{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:18:48Z","timestamp":1787026728463,"version":"build-2736575974"},"reference-count":141,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T00:00:00Z","timestamp":1705449600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:p>\n                    Pregnancies resulting from assisted reproductive techniques (ART) are increasingly prevalent worldwide. While most pregnancies conceived through\n                    <jats:italic>in-vitro<\/jats:italic>\n                    fertilization (IVF) progress without complications, mounting evidence suggests that these pregnancies are at a heightened risk of adverse perinatal outcomes. Specifically, IVF pregnancies involving oocyte donation have garnered attention due to numerous reports indicating an elevated risk profile for pregnancy-related complications within this subgroup of patients. The precise mechanisms contributing to this increased risk of complications remain incompletely understood. Nonetheless, it is likely that they are mediated by an abnormal immune response at the fetal\u2013maternal interface. Additionally, these outcomes may be influenced by baseline patient characteristics, such as the etiology of infertility, absence of corpus luteum, and variations in endometrial preparation protocols, among other factors. This review aims to succinctly summarize the most widely accepted mechanisms that potentially contribute to the onset of placental dysfunction in pregnancies conceived through oocyte donation.\n                  <\/jats:p>","DOI":"10.3389\/fmed.2024.1338516","type":"journal-article","created":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T23:39:26Z","timestamp":1705448366000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Pregnancies through oocyte donation. A mini review of pathways involved in placental dysfunction"],"prefix":"10.3389","volume":"11","author":[{"given":"Javier","family":"Caradeux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjam\u00edn","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"\u00c1vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"Valenzuela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauricio","family":"Mondi\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Figueras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,1,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1016\/j.fertnstert.2023.01.013","article-title":"Global fertility care with assisted reproductive technology","volume":"120","author":"Adamson","year":"2023","journal-title":"Fertil Steril"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1093\/humupd\/dmaa047","article-title":"IVF and other ART in low-and middle-income countries: a systematic landscape analysis","volume":"27","author":"Chiware","year":"2021","journal-title":"Hum Reprod Update"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1080\/14647273.2021.1957503","article-title":"Socioeconomic status and fertility treatment outcomes in high-income countries: a review of the current literature","volume":"26","author":"Imrie","year":"2023","journal-title":"Hum Fertil"},{"key":"ref4","author":"Adamson","year":"2018"},{"key":"ref5","year":""},{"key":"ref6","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1093\/humupd\/dmv016","article-title":"Infertility around the globe: new thinking on gender, reproductive technologies and global movements in the 21st century","volume":"21","author":"Inhorn","year":"2015","journal-title":"Hum Reprod Update"},{"key":"ref7","year":"2019"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.bpobgyn.2018.07.001","article-title":"Single embryo transfer for all","volume":"53","author":"Cutting","year":"2018","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.fertnstert.2021.01.043","article-title":"Perinatal outcomes in singleton pregnancies after in vitro fertilization cycles over 24 years","volume":"116","author":"Shah","year":"2021","journal-title":"Fertil Steril"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s00404-016-4250-3","article-title":"Worldwide prevalence of adverse pregnancy outcomes among singleton pregnancies after in vitro fertilization\/intracytoplasmic sperm injection: a systematic review and meta-analysis","volume":"295","author":"Qin","year":"2017","journal-title":"Arch Gynecol Obstet"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1002\/uog.18930","article-title":"Risk of spontaneous preterm birth in singleton pregnancies conceived after IVF\/ICSI treatment: meta-analysis of cohort studies","volume":"51","author":"Cavoretto","year":"2018","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1111\/1471-0528.15509","article-title":"Risk of stillbirth in low-risk singleton term pregnancies following fertility treatment: a national cohort study","volume":"126","author":"Bay","year":"2019","journal-title":"BJOG"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1987","DOI":"10.1080\/14767058.2020.1771690","article-title":"IVF\/ICSI treatment and the risk of iatrogenic preterm birth in singleton pregnancies: systematic review and meta-analysis of cohort studies","volume":"35","author":"Cavoretto","year":"2020","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1186\/s12884-021-03938-8","article-title":"Assisted reproductive technology and hypertensive disorders of pregnancy: systematic review and meta-analyses","volume":"21","author":"Chih","year":"2021","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1016\/j.fertnstert.2021.04.007","article-title":"Assisted reproductive technologies and the risk of stillbirth in singleton pregnancies: a systematic review and meta-analysis","volume":"116","author":"Sarmon","year":"2021","journal-title":"Fertil Steril"},{"key":"ref16","first-page":"B2","article-title":"Publications Committee. 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