{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:09:49Z","timestamp":1770743389091,"version":"3.49.0"},"reference-count":5,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T00:00:00Z","timestamp":1702857600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>Keloidal scleroderma is a variant of scleroderma that presents as firm keloidal nodules or plaques. Due to the similarity in morphology and pathology, it is often distinguished from a hypertrophic scar or keloid. We report a case of keloidal scleroderma with rare nodular and diffuse spindle cell infiltration in histopathology. Recognition of this unusual histopathological feature may help clinicians improve their knowledge and avoid misdiagnosis.<\/jats:p>","DOI":"10.3389\/fmed.2023.1291941","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T15:01:16Z","timestamp":1702911676000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Nodular and diffuse spindle cell infiltration in keloidal scleroderma: a case report"],"prefix":"10.3389","volume":"10","author":[{"given":"Yiting","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yibin","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zile","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu","family":"Nie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhouwei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,12,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1111\/ced.12196","article-title":"Keloid-Like Morphoea","volume":"39","author":"Salmon","year":"2014","journal-title":"Clin Exp Dermatol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1097\/dad.0000000000001629","article-title":"Morphea with Keloidal features: a case report and review of the literature","volume":"42","author":"Yu","year":"2020","journal-title":"Am J Dermatopathol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1066","DOI":"10.1001\/jamadermatol.2022.3241","article-title":"Firm red-Brown plaques in a patient with systemic scleroderma","volume":"158","author":"Zacher","year":"2022","journal-title":"JAMA Dermatol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1111\/j.1600-0560.1992.tb01348.x","article-title":"Dermatomyofibroma. A benign cutaneous, plaque-like proliferation of fibroblasts and Myofibroblasts in young adults","volume":"19","author":"Kamino","year":"1992","journal-title":"J Cutan Pathol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1111\/1346-8138.14161","article-title":"Diagnostic criteria, severity classification and guidelines of localized scleroderma","volume":"45","author":"Asano","year":"2018","journal-title":"J Dermatol"}],"container-title":["Frontiers in Medicine"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1291941\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T15:01:19Z","timestamp":1702911679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmed.2023.1291941\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,18]]},"references-count":5,"alternative-id":["10.3389\/fmed.2023.1291941"],"URL":"https:\/\/doi.org\/10.3389\/fmed.2023.1291941","relation":{},"ISSN":["2296-858X"],"issn-type":[{"value":"2296-858X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,18]]},"article-number":"1291941"}}