{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:51:19Z","timestamp":1777596679551,"version":"3.51.4"},"reference-count":30,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T00:00:00Z","timestamp":1701907200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p><jats:italic>Comamonas kerstersii<\/jats:italic> (<jats:italic>C. kerstersii<\/jats:italic>) is a Gram-negative bacterium that was initially thought to be non-pathogenic to humans and is abundant in the environment. In recent years, with the availability of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) that enable fast and accurate bacterial identification, there have been increasing number of reports of human infections caused by <jats:italic>C. kerstersii<\/jats:italic>, indicating that this organism has emerged as human pathogen. In fact, most clinical isolates of <jats:italic>C. kerstersii<\/jats:italic> are recovered from peritoneal liquid, and bacteremia has been infrequently reported. Here, we report a case of bacteremia caused by <jats:italic>C. kerstersii<\/jats:italic> in a 28-year-old male patient with acute perforated appendicitis and localized peritonitis and present a comprehensive review of <jats:italic>C. kerstersii<\/jats:italic> infections in pathogenic diagnosis and clinical treatment as well as prognosis, thus providing a better understanding of <jats:italic>C. kerstersii<\/jats:italic>-related infections.<\/jats:p>","DOI":"10.3389\/fmed.2023.1283769","type":"journal-article","created":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T15:16:17Z","timestamp":1701962177000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":8,"title":["Bacteremia caused by Comamonas kerstersii in a patient with acute perforated appendicitis and localized peritonitis: case report and literature review"],"prefix":"10.3389","volume":"10","author":[{"given":"Yingmiao","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lifeng","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongxin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,12,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1099\/ijs.0.02450-0","article-title":"Description 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