{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T15:55:12Z","timestamp":1783612512364,"version":"3.55.0"},"reference-count":51,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Med."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Myopia is a significant public health problem across the globe. This study aimed to examine the regional disparity in prevalence and correlated factors of myopia in children and adolescents in two typical regions, Gannan Tibetan Autonomous Prefecture (Gannan Prefecture for short, a Tibetan residential area) and Wuwei City (a Han residential area) in Gansu Province, China, and to provide a reference for the prevention and control of regional myopia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was a cross-sectional study of children and adolescents in Gansu Province, China. A total of 6,187 (Wuwei City: 3,266, Gannan Tibetan Autonomous Prefecture: 2,921) students were selected by stratified cluster sampling. Eye examinations and questionnaires were administered to the participants. Myopia is defined as a condition in which the spherical equivalent refractive error of an eye is less than or equal to \u22120.50 D when ocular accommodation is relaxed. The \u03c7<jats:sup>2<\/jats:sup> test and multivariate logistic regression analysis were used to analyze the correlated factors of myopia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The myopia rate of 6,187 students was 71.4%, and students had a higher rate of myopia (77.5%) in Wuwei City compared to Gannan Prefecture (64.6%) (<jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.001). The results of multivariate analysis in Wuwei City showed that girls (odds ratio (<jats:italic>OR<\/jats:italic>)\u2009=\u20091.325), junior students (<jats:italic>OR<\/jats:italic>\u2009=\u20092.542), senior students(<jats:italic>OR<\/jats:italic>\u2009=\u20094.605), distance between eyes and book less than one foot (<jats:italic>OR<\/jats:italic>\u2009=\u20091.291), and parents with myopia (one, <jats:italic>OR<\/jats:italic>\u2009=\u20092.437; two, <jats:italic>OR<\/jats:italic>\u2009=\u20094.453) had higher risks of myopia (all, <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.05). For Gannan Prefecture, girls (<jats:italic>OR<\/jats:italic>\u2009=\u20091.477), senior students (<jats:italic>OR<\/jats:italic>\u2009=\u20091.537), daily time spent doing homework \u22652\u2009h (OR\u2009=\u20091.420), the distance between eyes and book less than one foot (<jats:italic>OR<\/jats:italic>\u2009=\u20091.205), mean time continuous eye use (0.25\u2013&amp;lt;0.5\u2009h, <jats:italic>OR<\/jats:italic>\u2009=\u20091.345, 0.5\u2013&amp;lt;1\u2009h, <jats:italic>OR<\/jats:italic>\u2009=\u20091.317, \u22651\u2009h, <jats:italic>OR<\/jats:italic>\u2009=\u20091.313), average daily sleep duration &amp;lt;8\u2009h (<jats:italic>OR<\/jats:italic>\u2009=\u20091.399), and parents with myopia (one, <jats:italic>OR<\/jats:italic>\u2009=\u20091.852; two, <jats:italic>OR<\/jats:italic>\u2009=\u20092.913) had higher risks of myopia (all, <jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of myopia is at a relatively high level in Gansu Province. The prevalence and risk factors for myopia vary by region.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fmed.2024.1375080","type":"journal-article","created":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T05:15:57Z","timestamp":1722489357000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Regional disparities in the prevalence and correlated factors of myopia in children and adolescents in Gansu, China"],"prefix":"10.3389","volume":"11","author":[{"given":"Jinyu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiqi","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yali","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,8,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"M20","DOI":"10.1167\/iovs.18-25957","article-title":"IMI-defining and classifying myopia: a proposed set of standards for clinical and epidemiologic studies","volume":"60","author":"Flitcroft","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1167\/iovs.61.4.49","article-title":"The complications of myopia: a review and meta-analysis","volume":"61","author":"Haarman","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/j.ophtha.2018.10.029","article-title":"Potential lost productivity resulting from the global burden association of myopia: systematic review, Mata-analysis, and modeling","volume":"126","author":"Naidoo","year":"2019","journal-title":"Ophthalmology"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","article-title":"Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050","volume":"123","author":"Holden","year":"2016","journal-title":"Ophthalmol"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"855","DOI":"10.3238\/arztebl.2020.0855","article-title":"Prevalence and time trends in myopia among children and adolescents","volume":"117","author":"Schuster","year":"2020","journal-title":"Dtsch Arztebl Int"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1136\/bjophthalmol-2018-313325","article-title":"Risk factors associated with myopia in schoolchildren in Ireland","author":"Harrington","year":"2019","journal-title":"Br J Ophthalmol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1001\/jamaophthalmol.2019.3103","article-title":"Current prevalence of myopia and association of myopia with environmental factors among schoolchildren in Japan","volume":"137","author":"Yotsukura","year":"2019","journal-title":"JAMA Ophthalmol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"e0207690","DOI":"10.1371\/journal.pone.0207690","article-title":"On behalf of the epidemiologic survey Committee of the Korean Ophthalmologic Society. 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