65","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/j.fertnstert.2008.10.001","article-title":"Pregnancy outcome after magnetic resonance-guided focused ultrasound surgery (MRgFUS) for conservative treatment of uterine fibroids","volume":"93","author":"Rabinovici","year":"2010","journal-title":"Fertil Steril"},{"key":"ref66","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1111\/1471-0528.14691","article-title":"Should we be putting our scalpels down? Is HIFU the answer to fertility-sparing fibroid treatment?","volume":"125","author":"Tempest","year":"2018","journal-title":"BJOG"},{"key":"ref67","doi-asserted-by":"publisher","first-page":"229.e1","DOI":"10.1016\/j.ajog.2013.10.872","article-title":"Patterns of recurrence of postpartum hemorrhage in a large population-based cohort","volume":"210","author":"Oberg","year":"2014","journal-title":"Am J Obstet Gynecol"},{"key":"ref68","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1097\/01.gco.0000233934.13684.cb","article-title":"Pregnancy outcomes following treatment for fibroids: uterine fibroid embolization versus laparoscopic myomectomy","volume":"18","author":"Goldberg","year":"2006","journal-title":"Curr Opin Obstet Gynecol"},{"key":"ref69","doi-asserted-by":"publisher","first-page":"576.e1","DOI":"10.1016\/j.ajog.2015.06.063","article-title":"Outcome of pregnancies after pelvic artery embolization for postpartum hemorrhage: retrospective cohort study","volume":"213","author":"Poggi","year":"2015","journal-title":"Am J Obstet Gynecol"},{"key":"ref70","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1016\/j.fertnstert.2013.02.013","article-title":"Fertility rate and subsequent pregnancy outcomes after conservative surgical techniques in postpartum hemorrhage: 15 years of literature","volume":"99","author":"Gizzo","year":"2013","journal-title":"Fertil Steril"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1283279\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,21]],"date-time":"2023-12-21T04:43:00Z","timestamp":1703133780000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1283279\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,21]]},"references-count":70,"alternative-id":["10.3389\/fmed.2023.1283279"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2023.1283279","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,21]]},"article-number":"1283279"}}